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A novel approach to inhibit bone resorption: exosite inhibitors against cathepsin K.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Degradation of collagen in the bone-resorbing compartment underlying the osteoclast involves both cysteine-proteinases and matrix metalloproteinases.
- Published in:
- Journal of Cellular Physiology, 1992, v. 150, n. 2, p. 221, doi. 10.1002/jcp.1041500202
- By:
- Publication type:
- Article
Osteoclast Fusion is Based on Heterogeneity Between Fusion Partners.
- Published in:
- Calcified Tissue International, 2014, v. 95, n. 1, p. 73, doi. 10.1007/s00223-014-9864-5
- By:
- Publication type:
- Article
The Bone Resorption Inhibitors Odanacatib and Alendronate Affect Post-Osteoclastic Events Differently in Ovariectomized Rabbits.
- Published in:
- Calcified Tissue International, 2014, v. 94, n. 2, p. 212, doi. 10.1007/s00223-013-9800-0
- By:
- Publication type:
- Article
Glucocorticoid-Induced Changes in the Geometry of Osteoclast Resorption Cavities Affect Trabecular Bone Stiffness.
- Published in:
- Calcified Tissue International, 2013, v. 92, n. 3, p. 240, doi. 10.1007/s00223-012-9674-6
- By:
- Publication type:
- Article
Potential of resveratrol analogues as antagonists of osteoclasts and promoters of osteoblasts.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Fusion Potential of Human Osteoclasts In Vitro Reflects Age, Menopause, and In Vivo Bone Resorption Levels of Their Donors—A Possible Involvement of DC-STAMP.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 17, p. 6368, doi. 10.3390/ijms21176368
- By:
- Publication type:
- Article
Osteoclasts' Ability to Generate Trenches Rather Than Pits Depends on High Levels of Active Cathepsin K and Efficient Clearance of Resorption Products.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5924, doi. 10.3390/ijms21165924
- By:
- Publication type:
- Article
OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice.
- Published in:
- 2011
- By:
- Publication type:
- journal article
Is retention of zoledronic acid onto bone different in multiple myeloma and breast cancer patients with bone metastasis?
- Published in:
- Journal of Bone & Mineral Research, 2013, v. 28, n. 8, p. 1738, doi. 10.1002/jbmr.1897
- By:
- Publication type:
- Article
Increased presence of capillaries next to remodeling sites in adult human cancellous bone.
- Published in:
- Journal of Bone & Mineral Research, 2013, v. 28, n. 3, p. 574, doi. 10.1002/jbmr.1760
- By:
- Publication type:
- Article
Premature loss of bone remodeling compartment canopies is associated with deficient bone formation: A study of healthy individuals and patients with cushing's syndrome.
- Published in:
- Journal of Bone & Mineral Research, 2012, v. 27, n. 4, p. 770, doi. 10.1002/jbmr.1490
- By:
- Publication type:
- Article
Estrogen inhibits Dlk1/FA1 production: A potential mechanism for estrogen effects on bone turnover.
- Published in:
- Journal of Bone & Mineral Research, 2011, v. 26, n. 10, p. 2548, doi. 10.1002/jbmr.444
- By:
- Publication type:
- Article
Glucocorticoids Maintain Human Osteoclasts in the Active Mode of Their Resorption Cycle.
- Published in:
- Journal of Bone & Mineral Research, 2010, v. 25, n. 10, p. 2184, doi. 10.1002/jbmr.113
- By:
- Publication type:
- Article
The Chloride Channel Inhibitor NS3736 Prevents Bone Resorption in Ovariectomized Rats Without Changing Bone Formation.
- Published in:
- Journal of Bone & Mineral Research, 2004, v. 19, n. 7, p. 1144, doi. 10.1359/JBMR.040302
- By:
- Publication type:
- Article
Cysteine Proteinases and Matrix Metalloproteinases Play Distinct Roles in the Subosteoclastic Resorption Zone.
- Published in:
- Journal of Bone & Mineral Research, 1998, v. 13, n. 9, p. 1420, doi. 10.1359/jbmr.1998.13.9.1420
- By:
- Publication type:
- Article
The Migration of Purified Osteoclasts Through Collagen Is Inhibited by Matrix Metalloproteinase Inhibitors.
- Published in:
- Journal of Bone & Mineral Research, 1998, v. 13, n. 1, p. 59, doi. 10.1359/jbmr.1998.13.1.59
- By:
- Publication type:
- Article
Quantification of the collagenolytic activity of isolated osteoclasts by enzyme-linked immunosorbent assay.
- Published in:
- Journal of Bone & Mineral Research, 1996, v. 11, n. 2, p. 226, doi. 10.1002/jbmr.5650110212
- By:
- Publication type:
- Article
Relationship of the plasminogen activator/plasmin cascade to osteoclast invasion and mineral resorption in explanted fetal metatarsal bones.
- Published in:
- Journal of Bone & Mineral Research, 1994, v. 9, n. 6, p. 891, doi. 10.1002/jbmr.5650090615
- By:
- Publication type:
- Article
Tissue and urokinase plasminogen activators in bone tissue and their regulation by parathyroid hormone.
- Published in:
- Journal of Bone & Mineral Research, 1991, v. 6, n. 10, p. 1081, doi. 10.1002/jbmr.5650061009
- By:
- Publication type:
- Article
High-dose therapy improves the bone remodelling compartment canopy coverage and bone formation in multiple myeloma.
- Published in:
- British Journal of Haematology, 2015, v. 171, n. 3, p. 355, doi. 10.1111/bjh.13584
- By:
- Publication type:
- Article
Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect.
- Published in:
- Bone Research, 2024, v. 12, n. 1, p. 1, doi. 10.1038/s41413-024-00362-4
- By:
- Publication type:
- Article
Aging and menopause reprogram osteoclast precursors for aggressive bone resorption.
- Published in:
- Bone Research, 2020, v. 8, n. 1, p. 1, doi. 10.1038/s41413-020-0102-7
- By:
- Publication type:
- Article
A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome.
- Published in:
- Clinical Epigenetics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13148-023-01449-1
- By:
- Publication type:
- Article
Disturbed bone marrow adiposity in patients with Cushing's syndrome and glucocorticoid-and postmenopausal-induced osteoporosis.
- Published in:
- Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1232574
- By:
- Publication type:
- Article
Human hematopoietic microenvironments.
- Published in:
- PLoS ONE, 2021, v. 16, n. 4, p. 1, doi. 10.1371/journal.pone.0250081
- By:
- Publication type:
- Article
Nonselective matrix metalloproteinase but not tumor necrosis factor-α inhibition effectively preserves the early critical colon anastomotic integrity.
- Published in:
- International Journal of Colorectal Disease, 2011, v. 26, n. 3, p. 329, doi. 10.1007/s00384-010-1106-3
- By:
- Publication type:
- Article
Multiple myeloma: changes in serum C-terminal telopeptide of collagen type I and bone-specific alkaline phosphatase can be used in daily practice to detect imminent osteolysis*.
- Published in:
- European Journal of Haematology, 2010, v. 84, n. 5, p. 412, doi. 10.1111/j.1600-0609.2010.01417.x
- By:
- Publication type:
- Article
Phosphinic Peptide Matrix Metalloproteinase-9 Inhibitors by Solid-Phase Synthesis Using a Building Block Approach.
- Published in:
- Chemistry - A European Journal, 1999, v. 5, n. 10, p. 2877, doi. 10.1002/(SICI)1521-3765(19991001)5:10<2877::AID-CHEM2877>3.0.CO;2-Z
- By:
- Publication type:
- Article
Osteoclast Fusion: Time-Lapse Reveals Involvement of CD47 and Syncytin-1 at Different Stages of Nuclearity.
- Published in:
- Journal of Cellular Physiology, 2017, v. 232, n. 6, p. 1396, doi. 10.1002/jcp.25633
- By:
- Publication type:
- Article
Early reversal cells in adult human bone remodeling: osteoblastic nature, catabolic functions and interactions with osteoclasts.
- Published in:
- Histochemistry & Cell Biology, 2016, v. 145, n. 6, p. 603, doi. 10.1007/s00418-016-1414-y
- By:
- Publication type:
- Article
Effect of withdrawal of zoledronic acid treatment on bone remodelling markers in multiple myeloma.
- Published in:
- 2010
- By:
- Publication type:
- Letter
Myeloma cell-induced disruption of bone remodelling compartments leads to osteolytic lesions and generation of osteoclast-myeloma hybrid cells.
- Published in:
- British Journal of Haematology, 2010, v. 148, n. 4, p. 551, doi. 10.1111/j.1365-2141.2009.07980.x
- By:
- Publication type:
- Article
Coordination of Fusion and Trafficking of Pre-osteoclasts at the Marrow-Bone Interface.
- Published in:
- 2019
- By:
- Publication type:
- journal article
A Mild Inhibition of Cathepsin K Paradoxically Stimulates the Resorptive Activity of Osteoclasts in Culture.
- Published in:
- 2019
- By:
- Publication type:
- journal article
Innervation is higher above Bone Remodeling Surfaces and in Cortical Pores in Human Bone: Lessons from patients with primary hyperparathyroidism.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41779-w
- By:
- Publication type:
- Article
Septins are critical regulators of osteoclastic bone resorption.
- Published in:
- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31159-1
- By:
- Publication type:
- Article
Interplay Between Immune and Cancer-Associated Fibroblasts: A Path to Target Metalloproteinases in Penile Cancer.
- Published in:
- Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.935093
- By:
- Publication type:
- Article
An assessment of ADAMs in bone cells: absence of TACE activity prevents osteoclast recruitment and the formation of the marrow cavity in developing long bones
- Published in:
- FEBS Letters, 2003, v. 553, n. 3, p. 257, doi. 10.1016/S0014-5793(03)01022-6
- By:
- Publication type:
- Article
A Critical Role of the Bone Marrow Envelope in Human Bone Remodeling.
- Published in:
- Journal of Bone & Mineral Research, 2023, v. 38, n. 6, p. 918, doi. 10.1002/jbmr.4815
- By:
- Publication type:
- Article
An Ectosteric Inhibitor of Cathepsin K Inhibits Bone Resorption in Ovariectomized Mice.
- Published in:
- 2019
- By:
- Publication type:
- Correction Notice
Intracortical Bone Mechanics Are Related to Pore Morphology and Remodeling in Human Bone.
- Published in:
- Journal of Bone & Mineral Research, 2018, v. 33, n. 12, p. 2177, doi. 10.1002/jbmr.3561
- By:
- Publication type:
- Article
Understanding Age‐Induced Cortical Porosity in Women: The Accumulation and Coalescence of Eroded Cavities Upon Existing Intracortical Canals Is the Main Contributor.
- Published in:
- Journal of Bone & Mineral Research, 2018, v. 33, n. 4, p. 606, doi. 10.1002/jbmr.3354
- By:
- Publication type:
- Article
An Ectosteric Inhibitor of Cathepsin K Inhibits Bone Resorption in Ovariectomized Mice.
- Published in:
- Journal of Bone & Mineral Research, 2017, v. 32, n. 12, p. 2415, doi. 10.1002/jbmr.3227
- By:
- Publication type:
- Article
Coupling of Bone Resorption and Formation in Real Time: New Knowledge Gained From Human Haversian BMUs.
- Published in:
- 2017
- By:
- Publication type:
- Other
CRMP4 Inhibits Bone Formation by Negatively Regulating BMP and RhoA Signaling.
- Published in:
- Journal of Bone & Mineral Research, 2017, v. 32, n. 5, p. 913, doi. 10.1002/jbmr.3069
- By:
- Publication type:
- Article
Transitory Activation and Improved Transition from Erosion to Formation within Intracortical Bone Remodeling in Hypoparathyroid Patients Treated with rhPTH(1–84).
- Published in:
- JBMR Plus, 2023, v. 7, n. 12, p. 1, doi. 10.1002/jbm4.10829
- By:
- Publication type:
- Article
Zoledronic Acid Is Not Equally Potent on Osteoclasts Generated From Different Individuals.
- Published in:
- JBMR Plus, 2020, v. 4, n. 11, p. 1, doi. 10.1002/jbm4.10412
- By:
- Publication type:
- Article
Real-time analysis of osteoclast resorption and fusion dynamics in response to bone resorption inhibitors.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-57526-9
- By:
- Publication type:
- Article