Works by Dixon, Matthew W. A.

Results: 33

Disruption of Plasmodium falciparum kinetochore proteins destabilises the nexus between the centrosome equivalent and the mitotic apparatus.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50167-6

By:

Li, Jiahong;
Shami, Gerald J.;
Liffner, Benjamin;
Cho, Ellie;
Braet, Filip;
Duraisingh, Manoj T.;
Absalon, Sabrina;
Dixon, Matthew W. A.;
Tilley, Leann

Publication type:

Article

Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum.

Published in:

BMC Biology, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1741-7007-11-67

By:

MacRae, James I.;
Dixon, Matthew W. A.;
Dearnley, Megan K.;
Chua, Hwa H.;
Chambers, Jennifer M.;
Kenny, Shannon;
Bottova, Iveta;
Tilley, Leann;
McConville, Malcolm J.

Publication type:

Article

Deletion of the Plasmodium falciparum exported protein PTP7 leads to Maurer's clefts vesiculation, host cell remodeling defects, and loss of surface presentation of EMP1.

Published in:

PLoS Pathogens, 2022, v. 18, n. 8, p. 1, doi. 10.1371/journal.ppat.1009882

By:

Carmo, Olivia M. S.;
Shami, Gerald J.;
Cox, Dezerae;
Liu, Boyin;
Blanch, Adam J.;
Tiash, Snigdha;
Tilley, Leann;
Dixon, Matthew W. A.

Publication type:

Article

Red Blood Cells Polarize Green Laser Light Revealing Hemoglobin′s Enhanced Non-Fundamental Raman Modes.

Published in:

ChemPhysChem, 2014, v. 15, n. 18, p. 3963, doi. 10.1002/cphc.201402598

By:

Marzec, Katarzyna M.;
Perez‐Guaita, David;
de Veij, Marleen;
McNaughton, Don;
Baranska, Malgorzata;
Dixon, Matthew W. A.;
Tilley, Leann;
Wood, Bayden R.

Publication type:

Article

Inside Cover: Red Blood Cells Polarize Green Laser Light Revealing Hemoglobin′s Enhanced Non-Fundamental Raman Modes (ChemPhysChem 18/2014).

Published in:

ChemPhysChem, 2014, v. 15, n. 18, p. 3882, doi. 10.1002/cphc.201490090

By:

Marzec, Katarzyna M.;
Perez‐Guaita, David;
de Veij, Marleen;
McNaughton, Don;
Baranska, Malgorzata;
Dixon, Matthew W. A.;
Tilley, Leann;
Wood, Bayden R.

Publication type:

Article

The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts Molly.

Published in:

Frontiers in Cellular & Infection Microbiology, 2023, p. 1, doi. 10.3389/fcimb.2023.1211613

By:

Schneider, Molly Parkyn;
Looker, Oliver;
Rebelo, Maria;
Khoury, David S.;
Dixon, Matthew W. A.;
Oeuvray, Claude;
Crabb, Brendan S.;
McCarthy, James;
Gilson, Paul R.

Publication type:

Article

Ankyrin-1 Gene Exhibits Allelic Heterogeneity in Conferring Protection Against Malaria.

Published in:

G3: Genes | Genomes | Genetics, 2017, v. 7, n. 9, p. 3133, doi. 10.1534/g3.117.300079

By:

Hong Ming Huang;
Bauer, Denis C.;
Lelliott, Patrick M.;
Dixon, Matthew W. A.;
Tilley, Leann;
McMorran, Brendan J.;
Foote, Simon J.;
Burgio, Gaetan

Publication type:

Article

Contrasting Inducible Knockdown of the Auxiliary PTEX Component PTEX88 in P. falciparum and P. berghei Unmasks a Role in Parasite Virulence.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0149296

By:

Chisholm, Scott A.;
McHugh, Emma;
Lundie, Rachel;
Dixon, Matthew W. A.;
Ghosh, Sreejoyee;
O’Keefe, Meredith;
Tilley, Leann;
Kalanon, Ming;
de Koning-Ward, Tania F.

Publication type:

Article

Safety, infectivity and immunogenicity of a genetically attenuated blood-stage malaria vaccine.

Published in:

2021

By:

Webster, Rebecca;
Sekuloski, Silvana;
Odedra, Anand;
Woolley, Stephen;
Jennings, Helen;
Amante, Fiona;
Trenholme, Katharine R.;
Healer, Julie;
Cowman, Alan F.;
Eriksson, Emily M.;
Sathe, Priyanka;
Penington, Jocelyn;
Blanch, Adam J.;
Dixon, Matthew W. A.;
Tilley, Leann;
Duffy, Michael F.;
Craig, Alister;
Storm, Janet;
Chan, Jo-Anne;
Evans, Krystal

Publication type:

journal article

Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development.

Published in:

PLoS Pathogens, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.ppat.1006659

By:

Parkyn Schneider, Molly;
Liu, Boyin;
Glock, Philipp;
Suttie, Annika;
McHugh, Emma;
Andrew, Dean;
Batinovic, Steven;
Williamson, Nicholas;
Hanssen, Eric;
McMillan, Paul;
Hliscs, Marion;
Tilley, Leann;
Dixon, Matthew W. A.

Publication type:

Article

Cell biological analysis reveals an essential role for Pfcerli2 in erythrocyte invasion by malaria parasites.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03020-9

By:

Liffner, Benjamin;
Balbin, Juan Miguel;
Shami, Gerald J.;
Siddiqui, Ghizal;
Strauss, Jan;
Frölich, Sonja;
Heinemann, Gary K.;
Edwards, Ella May;
Alder, Arne;
Wichers, Jan Stephan;
Creek, Darren J.;
Tilley, Leann;
Dixon, Matthew W. A.;
Gilberger, Tim-Wolf;
Wilson, Danny W.

Publication type:

Article

Targeting of the Ring Exported Protein 1 to the Maurer’s Clefts is Mediated by a Two-Phase Process.

Published in:

Traffic, 2008, v. 9, n. 8, p. 1316, doi. 10.1111/j.1600-0854.2008.00768.x

By:

Dixon, Matthew W. A.;
Hawthorne, Paula L.;
Spielmann, Tobias;
Anderson, Karen L.;
Trenholme, Katharine R.;
Gardiner, Donald L.

Publication type:

Article

Repurposing the mitotic machinery to drive cellular elongation and chromatin reorganisation in Plasmodium falciparum gametocytes.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32579-4

By:

Li, Jiahong;
Shami, Gerald J.;
Cho, Ellie;
Liu, Boyin;
Hanssen, Eric;
Dixon, Matthew W. A.;
Tilley, Leann

Publication type:

Article

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0181656

By:

Charnaud, Sarah C.;
Dixon, Matthew W. A.;
Nie, Catherine Q.;
Chappell, Lia;
Sanders, Paul R.;
Nebl, Thomas;
Hanssen, Eric;
Berriman, Matthew;
Chan, Jo-Anne;
Blanch, Adam J.;
Beeson, James G.;
Rayner, Julian C.;
Przyborski, Jude M.;
Tilley, Leann;
Crabb, Brendan S.;
Gilson, Paul R.

Publication type:

Article

The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly.

Published in:

PLoS Pathogens, 2019, v. 15, n. 5, p. 1, doi. 10.1371/journal.ppat.1007761

By:

Looker, Oliver;
Blanch, Adam J.;
Liu, Boyin;
Nunez-Iglesias, Juan;
McMillan, Paul J.;
Tilley, Leann;
Dixon, Matthew W. A.

Publication type:

Article

Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells.

Published in:

PLoS Pathogens, 2019, v. 15, n. 2, p. 1, doi. 10.1371/journal.ppat.1007599

By:

Akter, Jasmin;
Khoury, David S.;
Aogo, Rosemary;
Lansink, Lianne I. M.;
SheelaNair, Arya;
Thomas, Bryce S.;
Laohamonthonkul, Pawat;
Pernold, Clara P. S.;
Dixon, Matthew W. A.;
Soon, Megan S. F.;
Fogg, Lily G.;
Engel, Jessica A.;
Elliott, Trish;
Sebina, Ismail;
James, Kylie R.;
Cromer, Deborah;
Davenport, Miles P.;
Haque, Ashraful

Publication type:

Article

Specific expression and export of the Plasmodium falciparum Gametocyte Exported Protein-5 marks the gametocyte ring stage.

Published in:

Malaria Journal, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12936-015-0853-6

By:

Tibúrcio, Marta;
Dixon, Matthew W. A.;
Looker, Oliver;
Younis Younis, Sumera;
Tilley, Leann;
Alano, Pietro

Publication type:

Article

Temporal evaluation of commitment to sexual development in Plasmodium falciparum.

Published in:

Malaria Journal, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2875-12-134

By:

Peatey, Christopher L.;
Dixon, Matthew W. A.;
Gardiner, Donald L.;
Trenholme, Katharine R.

Publication type:

Article

A repeat sequence domain of the ring-exported protein-1 of Plasmodium falciparum controls export machinery architecture and virulence protein trafficking.

Published in:

Molecular Microbiology, 2015, v. 98, n. 6, p. 1101, doi. 10.1111/mmi.13201

By:

McHugh, Emma;
Batinovic, Steven;
Hanssen, Eric;
McMillan, Paul J.;
Kenny, Shannon;
Griffin, Michael D. W.;
Crawford, Simon;
Trenholme, Katharine R.;
Gardiner, Donald L.;
Dixon, Matthew W. A.;
Tilley, Leann

Publication type:

Article

The Plasmodium translocon of exported proteins ( PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth.

Published in:

Molecular Microbiology, 2013, v. 89, n. 6, p. 1167, doi. 10.1111/mmi.12334

By:

Matthews, Kathryn;
Kalanon, Ming;
Chisholm, Scott A.;
Sturm, Angelika;
Goodman, Christopher D.;
Dixon, Matthew W. A.;
Sanders, Paul R.;
Nebl, Thomas;
Fraser, Fiona;
Haase, Silvia;
McFadden, Geoffrey I.;
Gilson, Paul R.;
Crabb, Brendan S.;
Koning‐Ward, Tania F.

Publication type:

Article

Genetic ablation of a Maurer's cleft protein prevents assembly of the Plasmodium falciparum virulence complex.

Published in:

Molecular Microbiology, 2011, v. 81, n. 4, p. 982, doi. 10.1111/j.1365-2958.2011.07740.x

By:

Dixon, Matthew W. A.;
Kenny, Shannon;
McMillan, Paul J.;
Hanssen, Eric;
Trenholme, Katharine R.;
Gardiner, Donald L.;
Tilley, Leann

Publication type:

Article

Targeted mutagenesis of the ring-exported protein-1 of Plasmodium falciparum disrupts the architecture of Maurer's cleft organelles.

Published in:

Molecular Microbiology, 2008, v. 69, n. 4, p. 938, doi. 10.1111/j.1365-2958.2008.06329.x

By:

Hanssen, Eric;
Hawthorne, Paula;
Dixon, Matthew W. A.;
Trenholme, Katharine R.;
McMillan, Paul J.;
Spielmann, Tobias;
Gardiner, Donald L.;
Tilley, Leann

Publication type:

Article

An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytes.

Published in:

Nature Communications, 2017, v. 8, n. 7, p. 16044, doi. 10.1038/ncomms16044

By:

Batinovic, Steven;
McHugh, Emma;
Chisholm, Scott A.;
Matthews, Kathryn;
Liu, Boiyin;
Dumont, Laure;
Charnaud, Sarah C.;
Schneider, Molly Parkyn;
Gilson, Paul R.;
de Koning-Ward, Tania F.;
Dixon, Matthew W. A.;
Tilley, Leann

Publication type:

Article

A female gametocyte-specific ABC transporter plays a role in lipid metabolism in the malaria parasite.

Published in:

Nature Communications, 2014, v. 5, n. 9, p. 4773, doi. 10.1038/ncomms5773

By:

Tran, Phuong N.;
Brown, Simon H. J.;
Mitchell, Todd W.;
Matuschewski, Kai;
McMillan, Paul J.;
Kirk, Kiaran;
Dixon, Matthew W. A.;
Maier, Alexander G.

Publication type:

Article

A new Python library to analyse skeleton images confirms malaria parasite remodelling of the red blood cell membrane skeleton.

Published in:

PeerJ, 2018, p. 1, doi. 10.7717/peerj.4312

By:

Nunez-Iglesias, Juan;
Blanch, Adam J.;
Looker, Oliver;
Dixon, Matthew W.;
Tilley, Leann

Publication type:

Article

Surface area‐to‐volume ratio, not cellular viscoelasticity, is the major determinant of red blood cell traversal through small channels.

Published in:

Cellular Microbiology, 2021, v. 23, n. 1, p. 1, doi. 10.1111/cmi.13270

By:

Namvar, Arman;
Blanch, Adam J.;
Dixon, Matthew W.;
Carmo, Olivia M. S.;
Liu, Boyin;
Tiash, Snigdha;
Looker, Oliver;
Andrew, Dean;
Chan, Li‐Jin;
Tham, Wai‐Hong;
Lee, Peter V. S.;
Rajagopal, Vijay;
Tilley, Leann

Publication type:

Article

Organization and function of an actin cytoskeleton in P lasmodium falciparum gametocytes.

Published in:

Cellular Microbiology, 2015, v. 17, n. 2, p. 207, doi. 10.1111/cmi.12359

By:

Hliscs, Marion;
Millet, Coralie;
Dixon, Matthew W.;
Siden‐Kiamos, Inga;
McMillan, Paul;
Tilley, Leann

Publication type:

Article

Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum.

Published in:

Cellular Microbiology, 2013, v. 15, n. 8, p. 1401, doi. 10.1111/cmi.12125

By:

McMillan, Paul J.;
Millet, Coralie;
Batinovic, Steven;
Maiorca, Mauro;
Hanssen, Eric;
Kenny, Shannon;
Muhle, Rebecca A.;
Melcher, Martin;
Fidock, David A.;
Smith, Joseph D.;
Dixon, Matthew W. A.;
Tilley, Leann

Publication type:

Article

Initiation of gametocytogenesis at very low parasite density in Plasmodium falciparum infection.

Published in:

2017

By:

Farid, Ryan;
Dixon, Matthew W.;
Tilley, Leann;
McCarthy, James S.

Publication type:

journal article

Nanobodies against Pfs230 block Plasmodium falciparum transmission.

Published in:

Biochemical Journal, 2022, v. 479, n. 24, p. 2529, doi. 10.1042/BCJ20220554

By:

Dietrich, Melanie H.;
Gabriela, Mikha;
Reaksudsan, Kitsanapong;
Dixon, Matthew W. A.;
Li-Jin Chan;
Adair, Amy;
Trickey, Stephanie;
O'Neill, Matthew T.;
Li Lynn Tan;
Lopaticki, Sash;
Healer, Julie;
Keremane, Sravya;
Cowman, Alan F.;
Wai-Hong Tham

Publication type:

Article

PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytes.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15127-w

By:

Liffner, Benjamin;
Frölich, Sonja;
Heinemann, Gary K.;
Liu, Boyin;
Ralph, Stuart A.;
Dixon, Matthew W. A.;
Gilberger, Tim-Wolf;
Wilson, Danny W.

Publication type:

Article

Plasmodium falciparum formins are essential for invasion and sexual stage development.

Published in:

Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05233-y

By:

Collier, Sophie;
Pietsch, Emma;
Dans, Madeline;
Ling, Dawson;
Tavella, Tatyana A.;
Lopaticki, Sash;
Marapana, Danushka S.;
Shibu, Mohini A.;
Andrew, Dean;
Tiash, Snigdha;
McMillan, Paul J.;
Gilson, Paul;
Tilley, Leann;
Dixon, Matthew W. A.

Publication type:

Article

Effect of Antimalarial Drugs on Plasmodium falciparum Gametocytes.

Published in:

Journal of Infectious Diseases, 2009, v. 200, n. 10, p. 1518, doi. 10.1086/644645

By:

Peatey, Christopher L.;
Skinner-Adams, Tina S.;
Dixon, Matthew W. A.;
McCarthy, James S.;
Gardiner, Donald L.;
Trenholme, Katharine R.

Publication type:

Article