Works by Denning, Chris

Results: 43

Genome-edited Human Pluripotent Stem Cells (hPSCs) To Study The Functionality Of β<sub>2</sub>-adrenergic Receptor Polymorphisms.
Published in:
Malaysian Journal of Medicine & Health Sciences, 2022, v. 18, p. 42
By:
- Nasim Mohd Yusof, Nurul Ain;
- Kondrashov, Alexander;
- Goulding, Joëlle;
- Hoang, Minh Duc;
- Vo, Nguyen;
- Guerout, Yorick;
- Denning, Chris
Publication type:
Article
Basic Research Approaches to Evaluate Cardiac Arrhythmia in Heart Failure and Beyond.
Published in:
Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.806366
By:
- Cumberland, Max J.;
- Riebel, Leto L.;
- Roy, Ashwin;
- O'Shea, Christopher;
- Holmes, Andrew P.;
- Denning, Chris;
- Kirchhof, Paulus;
- Rodriguez, Blanca;
- Gehmlich, Katja
Publication type:
Article
The patentability of human embryonic stem cells in Europe.
Published in:
Nature Biotechnology, 2006, v. 24, n. 6, p. 653, doi. 10.1038/nbt0606-653
By:
- Porter, Gerard;
- Denning, Chris;
- Plomer, Aurora;
- Sinden, John;
- Torremans, Paul
Publication type:
Article
Relationship Between Anxiety, Depression, and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Proof of Concept.
Published in:
Journal of Infectious Diseases, 2022, v. 225, n. 12, p. 2137, doi. 10.1093/infdis/jiac006
By:
- Vedhara, Kavita;
- Ayling, Kieran;
- Jia, Ru;
- Fairclough, Lucy;
- Morling, Joanne R;
- Ball, Jonathan K;
- Knight, Holly;
- Blake, Holly;
- Corner, Jessica;
- Denning, Chris;
- Bolton, Kirsty;
- Jackson, Hannah;
- Coupland, Carol;
- Tighe, Patrick
Publication type:
Article
Improved genetic manipulation of human embryonic stem cells.
Published in:
Nature Methods, 2008, v. 5, n. 5, p. 389, doi. 10.1038/nmeth.1200
By:
- Braam, Stefan R.;
- Denning, Chris;
- Van Den Brink, Stieneke;
- Kats, Peter;
- Hochstenbach, Ron;
- Passier, Robert;
- Mummery, Christine L.
Publication type:
Article
Rapid micropatterning of cell lines and human pluripotent stem cells on elastomeric membranes.
Published in:
Biotechnology & Bioengineering, 2012, v. 109, n. 10, p. 2630, doi. 10.1002/bit.24529
By:
- Paik, Isha;
- Scurr, David J.;
- Morris, Bryan;
- Hall, Graham;
- Denning, Chris;
- Alexander, Morgan R.;
- Shakesheff, Kevin M.;
- Dixon, James E.
Publication type:
Article
Maintenance of pluripotency in human embryonic stem cells cultured on a synthetic substrate in conditioned medium.
Published in:
Biotechnology & Bioengineering, 2010, v. 105, n. 1, p. 130, doi. 10.1002/bit.22520
By:
- Mahlstedt, Magdalena M.;
- Anderson, David;
- Sharp, James S.;
- McGilvray, Roger;
- Barbadillo Muñoz, Maria D.;
- Buttery, Lee D.;
- Alexander, Morgan R.;
- Rose, Felicity R.A.J.;
- Denning, Chris
Publication type:
Article
Automated, scalable culture of human embryonic stem cells in feeder-free conditions.
Published in:
Biotechnology & Bioengineering, 2009, v. 102, n. 6, p. 1636, doi. 10.1002/bit.22187
By:
- Thomas, Rob J.;
- Anderson, David;
- Chandra, Amit;
- Smith, Nigel M.;
- Young, Lorraine E.;
- Williams, David;
- Denning, Chris
Publication type:
Article
Mitochondrial DNA: Hotspot for Potential Gene Modifiers Regulating Hypertrophic Cardiomyopathy.
Published in:
Journal of Clinical Medicine, 2020, v. 9, n. 8, p. 2349, doi. 10.3390/jcm9082349
By:
- Kargaran, Parisa K.;
- Evans, Jared M.;
- Bodbin, Sara E.;
- Smith, James G. W.;
- Nelson, Timothy J.;
- Denning, Chris;
- Mosqueira, Diogo
Publication type:
Article
Development and validation of broad-spectrum magnetic particle labelling processes for cell therapy manufacturing.
Published in:
Stem Cell Research & Therapy, 2018, v. 9, n. 1, p. N.PAG, doi. 10.1186/s13287-018-0968-0
By:
- Harrison, Richard;
- Lugo Leija, Hilda Anaid;
- Strohbuecker, Stephanie;
- Crutchley, James;
- Marsh, Sarah;
- Denning, Chris;
- El Haj, Alicia;
- Sottile, Virginie
Publication type:
Article
Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation.
Published in:
Advanced Materials, 2015, v. 27, n. 27, p. 4006, doi. 10.1002/adma.201501351
By:
- Celiz, Adam D.;
- Smith, James G. W.;
- Patel, Asha K.;
- Hook, Andrew L.;
- Rajamohan, Divya;
- George, Vinoj T.;
- Flatt, Luke;
- Patel, Minal J.;
- Epa, Vidana C.;
- Singh, Taranjit;
- Langer, Robert;
- Anderson, Daniel G.;
- Allen, Nicholas D.;
- Hay, David C.;
- Winkler, David A.;
- Barrett, David A.;
- Davies, Martyn C.;
- Young, Lorraine E.;
- Denning, Chris;
- Alexander, Morgan R.
Publication type:
Article
Advancing cancer therapy with custom-built alternating electric field devices.
Published in:
Bioelectronic Medicine, 2025, v. 11, n. 1, p. 1, doi. 10.1186/s42234-024-00164-3
By:
- Jobson, Isobel;
- Vo, Nguyen T. N.;
- Kujawinski, Edward;
- Denning, Chris;
- Stolnik, Snow;
- Chauhan, Veeren M.;
- Rawson, Frankie
Publication type:
Article
Chronic activation of human cardiac fibroblasts in vitro attenuates the reversibility of the myofibroblast phenotype.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39369-y
By:
- Hall, Caitlin;
- Law, Jonathan P.;
- Reyat, Jasmeet S.;
- Cumberland, Max J.;
- Hang, Shaun;
- Vo, Nguyen T. N.;
- Raniga, Kavita;
- Weston, Chris J.;
- O'Shea, Christopher;
- Townend, Jonathan N.;
- Gehmlich, Katja;
- Ferro, Charles J.;
- Denning, Chris;
- Pavlovic, Davor
Publication type:
Article
Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome.
Published in:
Human Molecular Genetics, 2007, v. 16, n. 10, p. 1253, doi. 10.1093/hmg/ddm074
By:
- Allegrucci, Cinzia;
- Wu, Yue-Zhong;
- Thurston, Alexandra;
- Denning, Chris N.;
- Priddle, Helen;
- Mummery, Christine L.;
- Ward-van Oostwaard, Dorien;
- Andrews, Peter W.;
- Stojkovic, Miodrag;
- Smith, Nigel;
- Parkin, Tony;
- Jones, Mark Edmondson;
- Warren, Graham;
- Yu, Li;
- Brena, Romulo Martin;
- Plass, Christoph;
- Young, Lorraine E.
Publication type:
Article
Current status of drug screening and disease modelling in human pluripotent stem cells.
Published in:
BioEssays, 2013, v. 35, n. 3, p. 281, doi. 10.1002/bies.201200053
By:
- Rajamohan, Divya;
- Matsa, Elena;
- Kalra, Spandan;
- Crutchley, James;
- Patel, Asha;
- George, Vinoj;
- Denning, Chris
Publication type:
Article
Correction: A secreted proteomic footprint for stem cell pluripotency.
Published in:
2025
By:
- Lewis, Philip A.;
- Silajdžić, Edina;
- Smith, Helen;
- Bates, Nicola;
- Smith, Christopher A.;
- Mancini, Fabrizio E.;
- Knight, David;
- Denning, Chris;
- Brison, Daniel R.;
- Kimber, Susan J.
Publication type:
Correction Notice
A secreted proteomic footprint for stem cell pluripotency.
Published in:
PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0299365
By:
- Lewis, Philip A.;
- Silajdžić, Edina;
- Smith, Helen;
- Bates, Nicola;
- Smith, Christopher A.;
- Mancini, Fabrizio E.;
- Knight, David;
- Denning, Chris;
- Brison, Daniel R.;
- Kimber, Susan J.
Publication type:
Article
Multifunctional Bioinstructive 3D Architectures to Modulate Cellular Behavior.
Published in:
Advanced Functional Materials, 2019, v. 29, n. 38, p. N.PAG, doi. 10.1002/adfm.201902016
By:
- Vaithilingam, Jayasheelan;
- Sanjuan‐Alberte, Paola;
- Campora, Simona;
- Rance, Graham A.;
- Jiang, Long;
- Thorpe, Jordan;
- Burroughs, Laurence;
- Tuck, Christopher J.;
- Denning, Chris;
- Wildman, Ricky D.;
- Hague, Richard J. M.;
- Alexander, Morgan R.;
- Rawson, Frankie J.
Publication type:
Article
Exploring the Psychological Impacts of COVID-19 Social Restrictions on International University Students: A Qualitative Study.
Published in:
International Journal of Environmental Research & Public Health, 2022, v. 19, n. 13, p. 7631, doi. 10.3390/ijerph19137631
By:
- Al-Oraibi, Amani;
- Fothergill, Lauren;
- Yildirim, Mehmet;
- Knight, Holly;
- Carlisle, Sophie;
- O'Connor, Mórna;
- Briggs, Lydia;
- Morling, Joanne R.;
- Corner, Jessica;
- Ball, Jonathan K.;
- Denning, Chris;
- Vedhara, Kavita;
- Blake, Holly
Publication type:
Article
Impacts of the COVID-19 Pandemic and Self-Isolation on Students and Staff in Higher Education: A Qualitative Study.
Published in:
International Journal of Environmental Research & Public Health, 2021, v. 18, n. 20, p. 10675, doi. 10.3390/ijerph182010675
By:
- Knight, Holly;
- Carlisle, Sophie;
- O'Connor, Mórna;
- Briggs, Lydia;
- Fothergill, Lauren;
- Al-Oraibi, Amani;
- Yildirim, Mehmet;
- Morling, Joanne R.;
- Corner, Jessica;
- Ball, Jonathan;
- Denning, Chris;
- Vedhara, Kavita;
- Blake, Holly
Publication type:
Article
Students' Views towards Sars-Cov-2 Mass Asymptomatic Testing, Social Distancing and Self-Isolation in a University Setting during the COVID-19 Pandemic: A Qualitative Study.
Published in:
International Journal of Environmental Research & Public Health, 2021, v. 18, n. 8, p. 4182, doi. 10.3390/ijerph18084182
By:
- Blake, Holly;
- Knight, Holly;
- Jia, Ru;
- Corner, Jessica;
- Morling, Joanne R.;
- Denning, Chris;
- Ball, Jonathan K.;
- Bolton, Kirsty;
- Figueredo, Grazziela;
- Morris, David E.;
- Tighe, Patrick;
- Villalon, Armando Mendez;
- Ayling, Kieran;
- Vedhara, Kavita
Publication type:
Article
Characterisation of the invasive tumour niche using astrocyte-glioblastoma organoids and decellularised human brain.
Published in:
Neuro-Oncology, 2019, v. 21, p. 7, doi. 10.1093/neuonc/noz167.028
By:
- Diksin, Mohammed;
- Rowlinson, Jonathan;
- Kondrashov, Alexandar;
- Denning, Chris;
- Hughes, Jamie;
- Constantin-Teodo, Tim;
- Cui, Wei;
- Gell, Chris;
- Onion, David;
- Croxall, Nicola;
- Smith, Stuart;
- Rahman, Ruman
Publication type:
Article
The use of fluorescence correlation spectroscopy to monitor cell surface β2-adrenoceptors at low expression levels in human embryonic stem cell-derived cardiomyocytes and fibroblasts.
Published in:
FASEB Journal, 2021, v. 35, n. 4, p. 1, doi. 10.1096/fj.202002268R
By:
- Goulding, Joëlle;
- Kondrashov, Alexander;
- Mistry, Sarah J.;
- Melarangi, Tony;
- Vo, Nguyen T. N.;
- Hoang, Duc M.;
- White, Carl W.;
- Denning, Chris;
- Briddon, Stephen J.;
- Hill, Stephen J.
Publication type:
Article
Derivation and characterisation of the human embryonic stem cell lines, NOTT1 and NOTT2.
Published in:
In Vitro Cellular & Developmental Biology Animal, 2010, v. 46, n. 3/4, p. 367, doi. 10.1007/s11626-010-9290-6
By:
- Priddle, Helen;
- Allegrucci, Cinzia;
- Burridge, Paul;
- Munoz, Maria;
- Smith, Nigel;
- Devlin, Lyndsey;
- Sjoblom, Cecilia;
- Chamberlain, Sarah;
- Watson, Sue;
- Young, Lorraine;
- Denning, Chris
Publication type:
Article
Direct RT-qPCR Assay for the Detection of SARS-CoV-2 in Saliva Samples.
Published in:
Methods & Protocols, 2022, v. 5, n. 2, p. N.PAG, doi. 10.3390/mps5020025
By:
- Tarantini, Francesco Saverio;
- Wu, Siyu;
- Jenkins, Harry;
- Tellechea Lopez, Ana;
- Tomlin, Hannah;
- Hyde, Ralph;
- Lis-Slimak, Katarzyna;
- Thompson, Jamie Louise;
- Pijuan-Galitó, Sara;
- Scales, Danielle;
- Kaneko, Kazuyo;
- Dey, Jayasree;
- Park, Emily;
- Hill, Jack;
- Lee, I-Ning;
- Doolan, Lara;
- Arendt-Tranholm, Asta;
- Denning, Chris;
- Seedhouse, Claire;
- Benest, Andrew V.
Publication type:
Article
Directed Differentiation of Human Embryonic Stem Cells to Interrogate the Cardiac Gene Regulatory Network.
Published in:
Molecular Therapy, 2011, v. 19, n. 9, p. 1695, doi. 10.1038/mt.2011.125
By:
- Dixon, James E.;
- Dick, Emily;
- Rajamohan, Divya;
- Shakesheff, Kevin M.;
- Denning, Chris
Publication type:
Article
Complex Relationship Between Cardiac Fibroblasts and Cardiomyocytes in Health and Disease.
Published in:
2021
By:
- Hall, Caitlin;
- Gehmlich, Katja;
- Denning, Chris;
- Pavlovic, Davor
Publication type:
journal article
Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D.
Published in:
Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00259
By:
- Zhou, Xin;
- Bueno-Orovio, Alfonso;
- Schilling, Richard J.;
- Kirkby, Claire;
- Denning, Chris;
- Rajamohan, Divya;
- Burrage, Kevin;
- Tinker, Andrew;
- Rodriguez, Blanca;
- Harmer, Stephen C.
Publication type:
Article
Transgenic Enrichment of Cardiomyocytes From Human Embryonic Stem Cells.
Published in:
Molecular Therapy, 2007, v. 15, n. 11, p. 2027, doi. 10.1038/sj.mt.6300303
By:
- Anderson, David;
- Self, Tim;
- Mellor, Ian R.;
- Goh, Gareth;
- Hill, Stephen J.;
- Denning, Chris
Publication type:
Article
Proliferative lifespan is conserved after nuclear transfer.
Published in:
Nature Cell Biology, 2003, v. 5, n. 6, p. 535, doi. 10.1038/ncb992
By:
- Clark, A. John;
- Ferrier, Patricia;
- Aslam, Samena;
- Burl, Sarah;
- Denning, Chris;
- Wylie, Diana;
- Ross, Arlene;
- de Sousa, Paul;
- Wilmut, Ian;
- Cui, Wei
Publication type:
Article
Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes.
Published in:
European Heart Journal, 2014, v. 35, n. 16, p. 1078, doi. 10.1093/eurheartj/eht067
By:
- Matsa, Elena;
- Dixon, James E.;
- Medway, Christopher;
- Georgiou, Orestis;
- Patel, Minal J.;
- Morgan, Kevin;
- Kemp, Paul J.;
- Staniforth, Andrew;
- Mellor, Ian;
- Denning, Chris
Publication type:
Article
Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation.
Published in:
European Heart Journal, 2011, v. 32, n. 8, p. 952, doi. 10.1093/eurheartj/ehr073
By:
- Matsa, Elena;
- Rajamohan, Divya;
- Dick, Emily;
- Young, Lorraine;
- Mellor, Ian;
- Staniforth, Andrew;
- Denning, Chris
Publication type:
Article
Improved Human Embryonic Stem Cell Embryoid Body Homogeneity and Cardiomyocyte Differentiation from a Novel V-96 Plate Aggregation System Highlights Interline Variability.
Published in:
Stem Cells, 2007, v. 25, n. 4, p. 929, doi. 10.1634/stemcells.2006-0598
By:
- Burridge, Paul W.;
- Anderson, David;
- Priddle, Helen;
- Muñoz, Maria D. Barbadillo;
- Chamberlain, Sarah;
- Allegrucci, Cinzia;
- Young, Lorraine E.;
- Denning, Chris
Publication type:
Article
A Qualitative Evaluation of the Barriers and Enablers for Implementation of an Asymptomatic SARS-CoV-2 Testing Service at the University of Nottingham: A Multi-Site Higher Education Setting in England.
Published in:
International Journal of Environmental Research & Public Health, 2022, v. 19, n. 20, p. 13140, doi. 10.3390/ijerph192013140
By:
- Blake, Holly;
- Somerset, Sarah;
- Mahmood, Ikra;
- Mahmood, Neelam;
- Corner, Jessica;
- Ball, Jonathan K.;
- Denning, Chris
Publication type:
Article
Workforce Experiences of a Rapidly Established SARS-CoV-2 Asymptomatic Testing Service in a Higher Education Setting: A Qualitative Study.
Published in:
International Journal of Environmental Research & Public Health, 2022, v. 19, n. 19, p. 12464, doi. 10.3390/ijerph191912464
By:
- Blake, Holly;
- Somerset, Sarah;
- Mahmood, Ikra;
- Mahmood, Neelam;
- Corner, Jessica;
- Ball, Jonathan K.;
- Denning, Chris
Publication type:
Article
Simultaneous measurement of excitation-contraction coupling parameters identifies mechanisms underlying contractile responses of hiPSC-derived cardiomyocytes.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12354-8
By:
- van Meer, Berend J.;
- Krotenberg, Ana;
- Sala, Luca;
- Davis, Richard P.;
- Eschenhagen, Thomas;
- Denning, Chris;
- Tertoolen, Leon G. J.;
- Mummery, Christine L.
Publication type:
Article
Dynamics of 5-carboxylcytosine during hepatic differentiation: Potential general role for active demethylation by DNA repair in lineage specification.
Published in:
Epigenetics, 2017, v. 12, n. 4, p. 277, doi. 10.1080/15592294.2017.1292189
By:
- Lewis, Lara C.;
- Lo, Peggy Cho Kiu;
- Foster, Jeremy M.;
- Dai, Nan;
- Corrêa, Ivan R.;
- Durczak, Paulina M.;
- Duncan, Gary;
- Ramsawhook, Ashley;
- Aithal, Guruprasad Padur;
- Denning, Chris;
- Hannan, Nicholas R. F.;
- Ruzov, Alexey
Publication type:
Article
5-hydroxymethyl-cytosine enrichment of non-committed cells is not a universal feature of vertebrate development.
Published in:
Epigenetics, 2012, v. 7, n. 4, p. 383, doi. 10.4161/epi.19375
By:
- Almeida, Rimple D.;
- Loose, Matthew;
- Sottile, Virginie;
- Matsa, Elena;
- Denning, Chris;
- Young, Lorraine;
- Johnson, Andrew D.;
- Gering, Martin;
- Ruzov, Alexey
Publication type:
Article
Materials for stem cell factories of the future.
Published in:
Nature Materials, 2014, v. 13, n. 6, p. 570, doi. 10.1038/nmat3972
By:
- Celiz, Adam D.;
- Smith, James G. W.;
- Langer, Robert;
- Anderson, Daniel G.;
- Winkler, David A.;
- Barrett, David A.;
- Davies, Martyn C.;
- Young, Lorraine E.;
- Denning, Chris;
- Alexander, Morgan R.
Publication type:
Article
Biomaterials Discovery: Discovery of a Novel Polymer for Xeno‐Free, Long‐Term Culture of Human Pluripotent Stem Cell Expansion (Adv. Healthcare Mater. 6/2021).
Published in:
Advanced Healthcare Materials, 2021, v. 10, n. 6, p. 1, doi. 10.1002/adhm.202170019
By:
- Nasir, Aishah;
- Thorpe, Jordan;
- Burroughs, Laurence;
- Meurs, Joris;
- Pijuan‐Galito, Sara;
- Irvine, Derek J.;
- Alexander, Morgan R.;
- Denning, Chris
Publication type:
Article
Discovery of a Novel Polymer for Xeno‐Free, Long‐Term Culture of Human Pluripotent Stem Cell Expansion.
Published in:
Advanced Healthcare Materials, 2021, v. 10, n. 6, p. 1, doi. 10.1002/adhm.202001448
By:
- Nasir, Aishah;
- Thorpe, Jordan;
- Burroughs, Laurence;
- Meurs, Joris;
- Pijuan‐Galito, Sara;
- Irvine, Derek J.;
- Alexander, Morgan R.;
- Denning, Chris
Publication type:
Article
Toward label-free Raman-activated cell sorting of cardiomyocytes derived from human embryonic stem cells.
Published in:
Journal of Biomedical Optics, 2011, v. 16, n. 4, p. 045002, doi. 10.1117/1.3570302
By:
- Flavius C. Pascut;
- Huey T. Goh;
- Vinoj George;
- Chris Denning;
- Ioan Notingher
Publication type:
Article
Quantifiable correlation of ToF‐SIMS and XPS data from polymer surfaces with controlled amino acid and peptide content.
Published in:
Surface & Interface Analysis: SIA, 2022, v. 54, n. 4, p. 417, doi. 10.1002/sia.7052
By:
- Taylor, Michael;
- Simoes, Fabio;
- Smith, James;
- Genapathy, Sivaneswary;
- Canning, Anne;
- Lledos, Marina;
- Chan, Weng C.;
- Denning, Chris;
- Scurr, David J.;
- Steven, Rory T.;
- Spencer, Steve J.;
- Shard, Alexander G.;
- Alexander, Morgan R.;
- Zelzer, Mischa
Publication type:
Article