Works by Dobson, Renwick C. J.

Results: 49

Structural and biophysical analysis of a Haemophilus influenzae tripartite ATP-independent periplasmic (TRAP) transporter.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.92307

By:

Currie, Michael J.;
Davies, James S.;
Scalise, Mariafrancesca;
Gulati, Ashutosh;
Wright, Joshua D.;
Newton-Vesty, Michael C.;
Abeysekera, Gayan S.;
Subramanian, Ramaswamy;
Wahlgren, Weixiao Y.;
Friemann, Rosmarie;
Allison, Jane R.;
Mace, Peter D.;
Griffin, Michael D. W.;
Demeler, Borries;
Wakatsuki, Soichi;
Drew, David;
Indiveri, Cesare;
Dobson, Renwick C. J.;
North, Rachel A.

Publication type:

Article

Inhibition of Arabidopsis growth by the allelopathic compound azetidine-2-carboxylate is due to the low amino acid specificity of cytosolic prolyl-tRNA synthetase.

Published in:

Plant Journal, 2016, v. 88, n. 2, p. 236, doi. 10.1111/tpj.13246

By:

Lee, Jiyeon;
Joshi, Naveen;
Pasini, Rita;
Dobson, Renwick C. J.;
Allison, Jane;
Leustek, Thomas

Publication type:

Article

The Molecular Basis for Escherichia coli O157:H7 Phage FAHEc1 Endolysin Function and Protein Engineering to Increase Thermal Stability.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 6, p. 1101, doi. 10.3390/v13061101

By:

Love, Michael J.;
Coombes, David;
Manners, Sarah H.;
Abeysekera, Gayan S.;
Billington, Craig;
Dobson, Renwick C. J.

Publication type:

Article

Enzyme Kinetics Analysis: An online tool for analyzing enzyme initial rate data and teaching enzyme kinetics.

Published in:

Biochemistry & Molecular Biology Education, 2024, v. 52, n. 3, p. 348, doi. 10.1002/bmb.21823

By:

Mak, Daniel A.;
Dunn, Sebastian;
Coombes, David;
Carere, Carlo R.;
Allison, Jane R.;
Nock, Volker;
Hudson, André O.;
Dobson, Renwick C. J.

Publication type:

Article

Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus.

Published in:

FEBS Letters, 2019, v. 593, n. 1, p. 52, doi. 10.1002/1873-3468.13289

By:

Davies, James S.;
Coombes, David;
Horne, Christopher R.;
Pearce, F. Grant;
Friemann, Rosmarie;
North, Rachel A.;
Dobson, Renwick C. J.

Publication type:

Article

Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus.

Published in:

FEBS Letters, 2016, v. 590, n. 23, p. 4414, doi. 10.1002/1873-3468.12462

By:

North, Rachel A.;
Watson, Andrew J. A.;
Pearce, F. Grant;
Muscroft-Taylor, Andrew C.;
Friemann, Rosmarie;
Fairbanks, Antony J.;
Dobson, Renwick C. J.

Publication type:

Article

The Quest for Novel Antimicrobial Compounds: Emerging Trends in Research, Development, and Technologies.

Published in:

Antibiotics (2079-6382), 2019, v. 8, n. 1, p. 8, doi. 10.3390/antibiotics8010008

By:

Mantravadi, Pavan K.;
Kalesh, Karunakaran A.;
Dobson, Renwick C. J.;
Hudson, André O.;
Parthasarathy, Anutthaman

Publication type:

Article

Potential for Bacteriophage Endolysins to Supplement or Replace Antibiotics in Food Production and Clinical Care.

Published in:

Antibiotics (2079-6382), 2018, v. 7, n. 1, p. 17, doi. 10.3390/antibiotics7010017

By:

Love, Michael J.;
Bhandari, Dinesh;
Dobson, Renwick C. J.;
Billington, Craig

Publication type:

Article

Crystal structures and kinetic analyses of N‐acetylmannosamine‐6‐phosphate 2‐epimerases from Fusobacterium nucleatum and Vibrio cholerae.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2018, v. 74, n. 7, p. 431, doi. 10.1107/S2053230X18008543

By:

Manjunath, Lavanyaa;
Guntupalli, Sai Rohit;
Currie, Michael J.;
North, Rachel A.;
Dobson, Renwick C. J.;
Nayak, Vinod;
Subramanian, Ramaswamy

Publication type:

Article

The crystal structure of dihydrodipicolinate reductase from the human-pathogenic bacterium Bartonella henselae strain Houston-1 at 2.3 Å resolution.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 12, p. 885, doi. 10.1107/S2053230X16018525

By:

Cala, Ali R.;
Nadeau, Maria T.;
Abendroth, Jan;
Staker, Bart L.;
Reers, Alexandra R.;
Weatherhead, Anthony W.;
Dobson, Renwick C. J.;
Myler, Peter J.;
Hudson, André O.

Publication type:

Article

Cloning, expression, purification, crystallization and X-ray diffraction analysis of dihydrodipicolinate synthase from the human pathogenic bacterium Bartonella henselae strain Houston-1 at 2.1 Å resolution.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 1, p. 2, doi. 10.1107/S2053230X15023213

By:

Naqvi, Kubra F.;
Staker, Bart L.;
Dobson, Renwick C. J.;
Serbzhinskiy, Dmitry;
Sankaran, Banumathi;
Myler, Peter J.;
Hudson, André O.

Publication type:

Article

A new lysine biosynthetic enzyme from a bacterial endosymbiont shaped by genetic drift and genome reduction.

Published in:

Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 7, p. 1, doi. 10.1002/pro.5083

By:

Gilkes, Jenna M.;
Frampton, Rebekah A.;
Board, Amanda J.;
Hudson, André O.;
Price, Thomas G.;
Morris, Vanessa K.;
Crittenden, Deborah L.;
Muscroft‐Taylor, Andrew C.;
Sheen, Campbell R.;
Smith, Grant R.;
Dobson, Renwick C. J.

Publication type:

Article

Effects of Beneficial Mutations in pykF Gene Vary over Time and across Replicate Populations in a Long-Term Experiment with Bacteria.

Published in:

Molecular Biology & Evolution, 2018, v. 35, n. 1, p. 202, doi. 10.1093/molbev/msx279

By:

Peng, Fen;
Widmann, Scott;
Wünsche, Andrea;
Duan, Kristina;
Donovan, Katherine A;
Dobson, Renwick C J;
Lenski, Richard E;
Cooper, Tim F

Publication type:

Article

Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.98158

By:

Goyal, Parveen;
Dhanabalan, KanagaVijayan;
Scalise, Mariafrancesca;
Friemann, Rosmarie;
Indiveri, Cesare;
Dobson, Renwick C. J.;
Vinothkumar, Kutti R.;
Ramaswamy, Subramanian

Publication type:

Article

Identification and Partial Characterization of a Novel UDP-N-Acetylenolpyruvoylglucosamine Reductase/UDP-N-Acetylmuramate:L-Alanine Ligase Fusion Enzyme from Verrucomicrobium spinosum DSM 4136T.

Published in:

Frontiers in Microbiology, 2016, p. 1, doi. 10.3389/fmicb.2016.00362

By:

Naqvi, Kubra F.;
Wheatley, Matthew S.;
Savka, Michael A.;
Hudson, André O.;
Patin, Delphine;
Barreteau, Hélène;
Blanot, Didier;
Mengin-Lecreulx, Dominique;
Dobson, Renwick C. J.;
Han Ming Gan

Publication type:

Article

L,L-diaminopimelate aminotransferase (DapL): a putative target for the development of narrow-spectrum antibacterial compounds.

Published in:

Frontiers in Microbiology, 2014, v. 5, p. 1, doi. 10.3389/fmicb.2014.00509

By:

Triassi, Alexander J.;
Wheatley, Matthew S.;
Savka, Michael A.;
Hudson, André O.;
Han Ming Gan;
Dobson, Renwick C. J.

Publication type:

Article

Quaternary variations in the structural assembly of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella multocida.

Published in:

Proteins, 2021, v. 89, n. 1, p. 81, doi. 10.1002/prot.25996

By:

Manjunath, Lavanyaa;
Coombes, David;
Davies, James;
Dhurandhar, Mugdha;
Tiwari, Vikas R.;
Dobson, Renwick C. J.;
Sowdhamini, R.;
Ramaswamy, S.;
Bose, Sucharita

Publication type:

Article

On the structure and function of Escherichia coli YjhC: An oxidoreductase involved in bacterial sialic acid metabolism.

Published in:

Proteins, 2020, v. 88, n. 5, p. 654, doi. 10.1002/prot.25846

By:

Horne, Christopher R.;
Kind, Laura;
Davies, James S.;
Dobson, Renwick C. J.

Publication type:

Article

Cover Image, Volume 88, Issue 5.

Published in:

Proteins, 2020, v. 88, n. 5, p. C1, doi. 10.1002/prot.25721

By:

Horne, Christopher R.;
Kind, Laura;
Davies, James S.;
Dobson, Renwick C. J.

Publication type:

Article

Identification of the bona fide DHDPS from a common plant pathogen.

Published in:

Proteins, 2014, v. 82, n. 9, p. 1869, doi. 10.1002/prot.24539

By:

Atkinson, Sarah C.;
Hor, Lilian;
Dogovski, Con;
Dobson, Renwick C. J.;
Perugini, Matthew A.

Publication type:

Article

The crystal structure of dihydrodipicolinate synthase from Escherichia coli with bound pyruvate and succinic acid semialdehyde: Unambiguous resolution of the stereochemistry of the condensation product.

Published in:

Proteins, 2012, v. 80, n. 8, p. 2117, doi. 10.1002/prot.24106

By:

Boughton, Berin A.;
Dobson, Renwick C. J.;
Hutton, Craig A.

Publication type:

Article

Capillaric field effect transistors.

Published in:

Microsystems & Nanoengineering, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41378-022-00360-8

By:

Meffan, Claude;
Menges, Julian;
Dolamore, Fabian;
Mak, Daniel;
Fee, Conan;
Dobson, Renwick C. J.;
Nock, Volker

Publication type:

Article

The purification, crystallization and preliminary X-ray diffraction analysis of two isoforms of meso-diaminopimelate decarboxylase from Arabidopsis thaliana.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 5, p. 663, doi. 10.1107/S2053230X14007699

By:

Oliver, Michael R.;
Crowther, Jennifer M.;
Leeman, Mary M.;
Kessans, Sarah A.;
North, Rachel A.;
Donovan, Katherine A.;
Griffin, Michael D. W.;
Suzuki, Hironori;
Hudson, André O.;
Kasanmascheff, Müge;
Dobson, Renwick C. J.

Publication type:

Article

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of N-acetylmannosamine-6-phosphate 2-epimerase from methicillin-resistant Staphylococcus aureus.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 5, p. 650, doi. 10.1107/S2053230X14007171

By:

North, Rachel A.;
Kessans, Sarah A.;
Griffin, Michael D. W.;
Watson, Andrew J. A.;
Fairbanks, Antony J.;
Dobson, Renwick C. J.

Publication type:

Article

Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of N-acetylmannosamine kinase from methicillin-resistant Staphylococcus aureus.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 5, p. 643, doi. 10.1107/S2053230X14007250

By:

North, Rachel A.;
Seizova, Simona;
Stampfli, Anja;
Kessans, Sarah A.;
Suzuki, Hironori;
Griffin, Michael D. W.;
Kvansakul, Marc;
Dobson, Renwick C. J.

Publication type:

Article

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06186-1

By:

Foglizzo, Martina;
Middleton, Adam J.;
Burgess, Abigail E.;
Crowther, Jennifer M.;
Dobson, Renwick C. J.;
Murphy, James M.;
Day, Catherine L.;
Mace, Peter D.

Publication type:

Article

Substrate-bound outward-open structure of a Na+- coupled sialic acid symporter reveals a new Na+ site.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04045-7

By:

Wahlgren, Weixiao Y.;
Dunevall, Elin;
North, Rachel A.;
Paz, Aviv;
Scalise, Mariafrancesca;
Bisignano, Paola;
Bengtsson-Palme, Johan;
Goyal, Parveen;
Claesson, Elin;
Caing-Carlsson, Rhawnie;
Andersson, Rebecka;
Beis, Konstantinos;
Nilsson, Ulf J.;
Farewell, Anne;
Pochini, Lorena;
Indiveri, Cesare;
Grabe, Michael;
Dobson, Renwick C. J.;
Abramson, Jeff;
Ramaswamy, S.

Publication type:

Article

On the function of TRAP substrate-binding proteins: the isethionate-specific binding protein IseP.

Published in:

Biochemical Journal, 2024, v. 481, n. 24, p. 1901, doi. 10.1042/BCJ20240540

By:

Newton-Vesty, Michael C.;
Currie, Michael J.;
Davies, James S.;
Panjikar, Santosh;
Sethi, Ashish;
Whitten, Andrew E.;
Tillett, Zachary D.;
Wood, David M.;
Wright, Joshua D.;
Love, Michael J.;
Allison, Timothy M.;
Jamieson, Sam A.;
Mace, Peter D.;
North, Rachel A.;
Dobson, Renwick C. J.

Publication type:

Article

The structure and function of modular Escherichia coli O157:H7 bacteriophage FTBEc1 endolysin, LysT84: defining a new endolysin catalytic subfamily.

Published in:

Biochemical Journal, 2022, v. 479, n. 2, p. 207, doi. 10.1042/BCJ20210701

By:

Love, Michael J.;
Coombes, David;
Ismail, Salim;
Billington, Craig;
Dobson, Renwick C. J.

Publication type:

Article

The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.

Published in:

Biochemical Journal, 2016, v. 473, n. 12, p. 1733, doi. 10.1042/BCJ20160189

By:

Kelan Chen;
Dobson, Renwick C. J.;
Lucet, Isabelle S.;
Young, Samuel N.;
Pearce, F. Grant;
Blewitt, Marnie E.;
Murphy, James M.

Publication type:

Article

Exploring the structure of glutamate racemase from Mycobacterium tuberculosis as a template for anti-mycobacterial drug discovery.

Published in:

Biochemical Journal, 2016, v. 473, n. 9, p. 1267, doi. 10.1042/BCJ20160186

By:

Poen, Sinothai;
Nakatani, Yoshio;
Opel-Reading, Helen K.;
Lassé, Moritz;
Dobson, Renwick C. J.;
Krause, Kurt L.

Publication type:

Article

Grappling with anisotropic data, pseudo-merohedral twinning and pseudo-translational noncrystallographic symmetry: a case study involving pyruvate kinase.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2016, v. 72, n. 4, p. 512, doi. 10.1107/S205979831600142X

By:

Donovan, Katherine A.;
Atkinson, Sarah C.;
Kessans, Sarah A.;
Peng, Fen;
Cooper, Tim F.;
Griffin, Michael D. W.;
Jameson, Geoffrey B.;
Dobson, Renwick C. J.

Publication type:

Article

On the utility of microfluidic systems to study protein interactions: advantages, challenges, and applications.

Published in:

European Biophysics Journal, 2023, v. 52, n. 4/5, p. 459, doi. 10.1007/s00249-022-01626-9

By:

Watkin, Serena A. J.;
Bennie, Rachel Z.;
Gilkes, Jenna M.;
Nock, Volker M.;
Pearce, F. Grant;
Dobson, Renwick C. J.

Publication type:

Article

Analytical ultracentrifugation: still the gold standard that offers multiple solutions.

Published in:

2020

By:

Dobson, Renwick C. J.;
Patel, Trushar R.

Publication type:

Editorial

Multi-wavelength analytical ultracentrifugation as a tool to characterise protein–DNA interactions in solution.

Published in:

European Biophysics Journal, 2020, v. 49, n. 8, p. 819, doi. 10.1007/s00249-020-01481-6

By:

Horne, Christopher R.;
Henrickson, Amy;
Demeler, Borries;
Dobson, Renwick C. J.

Publication type:

Article

On the utility of fluorescence-detection analytical ultracentrifugation in probing biomolecular interactions in complex solutions: a case study in milk.

Published in:

European Biophysics Journal, 2020, v. 49, n. 8, p. 677, doi. 10.1007/s00249-020-01468-3

By:

Crowther, Jennifer M.;
Broadhurst, Marita;
Laue, Thomas M.;
Jameson, Geoffrey B.;
Hodgkinson, Alison J.;
Dobson, Renwick C. J.

Publication type:

Article

The lid domain is important, but not essential, for catalysis of Escherichia coli pyruvate kinase.

Published in:

European Biophysics Journal, 2020, v. 49, n. 8, p. 761, doi. 10.1007/s00249-020-01466-5

By:

Sugrue, Elena;
Coombes, David;
Wood, David;
Zhu, Tong;
Donovan, Katherine A.;
Dobson, Renwick C. J.

Publication type:

Article

The self-association and thermal denaturation of caprine and bovine β-lactoglobulin.

Published in:

European Biophysics Journal, 2018, v. 47, n. 7, p. 739, doi. 10.1007/s00249-018-1300-8

By:

Crowther, Jennifer M.;
Allison, Jane R.;
Smolenski, Grant A.;
Hodgkinson, Alison J.;
Jameson, Geoffrey B.;
Dobson, Renwick C. J.

Publication type:

Article

Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22253-6

By:

Horne, Christopher R.;
Venugopal, Hariprasad;
Panjikar, Santosh;
Wood, David M.;
Henrickson, Amy;
Brookes, Emre;
North, Rachel A.;
Murphy, James M.;
Friemann, Rosmarie;
Griffin, Michael D. W.;
Ramm, Georg;
Demeler, Borries;
Dobson, Renwick C. J.

Publication type:

Article

Structure-based mechanism of preferential complex formation by apoptosis signal–regulating kinases.

Published in:

Science Signaling, 2020, v. 13, n. 622, p. 1, doi. 10.1126/scisignal.aay6318

By:

Trevelyan, Sarah J.;
Brewster, Jodi L.;
Burgess, Abigail E.;
Crowther, Jennifer M.;
Cadell, Antonia L.;
Parker, Benjamin L.;
Croucher, David R.;
Dobson, Renwick C. J.;
Murphy, James M.;
Mace, Peter D.

Publication type:

Article

Biochemical Characterization of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: meso-2,6-diaminopimelate ligase (MurE) from Verrucomicrobium spinosum DSM 4136T.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066458

By:

McGroty, Sean E.;
Pattaniyil, Dhivya T.;
Patin, Delphine;
Blanot, Didier;
Ravichandran, Arvind C.;
Suzuki, Hironori;
Dobson, Renwick C. J.;
Savka, Michael A.;
Hudson, André O.

Publication type:

Article

Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040318

By:

Griffin, Michael D. W.;
Billakanti, Jagan M.;
Wason, Akshita;
Keller, Sabrina;
Mertens, Haydyn D. T.;
Atkinson, Sarah C.;
Dobson, Renwick C. J.;
Perugini, Matthew A.;
Gerrard, Juliet A.;
Grant Pearce, Frederick

Publication type:

Article

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038318

By:

Atkinson, Sarah C.;
Dogovski, Con;
Downton, Matthew T.;
Pearce, F. Grant;
Reboul, Cyril F.;
Buckle, Ashley M.;
Gerrard, Juliet A.;
Dobson, Renwick C. J.;
Wagner, John;
Perugini, Matthew A.

Publication type:

Article

L,L-Diaminopimelate Aminotransferase from Chlamydomonas reinhardtii: A Target for Algaecide Development.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0020439

By:

Dobson, Renwick C. J.;
Girón, Irma;
Hudson, André O.

Publication type:

Article

Avoidance of stochastic RNA interactions can be harnessed to control protein expression levels in bacteria and archaea.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.13479

By:

Umu, Sinan Uğur;
Poole, Anthony M.;
Dobson, Renwick C. J.;
Gardner, Paul P.

Publication type:

Article

Bacteriophage-encoded lethal membrane disruptors: Advances in understanding and potential applications.

Published in:

Frontiers in Microbiology, 2022, v. 13, p. 1, doi. 10.3389/fmicb.2022.1044143

By:

Abeysekera, Gayan S.;
Love, Michael J.;
Manners, Sarah H.;
Billington, Craig;
Dobson, Renwick C. J.

Publication type:

Article

Using cryo-EM to uncover mechanisms of bacterial transcriptional regulation.

Published in:

Biochemical Society Transactions, 2021, v. 49, n. 6, p. 2711, doi. 10.1042/BST20210674

By:

Wood, David M.;
Dobson, Renwick C. J.;
Horne, Christopher R.

Publication type:

Article

The fitness challenge of studying molecular adaptation.

Published in:

Biochemical Society Transactions, 2019, v. 47, n. 5, p. 1533, doi. 10.1042/BST20180626

By:

Coombes, David;
Moir, James W. B.;
Poole, Anthony M.;
Cooper, Tim F.;
Dobson, Renwick C. J.

Publication type:

Article

Structural and biophysical characterisation of ubiquitin variants that inhibit the ubiquitin conjugating enzyme Ube2d2.

Published in:

FEBS Journal, 2024, v. 291, n. 23, p. 5305, doi. 10.1111/febs.17311

By:

McAlpine, Jeffery M. R. B.;
Zhu, Jingyi;
Pudjihartono, Nicholas;
Teyra, Joan;
Currie, Michael J.;
Tillett, Zachary D.;
Dobson, Renwick C. J.;
Sidhu, Sachdev S.;
Day, Catherine L.;
Middleton, Adam J.

Publication type:

Article