Works by Diano, Sabrina

Results: 46

Suppression of endothelial ceramide de novo biosynthesis by Nogo-B contributes to cardiometabolic diseases.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56869-9

By:

Rubinelli, Luisa;
Manzo, Onorina Laura;
Sungho, Jin;
Del Gaudio, Ilaria;
Bareja, Rohan;
Marino, Alice;
Palikhe, Sailesh;
Di Mauro, Vittoria;
Bucci, Mariarosaria;
Falcone, Domenick J.;
Elemento, Olivier;
Ersoy, Baran;
Diano, Sabrina;
Sasset, Linda;
Di Lorenzo, Annarita

Publication type:

Article

Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system.

Published in:

Journal of Comparative Neurology, 1999, v. 415, n. 2, p. 145, doi. 10.1002/(SICI)1096-9861(19991213)415:2<145::AID-CNE1>3.0.CO;2-2

By:

Horvath, Tamas L.;
Peyron, Christelle;
Diano, Sabrina;
Ivanov, Alexander;
Aston-Jones, Gary;
Kilduff, Thomas S.;
van den Pol, Anthony N.

Publication type:

Article

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals.

Published in:

Nature, 2008, v. 454, n. 7206, p. 846, doi. 10.1038/nature07181

By:

Andrews, Zane B.;
Liu, Zhong-Wu;
Walllingford, Nicholas;
Erion, Derek M.;
Borok, Erzsebet;
Friedman, Jeffery M.;
Tschöp, Matthias H.;
Shanabrough, Marya;
Cline, Gary;
Shulman, Gerald I.;
Coppola, Anna;
Gao, Xiao-Bing;
Horvath, Tamas L.;
Diano, Sabrina

Publication type:

Article

A Novel Growth Hormone Secretagogue-1a Receptor Antagonist That Blocks Ghrelin-Induced Growth Hormone Secretion but Induces Increased Body Weight Gain.

Published in:

Neuroendocrinology, 2005, v. 81, n. 5, p. 339, doi. 10.1159/000088796

By:

Halem, Heather A.;
Taylor, John E.;
Dong, Jesse Z.;
Shen, Yeelana;
Datta, Rakesh;
Abizaid, Alfonso;
Diano, Sabrina;
Horvath, Tamas L.;
Culler, Michael D.

Publication type:

Article

Role of Reactive Oxygen Species in Hypothalamic Regulation of Energy Metabolism.

Published in:

Endocrinology & Metabolism, 2013, v. 28, n. 1, p. 3, doi. 10.3803/EnM.2013.28.1.3

By:

Diano, Sabrina

Publication type:

Article

Interaction between the Corticotropin-Releasing Factor System and Hypocretins (Orexins): A Novel Circuit Mediating Stress Response.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 50, p. 11439, doi. 10.1523/JNEUROSCI.3459-04.2004

By:

Winsky-Sommerer, Raphaëlle;
Yamanaka, Akihiro;
Diano, Sabrina;
Roberts, Amanda J.;
Sakurai, Takeshi;
Kilduff, Thomas S.;
Horvath, Tamas L.;
De Lecea, Luis

Publication type:

Article

PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 4017, doi. 10.1172/JCI76220

By:

Lihong Long;
Chitoku Toda;
Jing Kwon Jeong;
Horvath, Tamas L.;
Diano, Sabrina

Publication type:

Article

Prolylcarboxypeptidase regulates food intake by inactivating alpha-MSH in rodents.

Published in:

2009

By:

Wallingford, Nicholas;
Perroud, Bertrand;
Qian Gao;
Coppola, Anna;
Gyengesi, Erika;
Zhong-Wu Liu;
Xiao-Bing Gao;
Diament, Adam;
Haus, Kari A.;
Shariat-Madar, Zia;
Mahdi, Fakhri;
Wardlaw, Sharon L.;
Schmaier, Alvin H.;
Warden, Craig H.;
Diano, Sabrina;
Gao, Qian;
Liu, Zhong-Wu;
Gao, Xiao-Bing

Publication type:

journal article

Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia.

Published in:

2008

By:

Xinmin Xie;
Wisor, Jonathan P.;
Hara, Junko;
Crowder, Tara L.;
LeWinter, Robin;
Khroyan, Taline V.;
Yamanaka, Akihiro;
Diano, Sabrina;
Horvath, Tamas L.;
Sakurai, Takeshi;
Toll, Lawrence;
Kilduff, Thomas S.;
Xie, Xinmin

Publication type:

journal article

Anticonvulsant effects of leptin in epilepsy.

Published in:

2008

By:

Diano, Sabrina;
Horvath, Tamas L.

Publication type:

journal article

Mitochondrial Fission Governed by Drp1 Regulates Exogenous Fatty Acid Usage and Storage in Hela Cells.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 5, p. 322, doi. 10.3390/metabo11050322

By:

Song, Jae-Eun;
Alves, Tiago C.;
Stutz, Bernardo;
Šestan-Peša, Matija;
Kilian, Nicole;
Jin, Sungho;
Diano, Sabrina;
Kibbey, Richard G.;
Horvath, Tamas L.;
Divakaruni, Ajit;
Wallace, Martina

Publication type:

Article

Drp1 is required for AgRP neuronal activity and feeding.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.64351

By:

Sungho Jin;
Nal Ae Yoon;
Zhong-Wu Liu;
Jae Eun Song;
Horvath, Tamas L.;
Jung Dae Kim;
Diano, Sabrina

Publication type:

Article

Agrp NeuronsMediate Sirt1's Action on the Melanocortin System and Energy Balance: Roles for Sirt1 in Neuronal Firing and Synaptic Plasticity.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 35, p. 11815, doi. 10.1523/JNEUROSCI.2234-10.2010

By:

Dietrich, Marcelo O.;
Antunes, Catiele;
Gan Geliang;
Zhong-Wu Liu;
Borok, Erzsebet;
Yongzhan Nie;
Xu, Allison W.;
Souza, Diogo O.;
Qian Gao;
Diano, Sabrina;
Xiao-Bing Gao;
Horvath, Tamas L.

Publication type:

Article

Brain Circuits Regulating Energy Homeostasis.

Published in:

Neuroscientist, 2004, v. 10, n. 3, p. 235, doi. 10.1177/1073858403262151

By:

Horvath, Tamas L.;
Diano, Sabrina;
Tschöp, Matthias

Publication type:

Article

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding.

Published in:

Nature Neuroscience, 2014, v. 17, n. 7, p. 908, doi. 10.1038/nn.3725

By:

Kim, Jae Geun;
Suyama, Shigetomo;
Koch, Marco;
Jin, Sungho;
Argente-Arizon, Pilar;
Argente, Jesús;
Liu, Zhong-Wu;
Zimmer, Marcelo R;
Jeong, Jin Kwon;
Szigeti-Buck, Klara;
Gao, Yuanqing;
Garcia-Caceres, Cristina;
Yi, Chun-Xia;
Salmaso, Natalina;
Vaccarino, Flora M;
Chowen, Julie;
Diano, Sabrina;
Dietrich, Marcelo O;
Tschöp, Matthias H;
Horvath, Tamas L

Publication type:

Article

Hormonal regulation of the hypothalamic melanocortin system.

Published in:

Frontiers in Physiology, 2014, v. 5, p. 1, doi. 10.3389/fphys.2014.00480

By:

Kim, Jung D.;
Leyva, Stephanie;
Diano, Sabrina

Publication type:

Article

Suppression of hypothalamic deiodinase type II activity blunts TRH mRNA decline during fasting

Published in:

FEBS Letters, 2005, v. 579, n. 21, p. 4654, doi. 10.1016/j.febslet.2005.07.035

By:

Coppola, Anna;
Hughes, Jeniter;
Esposito, Emanuela;
Schiavo, Luigi;
Meli, Rosaria;
Diano, Sabrina

Publication type:

Article

Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α.

Published in:

Diabetologia, 2024, v. 67, n. 4, p. 724, doi. 10.1007/s00125-023-06073-5

By:

Liu, Beibei;
Xie, Di;
Huang, Xinmei;
Jin, Sungho;
Dai, Yangyang;
Sun, Xiaoli;
Li, Da;
Bennett, Anton M.;
Diano, Sabrina;
Huang, Yingqun

Publication type:

Article

Hypothalamic glucose-sensing mechanisms.

Published in:

Diabetologia, 2021, v. 64, n. 5, p. 985, doi. 10.1007/s00125-021-05395-6

By:

Yoon, Nal Ae;
Diano, Sabrina

Publication type:

Article

Primate Phencyclidine Model of Schizophrenia: Sex-Specific Effects on Cognition, Brain Derived Neurotrophic Factor, Spine Synapses, and Dopamine Turnover in Prefrontal Cortex.

Published in:

International Journal of Neuropsychopharmacology, 2015, v. 18, n. 6, p. 1, doi. 10.1093/ijnp/pyu048

By:

Elsworth, John D.;
Groman, Stephanie M.;
Jentsch, James D.;
Leranth, Csaba;
Redmond Jr, D. Eugene;
Kim, Jung D.;
Diano, Sabrina;
Roth, Robert H.

Publication type:

Article

Prolyl Endopeptidase-Deficient Mice Have Reduced Synaptic Spine Density in the CA1 Region of the Hippocampus, Impaired LTP, and Spatial Learning and Memory.

Published in:

Cerebral Cortex, 2013, v. 23, n. 8, p. 2007, doi. 10.1093/cercor/bhs199

By:

D'Agostino, Giuseppe;
Kim, Jung Dae;
Liu, Zhong-Wu;
Jeong, Jin Kwon;
Suyama, Shigetomo;
Calignano, Antonio;
Gao, Xiao-Bing;
Schwartz, Michael;
Diano, Sabrina

Publication type:

Article

Nutrient-Dependent Mitochondrial Fission Enhances Osteoblast Function.

Published in:

Nutrients, 2023, v. 15, n. 9, p. 2222, doi. 10.3390/nu15092222

By:

Menale, Ciro;
Trinchese, Giovanna;
Aiello, Immacolata;
Scalia, Giulia;
Dentice, Monica;
Mollica, Maria Pina;
Yoon, Nal Ae;
Diano, Sabrina

Publication type:

Article

Novel analogs of ghrelin: physiological and clinical implications.

Published in:

European Journal of Endocrinology, 2004, p. S71, doi. 10.1530/eje.0.151s071

By:

Halem, Heather A.;
Taylor, John E.;
Dong, Jesse Z.;
Shen, Yeelana;
Datta, Rakesh;
Abizaid, Alfonso;
Diano, Sabrina;
Horvath, Tamas;
Zizzari, Philippe;
Bluet-Pajot, Marie-Thèrèse;
Epelbaum, Jacques;
Culler, Michael D.

Publication type:

Article

alpha-Melanocyte stimulating hormone: production and degradation.

Published in:

Journal of Molecular Medicine, 2010, v. 88, n. 12, p. 1195, doi. 10.1007/s00109-010-0651-0

By:

D'Agostino, Giuseppe;
Diano, Sabrina

Publication type:

Article

Mitochondrial uncoupling proteins in the CNS: in support of function and survival.

Published in:

2005

By:

Andrews, Zane B.;
Diano, Sabrina;
Horvath, Tamas L.

Publication type:

journal article

Opinion: The floating blueprint of hypothalamic feeding circuits.

Published in:

2004

By:

Horvath, Tamas L.;
Diano, Sabrina

Publication type:

Editorial

Corrigendum: Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.

Published in:

2011

By:

Diano, Sabrina;
Liu, Zhong-Wu;
Jeong, Jin Kwon;
Dietrich, Marcelo O;
Ruan, Hai-Bin;
Kim, Esther;
Suyama, Shigetomo;
Kelly, Kaitlin;
Gyengesi, Erika;
Arbiser, Jack L;
Belsham, Denise D;
Sarruf, David A;
Schwartz, Michael W;
Bennett, Anton M;
Shanabrough, Marya;
Mobbs, Charles V;
Yang, Xiaoyong;
Gao, Xiao-Bing;
Horvath, Tamas L

Publication type:

Correction Notice

Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.

Published in:

Nature Medicine, 2011, v. 17, n. 9, p. 1121, doi. 10.1038/nm.2421

By:

Diano, Sabrina;
Liu, Zhong-Wu;
Jeong, Jin Kwon;
Dietrich, Marcelo O;
Ruan, Hai-Bin;
Kim, Esther;
Suyama, Shigetomo;
Kelly, Kaitlin;
Gyengesi, Erika;
Arbiser, Jack L;
Belsham, Denise D;
Sarruf, David A;
Schwartz, Michael W;
Bennett, Anton M;
Shanabrough, Marya;
Mobbs, Charles V;
Yang, Xiaoyong;
Gao, Xiao-Bing;
Horvath, Tamas L

Publication type:

Article

Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals.

Published in:

Nature Medicine, 2007, v. 13, n. 1, p. 89, doi. 10.1038/nm1525

By:

Gao, Qian;
Mezei, Gabor;
Nie, Yongzhan;
Rao, Yan;
Choi, Cheol Soo;
Bechmann, Ingo;
Leranth, Csaba;
Toran-Allerand, Dominique;
Priest, Catherine A.;
Roberts, James L.;
Gao, Xiao-Bing;
Mobbs, Charles;
Shulman, Gerald I.;
Diano, Sabrina;
Horvath, Tamas L.

Publication type:

Article

Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity.

Published in:

2017

By:

Jung Dae Kim;
Chitoku Toda;
Ramírez, Cristina M.;
Fernández-Hernando, Carlos;
Diano, Sabrina;
Kim, Jung Dae;
Toda, Chitoku

Publication type:

journal article

A Role for Uncoupling Proteins in Neuroprotection Following Recurrent Hypoglycemia?

Published in:

Diabetes, 2007, v. 56, p. A166

By:

Mccrimmon, Rory;
Andrews, Zane;
Coppola, Anna;
Cheng, Haiying;
Sherwin, Robert;
Diano, Sabrina

Publication type:

Article

Prolyl Endopeptidase (PREP) is Associated With Male Reproductive Functions and Gamete Physiology in Mice.

Published in:

Journal of Cellular Physiology, 2016, v. 231, n. 3, p. 551, doi. 10.1002/jcp.25178

By:

Dotolo, Raffaele;
Kim, Jung Dae;
Pariante, Paolo;
Minucci, Sergio;
Diano, Sabrina

Publication type:

Article

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus.

Published in:

Nature, 2001, v. 411, n. 6836, p. 480, doi. 10.1038/35078085

By:

Cowley, Michael A.;
Smart, James L.;
Rubinstein, Marcelo;
Cerdan, Marcelo G.;
Diano, Sabrina;
Horvath, Tamas L.;
Cone, Roger D.;
Low, Malcolm J.

Publication type:

Article

Ghrelin controls hippocampal spine synapse density and memory performance.

Published in:

Nature Neuroscience, 2006, v. 9, n. 3, p. 381, doi. 10.1038/nn1656

By:

Diano, Sabrina;
Farr, Susan A.;
Benoit, Stephen C.;
McNay, Ewan C.;
da Silva, Ivaldo;
Horvath, Balazs;
Gaskin, F. Spencer;
Nonaka, Naoko;
Jaeger, Laura B.;
Banks, William A.;
Morley, John E.;
Pinto, Shirly;
Sherwin, Robert S.;
Lin Xu;
Yamada, Kelvin A.;
Sleeman, Mark W.;
Tschöp, Matthias H.;
Horvath, Tamas L.

Publication type:

Article

Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22431-6

By:

Lee, Ming-Liang;
Matsunaga, Hirokazu;
Sugiura, Yuki;
Hayasaka, Takahiro;
Yamamoto, Izumi;
Ishimoto, Taiga;
Imoto, Daigo;
Suematsu, Makoto;
Iijima, Norifumi;
Kimura, Kazuhiro;
Diano, Sabrina;
Toda, Chitoku

Publication type:

Article

UCP2 mediates ghrelin’s action on NPY/AgRP neurons by lowering free radicals.

Published in:

2009

By:

Andrews, Zane B.;
Liu, Zhong-Wu;
Walllingford, Nicholas;
Erion, Derek M.;
Borok, Erzsebet;
Friedman, Jeffery M.;
Tschöp, Matthias H.;
Shanabrough, Marya;
Cline, Gary;
Shulman, Gerald I.;
Coppola, Anna;
Gao, Xiao-Bing;
Horvath, Tamas L.;
Diano, Sabrina

Publication type:

Correction Notice

Plasticity of calcium-permeable AMPA glutamate receptors in Pro- opiomelanocortin neurons.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.25755.001

By:

Shigetomo Suyama;
Ralevski, Alexandra;
Zhong-Wu Liu;
Dietrich, Marcelo O.;
Toshihiko Yada;
Simonds, Stephanie E.;
Cowley, Michael A.;
Xiao-Bing Gao;
Diano, Sabrina;
Horvath, Tamas L.

Publication type:

Article

Monosynaptic Pathway Between the Arcuate Nucleus Expressing Glial Type II Iodothyronine 5′-Deiodinase mRNA and the Median Eminence-Projective TRH Cells of the Rat Paraventricular Nucleus.

Published in:

Journal of Neuroendocrinology, 1998, v. 10, n. 10, p. 731, doi. 10.1046/j.1365-2826.1998.00204.x

By:

Diano, Sabrina;
Naftolin, Frederick;
Goglia, Fernando;
Csernus, Valer;
Horvath, Tamas L.

Publication type:

Article

Leptin Receptor Immunoreactivity is Associated with the Golgi Apparatus of Hypothalamic Neurones and Glial Cells.

Published in:

Journal of Neuroendocrinology, 1998, v. 10, n. 9, p. 647, doi. 10.1046/j.1365-2826.1998.00261.x

By:

Diano, Sabrina;
Kalra, Satya P.;
Horvath, Tamas L.

Publication type:

Article

Kainate Glutamate Receptors (GluR5-7) in the Rat Arcuate Nucleus: Relationship to Tanycytes, Astrocytes, Neurons and Gonadal Steroid Receptors.

Published in:

Journal of Neuroendocrinology, 1998, v. 10, n. 4, p. 239, doi. 10.1046/j.1365-2826.1998.00195.x

By:

Diano, Sabrina;
Naftolin, Frederick;
Horvath, Tamas L.

Publication type:

Article

Role of the Melanocortin System in the Central Regulation of Cardiovascular Functions.

Published in:

Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.725709

By:

Copperi, Francesca;
Kim, Jung Dae;
Diano, Sabrina

Publication type:

Article

Hypothalamic POMC neurons promote cannabinoid-induced feeding.

Published in:

Nature, 2015, v. 519, n. 7541, p. 45, doi. 10.1038/nature14260

By:

Koch, Marco;
Varela, Luis;
Kim, Jae Geun;
Kim, Jung Dae;
Hernández-Nuño, Francisco;
Simonds, Stephanie E.;
Castorena, Carlos M.;
Vianna, Claudia R.;
Elmquist, Joel K.;
Morozov, Yury M.;
Rakic, Pasko;
Bechmann, Ingo;
Cowley, Michael A.;
Szigeti-Buck, Klara;
Dietrich, Marcelo O.;
Gao, Xiao-Bing;
Diano, Sabrina;
Horvath, Tamas L.

Publication type:

Article

Hepatic TET3 contributes to type-2 diabetes by inducing the HNF4α fetal isoform.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-14185-z

By:

Da Li;
Cao, Tiefeng;
Sun, Xiaoli;
Jin, Sungho;
Di Xie;
Huang, Xinmei;
Yang, Xiaoyong;
Carmichael, Gordon G.;
Taylor, Hugh S.;
Diano, Sabrina;
Huang, Yingqun

Publication type:

Article

Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse.

Published in:

2008

By:

Deierborg, Tomas;
Wieloch, Tadeusz;
Diano, Sabrina;
Warden, Craig H;
Horvath, Tamas L;
Mattiasson, Gustav

Publication type:

Correction Notice

Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2008, v. 28, n. 6, p. 1186, doi. 10.1038/jcbfm.2008.8

By:

Olsson, Tomas Deierborg;
Wieloch, Tadeusz;
Diano, Sabrina;
Warden, Craig H.;
Horvath, Tamas L.;
Mattiasson, Gustav

Publication type:

Article

Ecto-nucleoside triphosphate diphosphohydrolase 3 in the ventral and lateral hypothalamic area of female rats: morphological characterization and functional implications.

Published in:

Reproductive Biology & Endocrinology, 2009, v. 7, p. 1, doi. 10.1186/1477-7827-7-31

By:

Kiss, David S.;
Zsarnovszky, Attila;
Horvath, Krisztina;
Gyorffy, Andrea;
Bartha, Tibor;
Hazai, Diana;
Sotonyi, Peter;
Somogyi, Virag;
Frenyo, Laszlo V.;
Diano, Sabrina

Publication type:

Article