Works by Doering, Christopher B.

Results: 19

Directing the migration of serum-free, ex vivo-expanded Vγ9Vδ2 T cells.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1331322

By:

Parwani, Kiran K.;
Branella, Gianna M.;
Burnham, Rebecca E.;
Burnham, Andre J.;
Schiaffino Bustamante, Austre Y.;
Foppiani, Elisabetta Manuela;
Knight, Kristopher A.;
Petrich, Brian G.;
Horwitz, Edwin M.;
Doering, Christopher B.;
Spencer, H. Trent

Publication type:

Article

Ligand-based targeting of c-kit using engineered γδ T cells as a strategy for treating acute myeloid leukemia.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1294555

By:

Branella, Gianna M.;
Lee, Jasmine Y.;
Okalova, Jennifer;
Parwani, Kiran K.;
Alexander, Jordan S.;
Arthuzo, Raquel F.;
Fedanov, Andrew;
Bing Yu;
McCarty, David;
Brown, Harrison C.;
Chandrakasan, Shanmuganathan;
Petrich, Brian G.;
Doering, Christopher B.;
Spencer, H. Trent

Publication type:

Article

Dissecting the cellular components of ex vivo γδ T cell expansions to optimize selection of potent cell therapy donors for neuroblastoma immunotherapy trials.

Published in:

OncoImmunology, 2022, v. 11, n. 1, p. 1, doi. 10.1080/2162402X.2022.2057012

By:

Jonus, Hunter C.;
Burnham, Rebecca E.;
Ho, Andrew;
Pilgrim, Adeiye A.;
Shim, Jenny;
Doering, Christopher B.;
Spencer, H. Trent;
Goldsmith, Kelly C.

Publication type:

Article

Ex vivo expanded patient-derived γδ T-cell immunotherapy enhances neuroblastoma tumor regression in a murine model.

Published in:

OncoImmunology, 2019, v. 8, n. 8, p. N.PAG, doi. 10.1080/2162402X.2019.1593804

By:

Zoine, Jaquelyn T.;
Knight, Kristopher A.;
Fleischer, Lauren C.;
Sutton, Kathryn S.;
Goldsmith, Kelly C.;
Doering, Christopher B.;
Spencer, H. Trent

Publication type:

Article

Development of chimeric antigen receptors targeting T-cell malignancies using two structurally different anti-CD5 antigen binding domains in NK and CRISPR-edited T cell lines.

Published in:

OncoImmunology, 2018, v. 7, n. 3, p. 1, doi. 10.1080/2162402X.2017.1407898

By:

Raikar, Sunil S.;
Fleischer, Lauren C.;
Moot, Robert;
Fedanov, Andrew;
Paik, Na Yoon;
Knight, Kristopher A.;
Doering, Christopher B.;
Trent Spencer, H.

Publication type:

Article

Transplanting FVIII/ET3-secreting cells in fetal sheep increases FVIII levels long-term without inducing immunity or toxicity.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39986-1

By:

Rodriguez, Martin;
Trevisan, Brady;
Ramamurthy, Ritu M.;
George, Sunil K.;
Diaz, Jonathan;
Alexander, Jordan;
Meares, Diane;
Schwahn, Denise J.;
Quilici, David R.;
Figueroa, Jorge;
Gautreaux, Michael;
Farland, Andrew;
Atala, Anthony;
Doering, Christopher B.;
Spencer, H. Trent;
Porada, Christopher D.;
Almeida-Porada, Graça

Publication type:

Article

Functional aspects of factor VIII expression after transplantation of genetically-modified hematopoietic stem cells for hemophilia A.

Published in:

Journal of Gene Medicine, 2010, v. 12, n. 4, p. 333, doi. 10.1002/jgm.1442

By:

Ide, Lucienne M.;
Iwakoshi, Neal N.;
Gangadharan, Bagirath;
Jobe, Shawn;
Moot, Robert;
McCarty, David;
Doering, Christopher B.;
Spencer, H. Trent

Publication type:

Article

Lentiviral Vector Platform for Production of Bioengineered Recombinant Coagulation Factor VIII.

Published in:

Molecular Therapy, 2011, v. 19, n. 2, p. 302, doi. 10.1038/mt.2010.239

By:

Spencer, H. Trent;
Denning, Gabriela;
Gautney, Richard E.;
Dropulic, Boro;
Roy, Andre J.;
Baranyi, Lajos;
Gangadharan, Bagirath;
Parker, Ernest T.;
Lollar, Pete;
Doering, Christopher B.

Publication type:

Article

Directed Engineering of a High-expression Chimeric Transgene as a Strategy for Gene Therapy of Hemophilia A.

Published in:

Molecular Therapy, 2009, v. 17, n. 7, p. 1145, doi. 10.1038/mt.2009.35

By:

Doering, Christopher B.;
Denning, Gabriela;
Dooriss, Kerry;
Gangadharan, Bagirath;
Johnston, Jennifer M.;
Kerstann, Keith W.;
McCarty, David A.;
Spencer, H. Trent

Publication type:

Article

Hematopoietic Stem Cells Encoding Porcine Factor VIII Induce Pro-coagulant Activity in Hemophilia A Mice with Pre-existing Factor VIII Immunity.

Published in:

Molecular Therapy, 2007, v. 15, n. 6, p. 1093, doi. 10.1038/sj.mt.6300146

By:

Doering, Christopher B.;
Gangadharan, Bagirath;
Dukart, Hillary Z.;
Spencer, H. Trent

Publication type:

Article

Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor.

Published in:

Nature Communications, 2016, v. 7, n. 9, p. 12863, doi. 10.1038/ncomms12863

By:

Deng, Wei;
Xu, Yan;
Chen, Wenchun;
Paul, David S.;
Syed, Anum K.;
Dragovich, Matthew A.;
Liang, Xin;
Zakas, Philip;
Berndt, Michael C.;
Di Paola, Jorge;
Ware, Jerry;
Lanza, Francois;
Doering, Christopher B.;
Bergmeier, Wolfgang;
Zhang, X. Frank;
Li, Renhao

Publication type:

Article

Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.697602

By:

Ronayne, Estelle K.;
Peters, Shaun C.;
Gish, Joseph S.;
Wilson, Celena;
Spencer, H. Trent;
Doering, Christopher B.;
Lollar, Pete;
Spiegel Jr, P. Clint;
Childers, Kenneth C.

Publication type:

Article

Development and Characterization of Recombinant Ovine Coagulation Factor VIII.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049481

By:

Zakas, Philip M.;
Gangadharan, Bagirath;
Almeida-Porada, Graca;
Porada, Christopher D.;
Spencer, H. Trent;
Doering, Christopher B.

Publication type:

Article

Potentiation of Thrombin Generation in Hemophilia A Plasma by Coagulation Factor VIII and Characterization of Antibody-Specific Inhibition.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0048172

By:

Doshi, Bhavya S.;
Gangadharan, Bagirath;
Doering, Christopher B.;
Meeks, Shannon L.

Publication type:

Article

A Lentiviral Gene Therapy Strategy for the In Vitro Production of Feline Erythropoietin.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045099

By:

Vapniarsky, Natalia;
Lame, Michael;
McDonnel, Samantha;
Murphy, Brian;
Doering, Christopher B.

Publication type:

Article

Chemical Chaperones Improve Protein Secretion and Rescue Mutant Factor VIII in Mice with Hemophilia A.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044505

By:

Roth, Stefanie D.;
Schüttrumpf, Jörg;
Milanov, Peter;
Abriss, Daniela;
Ungerer, Christopher;
Quade-Lyssy, Patricia;
Simpson, Jeremy C.;
Pepperkok, Rainer;
Seifried, Erhard;
Tonn, Torsten;
Doering, Christopher B.

Publication type:

Article

The Immune Response to the fVIII Gene Therapy in Preclinical Models.

Published in:

Frontiers in Immunology, 2020, p. 1, doi. 10.3389/fimmu.2020.00494

By:

Patel, Seema R.;
Lundgren, Taran S.;
Spencer, H. Trent;
Doering, Christopher B.

Publication type:

Article

Neutralizing Antibodies Against Factor VIII Can Occur Through a Non-Germinal Center Pathway.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.880829

By:

Patel, Seema R.;
Lundgren, Taran S.;
Baldwin, Wallace Hunter;
Cox, Courtney;
Parker, Ernest T.;
Healey, John F.;
Jajosky, Ryan P.;
Zerra, Patricia E.;
Josephson, Cassandra D.;
Doering, Christopher B.;
Stowell, Sean R.;
Meeks, Shannon L.

Publication type:

Article

Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction.

Published in:

Nature Biotechnology, 2017, v. 35, n. 1, p. 35, doi. 10.1038/nbt.3677

By:

Zakas, Philip M;
Brown, Harrison C;
Knight, Kristopher;
Meeks, Shannon L;
Spencer, H Trent;
Gaucher, Eric A;
Doering, Christopher B

Publication type:

Article