Found: 19

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  • Distinct localization of the complement C5b-9 complex on Gram-positive bacteria.

    Published in:
    Cellular Microbiology, 2013, v. 15, n. 12, p. 1955, doi. 10.1111/cmi.12170
    By:
    • Berends, Evelien T. M.;
    • Dekkers, Johanna F.;
    • Nijland, Reindert;
    • Kuipers, Annemarie;
    • Soppe, Jasper A.;
    • Strijp, Jos A. G.;
    • Rooijakkers, Suzan H. M.
    Publication type:
    Article

  • A multispectral 3D live organoid imaging platform to screen probes for fluorescence guided surgery.

    Published in:
    EMBO Molecular Medicine, 2024, v. 16, n. 7, p. 1495, doi. 10.1038/s44321-024-00084-4
    By:
    • Jeremiasse, Bernadette;
    • van Ineveld, Ravian L;
    • Bok, Veerle;
    • Kleinnijenhuis, Michiel;
    • de Blank, Sam;
    • Alieva, Maria;
    • Johnson, Hannah R;
    • van Vliet, Esmée J;
    • Zeeman, Amber L;
    • Wellens, Lianne M;
    • Llibre-Palomar, Gerard;
    • Barrera Román, Mario;
    • Di Maggio, Alessia;
    • Dekkers, Johanna F;
    • Oliveira, Sabrina;
    • Vahrmeijer, Alexander L;
    • Molenaar, Jan J;
    • Wijnen, Marc HWA;
    • van der Steeg, Alida FW;
    • Wehrens, Ellen J
    Publication type:
    Article

  • Uncovering the mode of action of engineered T cells in patient cancer organoids.

    Published in:
    Nature Biotechnology, 2023, v. 41, n. 1, p. 60, doi. 10.1038/s41587-022-01397-w
    By:
    • Dekkers, Johanna F.;
    • Alieva, Maria;
    • Cleven, Astrid;
    • Keramati, Farid;
    • Wezenaar, Amber K. L.;
    • van Vliet, Esmée J.;
    • Puschhof, Jens;
    • Brazda, Peter;
    • Johanna, Inez;
    • Meringa, Angelo D.;
    • Rebel, Heggert G.;
    • Buchholz, Maj-Britt;
    • Barrera Román, Mario;
    • Zeeman, Amber L.;
    • de Blank, Sam;
    • Fasci, Domenico;
    • Geurts, Maarten H.;
    • Cornel, Annelisa M.;
    • Driehuis, Else;
    • Millen, Rosemary
    Publication type:
    Article

  • Revealing the spatio-phenotypic patterning of cells in healthy and tumor tissues with mLSR-3D and STAPL-3D.

    Published in:
    Nature Biotechnology, 2021, v. 39, n. 10, p. 1239, doi. 10.1038/s41587-021-00926-3
    By:
    • van Ineveld, Ravian L.;
    • Kleinnijenhuis, Michiel;
    • Alieva, Maria;
    • de Blank, Sam;
    • Barrera Roman, Mario;
    • van Vliet, Esmée J.;
    • Martínez Mir, Clara;
    • Johnson, Hannah R.;
    • Bos, Frank L.;
    • Heukers, Raimond;
    • Chuva de Sousa Lopes, Susana M.;
    • Drost, Jarno;
    • Dekkers, Johanna F.;
    • Wehrens, Ellen J.;
    • Rios, Anne C.
    Publication type:
    Article

  • A functional CFTR assay using primary cystic fibrosis intestinal organoids.

    Published in:
    Nature Medicine, 2013, v. 19, n. 7, p. 939, doi. 10.1038/nm.3201
    By:
    • Dekkers, Johanna F;
    • Wiegerinck, Caroline L;
    • de Jonge, Hugo R;
    • Bronsveld, Inez;
    • Janssens, Hettie M;
    • de Winter-de Groot, Karin M;
    • Brandsma, Arianne M;
    • de Jong, Nienke W M;
    • Bijvelds, Marcel J C;
    • Scholte, Bob J;
    • Nieuwenhuis, Edward E S;
    • van den Brink, Stieneke;
    • Clevers, Hans;
    • van der Ent, Cornelis K;
    • Middendorp, Sabine;
    • Beekman, Jeffrey M
    Publication type:
    Article

  • Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids.

    Published in:
    PLoS Biology, 2018, v. 16, n. 8, p. 1, doi. 10.1371/journal.pbio.2004986
    By:
    • Michalak, Ewa M.;
    • Milevskiy, Michael J. G.;
    • Joyce, Rachel M.;
    • Dekkers, Johanna F.;
    • Jamieson, Paul R.;
    • Pal, Bhupinder;
    • Dawson, Caleb A.;
    • Hu, Yifang;
    • Orkin, Stuart H.;
    • Alexander, Warren S.;
    • Lindeman, Geoffrey J.;
    • Smyth, Gordon K.;
    • Visvader, Jane E.
    Publication type:
    Article

  • rAAV-CFTRΔR rescues the cystic fibrosis phenotype in human intestinal organoids and CF mice.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2016, v. 193, n. 3, p. E1, doi. 10.1164/rccm.201505-0914oc
    By:
    • Vidović, Dragana;
    • Carlon, Marianne S.;
    • da Cunha, Mélanie F.;
    • Dekkers, Johanna F.;
    • Hollenhorst, Monika I.;
    • Bijvelds, Marcel J. C.;
    • Ramalho, Anabela S.;
    • Van den Haute, Chris;
    • Ferrante, Marc;
    • Baekelandt, Veerle;
    • Janssens, Hettie M.;
    • De Boeck, Kris;
    • Sermet-Gaudelus, Isabelle;
    • de Jonge, Hugo R.;
    • Gijsbers, Rik;
    • Beekman, Jeffrey M.;
    • Edelman, Aleksander;
    • Debyser, Zeger
    Publication type:
    Article

  • rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice.

    Published in:
    2016
    By:
    • Vidović, Dragana;
    • Carlon, Marianne S.;
    • da Cunha, Mélanie F.;
    • Dekkers, Johanna F.;
    • Hollenhorst, Monika I.;
    • Bijvelds, Marcel J. C.;
    • Ramalho, Anabela S.;
    • Van den Haute, Chris;
    • Ferrante, Marc;
    • Baekelandt, Veerle;
    • Janssens, Hettie M.;
    • De Boeck, Kris;
    • Sermet-Gaudelus, Isabelle;
    • de Jonge, Hugo R.;
    • Gijsbers, Rik;
    • Beekman, Jeffrey M.;
    • Edelman, Aleksander;
    • Debyser, Zeger
    Publication type:
    journal article

  • In vivo genome‐editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis.

    Published in:
    Molecular Oncology, 2022, v. 16, n. 5, p. 1119, doi. 10.1002/1878-0261.13179
    By:
    • Heitink, Luuk;
    • Whittle, James R.;
    • Vaillant, François;
    • Capaldo, Bianca D.;
    • Dekkers, Johanna F.;
    • Dawson, Caleb A.;
    • Milevskiy, Michael J. G.;
    • Surgenor, Elliot;
    • Tsai, Minhsuang;
    • Chen, Huei‐Rong;
    • Christie, Michael;
    • Chen, Yunshun;
    • Smyth, Gordon K.;
    • Herold, Marco J.;
    • Strasser, Andreas;
    • Lindeman, Geoffrey J.;
    • Visvader, Jane E.
    Publication type:
    Article

  • Long‐term expanding human airway organoids for disease modeling.

    Published in:
    EMBO Journal, 2019, v. 38, n. 4, p. 1, doi. 10.15252/embj.2018100300
    By:
    • Sachs, Norman;
    • Papaspyropoulos, Angelos;
    • Zomer‐van Ommen, Domenique D;
    • Heo, Inha;
    • Böttinger, Lena;
    • Klay, Dymph;
    • Weeber, Fleur;
    • Huelsz‐Prince, Guizela;
    • Iakobachvili, Nino;
    • Amatngalim, Gimano D;
    • Ligt, Joep;
    • Hoeck, Arne;
    • Proost, Natalie;
    • Viveen, Marco C;
    • Lyubimova, Anna;
    • Teeven, Luc;
    • Derakhshan, Sepideh;
    • Korving, Jeroen;
    • Begthel, Harry;
    • Dekkers, Johanna F
    Publication type:
    Article

  • Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.

    Published in:
    Science Translational Medicine, 2016, v. 8, n. 344, p. 1, doi. 10.1126/scitranslmed.aad8278
    By:
    • Dekkers, Johanna F.;
    • Berkers, Gitte;
    • Kruisselbrink, Evelien;
    • Vonk, Annelotte;
    • de Jonge, Hugo R.;
    • Janssens, Hettie M.;
    • Bronsveld, Inez;
    • van de Graaf, Eduard A.;
    • Nieuwenhuis, Edward E. S.;
    • Houwen, Roderick H. J.;
    • Vleggaar, Frank P.;
    • Escher, Johanna C.;
    • de Rijke, Yolanda B.;
    • Majoor, Christof J.;
    • Heijerman, Harry G. M.;
    • de Winter–de Groot, Karin M.;
    • Clevers, Hans;
    • van der Ent, Cornelis K.;
    • Beekman, Jeffrey M.
    Publication type:
    Article

  • Anti-GD2-IRDye800CW as a targeted probe for fluorescence-guided surgery in neuroblastoma.

    Published in:
    Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-74464-4
    By:
    • Wellens, Lianne M.;
    • Deken, Marion M.;
    • Sier, Cornelis F. M.;
    • Johnson, Hannah R.;
    • de la Jara Ortiz, Fàtima;
    • Bhairosingh, Shadhvi S.;
    • Houvast, Ruben D.;
    • Kholosy, Waleed M.;
    • Baart, Victor M.;
    • Pieters, Annique M. M. J.;
    • de Krijger, Ronald R.;
    • Molenaar, Jan J.;
    • Wehrens, Ellen J.;
    • Dekkers, Johanna F.;
    • Wijnen, Marc H. W. A.;
    • Vahrmeijer, Alexander L.;
    • Rios, Anne C.
    Publication type:
    Article

  • Transplantable programmed death ligand 1 expressing gastroids from gastric cancer prone Nfkb1<sup>−/−</sup> mice.

    Published in:
    Cell Death & Disease, 2021, v. 12, n. 12, p. 1, doi. 10.1038/s41419-021-04376-2
    By:
    • Low, Jun T.;
    • Ho, Gwo-Yaw;
    • Scott, Mark;
    • Tan, Chin Wee;
    • Whitehead, Lachlan;
    • Barber, Kathy;
    • Yip, Hon Y. K.;
    • Dekkers, Johanna F.;
    • Hirokawa, Yumiko;
    • Silke, John;
    • Burgess, Antony W.;
    • Strasser, Andreas;
    • Putoczki, Tracy L.;
    • O'Reilly, Lorraine A.
    Publication type:
    Article

  • Modulation of the Maladaptive Stress Response to Manage Diseases of Protein Folding.

    Published in:
    PLoS Biology, 2014, v. 12, n. 11, p. 1, doi. 10.1371/journal.pbio.1001998
    By:
    • Roth, Daniela Martino;
    • Hutt, Darren M.;
    • Tong, Jiansong;
    • Bouchecareilh, Marion;
    • Wang, Ning;
    • Seeley, Theo;
    • Dekkers, Johanna F.;
    • Beekman, Jeffrey M.;
    • Garza, Dan;
    • Drew, Lawrence;
    • Masliah, Eliezer;
    • Morimoto, Richard I.;
    • Balch, William E.
    Publication type:
    Article

  • BEHAV3D: a 3D live imaging platform for comprehensive analysis of engineered T cell behavior and tumor response.

    Published in:
    Nature Protocols, 2024, v. 19, n. 7, p. 2052, doi. 10.1038/s41596-024-00972-6
    By:
    • Alieva, Maria;
    • Barrera Román, Mario;
    • de Blank, Sam;
    • Petcu, Diana;
    • Zeeman, Amber L.;
    • Dautzenberg, Noël M. M.;
    • Cornel, Annelisa M.;
    • van de Ven, Cesca;
    • Pieters, Rob;
    • den Boer, Monique L.;
    • Nierkens, Stefan;
    • Calkoen, Friso G. J.;
    • Clevers, Hans;
    • Kuball, Jürgen;
    • Sebestyén, Zsolt;
    • Wehrens, Ellen J.;
    • Dekkers, Johanna F.;
    • Rios, Anne C.
    Publication type:
    Article

  • Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids.

    Published in:
    Nature Protocols, 2021, v. 16, n. 4, p. 1936, doi. 10.1038/s41596-020-00474-1
    By:
    • Dekkers, Johanna F.;
    • van Vliet, Esmée J.;
    • Sachs, Norman;
    • Rosenbluth, Jennifer M.;
    • Kopper, Oded;
    • Rebel, Heggert G.;
    • Wehrens, Ellen J.;
    • Piani, Carol;
    • Visvader, Jane E.;
    • Verissimo, Carla S.;
    • Boj, Sylvia F.;
    • Brugge, Joan S.;
    • Clevers, Hans;
    • Rios, Anne C.
    Publication type:
    Article

  • High-resolution 3D imaging of fixed and cleared organoids.

    Published in:
    Nature Protocols, 2019, v. 14, n. 6, p. 1756, doi. 10.1038/s41596-019-0160-8
    By:
    • Dekkers, Johanna F.;
    • Alieva, Maria;
    • Wellens, Lianne M.;
    • Ariese, Hendrikus C. R.;
    • Jamieson, Paul R.;
    • Vonk, Annelotte M.;
    • Amatngalim, Gimano D.;
    • Hu, Huili;
    • Oost, Koen C.;
    • Snippert, Hugo J. G.;
    • Beekman, Jeffrey M.;
    • Wehrens, Ellen J.;
    • Visvader, Jane E.;
    • Clevers, Hans;
    • Rios, Anne C.
    Publication type:
    Article

  • Mechanism-based corrector combination restores ΔF508-CFTR folding and function.

    Published in:
    Nature Chemical Biology, 2013, v. 9, n. 7, p. 444, doi. 10.1038/nchembio.1253
    By:
    • Okiyoneda, Tsukasa;
    • Veit, Guido;
    • Dekkers, Johanna F;
    • Bagdany, Miklos;
    • Soya, Naoto;
    • Xu, Haijin;
    • Roldan, Ariel;
    • Verkman, Alan S;
    • Kurth, Mark;
    • Simon, Agnes;
    • Hegedus, Tamas;
    • Beekman, Jeffrey M;
    • Lukacs, Gergely L
    Publication type:
    Article

  • Modeling Breast Cancer Using CRISPR-Cas9-Mediated Engineering of Human Breast Organoids.

    Published in:
    2020
    By:
    • Dekkers, Johanna F;
    • Whittle, James R;
    • Vaillant, François;
    • Chen, Huei-Rong;
    • Dawson, Caleb;
    • Liu, Kevin;
    • Geurts, Maarten H;
    • Herold, Marco J;
    • Clevers, Hans;
    • Lindeman, Geoffrey J;
    • Visvader, Jane E
    Publication type:
    journal article