Works by Dewachter, Ilse

Results: 52
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    Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study.

    Published in:
    JAMA Neurology, 2019, v. 76, n. 8, p. 915, doi. 10.1001/jamaneurol.2019.1424
    By:
    • Hanseeuw, Bernard J.;
    • Betensky, Rebecca A.;
    • Jacobs, Heidi I. L.;
    • Schultz, Aaron P.;
    • Sepulcre, Jorge;
    • Becker, J. Alex;
    • Cosio, Danielle M. Orozco;
    • Farrell, Michelle;
    • Quiroz, Yakeel T.;
    • Mormino, Elizabeth C.;
    • Buckley, Rachel F.;
    • Papp, Kathryn V.;
    • Amariglio, Rebecca A.;
    • Dewachter, Ilse;
    • Ivanoiu, Adrian;
    • Huijbers, Willem;
    • Hedden, Trey;
    • Marshall, Gad A.;
    • Chhatwal, Jasmeer P.;
    • Rentz, Dorene M.
    Publication type:
    Article
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    Loss of γ-Secretase Function Impairs Endocytosis of Lipoprotein Particles and Membrane Cholesterol Homeostasis.

    Published in:
    Journal of Neuroscience, 2008, v. 28, n. 46, p. 12094, doi. 10.1523/JNEUROSCI.2635-08.2008
    By:
    • Tamboli, Irfan Y.;
    • Prager, Kai;
    • Thal, Dietmar R.;
    • Thelen, Karin M.;
    • Dewachter, Ilse;
    • Pietrzik, Claus U.;
    • St. George-Hyslop, Peter;
    • Sisodia, Sangram S.;
    • De Strooper, Bart;
    • Heneka, Michael T.;
    • Filippov, Mikhail A.;
    • Müller, Ulrike;
    • van Leuven, Fred;
    • Lütjohann, Dieter;
    • Walter, Jochen
    Publication type:
    Article
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    Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models.

    Published in:
    Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01748-5
    By:
    • Basheer, Neha;
    • Buee, Luc;
    • Brion, Jean-Pierre;
    • Smolek, Tomas;
    • Muhammadi, Muhammad Khalid;
    • Hritz, Jozef;
    • Hromadka, Tomas;
    • Dewachter, Ilse;
    • Wegmann, Susanne;
    • Landrieu, Isabelle;
    • Novak, Petr;
    • Mudher, Amritpal;
    • Zilka, Norbert
    Publication type:
    Article
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    Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.

    Published in:
    Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-41399-4
    By:
    • Bogie, Jeroen;
    • Hoeks, Cindy;
    • Schepers, Melissa;
    • Tiane, Assia;
    • Cuypers, Ann;
    • Leijten, Frank;
    • Chintapakorn, Yupyn;
    • Suttiyut, Thiti;
    • Pornpakakul, Surachai;
    • Struik, Dicky;
    • Kerksiek, Anja;
    • Liu, Hong-Bing;
    • Hellings, Niels;
    • Martinez-Martinez, Pilar;
    • Jonker, Johan W.;
    • Dewachter, Ilse;
    • Sijbrands, Eric;
    • Walter, Jochen;
    • Hendriks, Jerome;
    • Groen, Albert
    Publication type:
    Article
    15

    Amyloid precursor protein controls cholesterol turnover needed for neuronal activity.

    Published in:
    EMBO Molecular Medicine, 2013, v. 5, n. 4, p. 608, doi. 10.1002/emmm.201202215
    By:
    • Pierrot, Nathalie;
    • Tyteca, Donatienne;
    • D'auria, Ludovic;
    • Dewachter, Ilse;
    • Gailly, Philippe;
    • Hendrickx, Aurélie;
    • Tasiaux, Bernadette;
    • Haylani, Laetitia El;
    • Muls, Nathalie;
    • N'Kuli, Francisca;
    • Laquerrière, Annie;
    • Demoulin, Jean‐Baptiste;
    • Campion, Dominique;
    • Brion, Jean‐Pierre;
    • Courtoy, Pierre J.;
    • Kienlen‐Campard, Pascal;
    • Octave, Jean‐Noël
    Publication type:
    Article
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    Tau association with synaptic vesicles causes presynaptic dysfunction.

    Published in:
    Nature Communications, 2017, v. 8, n. 5, p. 15295, doi. 10.1038/ncomms15295
    By:
    • Zhou, Lujia;
    • McInnes, Joseph;
    • Wierda, Keimpe;
    • Holt, Matthew;
    • Herrmann, Abigail G.;
    • Jackson, Rosemary J.;
    • Wang, Yu-Chun;
    • Swerts, Jef;
    • Beyens, Jelle;
    • Miskiewicz, Katarzyna;
    • Vilain, Sven;
    • Dewachter, Ilse;
    • Moechars, Diederik;
    • De Strooper, Bart;
    • Spires-Jones, Tara L.;
    • De Wit, Joris;
    • Verstreken, Patrik
    Publication type:
    Article
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    Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.

    Published in:
    Acta Neuropathologica, 2017, v. 133, n. 5, p. 731, doi. 10.1007/s00401-016-1663-9
    By:
    • Wang, Peng;
    • Joberty, Gerard;
    • Buist, Arjan;
    • Vanoosthuyse, Alexandre;
    • Stancu, Ilie-Cosmin;
    • Vasconcelos, Bruno;
    • Pierrot, Nathalie;
    • Faelth-Savitski, Maria;
    • Kienlen-Campard, Pascal;
    • Octave, Jean-Noël;
    • Bantscheff, Marcus;
    • Drewes, Gerard;
    • Moechars, Diederik;
    • Dewachter, Ilse
    Publication type:
    Article
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    Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.

    Published in:
    Acta Neuropathologica, 2015, v. 129, n. 6, p. 875, doi. 10.1007/s00401-015-1413-4
    By:
    • Stancu, Ilie-Cosmin;
    • Vasconcelos, Bruno;
    • Ris, Laurence;
    • Wang, Peng;
    • Villers, Agnès;
    • Peeraer, Eve;
    • Buist, Arjan;
    • Terwel, Dick;
    • Baatsen, Peter;
    • Oyelami, Tutu;
    • Pierrot, Nathalie;
    • Casteels, Cindy;
    • Bormans, Guy;
    • Kienlen-Campard, Pascal;
    • Octave, Jean-Nöel;
    • Moechars, Diederik;
    • Dewachter, Ilse
    Publication type:
    Article
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    CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.

    Published in:
    Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01204-8
    By:
    • Lodder, Chritica;
    • Scheyltjens, Isabelle;
    • Stancu, Ilie Cosmin;
    • Botella Lucena, Pablo;
    • Gutiérrez de Ravé, Manuel;
    • Vanherle, Sarah;
    • Vanmierlo, Tim;
    • Cremers, Niels;
    • Vanrusselt, Hannah;
    • Brône, Bert;
    • Hanseeuw, Bernard;
    • Octave, Jean-Noël;
    • Bottelbergs, Astrid;
    • Movahedi, Kiavash;
    • Dewachter, Ilse
    Publication type:
    Article
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    GSK-3?/? kinases and amyloid production in vivo.

    Published in:
    Nature, 2011, v. 480, n. 7376, p. E4, doi. 10.1038/nature10615
    By:
    • Jaworski, Tomasz;
    • Dewachter, Ilse;
    • Lechat, Benoit;
    • Gees, Maarten;
    • Kremer, Anna;
    • Demedts, David;
    • Borghgraef, Peter;
    • Devijver, Herman;
    • Kügler, Seb;
    • Patel, Satish;
    • Woodgett, Jim R.;
    • Van Leuven, Fred
    Publication type:
    Article
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    Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5885, doi. 10.1002/alz.13412
    By:
    • Borchert, Robin J.;
    • Azevedo, Tiago;
    • Badhwar, AmanPreet;
    • Bernal, Jose;
    • Betts, Matthew;
    • Bruffaerts, Rose;
    • Burkhart, Michael C.;
    • Dewachter, Ilse;
    • Gellersen, Helena M.;
    • Low, Audrey;
    • Lourida, Ilianna;
    • Machado, Luiza;
    • Madan, Christopher R.;
    • Malpetti, Maura;
    • Mejia, Jhony;
    • Michopoulou, Sofia;
    • Muñoz‐Neira, Carlos;
    • Pepys, Jack;
    • Peres, Marion;
    • Phillips, Veronica
    Publication type:
    Article
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    MOLECULAR MECHANISMS OF ABETA-INDUCED TAU-PATHOLOGY: ANALYSIS OF CROSS-SEEDING OF ABETA AND TAU AND ITS ROLE IN PRION-LIKE PROPAGATION OF TAU-PATHOLOGY IN VITRO AND IN VIVO.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P385, doi. 10.1016/j.jalz.2016.06.722
    By:
    • Vasconcelos, Bruno;
    • Stancu, Ilie-Cosmin;
    • Buist, Arjan;
    • Bird, Matthew;
    • Wang, Peng;
    • Vanoosthuyse, Alexandre;
    • Van Kolen, Kristof;
    • Verheyen, An;
    • Kienlen-Campard, Pascal;
    • Octave, Jean-Noël;
    • Baatsen, Peter;
    • Moechars, Diederik;
    • Dewachter, Ilse
    Publication type:
    Article
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