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Relationship between sex, APOE genotype, endocannabinoids and cognitive change in older adults with metabolic syndrome during a 3-year Mediterranean diet intervention.
- Published in:
- Nutrition Journal, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12937-024-00966-w
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- Article
Lamivudine modulates the expression of neurological impairment-related genes and LINE-1 retrotransposons in brain tissues of a Down syndrome mouse model.
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- Frontiers in Aging Neuroscience, 2024, p. 1, doi. 10.3389/fnagi.2024.1386944
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- Article
Social Factors Influence Behavior in the Novel Object Recognition Task in a Mouse Model of Down Syndrome.
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- Frontiers in Behavioral Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fnbeh.2021.772734
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- Article
Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition.
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- Frontiers in Molecular Neuroscience, 2021, v. 13, p. N.PAG, doi. 10.3389/fnmol.2021.664912
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- Article
Down Syndrome: From Understanding the Neurobiology to Therapy.
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- Journal of Neuroscience, 2010, v. 30, n. 45, p. 14943, doi. 10.1523/JNEUROSCI.3728-10.2010
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- Publication type:
- Article
Dose dependent effects of green tea extracts in the skeletal development of a Down syndrome mouse model.
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- FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4982
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- Publication type:
- Article
Altered Genetic Expression Disrupts Facial Ontogenetic Trajectory in Down Syndrome and DYRK1A Haploinsufficiency.
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- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.03721
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- Publication type:
- Article
AGC1-malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway.
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- Journal of Neurochemistry, 2013, v. 124, n. 3, p. 347, doi. 10.1111/jnc.12096
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- Publication type:
- Article
Genome-wide miR-155 and miR-802 target gene identification in the hippocampus of Ts65Dn Down syndrome mouse model by miRNA sponges.
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- BMC Genomics, 2015, v. 16, p. 1, doi. 10.1186/s12864-015-2160-6
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- Article
Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases.
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- Molecules, 2015, v. 20, n. 3, p. 4655, doi. 10.3390/molecules20034655
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- Article
uPA deficiency exacerbates muscular dystrophy in MDX mice.
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- Journal of Cell Biology, 2007, v. 178, n. 6, p. 1039, doi. 10.1083/jcb.200705127
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- Publication type:
- Article
COVID-19 Vaccination of Individuals with Down Syndrome—Data from the Trisomy 21 Research Society Survey on Safety, Efficacy, and Factors Associated with the Decision to Be Vaccinated.
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- Vaccines, 2022, v. 10, n. 4, p. N.PAG, doi. 10.3390/vaccines10040530
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- Publication type:
- Article
Heterozygous deletion of the Williams–Beuren syndrome critical interval in mice recapitulates most features of the human disorder.
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- Human Molecular Genetics, 2014, v. 23, n. 24, p. 6481, doi. 10.1093/hmg/ddu368
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- Article
A new mouse model for the trisomy of the Abcg1–U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome.
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- Human Molecular Genetics, 2009, v. 18, n. 24, p. 4756, doi. 10.1093/hmg/ddp438
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- Publication type:
- Article
Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders.
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- Human Molecular Genetics, 2008, v. 17, n. 9, p. 1234, doi. 10.1093/hmg/ddn013
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- Publication type:
- Article
DYRK1A Overexpression Alters Cognition and Neural-Related Proteomic Pathways in the Hippocampus That Are Rescued by Green Tea Extract and/or Environmental Enrichment.
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- Frontiers in Molecular Neuroscience, 2019, v. 12, p. N.PAG, doi. 10.3389/fnmol.2019.00272
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- Article
Beyond Quiescent and Active: Intermediate Microglial Transcriptomic States in a Mouse Model of Down Syndrome.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3289, doi. 10.3390/ijms25063289
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- Article
Rethinking Intellectual Disability from Neuro- to Astro-Pathology.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 23, p. 9039, doi. 10.3390/ijms21239039
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- Article
Molecular Rescue of Dyrk1A Overexpression Alterations in Mice with Fontup® Dietary Supplement: Role of Green Tea Catechins.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 4, p. 1404, doi. 10.3390/ijms21041404
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- Article
Meta-analysis of transcriptomic data reveals clusters of consistently deregulated gene and disease ontologies in Down syndrome.
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- PLoS Computational Biology, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.pcbi.1009317
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- Article
Ethanol-Induced Changes in Brain of Transgenic Mice Overexpressing DYRK1A.
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- Molecular Neurobiology, 2020, v. 57, n. 7, p. 3195, doi. 10.1007/s12035-020-01967-6
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- Article
Down syndrome: the brain in trisomic mode.
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- Nature Reviews Neuroscience, 2012, v. 13, n. 12, p. 844, doi. 10.1038/nrn3314
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- Article
Down syndrome: the brain in trisomic mode.
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- 2012
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- Publication type:
- research
Cognition and Hippocampal Plasticity in the Mouse Is Altered by Monosomy of a Genomic Region Implicated in Down Syndrome.
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- Genetics, 2014, v. 197, n. 3, p. 899, doi. 10.1534/genetics.114.165241
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- Article
Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice.
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- Acta Neuropathologica Communications, 2014, v. 2, n. 1, p. 1, doi. 10.1186/s40478-014-0147-1
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- Article
Building the Future Therapies for Down Syndrome: The Third International Conference of the T21 Research Society.
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- Molecular Syndromology, 2021, v. 12, n. 4, p. 202, doi. 10.1159/000514437
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- Article
Paving the Way for Therapy: The Second International Conference of the Trisomy 21 Research Society.
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- Molecular Syndromology, 2018, v. 9, n. 6, p. 279, doi. 10.1159/000494231
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- Publication type:
- Article
Changing Paradigms in Down Syndrome: The First International Conference of the Trisomy 21 Research Society.
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- Molecular Syndromology, 2016, v. 7, n. 5, p. 251, doi. 10.1159/000449049
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- Publication type:
- Article
Metabolomics predicts the pharmacological profile of new psychoactive substances.
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- 2019
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- Publication type:
- journal article
Opposite Phenotypes of Muscle Strength and Locomotor Function in Mouse Models of Partial Trisomy and Monosomy 21 for the Proximal Hspa13-App Region.
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- PLoS Genetics, 2015, v. 11, n. 3, p. 1, doi. 10.1371/journal.pgen.1005062
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- Publication type:
- Article
Modeling the impact of neuromorphological alterations in Down syndrome on fast neural oscillations.
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- PLoS Computational Biology, 2024, v. 20, n. 7, p. 1, doi. 10.1371/journal.pcbi.1012259
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- Publication type:
- Article
Overexpression of Reelin Prevents the Manifestation of Behavioral Phenotypes Related to Schizophrenia and Bipolar Disorder.
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- Neuropsychopharmacology, 2011, v. 36, n. 12, p. 2395, doi. 10.1038/npp.2011.153
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- Publication type:
- Article
Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss.
- Published in:
- eLife, 2018, p. 1, doi. 10.7554/eLife.31511
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- Publication type:
- Article
The Value of Mouse Models of Rare Diseases: A Spanish Experience.
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- Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.583932
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- Article
Reduced Mid1 expression and delayed neuromotor development in daDREAM transgenic mice.
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- Frontiers in Molecular Neuroscience, 2012, p. 1, doi. 10.3389/fnmol.2012.00058
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- Publication type:
- Article
Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.
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- Molecular Nutrition & Food Research, 2014, v. 58, n. 2, p. 278, doi. 10.1002/mnfr.201300325
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- Publication type:
- Article
Overexpression of Dyrk1A, a Down Syndrome Candidate, Decreases Excitability and Impairs Gamma Oscillations in the Prefrontal Cortex.
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- Journal of Neuroscience, 2016, v. 36, n. 13, p. 3648, doi. 10.1523/JNEUROSCI.2517-15.2016
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- Publication type:
- Article
New Perspectives for the Rescue of Cognitive Disability in Down Syndrome.
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- Journal of Neuroscience, 2015, v. 35, n. 41, p. 13843, doi. 10.1523/JNEUROSCI.2775-15.2015
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- Publication type:
- Article
Hippocampal Hyperexcitability Underlies Enhanced Fear Memories in TgNTRK3, a Panic Disorder Mouse Model.
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- Journal of Neuroscience, 2013, v. 33, n. 38, p. 15259, doi. 10.1523/JNEUROSCI.2161-13.2013
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- Publication type:
- Article
Deficits in neuronal architecture but not over-inhibition are main determinants of reduced neuronal network activity in a mouse model of overexpression of Dyrk1A.
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- Cerebral Cortex, 2024, v. 34, n. 1, p. 1, doi. 10.1093/cercor/bhad431
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- Publication type:
- Article
Time-course and dynamics of obesity-related behavioral changes induced by energy-dense foods in mice.
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- 2018
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- Publication type:
- journal article
Extinction and reinstatement of an operant responding maintained by food in different models of obesity.
- Published in:
- 2018
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- Publication type:
- journal article
An animal model of compulsive food-taking behaviour.
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- Addiction Biology, 2009, v. 14, n. 4, p. 373, doi. 10.1111/j.1369-1600.2009.00175.x
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- Publication type:
- Article
NGF Upregulates the Plasminogen Activation Inhibitor-1 in Neurons via the Calcineurin/NFAT Pathway and the Down Syndrome-Related Proteins DYRK1A and RCAN1 Attenuate This Effect.
- Published in:
- PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067470
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- Publication type:
- Article
Dyrk1A Is Dynamically Expressed on Subsets of Motor Neurons and in the Neuromuscular Junction: Possible Role in Down Syndrome.
- Published in:
- PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054285
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- Publication type:
- Article
RhoE Deficiency Produces Postnatal Lethality, Profound Motor Deficits and Neurodevelopmental Delay in Mice.
- Published in:
- PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019236
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- Publication type:
- Article
Behavioral Characterization of a Mouse Model Overexpressing DSCR1/ RCAN1.
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- PLoS ONE, 2011, v. 6, n. 2, p. 1, doi. 10.1371/journal.pone.0017010
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- Publication type:
- Article
Impaired Spatial Learning Strategies and Novel Object Recognition in Mice Haploinsufficient for the Dual Specificity Tyrosine-Regulated Kinase-1A (Dyrk1A).
- Published in:
- PLoS ONE, 2008, v. 3, n. 7, p. 1, doi. 10.1371/journal.pone.0002575
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- Article
Editorial: Brain Insulin Resistance in Neurodevelopmental and Neurodegenerative Disorders: Mind the Gap!
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- 2021
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- Publication type:
- Editorial
RhoE deficiency alters postnatal subventricular zone development and the number of calbindin-expressing neurons in the olfactory bulb of mouse.
- Published in:
- Brain Structure & Function, 2015, v. 220, n. 6, p. 3113, doi. 10.1007/s00429-014-0846-1
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- Publication type:
- Article