Works matching AU Delgoffe, Greg M.

Results: 24

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

Published in:

Nature Immunology, 2011, v. 12, n. 4, p. 295, doi. 10.1038/ni.2005

By:

Delgoffe, Greg M;
Pollizzi, Kristen N;
Waickman, Adam T;
Heikamp, Emily;
Meyers, David J;
Horton, Maureen R;
Xiao, Bo;
Worley, Paul F;
Powell, Jonathan D

Publication type:

Article

Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted.

Published in:

2018

By:

Tilstra, Jeremy S.;
Avery, Lyndsay;
Menk, Ashley V.;
Gordon, Rachael A.;
Smita, Shuchi;
Kane, Lawrence P.;
Chikina, Maria;
Delgoffe, Greg M.;
Shlomchik, Mark J.

Publication type:

journal article

ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation.

Published in:

2018

By:

Vendetti, Frank P.;
Karukonda, Pooja;
Clump, David A.;
Teo, Troy;
Lalonde, Ronald;
Nugent, Katriana;
Ballew, Matthew;
Kiesel, Brian F.;
Beumer, Jan H.;
Sarkar, Saumendra N.;
Conrads, Thomas P.;
O'Connor, Mark J.;
Ferris, Robert L.;
Tran, Phuoc T.;
Delgoffe, Greg M.;
Bakkenist, Christopher J.

Publication type:

journal article

mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.

Published in:

2015

By:

Pollizzi, Kristen N;
Patel, Chirag H;
Sun, Im-Hong;
Oh, Min-Hee;
Waickman, Adam T;
Wen, Jiayu;
Delgoffe, Greg M;
Powell, Jonathan D

Publication type:

journal article

mTORC1 and mTORC2 selectively regulate CD8+ T cell differentiation.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 5, p. 2090, doi. 10.1172/JCI77746

By:

Pollizzi, Kristen N.;
Patel, Chirag H.;
Im-Hong Sun;
Min-Hee Oh;
Waickman, Adam T.;
Jiayu Wen;
Delgoffe, Greg M.;
Powell, Jonathan D.

Publication type:

Article

Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology.

Published in:

OncoImmunology, 2022, v. 11, n. 1, p. 1, doi. 10.1080/2162402X.2022.2131229

By:

Lontos, Konstantinos;
Yiyang Wang;
Colbert, Mason;
Kumar, Alok;
Joshi, Supriya;
Philbin, Mary;
Yupeng Wang;
Frisch, Andrew;
Lohmueller, Jason;
Rivadeneira, Dayana B.;
Delgoffe, Greg M.

Publication type:

Article

Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment.

Published in:

OncoImmunology, 2020, v. 9, n. 1, p. 1, doi. 10.1080/2162402X.2019.1708064

By:

Yang, Min;
Du, Wenwen;
Yi, Lixian;
Wu, Shaoxian;
He, Chunyan;
Zhai, Wensi;
Yue, Cuihua;
Sun, Runzi;
Menk, Ashley V.;
Delgoffe, Greg M.;
Jiang, Jingting;
Lu, Binfeng

Publication type:

Article

Evaluation of radiomics as a predictor of efficacy and the tumor immune microenvironment in anti‐PD‐1 mAb treated recurrent/metastatic squamous cell carcinoma of the head and neck patients.

Published in:

Head & Neck, 2025, v. 47, n. 1, p. 129, doi. 10.1002/hed.27878

By:

Zandberg, Dan P.;
Zenkin, Serafettin;
Ak, Murat;
Mamindla, Priyadarshini;
Peddagangireddy, Vishal;
Hsieh, Ronan;
Anderson, Jennifer L.;
Delgoffe, Greg M.;
Menk, Ashely;
Skinner, Heath D.;
Duvvuri, Umamaheswar;
Ferris, Robert L.;
Colen, Rivka R.

Publication type:

Article

89723 CD105-targeted CAR T cells for the treatment of acute myeloid leukemia.

Published in:

2021

By:

Lontos, Konstantinos;
Wang, Yiyang;
Frisch, Andrew;
Colbert, Mason;
Lohmueller, Jason;
Delgoffe, Greg M.

Publication type:

Abstract

Characteristics of the Tumor Microenvironment That Influence Immune Cell Functions: Hypoxia, Oxidative Stress, Metabolic Alterations.

Published in:

Cancers, 2020, v. 12, n. 12, p. 3802, doi. 10.3390/cancers12123802

By:

Augustin, Ryan C.;
Delgoffe, Greg M.;
Najjar, Yana G.

Publication type:

Article

Burnout in science.

Published in:

Immunology, 2023, v. 169, n. 1, p. 1, doi. 10.1111/imm.13639

By:

Delgoffe, Greg M.

Publication type:

Article

Niche topics and location, location, location, with Amanda Lund.

Published in:

Immunology, 2022, v. 166, n. 2, p. 153, doi. 10.1111/imm.13492

By:

Lund, Amanda W.;
Delgoffe, Greg M.

Publication type:

Article

Editorial: Perspectives on the landscape of immunology from Nikhil Joshi.

Published in:

Immunology, 2022, v. 165, n. 4, p. 369, doi. 10.1111/imm.13467

By:

Joshi, Nikhil S.;
Delgoffe, Greg M.

Publication type:

Article

The composition and signaling of the IL-35 receptor are unconventional.

Published in:

Nature Immunology, 2012, v. 13, n. 3, p. 290, doi. 10.1038/ni.2227

By:

Collison, Lauren W;
Delgoffe, Greg M;
Guy, Clifford S;
Vignali, Kate M;
Chaturvedi, Vandana;
Fairweather, DeLisa;
Satoskar, Abhay R;
Garcia, K Christopher;
Hunter, Christopher A;
Drake, Charles G;
Murray, Peter J;
Vignali, Dario A A

Publication type:

Article

Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells.

Published in:

Nature Communications, 2017, v. 8, n. 3, p. 14649, doi. 10.1038/ncomms14649

By:

Downs-Canner, Stephanie;
Berkey, Sara;
Delgoffe, Greg M.;
Edwards, Robert P.;
Curiel, Tyler;
Odunsi, Kunle;
Bartlett, David L.;
Obermajer, Nataša

Publication type:

Article

mTOR: taking cues from the immune microenvironment.

Published in:

Immunology, 2009, v. 127, n. 4, p. 459, doi. 10.1111/j.1365-2567.2009.03125.x

By:

Delgoffe, Greg M.;
Powell, Jonathan D.

Publication type:

Article

A Fox of a different color: FoxA1 programs a new regulatory T cell subset.

Published in:

Nature Medicine, 2014, v. 20, n. 3, p. 236, doi. 10.1038/nm.3493

By:

Delgoffe, Greg M.;
Vignali, Dario A. A.

Publication type:

Article

Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection.

Published in:

PLoS Pathogens, 2023, v. 19, n. 11, p. 1, doi. 10.1371/journal.ppat.1011719

By:

Carreno-Florez, Grace P.;
Kocak, Brian R.;
Hendricks, Matthew R.;
Melvin, Jeffrey A.;
Mar, Katrina B.;
Kosanovich, Jessica;
Cumberland, Rachel L.;
Delgoffe, Greg M.;
Shiva, Sruti;
Empey, Kerry M.;
Schoggins, John W.;
Bomberger, Jennifer M.

Publication type:

Article

Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells.

Published in:

Science Immunology, 2022, v. 7, n. 74, p. 1, doi. 10.1126/sciimmunol.abj9123

By:

Ford, B. Rhodes;
Vignali, Paolo D. A.;
Rittenhouse, Natalie L.;
Scharping, Nicole E.;
Peralta, Ronal;
Lontos, Konstantinos;
Frisch, Andrew T.;
Delgoffe, Greg M.;
Poholek, Amanda C.

Publication type:

Article

Tumor and T-Cell Metabolism: New Insights Into Melanoma Therapy.

Published in:

Clinical Advances in Hematology & Oncology, 2016, v. 14, n. 4, p. 232

By:

Delgoffe, Greg M.

Publication type:

Article

Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.

Published in:

Nature, 2013, v. 501, n. 7466, p. 252, doi. 10.1038/nature12428

By:

Delgoffe, Greg M.;
Woo, Seng-Ryong;
Turnis, Meghan E.;
Gravano, David M.;
Guy, Cliff;
Overacre, Abigail E.;
Bettini, Matthew L.;
Vogel, Peter;
Finkelstein, David;
Bonnevier, Jody;
Workman, Creg J.;
Vignali, Dario A. A.

Publication type:

Article

mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01451

By:

Watson, Alicia R.;
Dai, Helong;
Zheng, Yawen;
Nakano, Ryosuke;
Giannou, Anastasios D.;
Menk, Ashley V.;
Stolz, Donna B.;
Delgoffe, Greg M.;
Thomson, Angus W.

Publication type:

Article

Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease.

Published in:

Science Translational Medicine, 2020, v. 12, n. 548, p. 1, doi. 10.1126/scitranslmed.aay5691

By:

Jawale, Chetan V.;
Ramani, Kritika;
Li, De-dong;
Coleman, Bianca M.;
Oberoi, Rohan S.;
Kupul, Saran;
Lin, Li;
Desai, Jigar V.;
Delgoffe, Greg M.;
Lionakis, Michail S.;
Bender, Filitsa H.;
Prokopienko, Alexander J.;
Nolin, Thomas D.;
Gaffen, Sarah L.;
Biswas, Partha S.

Publication type:

Article

Metformin is associated with improved clinical outcomes in patients with melanoma: a retrospective, multi-institutional study.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1075823

By:

Augustin, Ryan C.;
Ziyu Huang;
Fei Ding;
Shuyan Zhai;
McArdle, Jennifer;
Santisi, Anthony;
Davis, Michael;
Sander, Cindy;
Davar, Diwakar;
Kirkwood, John M.;
Delgoffe, Greg M.;
Warner, Allison Betof;
Najjar, Yana G.

Publication type:

Article

Works matching AU Delgoffe, Greg M.

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.

Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted.

ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation.

mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.

mTORC1 and mTORC2 selectively regulate CD8<sup>+</sup> T cell differentiation.

Fully murine CD105-targeted CAR-T cells provide an immunocompetent model for CAR-T cell biology.

Checkpoint molecules coordinately restrain hyperactivated effector T cells in the tumor microenvironment.

Evaluation of radiomics as a predictor of efficacy and the tumor immune microenvironment in anti‐PD‐1 mAb treated recurrent/metastatic squamous cell carcinoma of the head and neck patients.

89723 CD105-targeted CAR T cells for the treatment of acute myeloid leukemia.

Characteristics of the Tumor Microenvironment That Influence Immune Cell Functions: Hypoxia, Oxidative Stress, Metabolic Alterations.

Burnout in science.

Niche topics and location, location, location, with Amanda Lund.

Editorial: Perspectives on the landscape of immunology from Nikhil Joshi.

The composition and signaling of the IL-35 receptor are unconventional.

Suppressive IL-17A<sup>+</sup>Foxp3<sup>+</sup> and ex-Th17 IL-17A<sup>neg</sup>Foxp3<sup>+</sup> T<sub>reg</sub> cells are a source of tumour-associated T<sub>reg</sub> cells.

mTOR: taking cues from the immune microenvironment.

A Fox of a different color: FoxA1 programs a new regulatory T cell subset.

Interferon signaling drives epithelial metabolic reprogramming to promote secondary bacterial infection.

Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells.

Tumor and T-Cell Metabolism: New Insights Into Melanoma Therapy.

Stability and function of regulatory T cells is maintained by a neuropilin-1-semaphorin-4a axis.

mTORC2 Deficiency Alters the Metabolic Profile of Conventional Dendritic Cells.

Restoring glucose uptake rescues neutrophil dysfunction and protects against systemic fungal infection in mouse models of kidney disease.

Metformin is associated with improved clinical outcomes in patients with melanoma: a retrospective, multi-institutional study.