Works by Di Iorio, Patrizia

Results: 34

Significant Changes in Low-Abundance Protein Content Detected by Proteomic Analysis of Urine from Patients with Renal Stones After Extracorporeal Shock Wave Lithotripsy.

Published in:

Biology (2079-7737), 2025, v. 14, n. 5, p. 482, doi. 10.3390/biology14050482

By:

Carestia, Elena;
Di Giuseppe, Fabrizio;
Kazemi, Mohammad;
Ramahi, Massoumeh;
Priyadarshi, Uditanshu;
Giuliani, Patricia;
De Francesco, Piergustavo;
Schips, Luigi;
Di Ilio, Carmine;
Ciccarelli, Renata;
Di Iorio, Patrizia;
Angelucci, Stefania

Publication type:

Article

The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor.

Published in:

Genes, 2018, v. 9, n. 2, p. 105, doi. 10.3390/genes9020105

By:

Zuccarini, Mariachiara;
Giuliani, Patricia;
Ziberi, Sihana;
Carluccio, Marzia;
Di Iorio, Patrizia;
Caciagli, Francesco;
Ciccarelli, Renata

Publication type:

Article

Guanosine protects against reperfusion injury in rat brains after ischemic stroke.

Published in:

Journal of Neuroscience Research, 2013, v. 91, n. 2, p. 262, doi. 10.1002/jnr.23156

By:

Connell, Barry J.;
Di Iorio, Patrizia;
Sayeed, Iqbal;
Ballerini, Patrizia;
Saleh, Monique C.;
Giuliani, Patricia;
Saleh, Tarek M.;
Rathbone, Michel P.;
Su, Caixin;
Jiang, Shucui

Publication type:

Article

Guanosine modulates K+ membrane currents in SH-SY5Y cells: involvement of adenosine receptors.

Published in:

Pflügers Archiv: European Journal of Physiology, 2022, v. 474, n. 11, p. 1133, doi. 10.1007/s00424-022-02741-4

By:

Gambino, Giuditta;
Giglia, Giuseppe;
Gallo, Daniele;
Scordino, Miriana;
Giardina, Costanza;
Zuccarini, Mariachiara;
Di Iorio, Patrizia;
Giuliani, Patricia;
Ciruela, Francisco;
Ferraro, Giuseppe;
Mudò, Giuseppa;
Sardo, Pierangelo;
Di Liberto, Valentina

Publication type:

Article

Upregulation of Epithelial-To-Mesenchymal Transition Markers and P2X7 Receptors Is Associated to Increased Invasiveness Caused by P2X7 Receptor Stimulation in Human Glioblastoma Stem Cells.

Published in:

Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010085

By:

Ziberi, Sihana;
Zuccarini, Mariachiara;
Carluccio, Marzia;
Giuliani, Patricia;
Ricci-Vitiani, Lucia;
Pallini, Roberto;
Caciagli, Francesco;
Di Iorio, Patrizia;
Ciccarelli, Renata

Publication type:

Article

The Guanine-Based Purinergic System: The Tale of An Orphan Neuromodulation.

Published in:

Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00158

By:

Di Liberto, Valentina;
Mudò, Giuseppa;
Garozzo, Roberta;
Frinchi, Monica;
Fernandez-Dueñas, Víctor;
Di Iorio, Patrizia;
Ciccarelli, Renata;
Caciagli, Francesco;
Condorelli, Daniele F.;
Ciruela, Francisco;
Belluardo, Natale

Publication type:

Article

Purine nucleosides protect injured neurons and stimulate neuronal regeneration by intracellular and membrane receptor-mediated mechanisms.

Published in:

Drug Development Research, 2001, v. 52, n. 1/2, p. 303, doi. 10.1002/ddr.1128

By:

Di Iorio, Patrizia;
Caciagli, Francesco;
Giuliani, Patricia;
Ballerini, Patrizia;
Ciccarelli, Renata;
Sperling, Oded;
Zoref-Shani, Esther;
Benowitz, Larry;
Traversa, Ugo;
Bombi, Giulia;
Florio, Tulio;
Virgilio, Antonella;
Andrew, Craig M.;
Crocker, Candice E.;
Werstiuk, Eva S.;
Middlemiss, Pamela J.;
Rathbone, Michel P.

Publication type:

Article

Specific [[sup3]H]-guanosine binding sites in rat brain membranes.

Published in:

British Journal of Pharmacology, 2002, v. 135, n. 4, p. 969, doi. 10.1038/sj.bjp.0704542

By:

Traversa, Ugo;
Bombi, Giulia;
Di Iorio, Patrizia;
Ciccarelli, Renata;
Werstiuk, Eva S.;
Rathbone, Michel P.

Publication type:

Article

Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia.

Published in:

Glia (0894-1491), 1999, v. 25, n. 1, p. 93, doi. 10.1002/(SICI)1098-1136(19990101)25:1<93::AID-GLIA9>3.0.CO;2-N

By:

Ciccarelli, Renata;
Di Iorio, Patrizia;
Giuliani, Patricia;
D'Alimonte, Iolanda;
Ballerini, Patrizia;
Caciagli, Francesco;
Rathbone, Michel P.

Publication type:

Article

Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture.

Published in:

Glia (0894-1491), 1997, v. 21, n. 4, p. 390, doi. 10.1002/(SICI)1098-1136(199712)21:4<390::AID-GLIA6>3.0.CO;2-7

By:

Ciccarelli, Renata;
Sureda, Francesc X.;
Casabona, Giacomo;
Di Iorio, Patrizia;
Caruso, Alessandra;
Spinella, Francesca;
Filippo Condorelli, Daniele;
Nicoletti, Ferdinando;
Caciagli, Francesco

Publication type:

Article

In Search of a Role for Extracellular Purine Enzymes in Bone Function.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 5, p. 679, doi. 10.3390/biom11050679

By:

Zuccarini, Mariachiara;
Giuliani, Patricia;
Caciagli, Francesco;
Ciccarelli, Renata;
Di Iorio, Patrizia;
Takegahara, Noriko

Publication type:

Article

Guanine inhibits the growth of human glioma and melanoma cell lines by interacting with GPR23.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.970891

By:

Garozzo, Roberta;
Zuccarini, Mariachiara;
Giuliani, Patricia;
Di Liberto, Valentina;
Mudò, Giuseppa;
Caciagli, Francesco;
Ciccarelli, Renata;
Ciruela, Francisco;
Di Iorio, Patrizia;
Condorelli, Daniele F.

Publication type:

Article

Metabolic Changes Induced by Purinergic Signaling: Role in Food Intake.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.655989

By:

Caruso, Vanni;
Zuccarini, Mariachiara;
Di Iorio, Patrizia;
Muhammad, Ishaq;
Ronci, Maurizio

Publication type:

Article

Investigating the Role of Guanosine on Human Neuroblastoma Cell Differentiation and the Underlying Molecular Mechanisms.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.658806

By:

Belluardo, Natale;
Mudò, Giuseppa;
Di Liberto, Valentina;
Frinchi, Monica;
Condorelli, Daniele F.;
Traversa, Ugo;
Ciruela, Francisco;
Ciccarelli, Renata;
Di Iorio, Patrizia;
Giuliani, Patricia

Publication type:

Article

Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.654426

By:

Beggiato, Sarah;
Zuccarini, Mariachiara;
Cassano, Tommaso;
Borroto-Escuela, Dasiel Oscar;
Di Iorio, Patrizia;
Schwarcz, Robert;
Fuxe, Kjell;
Ferraro, Luca

Publication type:

Article

Guanosine Mechanisms of Action: Toward Molecular Targets.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.653146

By:

Massari, Caio M.;
Zuccarini, Mariachiara;
Di Iorio, Patrizia;
Tasca, Carla I.

Publication type:

Article

Altered distribution and function of A2A adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease.

Published in:

European Journal of Neuroscience, 2009, v. 30, n. 6, p. 1023, doi. 10.1111/j.1460-9568.2009.06897.x

By:

D'Alimonte, Iolanda;
D'Auro, Mariagrazia;
Citraro, Rita;
Biagioni, Francesca;
Jiang, Shucui;
Nargi, Eleonora;
Buccella, Silvana;
Di Iorio, Patrizia;
Giuliani, Patricia;
Ballerini, Patrizia;
Caciagli, Francesco;
Russo, Emilio;
De Sarro, Giovambattista;
Ciccarelli, Renata

Publication type:

Article

Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT1 receptors and mitogen-activated protein kinase pathway.

Published in:

European Journal of Neuroscience, 2004, v. 20, n. 6, p. 1514, doi. 10.1111/j.1460-9568.2004.03613.x

By:

Ciccarelli, Renata;
D'Alimonte, Iolanda;
Santavenere, Clara;
D'Auro, Mariagrazia;
Ballerini, Patrizia;
Nargi, Eleonora;
Buccella, Silvana;
Nicosia Folco, Simonetta, Giancarlo;
Caciagli, Francesco;
Di Iorio, Patrizia

Publication type:

Article

Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells.

Published in:

Journal of Neurochemistry, 2017, v. 141, n. 2, p. 208, doi. 10.1111/jnc.14004

By:

Giuliani, Patricia;
Zuccarini, Mariachiara;
Buccella, Silvana;
Peña‐Altamira, Luis Emiliano;
Polazzi, Elisabetta;
Virgili, Marco;
Monti, Barbara;
Poli, Alessandro;
Rathbone, Michel P.;
Iorio, Patrizia Di;
Ciccarelli, Renata;
Caciagli, Francesco

Publication type:

Article

Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 3, p. 1172, doi. 10.3390/jcm12031172

By:

Zuccarini, Mariachiara;
Pruccoli, Letizia;
Balducci, Martina;
Giuliani, Patricia;
Caciagli, Francesco;
Ciccarelli, Renata;
Di Iorio, Patrizia

Publication type:

Article

Changes Induced by P2X7 Receptor Stimulation of Human Glioblastoma Stem Cells in the Proteome of Extracellular Vesicles Isolated from Their Secretome.

Published in:

Cells (2073-4409), 2024, v. 13, n. 7, p. 571, doi. 10.3390/cells13070571

By:

Di Giuseppe, Fabrizio;
Ricci-Vitiani, Lucia;
Pallini, Roberto;
Di Pietro, Roberta;
Di Iorio, Patrizia;
Ascani, Giuliano;
Ciccarelli, Renata;
Angelucci, Stefania

Publication type:

Article

Multipotent Stromal Cells from Subcutaneous Adipose Tissue of Normal Weight and Obese Subjects: Modulation of Their Adipogenic Differentiation by Adenosine A 1 Receptor Ligands.

Published in:

Cells (2073-4409), 2021, v. 10, n. 12, p. 3560, doi. 10.3390/cells10123560

By:

Zuccarini, Mariachiara;
Lambertucci, Catia;
Carluccio, Marzia;
Giuliani, Patricia;
Ronci, Maurizio;
Spinaci, Andrea;
Volpini, Rosaria;
Ciccarelli, Renata;
Di Iorio, Patrizia

Publication type:

Article

Adenine-Based Purines and Related Metabolizing Enzymes: Evidence for Their Impact on Tumor Extracellular Vesicle Activities.

Published in:

Cells (2073-4409), 2021, v. 10, n. 1, p. 188, doi. 10.3390/cells10010188

By:

Di Iorio, Patrizia;
Ciccarelli, Renata

Publication type:

Article

Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00110

By:

Zuccarini, Mariachiara;
Giuliani, Patricia;
Frinchi, Monica;
Mudò, Giuseppa;
Serio, Rosa Maria;
Belluardo, Natale;
Buccella, Silvana;
Carluccio, Marzia;
Condorelli, Daniele F.;
Caciagli, Francesco;
Ciccarelli, Renata;
Di Iorio, Patrizia

Publication type:

Article

Proteomics Studies on Extracellular Vesicles Derived from Glioblastoma: Where Do We Stand?

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 18, p. 9778, doi. 10.3390/ijms25189778

By:

Giuliani, Patricia;
De Simone, Chiara;
Febo, Giorgia;
Bellasame, Alessia;
Tupone, Nicola;
Di Virglio, Vimal;
di Giuseppe, Fabrizio;
Ciccarelli, Renata;
Di Iorio, Patrizia;
Angelucci, Stefania

Publication type:

Article

Bidirectional Control between Cholesterol Shuttle and Purine Signal at the Central Nervous System.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 15, p. 8683, doi. 10.3390/ijms23158683

By:

Passarella, Daniela;
Ronci, Maurizio;
Di Liberto, Valentina;
Zuccarini, Mariachiara;
Mudò, Giuseppa;
Porcile, Carola;
Frinchi, Monica;
Di Iorio, Patrizia;
Ulrich, Henning;
Russo, Claudio

Publication type:

Article

Purinergic Signaling in Oral Tissues.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 7790, doi. 10.3390/ijms23147790

By:

Zuccarini, Mariachiara;
Giuliani, Patricia;
Ronci, Maurizio;
Caciagli, Francesco;
Caruso, Vanni;
Ciccarelli, Renata;
Di Iorio, Patrizia

Publication type:

Article

Adipose Stromal/Stem Cell-Derived Extracellular Vesicles: Potential Next-Generation Anti-Obesity Agents.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1543, doi. 10.3390/ijms23031543

By:

Zuccarini, Mariachiara;
Giuliani, Patricia;
Di Liberto, Valentina;
Frinchi, Monica;
Caciagli, Francesco;
Caruso, Vanni;
Ciccarelli, Renata;
Mudò, Giuseppa;
Di Iorio, Patrizia

Publication type:

Article

Pros and Cons of Pharmacological Manipulation of cGMP-PDEs in the Prevention and Treatment of Breast Cancer.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 262, doi. 10.3390/ijms23010262

By:

Di Iorio, Patrizia;
Ronci, Maurizio;
Giuliani, Patricia;
Caciagli, Francesco;
Ciccarelli, Renata;
Caruso, Vanni;
Beggiato, Sarah;
Zuccarini, Mariachiara

Publication type:

Article

Guanosine-Mediated Anxiolytic-Like Effect: Interplay with Adenosine A 1 and A 2A Receptors.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 23, p. 9281, doi. 10.3390/ijms21239281

By:

Frinchi, Monica;
Verdi, Vincenzo;
Plescia, Fulvio;
Ciruela, Francisco;
Grillo, Maria;
Garozzo, Roberta;
Condorelli, Daniele F.;
Di Iorio, Patrizia;
Caciagli, Francesco;
Ciccarelli, Renata;
Belluardo, Natale;
Di Liberto, Valentina;
Mudò, Giuseppa

Publication type:

Article

The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes.

Published in:

Glia (0894-1491), 2004, v. 46, n. 4, p. 356, doi. 10.1002/glia.20002

By:

Patrizia Di Iorio;
Patrizia Ballerini;
Ugo Traversa;
Ferdinando Nicoletti;
Iolanda D'Alimonte;
Sonya Kleywegt;
Eva S. Werstiuk;
Michel P. Rathbone;
Francesco Caciagli;
Renata Ciccarelli

Publication type:

Article

Mechanisms of apoptosis induced by purine nucleosides in astrocytes.

Published in:

Glia (0894-1491), 2002, v. 38, n. 3, p. 179, doi. 10.1002/glia.10055

By:

Di Iorio, Patrizia;
Kleywegt, Sonya;
Ciccarelli, Renata;
Traversa, Ugo;
Andrew, Craig M.;
Crocker, Candice E.;
Werstiuk, Eva S.;
Rathbone, Michel P.

Publication type:

Article

Cultured astrocyte proliferation induced by extracellular guanosine involves endogenous adenosine and is raised by the co-presence of microglia.

Published in:

Glia (0894-1491), 2000, v. 29, n. 3, p. 202, doi. 10.1002/(SICI)1098-1136(20000201)29:3<202::AID-GLIA2>3.0.CO;2-C

By:

Ciccarelli, Renata;
Di Iorio, Patrizia;
D'Alimonte, Iolanda;
Giuliani, Patricia;
Florio, Tullio;
Caciagli, Francesco;
Middlemiss, Pamela J.;
Rathbone, Michel P.

Publication type:

Article

Region-specific effects on brain metabolites of hypoxia and hyperoxia overlaid on cerebral ischemia in young and old rats: a quantitative proton magnetic resonance spectroscopy study.

Published in:

Journal of Biomedical Science, 2010, v. 17, p. 1, doi. 10.1186/1423-0127-17-14

By:

Macri, Maria A.;
D'Alessandro, Nicola;
Di Giulio, Camillo;
Di Iorio, Patrizia;
Di Luzio, Silvano;
Giuliani, Patricia;
Esposito, Ennio;
Pokorski, Mieczyslaw

Publication type:

Article

Works by Di Iorio, Patrizia

Significant Changes in Low-Abundance Protein Content Detected by Proteomic Analysis of Urine from Patients with Renal Stones After Extracorporeal Shock Wave Lithotripsy.

The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor.

Guanosine protects against reperfusion injury in rat brains after ischemic stroke.

Guanosine modulates K<sup>+</sup> membrane currents in SH-SY5Y cells: involvement of adenosine receptors.

Upregulation of Epithelial-To-Mesenchymal Transition Markers and P2X7 Receptors Is Associated to Increased Invasiveness Caused by P2X7 Receptor Stimulation in Human Glioblastoma Stem Cells.

The Guanine-Based Purinergic System: The Tale of An Orphan Neuromodulation.

Purine nucleosides protect injured neurons and stimulate neuronal regeneration by intracellular and membrane receptor-mediated mechanisms.

Specific [[sup3]H]-guanosine binding sites in rat brain membranes.

Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia.

Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture.

In Search of a Role for Extracellular Purine Enzymes in Bone Function.

Guanine inhibits the growth of human glioma and melanoma cell lines by interacting with GPR23.

Metabolic Changes Induced by Purinergic Signaling: Role in Food Intake.

Investigating the Role of Guanosine on Human Neuroblastoma Cell Differentiation and the Underlying Molecular Mechanisms.

Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?

Guanosine Mechanisms of Action: Toward Molecular Targets.

Altered distribution and function of A<sub>2A</sub> adenosine receptors in the brain of WAG/Rij rats with genetic absence epilepsy, before and after appearance of the disease.

Cysteinyl-leukotrienes are released from astrocytes and increase astrocyte proliferation and glial fibrillary acidic protein via cys-LT<sub>1</sub> receptors and mitogen-activated protein kinase pathway.

Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells.

Influence of Guanine-Based Purines on the Oxidoreductive Reactions Involved in Normal or Altered Brain Functions.

Changes Induced by P2X7 Receptor Stimulation of Human Glioblastoma Stem Cells in the Proteome of Extracellular Vesicles Isolated from Their Secretome.

Multipotent Stromal Cells from Subcutaneous Adipose Tissue of Normal Weight and Obese Subjects: Modulation of Their Adipogenic Differentiation by Adenosine A 1 Receptor Ligands.

Adenine-Based Purines and Related Metabolizing Enzymes: Evidence for Their Impact on Tumor Extracellular Vesicle Activities.

Uncovering the Signaling Pathway behind Extracellular Guanine-Induced Activation of NO System: New Perspectives in Memory-Related Disorders.

Proteomics Studies on Extracellular Vesicles Derived from Glioblastoma: Where Do We Stand?

Bidirectional Control between Cholesterol Shuttle and Purine Signal at the Central Nervous System.

Purinergic Signaling in Oral Tissues.

Adipose Stromal/Stem Cell-Derived Extracellular Vesicles: Potential Next-Generation Anti-Obesity Agents.

Pros and Cons of Pharmacological Manipulation of cGMP-PDEs in the Prevention and Treatment of Breast Cancer.

Guanosine-Mediated Anxiolytic-Like Effect: Interplay with Adenosine A 1 and A 2A Receptors.

The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes.

Mechanisms of apoptosis induced by purine nucleosides in astrocytes.

Cultured astrocyte proliferation induced by extracellular guanosine involves endogenous adenosine and is raised by the co-presence of microglia.

Region-specific effects on brain metabolites of hypoxia and hyperoxia overlaid on cerebral ischemia in young and old rats: a quantitative proton magnetic resonance spectroscopy study.