Works by Defronzo RA

Results: 23

Relationship of baseline HbA1c and efficacy of current glucose-lowering therapies: a meta-analysis of randomized clinical trials.
Published in:
2010
By:
- DeFronzo RA;
- Stonehouse AH;
- Han J;
- Wintle ME
Publication type:
Journal Article
Strong association between insulin resistance in liver and skeletal muscle in non-diabetic subjects.
Published in:
2008
By:
- Abdul-Ghani MA;
- Matsuda M;
- DeFronzo RA
Publication type:
Journal Article
The relationship between {beta}-cell function and glycated hemoglobin: results from the veterans administration genetic epidemiology study.
Published in:
2011
By:
- Kanat M;
- Winnier D;
- Norton L;
- Arar N;
- Jenkinson C;
- Defronzo RA;
- Abdul-Ghani MA;
- Kanat, Mustafa;
- Winnier, Diedre;
- Norton, Luke;
- Arar, Nazik;
- Jenkinson, Chris;
- Defronzo, Ralph A;
- Abdul-Ghani, Muhammad A
Publication type:
journal article
Effects of exenatide plus rosiglitazone on beta-cell function and insulin sensitivity in subjects with type 2 diabetes on metformin.
Published in:
2010
By:
- DeFronzo RA;
- Triplitt C;
- Qu Y;
- Lewis MS;
- Maggs D;
- Glass LC;
- DeFronzo, Ralph A;
- Triplitt, Curtis;
- Qu, Yongming;
- Lewis, Michelle S;
- Maggs, David;
- Glass, Leonard C
Publication type:
journal article
Skeletal muscle insulin resistance is the primary defect in type 2 diabetes.
Published in:
2009
By:
- DeFronzo RA;
- Tripathy D;
- DeFronzo, Ralph A;
- Tripathy, Devjit
Publication type:
journal article
Oral disposition index predicts the development of future diabetes above and beyond fasting and 2-h glucose levels: response to Utzschneider et al.
Published in:
2009
By:
- DeFronzo RA;
- Abdul-Ghani MA
Publication type:
Journal Article
Fasting versus postload plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia Study.
Published in:
2009
By:
- Abdul-Ghani MA;
- Lyssenko V;
- Tuomi T;
- Defronzo RA;
- Groop L;
- Abdul-Ghani, Muhammad A;
- Lyssenko, Valeriya;
- Tuomi, Tiinamaija;
- DeFronzo, Ralph A;
- Groop, Leif
Publication type:
journal article
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor alogliptin in patients with type 2 diabetes and inadequate glycemic control: a randomized, double-blind, placebo-controlled study.
Published in:
2008
By:
- DeFronzo RA;
- Fleck PR;
- Wilson CA;
- Mekki Q;
- Alogliptin Study 010 Group;
- DeFronzo, Ralph A;
- Fleck, Penny R;
- Wilson, Craig A;
- Mekki, Qais
Publication type:
journal article
Dysfunctional fat cells, lipotoxicity and type 2 diabetes.
Published in:
2004
By:
- DeFronzo RA
Publication type:
Journal Article
Efficacy and tolerability of the DPP-4 inhibitor alogliptin combined with pioglitazone, in metformin-treated patients with type 2 diabetes.
Published in:
2012
By:
- DeFronzo RA;
- Burant CF;
- Fleck P;
- Wilson C;
- Mekki Q;
- Pratley RE
Publication type:
Journal Article
Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study.
Published in:
2007
By:
- Sriwijitkamol A;
- Coletta DK;
- Wajcberg E;
- Balbontin GB;
- Reyna SM;
- Barrientes J;
- Eagan PA;
- Jenkinson CP;
- Cersosimo E;
- Defronzo RA;
- Sakamoto K;
- Musi N;
- Sriwijitkamol, Apiradee;
- Coletta, Dawn K;
- Wajcberg, Estela;
- Balbontin, Gabriela B;
- Reyna, Sara M;
- Barrientes, John;
- Eagan, Phyllis A;
- Jenkinson, Christopher P
Publication type:
journal article
Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance: results from the Veterans Administration Genetic Epidemiology Study.
Published in:
2006
By:
- Abdul-Ghani MA;
- Jenkinson CP;
- Richardson DK;
- Tripathy D;
- DeFronzo RA;
- Abdul-Ghani, Muhammad A;
- Jenkinson, Christopher P;
- Richardson, Dawn K;
- Tripathy, Devjit;
- DeFronzo, Ralph A
Publication type:
journal article
Reduced skeletal muscle inhibitor of kappaB beta content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training.
Published in:
2006
By:
- Sriwijitkamol A;
- Christ-Roberts C;
- Berria R;
- Eagan P;
- Pratipanawatr T;
- DeFronzo RA;
- Mandarino LJ;
- Musi N;
- Sriwijitkamol, Apiradee;
- Christ-Roberts, Christine;
- Berria, Rachele;
- Eagan, Phyllis;
- Pratipanawatr, Thongchai;
- DeFronzo, Ralph A;
- Mandarino, Lawrence J;
- Musi, Nicolas
Publication type:
journal article
Pioglitazone and alogliptin combination therapy in type 2 diabetes: a pathophysiologically sound treatment.
Published in:
2010
By:
- Triplitt C;
- Cersosimo E;
- DeFronzo RA;
- Triplitt, Curtis;
- Cersosimo, Eugenio;
- DeFronzo, Ralph A
Publication type:
journal article
Muscle and liver insulin resistance indexes derived from the oral glucose tolerance test.
Published in:
2007
By:
- Bastard J;
- Faraj M;
- Karelis AD;
- Lavasseur J;
- Garrel D;
- Prud'Homme D;
- Rabasa-Lhoret R;
- Abdul-Ghani MA;
- Matsuda M;
- Balas B;
- DeFronzo RA
Publication type:
Journal Article
Impaired fasting glucose and impaired glucose tolerance: implications for care.
Published in:
2007
By:
- Nathan DM;
- Davidson MB;
- DeFronzo RA;
- Heine RJ;
- Henry RR;
- Pratley R;
- Zinman B
Publication type:
Journal Article
The effect of pioglitazone on the liver: role of adiponectin.
Published in:
2006
By:
- Gastaldelli A;
- Miyazaki Y;
- Mahankali A;
- Berria R;
- Pettiti M;
- Buzzigoli E;
- Ferrannini E;
- DeFronzo RA
Publication type:
Journal Article
Contributions of ß-cell dysfunction and insulin resistance to the pathogenesis of impaired glucose tolerance and impaired fasting glucose.
Published in:
2006
By:
- Abdul-Ghani MA;
- Tripathy D;
- DeFronzo RA
Publication type:
Journal Article
Improvement of glycemic control, triglycerides, and HDL cholesterol levels with muraglitazar, a dual (alpha/gamma) peroxisome proliferator-activated receptor activator, in patients with type 2 diabetes inadequately controlled with metformin monotherapy: A double-blind, randomized, pioglitazone-comparative study.
Published in:
2006
By:
- Kendall DM;
- Rubin CJ;
- Mohideen P;
- Ledeine J;
- Belder R;
- Gross J;
- Norwood P;
- O'Mahony M;
- Sall K;
- Sloan G;
- Roberts A;
- Fiedorek FT;
- DeFronzo RA
Publication type:
Journal Article
Efficacy of inhaled insulin in patients with type 2 diabetes not controlled with diet and exercise: a 12-week, randomized, comparative trial.
Published in:
2005
By:
- DeFronzo RA;
- Bergenstal RM;
- Cefalu WT;
- Pullman J;
- Lerman S;
- Bode BW;
- Phillips LS;
- Exubera Phase III Study Group;
- DeFronzo, Ralph A;
- Bergenstal, Richard M;
- Cefalu, William T;
- Pullman, John;
- Lerman, Sam;
- Bode, Bruce W;
- Phillips, Lawrence S
Publication type:
journal article
Bromocriptine: a novel approach to the treatment of type 2 diabetes.
Published in:
2000
By:
- Pijl H;
- Ohashi S;
- Matsuda M;
- Miyazaki Y;
- Mahankali A;
- Kumar V;
- Pipek R;
- Iozzo P;
- Lancaster JL;
- Cincotta AH;
- DeFronzo RA;
- Pijl, H;
- Ohashi, S;
- Matsuda, M;
- Miyazaki, Y;
- Mahankali, A;
- Kumar, V;
- Pipek, R;
- Iozzo, P;
- Lancaster, J L
Publication type:
journal article
Why Do SGLT2 inhibitors inhibit only 30-50% of renal glucose reabsorption in humans?
Published in:
2012
By:
- Liu JJ;
- Lee T;
- Defronzo RA;
- Liu, Jiwen Jim;
- Lee, TaeWeon;
- DeFronzo, Ralph A
Publication type:
journal article
Distinct β-cell defects in impaired fasting glucose and impaired glucose tolerance.
Published in:
2012
By:
- Kanat M;
- Mari A;
- Norton L;
- Winnier D;
- Defronzo RA;
- Jenkinson C;
- Abdul-Ghani MA;
- Kanat, Mustafa;
- Mari, Andrea;
- Norton, Luke;
- Winnier, Diedre;
- DeFronzo, Ralph A;
- Jenkinson, Chris;
- Abdul-Ghani, Muhammad A
Publication type:
journal article