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V2 hotspot optimized MVA vaccine expressing stabilized HIV-1 Clade C envelope Gp140 delays acquisition of heterologous Clade C Tier 2 challenges in Mamu-A*01 negative Rhesus Macaques.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.914969
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- Publication type:
- Article
Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth.
- Published in:
- PLoS Pathogens, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.ppat.1005989
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- Publication type:
- Article
Strong T<sub>H</sub>1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.
- Published in:
- Science Translational Medicine, 2019, v. 11, n. 519, p. 1, doi. 10.1126/scitranslmed.aav1800
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- Publication type:
- Article
Transmitted Virus Fitness and Host T Cell Responses Collectively Define Divergent Infection Outcomes in Two HIV-1 Recipients.
- Published in:
- PLoS Pathogens, 2015, v. 11, n. 1, p. 1, doi. 10.1371/journal.ppat.1004565
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- Publication type:
- Article
CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells.
- Published in:
- PLoS Pathogens, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.ppat.1004467
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- Publication type:
- Article
Target Cell Availability, Rather than Breast Milk Factors, Dictates Mother-to-Infant Transmission of SIV in Sooty Mangabeys and Rhesus Macaques.
- Published in:
- PLoS Pathogens, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.ppat.1003958
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- Publication type:
- Article
Viral Escape from Neutralizing Antibodies in Early Subtype A HIV-1 Infection Drives an Increase in Autologous Neutralization Breadth.
- Published in:
- PLoS Pathogens, 2013, v. 9, n. 2, p. 1, doi. 10.1371/journal.ppat.1003173
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- Publication type:
- Article
Role of Transmitted Gag CTL Polymorphisms in Defining Replicative Capacity and Early HIV-1 Pathogenesis.
- Published in:
- PLoS Pathogens, 2012, v. 8, n. 11, p. 1, doi. 10.1371/journal.ppat.1003041
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- Publication type:
- Article
Expanding the toolbox of metabolically stable lipid prodrug strategies.
- Published in:
- Frontiers in Pharmacology, 2023, v. 13, p. 1, doi. 10.3389/fphar.2022.1083284
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- Publication type:
- Article
VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120.
- Published in:
- Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2018.03163
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- Publication type:
- Article
Infection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes.
- Published in:
- Retrovirology, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12977-015-0176-2
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- Publication type:
- Article
Infection of ectocervical tissue and universal targeting of T‑cells mediated by primary non‑macrophage‑tropic and highly macrophage‑tropic HIV‑1 R5 envelopes
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- Retrovirology, 2015, v. 12, n. 1, p. 48, doi. 10.1186/s12977-015-0176-2
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- Publication type:
- Article
HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages.
- Published in:
- Retrovirology, 2015, v. 12, n. 1, p. 1, doi. 10.1186/s12977-015-0141-0
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- Publication type:
- Article
Decreased plasticity of coreceptor use by CD4-independent SIV Envs that emerge in vivo.
- Published in:
- Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-133
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- Publication type:
- Article
HIV-1 subtype C superinfected individuals mount low autologous neutralizing antibody responses prior to intrasubtype superinfection.
- Published in:
- Retrovirology, 2012, v. 9, n. 1, p. 76, doi. 10.1186/1742-4690-9-76
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- Publication type:
- Article
Effect of Glycosylation on an Immunodominant Region in the V1V2 Variable Domain of the HIV-1 Envelope gp120 Protein.
- Published in:
- PLoS Computational Biology, 2016, v. 12, n. 10, p. 1, doi. 10.1371/journal.pcbi.1005094
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- Publication type:
- Article
The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.
- Published in:
- PLoS Pathogens, 2021, v. 17, n. 2, p. 1, doi. 10.1371/journal.ppat.1009257
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- Publication type:
- Article
A Mechanistic Understanding of Allosteric Immune Escape Pathways in the HIV-1 Envelope Glycoprotein
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- PLoS Computational Biology, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.pcbi.1003046
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- Publication type:
- Article
High throughput analysis of B cell dynamics and neutralizing antibody development during immunization with a novel clade C HIV-1 envelope.
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- PLoS Pathogens, 2023, v. 19, n. 10, p. 1, doi. 10.1371/journal.ppat.1011717
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- Publication type:
- Article
Early T follicular helper cell activity accelerates hepatitis C virus-specific B cell expansion.
- Published in:
- 2021
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- Publication type:
- journal article
Striking a balance in an antibody network: A roadmap for HIV-1 vaccines.
- Published in:
- 2019
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- Publication type:
- journal article
A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques.
- Published in:
- Science Immunology, 2022, v. 7, n. 73, p. 1, doi. 10.1126/sciimmunol.abl4102
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- Publication type:
- Article
A pathway to HIV-1 neutralization breadth.
- Published in:
- Nature Medicine, 2015, v. 21, n. 11, p. 1246, doi. 10.1038/nm.3989
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- Publication type:
- Article
Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART.
- Published in:
- PLoS Pathogens, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.ppat.1009825
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- Publication type:
- Article
Evaluation of Distinct Blood Lymphocyte Populations in Human Immunodeficiency Virus Type 1-Infected Subjects in the Absence or Presence of Effective Therapy.
- Published in:
- Journal of Infectious Diseases, 1999, v. 180, n. 6, p. 1851, doi. 10.1086/315117
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- Publication type:
- Article
Escape from Autologous Neutralizing Antibodies in Acute/Early Subtype C HIV-1 Infection Requires Multiple Pathways.
- Published in:
- PLoS Pathogens, 2009, v. 5, n. 9, p. 1, doi. 10.1371/journal.ppat.1000594
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- Publication type:
- Article
Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1.
- Published in:
- PLoS Pathogens, 2009, v. 5, n. 1, p. 1, doi. 10.1371/journal.ppat.1000274
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- Publication type:
- Article