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On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF.
Published in:
BMC Structural Biology, 2009, v. 9, p. 1, doi. 10.1186/1472-6807-9-36
By:
- Meiying Zheng;
- Cierpicki, Tomasz;
- Ko Momotani;
- Artamonov, Mykhaylo V.;
- Derewenda, Urszula;
- Bushweller, John H.;
- Somlyo, Avril V.;
- Derewenda, Zygmunt S.
Publication type:
Article
RSK2 contributes to myogenic vasoconstriction of resistance arteries by activating smooth muscle myosin and the Na+/H+ exchanger.
Published in:
Science Signaling, 2018, v. 11, n. 554, p. 1, doi. 10.1126/scisignal.aar3924
By:
- Artamonov, Mykhaylo V.;
- Sonkusare, Swapnil K.;
- Good, Miranda E.;
- Momotani, Ko;
- Eto, Masumi;
- Isakson, Brant E.;
- Le, Thu H.;
- Cope, Eric L.;
- Derewenda, Zygmunt S.;
- Derewenda, Urszula;
- Somlyo, Avril V.
Publication type:
Article
The p90 Ribosomal S6 Kinase (RSK) Is a Mediator of Smooth Muscle Contractility.
Published in:
PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058703
By:
- Artamonov, Mykhaylo;
- Momotani, Ko;
- Utepbergenov, Darkhan;
- Franke, Aaron;
- Khromov, Alexander;
- Derewenda, Zygmunt S.;
- Somlyo, Avril V.
Publication type:
Article
The DC-module of doublecortin: Dynamics, domain boundaries, and functional implications.
Published in:
Proteins, 2006, v. 64, n. 4, p. 874, doi. 10.1002/prot.21068
By:
- Cierpicki, Tomasz;
- Kim, Myung Hee;
- Cooper, David R.;
- Derewenda, Urszula;
- Bushweller, John H.;
- Derewenda, Zygmunt S.
Publication type:
Article
B. subtilis ykuD protein at 2.0 Å resolution: Insights into the structure and function of a novel, ubiquitous family of bacterial enzymes.
Published in:
Proteins, 2006, v. 62, n. 1, p. 144, doi. 10.1002/prot.20702
By:
- Bielnicki, Jakub;
- Devedjiev, Yancho;
- Derewenda, Urszula;
- Dauter, Zbigniew;
- Joachimiak, Andrzej;
- Derewenda, Zygmunt S.
Publication type:
Article
Homologs of the α- and β-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome.
Published in:
Proteins, 2000, v. 39, n. 1, p. 1, doi. 10.1002/(SICI)1097-0134(20000401)39:1<1::AID-PROT1>3.0.CO;2-N
By:
- Sheffield, Peter J.;
- Garrard, Sarah;
- Caspi, Michal;
- Aoki, Junken;
- Arai, Hiroyuki;
- Derewenda, Urszula;
- Inoue, Keizo;
- Suter, Beat;
- Reiner, Orly;
- Derewenda, Zygmunt S.
Publication type:
Article
p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscle.
Published in:
Frontiers in Physiology, 2023, p. 1, doi. 10.3389/fphys.2023.1228488
By:
- Kalra, Jaspreet;
- Artamonov, Mykhaylo;
- Hua Wang;
- Frank, Aaron;
- Markowska, Zaneta;
- Li Jin;
- Derewenda, Zygmunt S.;
- Ayon, Ramon J.;
- Somlyo, Avril
Publication type:
Article
THE CHALLENGES OF DRUG DISCOVERY: DESIGN OF SELECTIVE JAK INHIBITORS FOR TREATMENT OF AUTOIMMUNE DISORDERS.
Published in:
Wiadomości Lekarskie, 2018, v. 71, n. 1, Part 1, p. 97
By:
- Derewenda, Zygmunt S.
Publication type:
Article
Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit.
Published in:
EMBO Journal, 2013, v. 32, n. 7, p. 1023, doi. 10.1038/emboj.2013.30
By:
- Yeh, Ting-Yu;
- Kowalska, Anna K;
- Scipioni, Brett R;
- Cheong, Frances Ka Yan;
- Zheng, Meiying;
- Derewenda, Urszula;
- Derewenda, Zygmunt S;
- Schroer, Trina A
Publication type:
Article
Preparation and crystal structure of the recombinant α1/α2 catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib.
Published in:
Protein Engineering, 2001, v. 14, n. 7, p. 513, doi. 10.1093/protein/14.7.513
By:
- Sheffield, Peter J.;
- McMullen, Todd W.P.;
- Li, Jia;
- Ho, Yew-Seng;
- Garrard, Sarah M.;
- Derewenda, Urszula;
- Derewenda, Zygmunt S.
Publication type:
Article
Crystallization and preliminary crystallographic studies of the precursor and mature forms of a neutral lipase from the fungus Rhizopus delemar.
Published in:
Proteins, 1994, v. 18, n. 3, p. 301, doi. 10.1002/prot.340180311
By:
- Swenson, Lora;
- Green, Ruth;
- Joerger, Rolf;
- Haas, Michael;
- Scott, Karen;
- Wei, Yunyi;
- Derewenda, Urszula;
- Lawson, David M.;
- Derewenda, Zygmunt S.
Publication type:
Article
A structural role for tryptophan in proteins, and the ubiquitous Trp Cδ1—H...O=C (backbone) hydrogen bond.
Published in:
Acta Crystallographica: Section D, Structural Biology, 2024, v. 80, n. 7, p. 551, doi. 10.1107/S2059798324005515
By:
- Szczygiel, Michal;
- Derewenda, Urszula;
- Scheiner, Steve;
- Minor, Wladek;
- Derewenda, Zygmunt S.
Publication type:
Article
Secret of Life: Rosalind Franklin, James Watson, Francis Crick, and the discovery of DNA's Double Helix. By Howard Markel. W. W. Norton & Co., 2021. Hardback, pp. 608. ISBN 978‐1324002239. Price USD 30.00.
Published in:
Acta Crystallographica: Section D, Structural Biology, 2022, v. 78, n. 12, p. 1469, doi. 10.1107/S2059798322010658
By:
- Derewenda, Zygmunt S.
Publication type:
Article
The structure of the C‐terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan‐specific synthetic Fab.
Published in:
Acta Crystallographica: Section D, Structural Biology, 2018, v. 74, n. 7, p. 681, doi. 10.1107/S2059798318007878
By:
- Radwańska, Malwina J.;
- Jaskółowski, Mateusz;
- Davydova, Elena;
- Derewenda, Urszula;
- Miyake, Tsuyoshi;
- Engel, Daniel A.;
- Kossiakoff, Anthony A.;
- Derewenda, Zygmunt S.
Publication type:
Article
Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.
Published in:
Acta Crystallographica: Section D, Structural Biology, 2017, v. 73, n. 9, p. 767, doi. 10.1107/S2059798317010737
By:
- Bukrejewska, Malgorzata;
- Derewenda, Urszula;
- Radwanska, Malwina;
- Engel, Daniel A.;
- Derewenda, Zygmunt S.
Publication type:
Article
Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.
Published in:
Acta Crystallographica: Section D, Structural Biology, 2016, v. 72, n. 1, p. 49, doi. 10.1107/S2059798315021439
By:
- Baker, Laura E.;
- Ellena, Jeffrey F.;
- Handing, Katarzyna B.;
- Derewenda, Urszula;
- Utepbergenov, Darkhan;
- Engel, Daniel A.;
- Derewenda, Zygmunt S.
Publication type:
Article
The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein.
Published in:
Journal of Cell Biology, 2011, v. 192, n. 3, p. 433
By:
- Żyłkiewicz, Eliza;
- Kijańska, Monika;
- Choi, Won-Chan;
- Derewenda, Urszula;
- Derewenda, Zygmunt S.;
- Stukenberg, P. Todd
Publication type:
Article
Abstractions, algorithms and data structures for structural bioinformatics in PyCogent.
Published in:
Journal of Applied Crystallography, 2011, v. 44, n. 2, p. 424, doi. 10.1107/S0021889811004481
By:
- Cieślik, Marcin;
- Derewenda, Zygmunt S.;
- Mura, Cameron
Publication type:
Article
Bacterial Expression, Purification and In Vitro Phosphorylation of Full-Length Ribosomal S6 Kinase 2 (RSK2).
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164343
By:
- Utepbergenov, Darkhan;
- Hennig, Paulina M.;
- Derewenda, Urszula;
- Artamonov, Mykhaylo V.;
- Somlyo, Avril V.;
- Derewenda, Zygmunt S.
Publication type:
Article
Crystal structure of the Escherichia coli thioesterase II, a homolog of the human Nef binding enzyme.
Published in:
Nature Structural Biology, 2000, v. 7, n. 7, p. 555
By:
- Li, Jia;
- Derewenda, Urszula;
- Dauter, Zbigniew;
- Smith, Stuart;
- Derewenda, Zygmunt S.
Publication type:
Article
The name is bond ? H bond.
Published in:
Nature Structural Biology, 1999, v. 6, n. 5, p. 403, doi. 10.1038/8195
By:
- Martin, T.W.;
- Derewenda, Zygmunt S.
Publication type:
Article
Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase.
Published in:
Nature Structural Biology, 1999, v. 6, n. 4, p. 340
By:
- Wei, Yunyi;
- Contreras, Juan Antonio;
- Sheffield, Peter;
- Osterlund, Torben;
- Derewenda, Urszula;
- Kneusel, R.E.;
- Matern, Ulrich;
- Holm, Cecilia;
- Derewenda, Zygmunt S.
Publication type:
Article
Structure of the gangrene α-toxin: the beauty in the beast.
Published in:
Nature Structural Biology, 1998, v. 5, n. 8, p. 659, doi. 10.1038/1351
By:
- Derewenda, Zygmunt S.;
- Martin, T.W.
Publication type:
Article
Letter to the Editor: Assignment of 1H, 13C and 15N resonances of the N-terminal microtubule-binding domain of human doublecortin.
Published in:
Journal of Biomolecular NMR, 2003, v. 25, n. 1, p. 81, doi. 10.1023/A:1021981207062
By:
- Cierpicki, Tomasz;
- Myung Hee Kim;
- Otlewski, Jacek;
- Derewenda, Zygmunt S.;
- Bushweller, John H.
Publication type:
Article
The DCX-domain tandems of doublecortin and doublecortin-like kinase.
Published in:
Nature Structural Biology, 2003, v. 10, n. 5, p. 324, doi. 10.1038/nsb918
By:
- Kim, Myung Hee;
- Cierpicki, Tomasz;
- Derewenda, Urszula;
- Krowarsch, Daniel;
- Feng, Yuanyi;
- Devedjiev, Yancho;
- Dauter, Zbigniew;
- Walsh, Christopher A.;
- Otlewski, Jacek;
- Bushweller, John H.;
- Derewenda, Zygmunt S.
Publication type:
Article
C─H⋯O hydrogen bonds in kinase‐inhibitor interfaces.
Published in:
IUBMB Life, 2020, v. 72, n. 6, p. 1233, doi. 10.1002/iub.2282
By:
- Derewenda, Zygmunt S.;
- Hawro, Izabela;
- Derewenda, Urszula
Publication type:
Article
The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.
Published in:
Protein Science: A Publication of the Protein Society, 2009, v. 18, n. 10, p. 2067, doi. 10.1002/pro.219
By:
- Cierpicki, Tomasz;
- Bielnicki, Jakub;
- Zheng, Meiying;
- Gruszczyk, Jakub;
- Kasterka, Marta;
- Petoukhov, Maxim;
- Zhang, Aming;
- Fernandez, Erik J.;
- Svergun, Dmitri I.;
- Derewenda, Urszula;
- Bushweller, John H.;
- Derewenda, Zygmunt S.
Publication type:
Article
Toward rational protein crystallization: A Web server for the design of crystallizable protein variants.
Published in:
Protein Science: A Publication of the Protein Society, 2007, v. 16, n. 8, p. 1569, doi. 10.1110/ps.072914007
By:
- Goldschmidt, Lukasz;
- Cooper, David R.;
- Derewenda, Zygmunt S.;
- Eisenberg, David
Publication type:
Article
Bivalent Peptides as Models for Multimeric Targets of PDZ Domains.
Published in:
ChemBioChem, 2007, v. 8, n. 4, p. 443, doi. 10.1002/cbic.200600389
By:
- Paduch, Marcin;
- Biernat, Monika;
- Stefanowicz, Piotr;
- Derewenda, Zygmunt S.;
- Szewczuk, Zbigniew;
- Otlewski, Jacek
Publication type:
Article

Found: 29

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF.

RSK2 contributes to myogenic vasoconstriction of resistance arteries by activating smooth muscle myosin and the Na<sup>+</sup>/H<sup>+</sup> exchanger.

The p90 Ribosomal S6 Kinase (RSK) Is a Mediator of Smooth Muscle Contractility.

The DC-module of doublecortin: Dynamics, domain boundaries, and functional implications.

B. subtilis ykuD protein at 2.0 Å resolution: Insights into the structure and function of a novel, ubiquitous family of bacterial enzymes.

Homologs of the α- and β-subunits of mammalian brain platelet-activating factor acetylhydrolase Ib in the Drosophila melanogaster genome.

p90RSK2, a new MLCK mediates contractility in myosin light chain kinase null smooth muscle.

THE CHALLENGES OF DRUG DISCOVERY: DESIGN OF SELECTIVE JAK INHIBITORS FOR TREATMENT OF AUTOIMMUNE DISORDERS.

Dynactin helps target Polo-like kinase 1 to kinetochores via its left-handed beta-helical p27 subunit.

Preparation and crystal structure of the recombinant α1/α2 catalytic heterodimer of bovine brain platelet-activating factor acetylhydrolase Ib.

Crystallization and preliminary crystallographic studies of the precursor and mature forms of a neutral lipase from the fungus Rhizopus delemar.

A structural role for tryptophan in proteins, and the ubiquitous Trp C<sup>δ1</sup>—H...O=C (backbone) hydrogen bond.

Secret of Life: Rosalind Franklin, James Watson, Francis Crick, and the discovery of DNA's Double Helix. By Howard Markel. W. W. Norton & Co., 2021. Hardback, pp. 608. ISBN 978‐1324002239. Price USD 30.00.

The structure of the C‐terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan‐specific synthetic Fab.

Crystal structures of the methyltransferase and helicase from the ZIKA 1947 MR766 Uganda strain.

Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses.

The N-terminal coiled-coil of Ndel1 is a regulated scaffold that recruits LIS1 to dynein.

Abstractions, algorithms and data structures for structural bioinformatics in PyCogent.

Bacterial Expression, Purification and In Vitro Phosphorylation of Full-Length Ribosomal S6 Kinase 2 (RSK2).

Crystal structure of the Escherichia coli thioesterase II, a homolog of the human Nef binding enzyme.

The name is bond ? H bond.

Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase.

Structure of the gangrene α-toxin: the beauty in the beast.

Letter to the Editor: Assignment of <sup>1</sup>H, <sup>13</sup>C and <sup>15</sup>N resonances of the N-terminal microtubule-binding domain of human doublecortin.

The DCX-domain tandems of doublecortin and doublecortin-like kinase.

C─H⋯O hydrogen bonds in kinase‐inhibitor interfaces.

The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.

Toward rational protein crystallization: A Web server for the design of crystallizable protein variants.

Bivalent Peptides as Models for Multimeric Targets of PDZ Domains.