Found: 21
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Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target.
- Published in:
- Cell Death & Disease, 2020, v. 11, n. 4, p. 1, doi. 10.1038/s41419-020-2463-7
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- Article
Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
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- Journal of Cell Biology, 2007, v. 177, n. 2, p. 277, doi. 10.1083/jcb.200606065
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- Article
Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies.
- Published in:
- Nature Communications, 2016, v. 7, n. 5, p. 11734, doi. 10.1038/ncomms11734
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- Article
Dissociation of Bak α1 helix from the core and latch domains is required for apoptosis.
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- Nature Communications, 2015, v. 6, n. 4, p. 6841, doi. 10.1038/ncomms7841
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- Article
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer.
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- Science Translational Medicine, 2017, v. 9, n. 401, p. 1, doi. 10.1126/scitranslmed.aam7049
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- Article
Therapeutic targeting of mitophagy in Parkinson’s disease.
- Published in:
- Biochemical Society Transactions, 2022, v. 50, n. 2, p. 783, doi. 10.1042/BST20211107
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- Article
VDAC2 and the BCL-2 family of proteins.
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- Biochemical Society Transactions, 2021, v. 49, n. 6, p. 2787, doi. 10.1042/BST20210753
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- Article
Multigene family isoform profiling from blood cell lineages.
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- BMC Genomics, 2002, v. 3, p. 22, doi. 10.1186/1471-2164-3-22
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- Article
Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.
- Published in:
- Oncogene, 2003, v. 22, n. 17, p. 2643, doi. 10.1038/sj.onc.1206326
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- Article
Disordered clusters of Bak dimers rupture mitochondria during apoptosis.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.19944
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- Article
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell.
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- eLife, 2015, p. 1, doi. 10.7554/eLife.10809
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- Article
Translocation of a Bak C-Terminus Mutant from Cytosol to Mitochondria to Mediate Cytochrome c Release: Implications for Bak and Bax Apoptotic Function.
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- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0031510
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- Article
A new crystal form of GABARAPL2.
- Published in:
- Acta Crystallographica: Section F, Structural Biology Communications, 2021, v. 77, n. 5, p. 140, doi. 10.1107/S2053230X21004489
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- Article
Mesenchymal stromal cell apoptosis is required for their therapeutic function.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26834-3
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- Article
Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis.
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- PLoS Biology, 2024, v. 22, n. 5, p. 1, doi. 10.1371/journal.pbio.3002617
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- Article
Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1.
- Published in:
- Nature Immunology, 2007, v. 8, n. 8, p. 856, doi. 10.1038/ni1487
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- Article
Dynamic reconfiguration of pro‐apoptotic BAK on membranes.
- Published in:
- EMBO Journal, 2021, v. 40, n. 20, p. 1, doi. 10.15252/embj.2020107237
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- Article
Too much death can kill you: inhibiting intrinsic apoptosis to treat disease.
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- EMBO Journal, 2021, v. 40, n. 14, p. 1, doi. 10.15252/embj.2020107341
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- Article
Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy.
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- EMBO Journal, 2019, v. 38, n. 2, p. N.PAG, doi. 10.15252/embj.201899916
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- Article
Doughnuts, daisy chains and crescent moons: the quest for the elusive apoptotic pore.
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- EMBO Journal, 2016, v. 35, n. 4, p. 371, doi. 10.15252/embj.201593723
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- Article
Lymphotoxin α induces apoptosis, necroptosis and inflammatory signals with the same potency as tumour necrosis factor.
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- FEBS Journal, 2013, v. 280, n. 21, p. 5283, doi. 10.1111/febs.12419
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- Article