Works by Dekker, Niek

Results: 19

Exosomes, microvesicles, and other extracellular vesicles—a Keystone Symposia report.

Published in:

Annals of the New York Academy of Sciences, 2023, v. 1523, n. 1, p. 24, doi. 10.1111/nyas.14974

By:

Cable, Jennifer;
Witwer, Kenneth W.;
Coffey, Robert J.;
Milosavljevic, Aleksandar;
von Lersner, Ariana K.;
Jimenez, Lizandra;
Pucci, Ferdinando;
Barr, Maureen M.;
Dekker, Niek;
Barman, Bahnisikha;
Humphrys, Daniel;
Williams, Justin;
de Palma, Michele;
Guo, Wei;
Bastos, Nuno;
Hill, Andrew F.;
Levy, Efrat;
Hantak, Michael P.;
Crewe, Clair;
Aikawa, Elena

Publication type:

Article

Solution structure of the POU-specific DNA-binding domain of Oct-1.

Published in:

Nature, 1993, v. 362, n. 6423, p. 852, doi. 10.1038/362852a0

By:

Dekker, Niek;
Cox, Michel

Publication type:

Article

Creating Designer Engineered Extracellular Vesicles for Diverse Ligand Display, Target Recognition, and Controlled Protein Loading and Delivery.

Published in:

Advanced Science, 2023, v. 10, n. 34, p. 1, doi. 10.1002/advs.202304389

By:

Ivanova, Alena;
Badertscher, Lukas;
O'Driscoll, Gwen;
Bergman, Joakim;
Gordon, Euan;
Gunnarsson, Anders;
Johansson, Camilla;
Munson, Michael J.;
Spinelli, Cristiana;
Torstensson, Sara;
Vilén, Liisa;
Voirel, Andrei;
Wiseman, John;
Rak, Janusz;
Dekker, Niek;
Lázaro‐Ibáñez, Elisa

Publication type:

Article

Engineered Cas9 extracellular vesicles as a novel gene editing tool.

Published in:

Journal of Extracellular Vesicles, 2022, v. 11, n. 5, p. 1, doi. 10.1002/jev2.12225

By:

Osteikoetxea, Xabier;
Silva, Andreia;
Lázaro‐Ibáñez, Elisa;
Salmond, Nikki;
Shatnyeva, Olga;
Stein, Josia;
Schick, Jan;
Wren, Stephen;
Lindgren, Julia;
Firth, Mike;
Madsen, Alexandra;
Mayr, Lorenz M.;
Overman, Ross;
Davies, Rick;
Dekker, Niek

Publication type:

Article

Quantification of protein cargo loading into engineered extracellular vesicles at single‐vesicle and single‐molecule resolution.

Published in:

Journal of Extracellular Vesicles, 2021, v. 10, n. 10, p. 1, doi. 10.1002/jev2.12130

By:

Silva, Andreia M.;
Lázaro‐Ibáñez, Elisa;
Gunnarsson, Anders;
Dhande, Aditya;
Daaboul, George;
Peacock, Ben;
Osteikoetxea, Xabier;
Salmond, Nikki;
Friis, Kristina Pagh;
Shatnyeva, Olga;
Dekker, Niek

Publication type:

Article

Chemogenetics defines a short-chain fatty acid receptor gut--brain axis.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.73777

By:

Barki, Natasja;
Bolognini, Daniele;
Börjesson, Ulf;
Jenkins, Laura;
Riddell, John;
Hughes, David I.;
Ulven, Trond;
Hudson, Brian D.;
Ulven, Elisabeth Rexen;
Dekker, Niek;
Tobin, Andrew B.;
Milligan, Graeme

Publication type:

Article

Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis.

Published in:

Cardiovascular Research, 2022, v. 118, n. 2, p. 489, doi. 10.1093/cvr/cvab076

By:

Liu, Cong;
Schönke, Milena;
Zhou, Enchen;
Li, Zhuang;
Kooijman, Sander;
Boon, Mariëtte R;
Larsson, Mikael;
Wallenius, Kristina;
Dekker, Niek;
Barlind, Louise;
Peng, Xiao-Rong;
Wang, Yanan;
Rensen, Patrick C N

Publication type:

Article

Outer-membrane phospholipase A: known structure, unknown biological function.

Published in:

Molecular Microbiology, 2000, v. 35, n. 4, p. 711, doi. 10.1046/j.1365-2958.2000.01775.x

By:

Dekker, Niek

Publication type:

Article

Molecular tuning of farnesoid X receptor partial agonism.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10853-2

By:

Merk, Daniel;
Sreeramulu, Sridhar;
Kudlinzki, Denis;
Saxena, Krishna;
Linhard, Verena;
Gande, Santosh L.;
Hiller, Fabian;
Lamers, Christina;
Nilsson, Ewa;
Aagaard, Anna;
Wissler, Lisa;
Dekker, Niek;
Bamberg, Krister;
Schubert-Zsilavecz, Manfred;
Schwalbe, Harald

Publication type:

Article

Cover Picture: X-ray Structural Analysis of Tau-Tubulin Kinase 1 and Its Interactions with Small Molecular Inhibitors (ChemMedChem 11/2013).

Published in:

ChemMedChem, 2013, v. 8, n. 11, p. 1721, doi. 10.1002/cmdc.201390045

By:

Xue, Yafeng;
Wan, Paul T.;
Hillertz, Per;
Schweikart, Fritz;
Zhao, Yanlong;
Wissler, Lisa;
Dekker, Niek

Publication type:

Article

X-ray Structural Analysis of Tau-Tubulin Kinase 1 and Its Interactions with Small Molecular Inhibitors.

Published in:

ChemMedChem, 2013, v. 8, n. 11, p. 1846, doi. 10.1002/cmdc.201300274

By:

Xue, Yafeng;
Wan, Paul T.;
Hillertz, Per;
Schweikart, Fritz;
Zhao, Yanlong;
Wissler, Lisa;
Dekker, Niek

Publication type:

Article

Barcoded Hybrids of Extracellular Vesicles and Lipid Nanoparticles for Multiplexed Analysis of Tissue Distribution.

Published in:

Advanced Science, 2025, v. 12, n. 10, p. 1, doi. 10.1002/advs.202407850

By:

Ivanova, Alena;
Chalupska, Renata;
Louro, Ana Filipa;
Firth, Mike;
González‐King Garibotti, Hernán;
Hultin, Leif;
Kohl, Franziska;
Lázaro‐Ibáñez, Elisa;
Lindgren, Julia;
Musa, Gentian;
Oude Blenke, Erik;
Silva, Andreia M.;
Szeponik, Louis;
Taylor, Agnes;
Viken, Ida;
Wang, Xiaoqin;
Jennbacken, Karin;
Wiseman, John;
Dekker, Niek

Publication type:

Article

Incorporation of an unnatural amino acid in the active site of porcine pancreatic phospholipase A2. Substitution of histidine by l,2,4-triazole-3-alanine yields an enzyme with high activity at acidic pH.

Published in:

Protein Engineering, 1996, v. 9, n. 4, p. 345, doi. 10.1093/protein/9.4.345

By:

Beiboer, Sigrid H.W.;
Berg, Bert van den;
Dekker, Niek;
Cox, Ruud C.;
Verheij, Hubertus M.

Publication type:

Article

Human pancreatic islet-derived extracellular vesicles modulate insulin expression in 3D-differentiating iPSC clusters.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187665

By:

Ribeiro, Diana;
Andersson, Eva-Marie;
Heath, Nikki;
Persson-kry, Anette;
Collins, Richard;
Hicks, Ryan;
Dekker, Niek;
Forslöw, Anna

Publication type:

Article

G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent.

Published in:

Bioscience Reports, 2015, v. 35, n. 2, p. 1, doi. 10.1042/BSR20140171

By:

Jamshad, Mohammed;
Charlton, Jack;
Yu-Pin Lin;
Routledge, Sarah J.;
Bawa, Zharain;
Knowles, Timothy J.;
Overduin, Michael;
Dekker, Niek;
Dafforn, Tim R.;
Bill, Roslyn M.;
Poyner, David R.;
Wheatley, Mark

Publication type:

Article

Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site.

Published in:

EMBO Journal, 2001, v. 20, n. 18, p. 5033, doi. 10.1093/emboj/20.18.5033

By:

Vandeputte-Rutten, Lucy;
Kramer, R. Arjen;
Kroon, Jan;
Dekker, Niek;
Egmond, Maarten R.;
Gros, Piet

Publication type:

Article

Oncostatin M-Enriched Small Extracellular Vesicles Derived from Mesenchymal Stem Cells Prevent Isoproterenol-Induced Fibrosis and Enhance Angiogenesis.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 7, p. 6467, doi. 10.3390/ijms24076467

By:

Tejedor, Sandra;
Buigues, Marc;
González-King, Hernán;
Silva, Andreia M.;
García, Nahuel Aquiles;
Dekker, Niek;
Sepúlveda, Pilar

Publication type:

Article

Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibition.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-01504-0

By:

Kennedy, Amanda J.;
Sundström, Linda;
Geschwindner, Stefan;
Poon, Eunice K. Y.;
Jiang, Yuhong;
Chen, Rongfeng;
Cooke, Rob;
Johnstone, Shawn;
Madin, Andrew;
Lim, Junxian;
Liu, Qingqi;
Lohman, Rink-Jan;
Nordqvist, Anneli;
Fridén-Saxin, Maria;
Yang, Wenzhen;
Brown, Dean G.;
Fairlie, David P.;
Dekker, Niek

Publication type:

Article

In vivo phage display identifies novel peptides for cardiac targeting.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-62953-9

By:

Ivanova, Alena;
Kohl, Franziska;
González-King Garibotti, Hernán;
Chalupska, Renata;
Cvjetkovic, Aleksander;
Firth, Mike;
Jennbacken, Karin;
Martinsson, Sofia;
Silva, Andreia M.;
Viken, Ida;
Wang, Qing-Dong;
Wiseman, John;
Dekker, Niek

Publication type:

Article