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Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 21, p. 3482, doi. 10.3390/cells11213482
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- Publication type:
- Article
Bile Acids Activated Receptors in Inflammatory Bowel Disease.
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- Cells (2073-4409), 2021, v. 10, n. 6, p. 1281, doi. 10.3390/cells10061281
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- Publication type:
- Article
Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity.
- Published in:
- Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00505
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- Publication type:
- Article
Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases.
- Published in:
- Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00162
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- Publication type:
- Article
Activation of the bile acid receptor GPBAR1 protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs and aspirin in mice.
- Published in:
- British Journal of Pharmacology, 2013, v. 168, n. 1, p. 225, doi. 10.1111/j.1476-5381.2012.02128.x
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- Publication type:
- Article
Activation of the farnesoid-X receptor protects against gastrointestinal injury caused by non-steroidal anti-inflammatory drugs in mice.
- Published in:
- 2011
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- Publication type:
- journal article
Discovery of a Novel Multi-Strains Probiotic Formulation with Improved Efficacy toward Intestinal Inflammation.
- Published in:
- Nutrients, 2020, v. 12, n. 7, p. 1945, doi. 10.3390/nu12071945
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- Publication type:
- Article
The Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic Dysfunctions.
- Published in:
- Nutrients, 2019, v. 11, n. 8, p. 1820, doi. 10.3390/nu11081820
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- Publication type:
- Article
Transcriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation.
- Published in:
- Nutrients, 2019, v. 11, n. 5, p. 1, doi. 10.3390/nu11051132
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- Publication type:
- Article
Divergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic Properties.
- Published in:
- Nutrients, 2019, v. 11, n. 2, p. 325, doi. 10.3390/nu11020325
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- Publication type:
- Article
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling.
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- FASEB Journal, 2022, v. 36, n. 1, p. 1, doi. 10.1096/fj.202101397R
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- Publication type:
- Article
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
- Published in:
- FASEB Journal, 2021, v. 35, n. 1, p. 1, doi. 10.1096/fj.202001386R
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- Publication type:
- Article
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis.
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- FASEB Journal, 2019, v. 33, n. 2, p. 2809, doi. 10.1096/fj.201801373RR
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- Publication type:
- Article
Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition.
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- FASEB Journal, 2012, v. 26, n. 7, p. 3021, doi. 10.1096/fj.11-195701
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- Publication type:
- Article
Analysis of Gastric Cancer Transcriptome Allows the Identification of Histotype Specific Molecular Signatures With Prognostic Potential.
- Published in:
- Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.663771
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- Publication type:
- Article
The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer.
- Published in:
- Cellular Oncology (2211-3428), 2024, v. 47, n. 2, p. 695, doi. 10.1007/s13402-023-00893-8
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- Publication type:
- Article
Dissociation of Intestinal and Hepatic Activities of FXR and LXRα Supports Metabolic Effects of Terminal Ileum Interposition in Rodents.
- Published in:
- Diabetes, 2013, v. 62, n. 10, p. 3384, doi. 10.2337/db13-0299
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- Publication type:
- Article
Bile Acids Activated Receptors Regulate Innate Immunity.
- Published in:
- Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01853
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- Publication type:
- Article
Proteinase-activated receptors (PARs) and immune function.
- Published in:
- Drug Development Research, 2003, v. 60, n. 1, p. 65, doi. 10.1002/ddr.10322
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- Publication type:
- Article
Rectal Function and Bowel Habit in Irritable Bowel Syndrome.
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- American Journal of Gastroenterology (Springer Nature), 2004, v. 99, n. 1, p. 131, doi. 10.1046/j.1572-0241.2003.04012.x
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- Publication type:
- Article
Circadian Variations in Gastric Acid and Pepsin Secretion and Intragastric Bile Acid in Patients with Reflux Esophagitis and in Healthy Controls.
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- American Journal of Gastroenterology (Springer Nature), 1995, v. 90, n. 2, p. 270
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- Publication type:
- Article
Effect of Erythromycin on Gastric and Gallbladder Emptying and Gastrointestinal Symptoms in Scleroderma Patients is Maintained Medium Term.
- Published in:
- American Journal of Gastroenterology (Springer Nature), 1994, v. 89, n. 4, p. 550
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- Publication type:
- Article
Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma.
- Published in:
- Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1140730
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- Publication type:
- Article
Inhibition of Intestinal Bacterial Translocation with Rifaximin Modulates Lamina propria Monocytic Cells Reactivity and Protects against Inflammation in a Rodent Model of Colitis.
- Published in:
- Digestion, 2002, v. 66, n. 4, p. 246, doi. 10.1159/000068362
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- Publication type:
- Article
Modulation of Intestinal Microbiota by the Probiotic VSL#3 Resets Brain Gene Expression and Ameliorates the Age-Related Deficit in LTP.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106503
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- Publication type:
- Article
Probiotics VSL#3 Protect against Development of Visceral Pain in Murine Model of Irritable Bowel Syndrome
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- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063893
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- Publication type:
- Article
The Bile Acid Sensor FXR Is Required for Immune-Regulatory Activities of TLR-9 in Intestinal Inflammation.
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- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054472
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- Publication type:
- Article
VSL#3 Resets Insulin Signaling and Protects against NASH and Atherosclerosis in a Model of Genetic Dyslipidemia and Intestinal Inflammation.
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- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045425
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- Publication type:
- Article
The Bile Acid Receptor GPBAR-1 (TGR5) Modulates Integrity of Intestinal Barrier and Immune Response to Experimental Colitis.
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- PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0025637
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- Publication type:
- Article
Probiotics Modulate Intestinal Expression of Nuclear Receptor and Provide Counter-Regulatory Signals to Inflammation-Driven Adipose Tissue Activation.
- Published in:
- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022978
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- Publication type:
- Article
The Bile Acid Sensor FXR Protects against Dyslipidemia and Aortic Plaques Development Induced by the HIV Protease Inhibitor Ritonavir in Mice.
- Published in:
- PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013238
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- Publication type:
- Article
Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis.
- Published in:
- Scientific Reports, 2017, p. 41055, doi. 10.1038/srep41055
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- Publication type:
- Article
Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis.
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- Scientific Reports, 2016, p. 30802, doi. 10.1038/srep30802
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- Publication type:
- Article
Liver delivery of NO by NCX-1000 protects against acute liver failure and mitochondrial dysfunction induced by APAP in mice.
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- British Journal of Pharmacology, 2004, v. 143, n. 1, p. 33, doi. 10.1038/sj.bjp.0705780
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- Publication type:
- Article
Evidence that 5-lipoxygenase and acetylated cycloocygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
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- British Journal of Pharmacology, 2003, v. 139, n. 7, p. 1351, doi. 10.1038/sj.bjp.0705356
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- Publication type:
- Article
Anti-Inflammatory Activity of a New Class of Nitric Oxide Synthase Inhibitors That Release Nitric Oxide.
- Published in:
- ChemMedChem, 2008, v. 3, n. 10, p. 1580, doi. 10.1002/cmdc.200800201
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- Publication type:
- Article
Hydrogen sulphide induces μ opioidreceptor-dependent analgesia in a rodent modelof visceral pain.
- Published in:
- Molecular Pain, 2010, v. 6, n. 1, p. 36, doi. 10.1186/1744-8069-6-36
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- Publication type:
- Article
SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts.
- Published in:
- Inflammation Research, 2011, v. 60, n. 6, p. 577, doi. 10.1007/s00011-010-0306-1
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- Publication type:
- Article
Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28647-4
- By:
- Publication type:
- Article
Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis.
- Published in:
- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.939969
- By:
- Publication type:
- Article
A Hydrogen-Sulfide Releasing Derivative of Mesalamine Exhibits Markedly Enhanced Anti-Inflammatory Effects in Experimental Colitis.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A131, doi. 10.1096/fasebj.21.5.a131-a
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- Publication type:
- Article
Hydrogen sulfide is an endogenous modulator of leukocyte mediated inflammation.
- Published in:
- FASEB Journal, 2006, v. 20, n. 12, p. 2118, doi. 10.1096/fj.06-6270fje
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- Publication type:
- Article
Relative contribution of acetylated cyclooxygenase (COX)‐2 and 5‐lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin.
- Published in:
- FASEB Journal, 2003, v. 17, n. 9, p. 1171, doi. 10.1096/fj.02-0777fje
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- Publication type:
- Article
NCX‐4016, a nitric oxide‐releasing aspirin, protects endothelial cells against apoptosis by modulating mitochondrial function.
- Published in:
- FASEB Journal, 2002, v. 16, n. 12, p. 1645, doi. 10.1096/fj.02-0297fje
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- Publication type:
- Article
Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G-Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease.
- Published in:
- Journal of the American Heart Association, 2023, v. 12, n. 23, p. 1, doi. 10.1161/JAHA.123.031241
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- Publication type:
- Article
Bile acid activated receptors are targets for regulation of integrity of gastrointestinal mucosa.
- Published in:
- Journal of Gastroenterology, 2015, v. 50, n. 7, p. 707, doi. 10.1007/s00535-015-1041-8
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- Publication type:
- Article
Abscess formation in hepatocellular carcinoma: complications of percutaneous ultrasound-guided ethanol injection.
- Published in:
- 1993
- By:
- Publication type:
- journal article
Serum Bile Acid Levels Before and After Sleeve Gastrectomy and Their Correlation with Obesity-Related Comorbidities.
- Published in:
- Obesity Surgery, 2019, v. 29, n. 8, p. 2517, doi. 10.1007/s11695-019-03877-6
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- Publication type:
- Article
Special FX: Harnessing the Farnesoid-X-Receptor to Control Bile Acid Synthesis.
- Published in:
- 2021
- By:
- Publication type:
- Editorial
Bile Acid Signaling in Inflammatory Bowel Diseases.
- Published in:
- Digestive Diseases & Sciences, 2021, v. 66, n. 3, p. 674, doi. 10.1007/s10620-020-06715-3
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- Publication type:
- Article