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Site‐Specific Hyperphosphorylation Inhibits, Rather than Promotes, Tau Fibrillization, Seeding Capacity, and Its Microtubule Binding.
- Published in:
- Angewandte Chemie, 2020, v. 132, n. 10, p. 4088, doi. 10.1002/ange.201913001
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- Publication type:
- Article
Photo-activatable Cre recombinase regulates gene expression in vivo.
- Published in:
- Scientific Reports, 2015, p. 13627, doi. 10.1038/srep13627
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- Publication type:
- Article
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36058-2
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- Publication type:
- Article
The green tea polyphenol (−)-epigallocatechin gallate prevents the aggregation of tau protein into toxic oligomers at substoichiometric ratios.
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- FEBS Letters, 2015, v. 589, n. 1, p. 77, doi. 10.1016/j.febslet.2014.11.026
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- Publication type:
- Article
In Vivo Microdialysis Reveals Age-Dependent Decrease of Brain Interstitial Fluid Tau Levels in P301S Human Tau Transgenic Mice.
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- Journal of Neuroscience, 2011, v. 31, n. 37, p. 13110, doi. 10.1523/JNEUROSCI.2569-11.2011
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- Publication type:
- Article
Prion-like nuclear aggregation of TDP-43 during heat shock is regulated by HSP40/70 chaperones.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 1, p. 157, doi. 10.1093/hmg/ddt408
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- Publication type:
- Article
An aggregation sensing reporter identifies leflunomide and teriflunomide as polyglutamine aggregate inhibitors.
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- Human Molecular Genetics, 2012, v. 21, n. 3, p. 664, doi. 10.1093/hmg/ddr500
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- Publication type:
- Article
Polyglutamine diseases: emerging concepts in pathogenesis and therapy.
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- Human Molecular Genetics, 2007, v. 16, n. R2, p. R115, doi. 10.1093/hmg/ddm213
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- Publication type:
- Article
Biologically active molecules that reduce polyglutamine aggregation and toxicity.
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- Human Molecular Genetics, 2006, v. 15, n. 13, p. 2114, doi. 10.1093/hmg/ddl135
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- Publication type:
- Article
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy.
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- Science Translational Medicine, 2017, v. 9, n. 374, p. 1, doi. 10.1126/scitranslmed.aag0481
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- Publication type:
- Article
Amyotrophic lateral sclerosis and organ donation: Is there risk of disease transmission?
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- Annals of Neurology, 2012, v. 72, n. 6, p. 832, doi. 10.1002/ana.23684
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- Publication type:
- Article
Tau seeding in chronic traumatic encephalopathy parallels disease severity.
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- Acta Neuropathologica, 2021, v. 142, n. 6, p. 951, doi. 10.1007/s00401-021-02373-5
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- Publication type:
- Article
Tau strains shape disease.
- Published in:
- Acta Neuropathologica, 2021, v. 142, n. 1, p. 57, doi. 10.1007/s00401-021-02301-7
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- Publication type:
- Article
Rebuttal to Drs. Grinberg and Heinsen.
- Published in:
- 2018
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- Publication type:
- Letter to the Editor
Tau seeding activity begins in the transentorhinal/entorhinal regions and anticipates phospho-tau pathology in Alzheimer’s disease and PART.
- Published in:
- Acta Neuropathologica, 2018, v. 136, n. 1, p. 57, doi. 10.1007/s00401-018-1855-6
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- Publication type:
- Article
Prion-like mechanisms in neurodegenerative diseases.
- Published in:
- Nature Reviews Neuroscience, 2010, v. 11, n. 3, p. 155, doi. 10.1038/nrn2786
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- Publication type:
- Article
Anti-tau antibody reduces insoluble tau and decreases brain atrophy.
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- Annals of Clinical & Translational Neurology, 2015, v. 2, n. 3, p. 278, doi. 10.1002/acn3.176
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- Publication type:
- Article
Deep learning reveals disease-specific signatures of white matter pathology in tauopathies.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01271-x
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- Publication type:
- Article
Anatomic survey of seeding in Alzheimer's disease brains reveals unexpected patterns.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01255-x
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- Publication type:
- Article
Ultrasensitive tau biosensor cells detect no seeding in Alzheimer's disease CSF.
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- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01185-8
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- Publication type:
- Article
Alzheimer's disease risk modifier genes do not affect tau aggregate uptake, seeding or maintenance in cell models.
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- FEBS Open Bio, 2020, v. 10, n. 9, p. 1912, doi. 10.1002/2211-5463.12928
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- Publication type:
- Article
Fate and propagation of endogenously formed Tau aggregates in neuronal cells.
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- EMBO Molecular Medicine, 2020, v. 12, n. 12, p. 1, doi. 10.15252/emmm.202012025
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- Publication type:
- Article
The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition.
- Published in:
- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0215-7
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- Publication type:
- Article
Site‐Specific Hyperphosphorylation Inhibits, Rather than Promotes, Tau Fibrillization, Seeding Capacity, and Its Microtubule Binding.
- Published in:
- Angewandte Chemie International Edition, 2020, v. 59, n. 10, p. 4059, doi. 10.1002/anie.201913001
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- Publication type:
- Article
Propagation of tau misfolding: A new mechanism for Alzheimer's disease?
- Published in:
- 2010
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- Publication type:
- Abstract
Tau seeding in cases of multiple sclerosis.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01444-2
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- Publication type:
- Article
Travels with tau prions.
- Published in:
- Cytoskeleton, 2024, v. 81, n. 1, p. 83, doi. 10.1002/cm.21806
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- Publication type:
- Article
Intravitreal Administration of HA-1077, a ROCK Inhibitor, Improves Retinal Function in a Mouse Model of Huntington Disease.
- Published in:
- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056026
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- Publication type:
- Article
Protein Phosphatase 1 Dephosphorylates Profilin-1 at Ser-137.
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- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032802
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- Publication type:
- Article
F-Actin Binding Regions on the Androgen Receptor and Huntingtin Increase Aggregation and Alter Aggregate Characteristics.
- Published in:
- PLoS ONE, 2010, v. 5, n. 2, p. 1, doi. 10.1371/journal.pone.0009053
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- Publication type:
- Article
Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue.
- Published in:
- Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0442-8
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- Publication type:
- Article
VCP suppresses proteopathic seeding in neurons.
- Published in:
- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-022-00532-0
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- Publication type:
- Article
Tau local structure shields an amyloid-forming motif and controls aggregation propensity.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10355-1
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- Publication type:
- Article
Correction to: Anatomic survey of seeding in Alzheimer's disease brains reveals unexpected patterns.
- Published in:
- 2024
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- Publication type:
- Correction Notice
DnaJC7 specifically regulates tau seeding.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.86936
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- Publication type:
- Article
Mechanisms of Protein Seeding in Neurodegenerative Diseases.
- Published in:
- JAMA Neurology, 2013, v. 70, n. 3, p. 304, doi. 10.1001/jamaneurol.2013.1453
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- Publication type:
- Article
Glucocorticoid modulation ofandrogen receptor nuclear aggregation and cellular toxicity is associated withdistinct forms of soluble expanded polyglutamine protein.
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- Human Molecular Genetics, 2001, v. 10, n. 26, p. 3063, doi. 10.1093/hmg/10.26.3063
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- Publication type:
- Article
ROCK and PRK-2 mediate the inhibitory effect of Y-27632 on polyglutamine aggregation
- Published in:
- FEBS Letters, 2008, v. 582, n. 12, p. 1637, doi. 10.1016/j.febslet.2008.04.009
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- Publication type:
- Article