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Sexual Fate Change of XX Germ Cells Caused by the Deletion of SMAD4 and STRA8 Independent of Somatic Sex Reprogramming.
- Published in:
- PLoS Biology, 2016, v. 14, n. 9, p. 1, doi. 10.1371/journal.pbio.1002553
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- Publication type:
- Article
Fueling sentinel node via reshaping cytotoxic T lymphocytes with a flex-patch for post-operative immuno-adjuvant therapy.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38245-7
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- Publication type:
- Article
ATM–Chk2–p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
- Published in:
- EMBO Journal, 2006, v. 25, n. 10, p. 2167, doi. 10.1038/sj.emboj.7601115
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- Publication type:
- Article
SRC-3, a Steroid Receptor Coactivator: Implication in Cancer.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4760, doi. 10.3390/ijms22094760
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- Publication type:
- Article
Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.
- Published in:
- 2011
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- Publication type:
- journal article
A selective EP4 PGE2 receptor agonist alleviates disease in a new mouse model of X-linked nephrogenic diabetes insipidus.
- Published in:
- 2009
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- Publication type:
- journal article
Maternal disturbance in activated sphingolipid metabolism causes pregnancy loss in mice.
- Published in:
- 2007
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- Publication type:
- journal article
Mouse models of BRCA1 and their application to breast cancer research.
- Published in:
- Cancer & Metastasis Reviews, 2013, v. 32, n. 1/2, p. 25, doi. 10.1007/s10555-012-9403-7
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- Publication type:
- Article
FGFR2–BRD4 Axis Regulates Transcriptional Networks of Histone 3 Modification and Synergy Between Its Inhibitors and PD-1/PD-L1 in a TNBC Mouse Model.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.861221
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- Publication type:
- Article
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun.
- Published in:
- Nature Medicine, 2012, v. 18, n. 11, p. 1643, doi. 10.1038/nm.2961
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- Publication type:
- Article
Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155.
- Published in:
- 2011
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- Publication type:
- Correction Notice
Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155.
- Published in:
- Nature Medicine, 2011, v. 17, n. 10, p. 1275, doi. 10.1038/nm.2459
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- Publication type:
- Article
Silencing of unsynapsed meiotic chromosomes in the mouse.
- Published in:
- Nature Genetics, 2005, v. 37, n. 1, p. 41, doi. 10.1038/ng1484
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- Publication type:
- Article
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.
- Published in:
- Nature Genetics, 2001, v. 28, n. 3, p. 266, doi. 10.1038/90108
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- Publication type:
- Article
Genomic instability in Gadd45a-deficient mice.
- Published in:
- Nature Genetics, 1999, v. 23, n. 2, p. 176, doi. 10.1038/13802
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- Publication type:
- Article
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
- Published in:
- Nature Genetics, 1999, v. 22, n. 1, p. 37, doi. 10.1038/8743
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- Publication type:
- Article
Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes.
- Published in:
- Journal of Cellular Physiology, 2021, v. 236, n. 2, p. 981, doi. 10.1002/jcp.29909
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- Publication type:
- Article
Generation of Smad4/Dpc4 conditional knockout mice.
- Published in:
- Genesis: The Journal of Genetics & Development, 2002, v. 32, n. 2, p. 80, doi. 10.1002/gene.10029
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- Publication type:
- Article
Generation of Fgfr1 conditional knockout mice.
- Published in:
- Genesis: The Journal of Genetics & Development, 2002, v. 32, n. 2, p. 85, doi. 10.1002/gene.10028
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- Publication type:
- Article
Direct removal in the mouse of a floxed neo gene from a three-loxp conditional knockout allele by two novel approaches.
- Published in:
- Genesis: The Journal of Genetics & Development, 2001, v. 30, n. 1, p. 1, doi. 10.1002/gene.1025
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- Publication type:
- Article
Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning.
- Published in:
- Developmental Dynamics, 2001, v. 222, n. 3, p. 471, doi. 10.1002/dvdy.1205
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- Publication type:
- Article
Drug screening of cancer cell lines and human primary tumors using droplet microfluidics.
- Published in:
- Scientific Reports, 2017, v. 7, n. 1, p. 1, doi. 10.1038/s41598-017-08831-z
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- Publication type:
- Article
WEE1 inhibition targets cell cycle checkpoints for triple negative breast cancers to overcome cisplatin resistance.
- Published in:
- Scientific Reports, 2017, p. 43517, doi. 10.1038/srep43517
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- Publication type:
- Article
Smad4 is required to inhibit osteoclastogenesis and maintain bone mass.
- Published in:
- Scientific Reports, 2016, p. 35221, doi. 10.1038/srep35221
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- Publication type:
- Article
Negative reciprocal regulation between Sirt1 and Per2 modulates the circadian clock and aging.
- Published in:
- Scientific Reports, 2016, p. 28633, doi. 10.1038/srep28633
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- Publication type:
- Article
Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway.
- Published in:
- Scientific Reports, 2015, p. 16974, doi. 10.1038/srep16974
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- Publication type:
- Article
Standard: Human intestinal organoids.
- Published in:
- 2023
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- Publication type:
- Editorial
Standard: Human intestinal cancer organoids.
- Published in:
- 2023
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- Publication type:
- Editorial
Sirt6 ablation in the liver causes fatty liver that increases cancer risky by upregulating Serpina12.
- Published in:
- EMBO Reports, 2024, v. 25, n. 3, p. 1361, doi. 10.1038/s44319-024-00071-3
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- Publication type:
- Article
Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer.
- Published in:
- Oncogene, 2005, v. 24, n. 22, p. 3554, doi. 10.1038/sj.onc.1208426
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- Publication type:
- Article
Tumor formation in mice with conditional inactivation of Brca1 in epithelial tissues.
- Published in:
- Oncogene, 2003, v. 22, n. 35, p. 5415, doi. 10.1038/sj.onc.1206825
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- Publication type:
- Article
BRCA1 shifts p53-mediated cellular outcomes towards irreversible growth arrest.
- Published in:
- Oncogene, 2003, v. 22, n. 24, p. 3749, doi. 10.1038/sj.onc.1206439
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- Publication type:
- Article
Normal lymphocyte development and thymic lymphoma formation in Brca1 exon-11-deficient mice.
- Published in:
- Oncogene, 2003, v. 22, n. 4, p. 528, doi. 10.1038/sj.onc.1206208
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- Publication type:
- Article
Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice.
- Published in:
- Oncogene, 2001, v. 20, n. 51, p. 7514, doi. 10.1038/sj.onc.1204929
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- Publication type:
- Article
Ablation of Smurf2 reveals an inhibition in TGF-? signalling through multiple mono-ubiquitination of Smad3.
- Published in:
- EMBO Journal, 2011, v. 30, n. 23, p. 4777, doi. 10.1038/emboj.2011.393
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- Publication type:
- Article
Human Follicle-Stimulating Hormone ß Subunit Expression Depends on FOXL2 and SMAD4.
- Published in:
- Endocrinology, 2020, v. 161, n. 5, p. 1, doi. 10.1210/endocr/bqaa045
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- Publication type:
- Article
Bmi1 regulates mitochondrial function and the DNA damage response pathway.
- Published in:
- Nature, 2009, v. 459, n. 7245, p. 387, doi. 10.1038/nature08040
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- Publication type:
- Article
Expansion of Rare Cancer Cells into Tumoroids for Therapeutic Regimen and Cancer Therapy.
- Published in:
- Advanced Therapeutics, 2021, v. 4, n. 7, p. 1, doi. 10.1002/adtp.202100017
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- Publication type:
- Article
Mesenchymal Stromal Cells Increase the Natural Killer Resistance of Circulating Tumor Cells via Intercellular Signaling of cGAS‐STING‐IFNβ‐HLA.
- Published in:
- Advanced Science, 2024, v. 11, n. 21, p. 1, doi. 10.1002/advs.202400888
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- Publication type:
- Article
Photocatalytic Pt(IV)‐Coordinated Carbon Dots for Precision Tumor Therapy.
- Published in:
- Advanced Science, 2022, v. 9, n. 36, p. 1, doi. 10.1002/advs.202205106
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- Publication type:
- Article
Toward Strong Near‐Infrared Absorption/Emission from Carbon Dots in Aqueous Media through Solvothermal Fusion of Large Conjugated Perylene Derivatives with Post‐Surface Engineering.
- Published in:
- Advanced Science, 2022, v. 9, n. 23, p. 1, doi. 10.1002/advs.202202283
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- Publication type:
- Article
Oxygen‐Enriched Metal‐Phenolic X‐Ray Nanoprocessor for Cancer Radio‐Radiodynamic Therapy in Combination with Checkpoint Blockade Immunotherapy.
- Published in:
- Advanced Science, 2021, v. 8, n. 4, p. 1, doi. 10.1002/advs.202003338
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- Publication type:
- Article
BRCA1 Deficiency: BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis (Adv. Sci. 6/2020).
- Published in:
- Advanced Science, 2020, v. 7, n. 6, p. 1, doi. 10.1002/advs.202070033
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- Publication type:
- Article
BRCA1 Deficiency Impairs Mitophagy and Promotes Inflammasome Activation and Mammary Tumor Metastasis.
- Published in:
- Advanced Science, 2020, v. 7, n. 6, p. 1, doi. 10.1002/advs.201903616
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- Publication type:
- Article
Inactivation of p53 tumor suppressor gene acts synergistically with c-neu oncogene in salivary gland tumorigenesis.
- Published in:
- Oncogene, 2001, v. 20, n. 12, p. 1445, doi. 10.1038/sj.onc.1204222
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- Publication type:
- Article
Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice.
- Published in:
- Oncogene, 2000, v. 19, n. 15, p. 1868, doi. 10.1038/sj.onc.1203504
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- Publication type:
- Article
Role of the tumor suppressor gene Brca1 in genetic stability and mammary gland tumor formation.
- Published in:
- Oncogene, 2000, v. 19, n. 8, p. 1059, doi. 10.1038/sj.onc.1203269
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- Publication type:
- Article
A targeted disruption of the murine Brca1 gene causes γ-irradiation hypersensitivity and genetic instability.
- Published in:
- Oncogene, 1998, v. 17, n. 24, p. 3115, doi. 10.1038/sj.onc.1202243
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- Publication type:
- Article
BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution.
- Published in:
- Nucleic Acids Research, 2006, v. 34, n. 5, p. 1416, doi. 10.1093/nar/gkl010
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- Publication type:
- Article
Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.
- Published in:
- Nucleic Acids Research, 2005, v. 33, n. 11, p. e102, doi. 10.1093/nar/gni100
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- Publication type:
- Article