Works by Denning, Chris

Results: 44

Rapid micropatterning of cell lines and human pluripotent stem cells on elastomeric membranes.

Published in:

Biotechnology & Bioengineering, 2012, v. 109, n. 10, p. 2630, doi. 10.1002/bit.24529

By:

Paik, Isha;
Scurr, David J.;
Morris, Bryan;
Hall, Graham;
Denning, Chris;
Alexander, Morgan R.;
Shakesheff, Kevin M.;
Dixon, James E.

Publication type:

Article

Maintenance of pluripotency in human embryonic stem cells cultured on a synthetic substrate in conditioned medium.

Published in:

Biotechnology & Bioengineering, 2010, v. 105, n. 1, p. 130, doi. 10.1002/bit.22520

By:

Mahlstedt, Magdalena M.;
Anderson, David;
Sharp, James S.;
McGilvray, Roger;
Barbadillo Muñoz, Maria D.;
Buttery, Lee D.;
Alexander, Morgan R.;
Rose, Felicity R.A.J.;
Denning, Chris

Publication type:

Article

Automated, scalable culture of human embryonic stem cells in feeder-free conditions.

Published in:

Biotechnology & Bioengineering, 2009, v. 102, n. 6, p. 1636, doi. 10.1002/bit.22187

By:

Thomas, Rob J.;
Anderson, David;
Chandra, Amit;
Smith, Nigel M.;
Young, Lorraine E.;
Williams, David;
Denning, Chris

Publication type:

Article

Mitochondrial DNA: Hotspot for Potential Gene Modifiers Regulating Hypertrophic Cardiomyopathy.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 8, p. 2349, doi. 10.3390/jcm9082349

By:

Kargaran, Parisa K.;
Evans, Jared M.;
Bodbin, Sara E.;
Smith, James G. W.;
Nelson, Timothy J.;
Denning, Chris;
Mosqueira, Diogo

Publication type:

Article

Genome-edited Human Pluripotent Stem Cells (hPSCs) To Study The Functionality Of β<sub>2</sub>-adrenergic Receptor Polymorphisms.

Published in:

Malaysian Journal of Medicine & Health Sciences, 2022, v. 18, p. 42

By:

Nasim Mohd Yusof, Nurul Ain;
Kondrashov, Alexander;
Goulding, Joëlle;
Hoang, Minh Duc;
Vo, Nguyen;
Guerout, Yorick;
Denning, Chris

Publication type:

Article

The patentability of human embryonic stem cells in Europe.

Published in:

Nature Biotechnology, 2006, v. 24, n. 6, p. 653, doi. 10.1038/nbt0606-653

By:

Porter, Gerard;
Denning, Chris;
Plomer, Aurora;
Sinden, John;
Torremans, Paul

Publication type:

Article

Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes.

Published in:

European Heart Journal, 2014, v. 35, n. 16, p. 1078, doi. 10.1093/eurheartj/eht067

By:

Matsa, Elena;
Dixon, James E.;
Medway, Christopher;
Georgiou, Orestis;
Patel, Minal J.;
Morgan, Kevin;
Kemp, Paul J.;
Staniforth, Andrew;
Mellor, Ian;
Denning, Chris

Publication type:

Article

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation.

Published in:

European Heart Journal, 2011, v. 32, n. 8, p. 952, doi. 10.1093/eurheartj/ehr073

By:

Matsa, Elena;
Rajamohan, Divya;
Dick, Emily;
Young, Lorraine;
Mellor, Ian;
Staniforth, Andrew;
Denning, Chris

Publication type:

Article

The use of fluorescence correlation spectroscopy to monitor cell surface β2-adrenoceptors at low expression levels in human embryonic stem cell-derived cardiomyocytes and fibroblasts.

Published in:

FASEB Journal, 2021, v. 35, n. 4, p. 1, doi. 10.1096/fj.202002268R

By:

Goulding, Joëlle;
Kondrashov, Alexander;
Mistry, Sarah J.;
Melarangi, Tony;
Vo, Nguyen T. N.;
Hoang, Duc M.;
White, Carl W.;
Denning, Chris;
Briddon, Stephen J.;
Hill, Stephen J.

Publication type:

Article

A Qualitative Evaluation of the Barriers and Enablers for Implementation of an Asymptomatic SARS-CoV-2 Testing Service at the University of Nottingham: A Multi-Site Higher Education Setting in England.

Published in:

International Journal of Environmental Research & Public Health, 2022, v. 19, n. 20, p. 13140, doi. 10.3390/ijerph192013140

By:

Blake, Holly;
Somerset, Sarah;
Mahmood, Ikra;
Mahmood, Neelam;
Corner, Jessica;
Ball, Jonathan K.;
Denning, Chris

Publication type:

Article

Workforce Experiences of a Rapidly Established SARS-CoV-2 Asymptomatic Testing Service in a Higher Education Setting: A Qualitative Study.

Published in:

International Journal of Environmental Research & Public Health, 2022, v. 19, n. 19, p. 12464, doi. 10.3390/ijerph191912464

By:

Blake, Holly;
Somerset, Sarah;
Mahmood, Ikra;
Mahmood, Neelam;
Corner, Jessica;
Ball, Jonathan K.;
Denning, Chris

Publication type:

Article

Exploring the Psychological Impacts of COVID-19 Social Restrictions on International University Students: A Qualitative Study.

Published in:

International Journal of Environmental Research & Public Health, 2022, v. 19, n. 13, p. 7631, doi. 10.3390/ijerph19137631

By:

Al-Oraibi, Amani;
Fothergill, Lauren;
Yildirim, Mehmet;
Knight, Holly;
Carlisle, Sophie;
O'Connor, Mórna;
Briggs, Lydia;
Morling, Joanne R.;
Corner, Jessica;
Ball, Jonathan K.;
Denning, Chris;
Vedhara, Kavita;
Blake, Holly

Publication type:

Article

Impacts of the COVID-19 Pandemic and Self-Isolation on Students and Staff in Higher Education: A Qualitative Study.

Published in:

International Journal of Environmental Research & Public Health, 2021, v. 18, n. 20, p. 10675, doi. 10.3390/ijerph182010675

By:

Knight, Holly;
Carlisle, Sophie;
O'Connor, Mórna;
Briggs, Lydia;
Fothergill, Lauren;
Al-Oraibi, Amani;
Yildirim, Mehmet;
Morling, Joanne R.;
Corner, Jessica;
Ball, Jonathan;
Denning, Chris;
Vedhara, Kavita;
Blake, Holly

Publication type:

Article

Students' Views towards Sars-Cov-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study.

Published in:

International Journal of Environmental Research & Public Health, 2021, v. 18, n. 8, p. 4182, doi. 10.3390/ijerph18084182

By:

Blake, Holly;
Knight, Holly;
Jia, Ru;
Corner, Jessica;
Morling, Joanne R.;
Denning, Chris;
Ball, Jonathan K.;
Bolton, Kirsty;
Figueredo, Grazziela;
Morris, David E.;
Tighe, Patrick;
Villalon, Armando Mendez;
Ayling, Kieran;
Vedhara, Kavita

Publication type:

Article

Direct RT-qPCR Assay for the Detection of SARS-CoV-2 in Saliva Samples.

Published in:

Methods & Protocols, 2022, v. 5, n. 2, p. N.PAG, doi. 10.3390/mps5020025

By:

Tarantini, Francesco Saverio;
Wu, Siyu;
Jenkins, Harry;
Tellechea Lopez, Ana;
Tomlin, Hannah;
Hyde, Ralph;
Lis-Slimak, Katarzyna;
Thompson, Jamie Louise;
Pijuan-Galitó, Sara;
Scales, Danielle;
Kaneko, Kazuyo;
Dey, Jayasree;
Park, Emily;
Hill, Jack;
Lee, I-Ning;
Doolan, Lara;
Arendt-Tranholm, Asta;
Denning, Chris;
Seedhouse, Claire;
Benest, Andrew V.

Publication type:

Article

Basic Research Approaches to Evaluate Cardiac Arrhythmia in Heart Failure and Beyond.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.806366

By:

Cumberland, Max J.;
Riebel, Leto L.;
Roy, Ashwin;
O'Shea, Christopher;
Holmes, Andrew P.;
Denning, Chris;
Kirchhof, Paulus;
Rodriguez, Blanca;
Gehmlich, Katja

Publication type:

Article

Advancing cancer therapy with custom-built alternating electric field devices.

Published in:

Bioelectronic Medicine, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s42234-024-00164-3

By:

Jobson, Isobel;
Vo, Nguyen T. N.;
Kujawinski, Edward;
Denning, Chris;
Stolnik, Snow;
Chauhan, Veeren M.;
Rawson, Frankie

Publication type:

Article

Multifunctional Bioinstructive 3D Architectures to Modulate Cellular Behavior.

Published in:

Advanced Functional Materials, 2019, v. 29, n. 38, p. N.PAG, doi. 10.1002/adfm.201902016

By:

Vaithilingam, Jayasheelan;
Sanjuan‐Alberte, Paola;
Campora, Simona;
Rance, Graham A.;
Jiang, Long;
Thorpe, Jordan;
Burroughs, Laurence;
Tuck, Christopher J.;
Denning, Chris;
Wildman, Ricky D.;
Hague, Richard J. M.;
Alexander, Morgan R.;
Rawson, Frankie J.

Publication type:

Article

Characterisation of the invasive tumour niche using astrocyte-glioblastoma organoids and decellularised human brain.

Published in:

Neuro-Oncology, 2019, v. 21, p. 7, doi. 10.1093/neuonc/noz167.028

By:

Diksin, Mohammed;
Rowlinson, Jonathan;
Kondrashov, Alexandar;
Denning, Chris;
Hughes, Jamie;
Constantin-Teodo, Tim;
Cui, Wei;
Gell, Chris;
Onion, David;
Croxall, Nicola;
Smith, Stuart;
Rahman, Ruman

Publication type:

Article

Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome.

Published in:

Human Molecular Genetics, 2007, v. 16, n. 10, p. 1253, doi. 10.1093/hmg/ddm074

By:

Allegrucci, Cinzia;
Wu, Yue-Zhong;
Thurston, Alexandra;
Denning, Chris N.;
Priddle, Helen;
Mummery, Christine L.;
Ward-van Oostwaard, Dorien;
Andrews, Peter W.;
Stojkovic, Miodrag;
Smith, Nigel;
Parkin, Tony;
Jones, Mark Edmondson;
Warren, Graham;
Yu, Li;
Brena, Romulo Martin;
Plass, Christoph;
Young, Lorraine E.

Publication type:

Article

Derivation and characterisation of the human embryonic stem cell lines, NOTT1 and NOTT2.

Published in:

In Vitro Cellular & Developmental Biology Animal, 2010, v. 46, n. 3/4, p. 367, doi. 10.1007/s11626-010-9290-6

By:

Priddle, Helen;
Allegrucci, Cinzia;
Burridge, Paul;
Munoz, Maria;
Smith, Nigel;
Devlin, Lyndsey;
Sjoblom, Cecilia;
Chamberlain, Sarah;
Watson, Sue;
Young, Lorraine;
Denning, Chris

Publication type:

Article

Complex Relationship Between Cardiac Fibroblasts and Cardiomyocytes in Health and Disease.

Published in:

2021

By:

Hall, Caitlin;
Gehmlich, Katja;
Denning, Chris;
Pavlovic, Davor

Publication type:

journal article

Current status of drug screening and disease modelling in human pluripotent stem cells.

Published in:

BioEssays, 2013, v. 35, n. 3, p. 281, doi. 10.1002/bies.201200053

By:

Rajamohan, Divya;
Matsa, Elena;
Kalra, Spandan;
Crutchley, James;
Patel, Asha;
George, Vinoj;
Denning, Chris

Publication type:

Article

Correction: A secreted proteomic footprint for stem cell pluripotency.

Published in:

2025

By:

Lewis, Philip A.;
Silajdžić, Edina;
Smith, Helen;
Bates, Nicola;
Smith, Christopher A.;
Mancini, Fabrizio E.;
Knight, David;
Denning, Chris;
Brison, Daniel R.;
Kimber, Susan J.

Publication type:

Correction Notice

Materials for stem cell factories of the future.

Published in:

Nature Materials, 2014, v. 13, n. 6, p. 570, doi. 10.1038/nmat3972

By:

Celiz, Adam D.;
Smith, James G. W.;
Langer, Robert;
Anderson, Daniel G.;
Winkler, David A.;
Barrett, David A.;
Davies, Martyn C.;
Young, Lorraine E.;
Denning, Chris;
Alexander, Morgan R.

Publication type:

Article

Directed Differentiation of Human Embryonic Stem Cells to Interrogate the Cardiac Gene Regulatory Network.

Published in:

Molecular Therapy, 2011, v. 19, n. 9, p. 1695, doi. 10.1038/mt.2011.125

By:

Dixon, James E.;
Dick, Emily;
Rajamohan, Divya;
Shakesheff, Kevin M.;
Denning, Chris

Publication type:

Article

Transgenic Enrichment of Cardiomyocytes From Human Embryonic Stem Cells.

Published in:

Molecular Therapy, 2007, v. 15, n. 11, p. 2027, doi. 10.1038/sj.mt.6300303

By:

Anderson, David;
Self, Tim;
Mellor, Ian R.;
Goh, Gareth;
Hill, Stephen J.;
Denning, Chris

Publication type:

Article

Development and validation of broad-spectrum magnetic particle labelling processes for cell therapy manufacturing.

Published in:

Stem Cell Research & Therapy, 2018, v. 9, n. 1, p. N.PAG, doi. 10.1186/s13287-018-0968-0

By:

Harrison, Richard;
Lugo Leija, Hilda Anaid;
Strohbuecker, Stephanie;
Crutchley, James;
Marsh, Sarah;
Denning, Chris;
El Haj, Alicia;
Sottile, Virginie

Publication type:

Article

Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39369-y

By:

Hall, Caitlin;
Law, Jonathan P.;
Reyat, Jasmeet S.;
Cumberland, Max J.;
Hang, Shaun;
Vo, Nguyen T. N.;
Raniga, Kavita;
Weston, Chris J.;
O'Shea, Christopher;
Townend, Jonathan N.;
Gehmlich, Katja;
Ferro, Charles J.;
Denning, Chris;
Pavlovic, Davor

Publication type:

Article

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D.

Published in:

Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00259

By:

Zhou, Xin;
Bueno-Orovio, Alfonso;
Schilling, Richard J.;
Kirkby, Claire;
Denning, Chris;
Rajamohan, Divya;
Burrage, Kevin;
Tinker, Andrew;
Rodriguez, Blanca;
Harmer, Stephen C.

Publication type:

Article

A secreted proteomic footprint for stem cell pluripotency.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0299365

By:

Lewis, Philip A.;
Silajdžić, Edina;
Smith, Helen;
Bates, Nicola;
Smith, Christopher A.;
Mancini, Fabrizio E.;
Knight, David;
Denning, Chris;
Brison, Daniel R.;
Kimber, Susan J.

Publication type:

Article

Relationship Between Anxiety, Depression, and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Proof of Concept.

Published in:

Journal of Infectious Diseases, 2022, v. 225, n. 12, p. 2137, doi. 10.1093/infdis/jiac006

By:

Vedhara, Kavita;
Ayling, Kieran;
Jia, Ru;
Fairclough, Lucy;
Morling, Joanne R;
Ball, Jonathan K;
Knight, Holly;
Blake, Holly;
Corner, Jessica;
Denning, Chris;
Bolton, Kirsty;
Jackson, Hannah;
Coupland, Carol;
Tighe, Patrick

Publication type:

Article

Improved genetic manipulation of human embryonic stem cells.

Published in:

Nature Methods, 2008, v. 5, n. 5, p. 389, doi. 10.1038/nmeth.1200

By:

Braam, Stefan R.;
Denning, Chris;
Van Den Brink, Stieneke;
Kats, Peter;
Hochstenbach, Ron;
Passier, Robert;
Mummery, Christine L.

Publication type:

Article

Toward label-free Raman-activated cell sorting of cardiomyocytes derived from human embryonic stem cells.

Published in:

Journal of Biomedical Optics, 2011, v. 16, n. 4, p. 045002, doi. 10.1117/1.3570302

By:

Flavius C. Pascut;
Huey T. Goh;
Vinoj George;
Chris Denning;
Ioan Notingher

Publication type:

Article

Biomaterials Discovery: Discovery of a Novel Polymer for Xeno‐Free, Long‐Term Culture of Human Pluripotent Stem Cell Expansion (Adv. Healthcare Mater. 6/2021).

Published in:

Advanced Healthcare Materials, 2021, v. 10, n. 6, p. 1, doi. 10.1002/adhm.202170019

By:

Nasir, Aishah;
Thorpe, Jordan;
Burroughs, Laurence;
Meurs, Joris;
Pijuan‐Galito, Sara;
Irvine, Derek J.;
Alexander, Morgan R.;
Denning, Chris

Publication type:

Article

Discovery of a Novel Polymer for Xeno‐Free, Long‐Term Culture of Human Pluripotent Stem Cell Expansion.

Published in:

Advanced Healthcare Materials, 2021, v. 10, n. 6, p. 1, doi. 10.1002/adhm.202001448

By:

Nasir, Aishah;
Thorpe, Jordan;
Burroughs, Laurence;
Meurs, Joris;
Pijuan‐Galito, Sara;
Irvine, Derek J.;
Alexander, Morgan R.;
Denning, Chris

Publication type:

Article

Proliferative lifespan is conserved after nuclear transfer.

Published in:

Nature Cell Biology, 2003, v. 5, n. 6, p. 535, doi. 10.1038/ncb992

By:

Clark, A. John;
Ferrier, Patricia;
Aslam, Samena;
Burl, Sarah;
Denning, Chris;
Wylie, Diana;
Ross, Arlene;
de Sousa, Paul;
Wilmut, Ian;
Cui, Wei

Publication type:

Article

Improved Human Embryonic Stem Cell Embryoid Body Homogeneity and Cardiomyocyte Differentiation from a Novel V-96 Plate Aggregation System Highlights Interline Variability.

Published in:

Stem Cells, 2007, v. 25, n. 4, p. 929, doi. 10.1634/stemcells.2006-0598

By:

Burridge, Paul W.;
Anderson, David;
Priddle, Helen;
Muñoz, Maria D. Barbadillo;
Chamberlain, Sarah;
Allegrucci, Cinzia;
Young, Lorraine E.;
Denning, Chris

Publication type:

Article

Computer Vision for Substrate Detection in High‐Throughput Biomaterial Screens Using Bright‐Field Microscopy.

Published in:

Advanced Intelligent Systems (2640-4567), 2025, v. 7, n. 5, p. 1, doi. 10.1002/aisy.202400573

By:

Owen, Robert;
Nasir, Aishah;
Amer, Mahetab H.;
Nie, Chenxue;
Xue, Xuan;
Burroughs, Laurence;
Denning, Chris;
Wildman, Ricky D.;
Khan, Faraz A.;
Alexander, Morgan R.;
Rose, Felicity R. A. J.

Publication type:

Article

Quantifiable correlation of ToF‐SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content.

Published in:

Surface & Interface Analysis: SIA, 2022, v. 54, n. 4, p. 417, doi. 10.1002/sia.7052

By:

Taylor, Michael;
Simoes, Fabio;
Smith, James;
Genapathy, Sivaneswary;
Canning, Anne;
Lledos, Marina;
Chan, Weng C.;
Denning, Chris;
Scurr, David J.;
Steven, Rory T.;
Spencer, Steve J.;
Shard, Alexander G.;
Alexander, Morgan R.;
Zelzer, Mischa

Publication type:

Article

Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation.

Published in:

Advanced Materials, 2015, v. 27, n. 27, p. 4006, doi. 10.1002/adma.201501351

By:

Celiz, Adam D.;
Smith, James G. W.;
Patel, Asha K.;
Hook, Andrew L.;
Rajamohan, Divya;
George, Vinoj T.;
Flatt, Luke;
Patel, Minal J.;
Epa, Vidana C.;
Singh, Taranjit;
Langer, Robert;
Anderson, Daniel G.;
Allen, Nicholas D.;
Hay, David C.;
Winkler, David A.;
Barrett, David A.;
Davies, Martyn C.;
Young, Lorraine E.;
Denning, Chris;
Alexander, Morgan R.

Publication type:

Article

Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12354-8

By:

van Meer, Berend J.;
Krotenberg, Ana;
Sala, Luca;
Davis, Richard P.;
Eschenhagen, Thomas;
Denning, Chris;
Tertoolen, Leon G. J.;
Mummery, Christine L.

Publication type:

Article

Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification.

Published in:

Epigenetics, 2017, v. 12, n. 4, p. 277, doi. 10.1080/15592294.2017.1292189

By:

Lewis, Lara C.;
Lo, Peggy Cho Kiu;
Foster, Jeremy M.;
Dai, Nan;
Corrêa, Ivan R.;
Durczak, Paulina M.;
Duncan, Gary;
Ramsawhook, Ashley;
Aithal, Guruprasad Padur;
Denning, Chris;
Hannan, Nicholas R. F.;
Ruzov, Alexey

Publication type:

Article

5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development.

Published in:

Epigenetics, 2012, v. 7, n. 4, p. 383, doi. 10.4161/epi.19375

By:

Almeida, Rimple D.;
Loose, Matthew;
Sottile, Virginie;
Matsa, Elena;
Denning, Chris;
Young, Lorraine;
Johnson, Andrew D.;
Gering, Martin;
Ruzov, Alexey

Publication type:

Article