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Vismodegib.
- Published in:
- Nature Reviews Drug Discovery, 2012, v. 11, n. 6, p. 437, doi. 10.1038/nrd3753
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- Article
Harnessing Hedgehog for the Treatment of Basal Cell Carcinoma.
- Published in:
- JAMA Dermatology, 2013, v. 149, n. 5, p. 607, doi. 10.1001/jamadermatol.2013.448
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- Publication type:
- Article
A method for the immortalization of newborn mouse skin keratinocytes.
- Published in:
- Frontiers in Oncology, 2015, p. 1, doi. 10.3389/fonc.2015.00177
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- Publication type:
- Article
Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells.
- Published in:
- EMBO Molecular Medicine, 2012, v. 4, n. 3, p. 218, doi. 10.1002/emmm.201100201
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- Publication type:
- Article
Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.
- Published in:
- 2011
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- Publication type:
- journal article
Dual and opposing roles of primary cilia in medulloblastoma development.
- Published in:
- Nature Medicine, 2009, v. 15, n. 9, p. 1062, doi. 10.1038/nm.2020
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- Publication type:
- Article
Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis.
- Published in:
- Nature Medicine, 2009, v. 15, n. 9, p. 1055, doi. 10.1038/nm.2011
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- Publication type:
- Article
Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin.
- Published in:
- Nature Genetics, 2010, v. 42, n. 10, p. 910, doi. 10.1038/ng.665
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- Publication type:
- Article
Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling.
- Published in:
- Nature Genetics, 2008, v. 40, n. 9, p. 1130, doi. 10.1038/ng.192
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- Publication type:
- Article
Wnt-β-catenin signaling initiates taste papilla development.
- Published in:
- Nature Genetics, 2007, v. 39, n. 1, p. 106, doi. 10.1038/ng1932
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- Publication type:
- Article
Basal cell carcinomas in mice overexpressing Gli2 in skin.
- Published in:
- Nature Genetics, 2000, v. 24, n. 3, p. 216, doi. 10.1038/73417
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- Publication type:
- Article
Inflammation and Gli2 Suppress Gastrin Gene Expression in a Murine Model of Antral Hyperplasia.
- Published in:
- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0048039
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- Publication type:
- Article
Staurosporine induces a complete program of terminal differentiation in neoplastic mouse keratinocytes via activation of protein kinase C.
- Published in:
- Carcinogenesis, 1996, v. 17, n. 6, p. 1259, doi. 10.1093/carcin/17.6.1259
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- Publication type:
- Article
Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis.
- Published in:
- 2016
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- Publication type:
- journal article
Constitutive Hedgehog/GLI2 signaling drives extracutaneous basaloid squamous cell carcinoma development and bone remodeling.
- Published in:
- Carcinogenesis, 2021, v. 42, n. 8, p. 1100, doi. 10.1093/carcin/bgab050
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- Publication type:
- Article
Merkel Cell Polyomavirus Small T Antigen Is Oncogenic in Transgenic Mice.
- Published in:
- Journal of Investigative Dermatology, 2015, v. 135, n. 5, p. 1415, doi. 10.1038/jid.2014.446
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- Publication type:
- Article
Basal Cell Carcinoma, Hedgehog Signaling, and Targeted Therapeutics: The Long and Winding Road.
- Published in:
- Journal of Investigative Dermatology, 2014, v. 134, n. 10, p. E18, doi. 10.1038/skinbio.2014.4
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- Publication type:
- Article
Merkel Cell Carcinoma Dependence on Bcl-2 Family Members for Survival.
- Published in:
- Journal of Investigative Dermatology, 2014, v. 134, n. 8, p. 2241, doi. 10.1038/jid.2014.138
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- Publication type:
- Article
Distinct Gene Expression Profiles of Viral- and Nonviral-Associated Merkel Cell Carcinoma Revealed by Transcriptome Analysis.
- Published in:
- Journal of Investigative Dermatology, 2013, v. 133, n. 4, p. 936, doi. 10.1038/jid.2012.445
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- Publication type:
- Article
Montagna Symposium 2011: 60th Anniversary-Advances in Science and Medicine Catalyzed by Pioneering Skin Research.
- Published in:
- Journal of Investigative Dermatology, 2012, v. 132, n. 5, p. 1317, doi. 10.1038/jid.2011.480
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- Publication type:
- Article
Huntingtin-Interacting Protein 1: A Merkel Cell Carcinoma Marker that Interacts with c-Kit.
- Published in:
- Journal of Investigative Dermatology, 2011, v. 131, n. 10, p. 2113, doi. 10.1038/jid.2011.171
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- Publication type:
- Article
Lack of Evidence for Activation of the Hedgehog Pathway in Psoriasis.
- Published in:
- Journal of Investigative Dermatology, 2009, v. 129, n. 3, p. 635, doi. 10.1038/jid.2008.266
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- Publication type:
- Article
Progress in Cutaneous Cancer Research.
- Published in:
- Journal of Investigative Dermatology, 2002, v. 119, p. 17
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- Publication type:
- Article
Differentiation of Cultured Human Epidermal Keratinocytes at High Cell Densities is Mediated by Endogenous Activation of the Protein Kinase C Signaling Pathway.
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- Journal of Investigative Dermatology, 1998, v. 111, n. 5, p. 762, doi. 10.1046/j.1523-1747.1998.00365.x
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- Publication type:
- Article
Sonic hedgehog processing by pepsin A is altered in human gastric cancer.
- Published in:
- FASEB Journal, 2007, v. 21, n. 6, p. A1321, doi. 10.1096/fasebj.21.6.a1321-b
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- Publication type:
- Article
Definition by specific antisense oligonucleotides of a role for protein kinase Cα in expression of differentiation markers in normal and neoplastic mouse epidermal keratinocytes.
- Published in:
- Molecular Carcinogenesis, 1997, v. 18, n. 1, p. 44, doi. 10.1002/(SICI)1098-2744(199701)18:1<44::AID-MC6>3.0.CO;2-R
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- Publication type:
- Article
Transcripts encoding protein kinase C-α, -ϵ, -ζ, and -ζ are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells.
- Published in:
- Molecular Carcinogenesis, 1992, v. 5, n. 4, p. 286, doi. 10.1002/mc.2940050409
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- Publication type:
- Article
Unique lingual expression of the Hedgehog pathway antagonist Hedgehog‐interacting protein in filiform papillae during homeostasis and ectopic expression in fungiform papillae during Hedgehog signaling inhibition.
- Published in:
- Developmental Dynamics, 2022, v. 251, n. 7, p. 1175, doi. 10.1002/dvdy.456
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- Publication type:
- Article
Staurosporine Induces a Sequential Program of Mouse Keratinocyte Terminal Differentiation through Activation of PKC Isozymes.
- Published in:
- Journal of Investigative Dermatology, 1996, v. 106, n. 3, p. 482, doi. 10.1111/1523-1747.ep12343690
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- Publication type:
- Article
Role of Oncogenes and Tumor Suppressor Genes in Multistage Carcinogenesis.
- Published in:
- Journal of Investigative Dermatology, 1994, v. 103, p. 90S, doi. 10.1038/jid.1994.16
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- Publication type:
- Article
Protein Kinase C Regulates Keratinocyte Transglutaminase (TG<sub>K</sub>) Gene Expression in Cultured Primary Mouse Epidermal Keratinocytes Induced to Terminally Differentiate by Calcium.
- Published in:
- Journal of Investigative Dermatology, 1994, v. 102, n. 4, p. 409, doi. 10.1111/1523-1747.ep12372171
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- Publication type:
- Article
Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1.
- Published in:
- Human Molecular Genetics, 2007, v. 16, n. 11, p. 1279, doi. 10.1093/hmg/ddm076
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- Publication type:
- Article
Loss of functional ELOVL4 depletes very long-chain fatty acids (≥C28) and the unique ω-O-acylceramides in skin leading to neonatal death.
- Published in:
- Human Molecular Genetics, 2007, v. 16, n. 5, p. 471, doi. 10.1093/hmg/ddl480
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- Publication type:
- Article
A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2.
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- Human Molecular Genetics, 2005, v. 14, n. 15, p. 2181, doi. 10.1093/hmg/ddi222
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- Publication type:
- Article
Requirement of the forkhead gene Foxe1, a target of sonic hedgehog signaling, in hair follicle morphogenesis.
- Published in:
- Human Molecular Genetics, 2004, v. 13, n. 21, p. 2595, doi. 10.1093/hmg/ddh292
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- Publication type:
- Article
Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.
- Published in:
- PLoS Genetics, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.pgen.1006442
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- Publication type:
- Article