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Use of Single-Injection Recombinant Vesicular Stomatitis Virus Vaccine to Protect Nonhuman Primates Against Lethal Nipah Virus Disease.
Published in:
2019
By:
- Mire, Chad E.;
- Geisbert, Joan B.;
- Agans, Krystle N.;
- Versteeg, Krista M.;
- Deer, Daniel J.;
- Satterfield, Benjamin A.;
- Fenton, Karla A.;
- Geisbert, Thomas W.
Publication type:
journal article
Crimean-Congo hemorrhagic fever virus strains Hoti and Afghanistan cause viremia and mild clinical disease in cynomolgus monkeys.
Published in:
PLoS Neglected Tropical Diseases, 2020, v. 14, n. 8, p. 1, doi. 10.1371/journal.pntd.0008637
By:
- Cross, Robert W.;
- Prasad, Abhishek N.;
- Borisevich, Viktoriya;
- Geisbert, Joan B.;
- Agans, Krystle N.;
- Deer, Daniel J.;
- Fenton, Karla A.;
- Geisbert, Thomas W.
Publication type:
Article
Natural history of nonhuman primates after conjunctival exposure to Ebola virus.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-31027-7
By:
- Cross, Robert W.;
- Prasad, Abhishek N.;
- Woolsey, Courtney B.;
- Agans, Krystle N.;
- Borisevich, Viktoriya;
- Dobias, Natalie S.;
- Comer, Jason E.;
- Deer, Daniel J.;
- Geisbert, Joan B.;
- Rasmussen, Angela L.;
- Lipkin, Walter Ian;
- Fenton, Karla A.;
- Geisbert, Thomas W.
Publication type:
Article
Combination therapy protects macaques against advanced Marburg virus disease.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22132-0
By:
- Cross, Robert W.;
- Bornholdt, Zachary A.;
- Prasad, Abhishek N.;
- Borisevich, Viktoriya;
- Agans, Krystle N.;
- Deer, Daniel J.;
- Abelson, Dafna M.;
- Kim, Do H.;
- Shestowsky, William S.;
- Campbell, Lioudmila A.;
- Bunyan, Elaine;
- Geisbert, Joan B.;
- Fenton, Karla A.;
- Zeitlin, Larry;
- Porter, Danielle P.;
- Geisbert, Thomas W.
Publication type:
Article
Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus.
Published in:
Journal of Infectious Diseases, 2016, v. 214, p. S263, doi. 10.1093/infdis/jiw149
By:
- Mire, Chad E.;
- Geisbert, Joan B.;
- Agans, Krystle N.;
- Deer, Daniel J.;
- Fenton, Karla A.;
- Geisbert, Thomas W.
Publication type:
Article
Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death.
Published in:
2020
By:
- Cross, Robert W.;
- Rong Xu;
- Matassov, Demetrius;
- Hamm, Stefan;
- Latham, Theresa E.;
- Gerardi, Cheryl S.;
- Nowak, Rebecca M.;
- Geisbert, Joan B.;
- Ota-Setlik, Ayuko;
- Agans, Krystle N.;
- Luckay, Amara;
- Witko, Susan E.;
- Soukieh, Lena;
- Deer, Daniel J.;
- Mire, Chad E.;
- Feldmann, Heinz;
- Happi, Christian;
- Fenton, Karla A.;
- Eldridge, John H.;
- Geisbert, Thomas W.
Publication type:
journal article
Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death.
Published in:
Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 539, doi. 10.1172/JCI131958
By:
- Cross, Robert W.;
- Rong Xu;
- Matassov, Demetrius;
- Hamm, Stefan;
- Latham, Theresa E.;
- Gerardi, Cheryl S.;
- Nowak, Rebecca M.;
- Geisbert, Joan B.;
- Ayuko Ota-Setlik;
- Agans, Krystle N.;
- Luckay, Amara;
- Witko, Susan E.;
- Soukieh, Lena;
- Deer, Daniel J.;
- Mire, Chad E.;
- Feldmann, Heinz;
- Happi, Christian;
- Fenton, Karla A.;
- Eldridge, John H.;
- Geisbert, Thomas W.
Publication type:
Article
siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease.
Published in:
2017
By:
- Thi, Emily P.;
- Lee, Amy C. H.;
- Ursic-Bedoya, Raul;
- Robbins, Marjorie;
- Kondratowicz, Andrew S.;
- MacLachlan, Ian;
- Geisbert, Thomas W.;
- Mire, Chad E.;
- Geisbert, Joan B.;
- Agans, Krystle N.;
- Deer, Daniel J.;
- Cross, Robert W.;
- Fenton, Karla A.;
- Lee, Amy Ch
Publication type:
journal article
The Therapeutic Monoclonal Antibody Bamlanivimab Does Not Enhance SARS-CoV-2 Infection by FcR-Mediated Mechanisms.
Published in:
Pathogens, 2023, v. 12, n. 12, p. 1408, doi. 10.3390/pathogens12121408
By:
- Cross, Robert W.;
- Wiethoff, Christopher M.;
- Brown-Augsburger, Patricia;
- Berens, Shawn;
- Blackbourne, Jamie;
- Liu, Ling;
- Wu, Xiaohua;
- Tetreault, Jonathan;
- Dodd, Carter;
- Sina, Ramtin;
- Witcher, Derrick R.;
- Newcomb, Deanna;
- Frost, Denzil;
- Wilcox, Angela;
- Borisevich, Viktoriya;
- Agans, Krystle N.;
- Woolsey, Courtney;
- Prasad, Abhishek N.;
- Deer, Daniel J.;
- Geisbert, Joan B.
Publication type:
Article
Reversion of Ebolavirus Disease from a Single Intramuscular Injection of a Pan-Ebolavirus Immunotherapeutic.
Published in:
Pathogens, 2022, v. 11, n. 6, p. 655, doi. 10.3390/pathogens11060655
By:
- Kuang, Erin;
- Cross, Robert W.;
- McCavitt-Malvido, Maria;
- Abelson, Dafna M.;
- Borisevich, Viktoriya;
- Stuart, Lauren;
- Agans, Krystle N.;
- Mlakar, Neil;
- Marimuthu, Arumugapradeep;
- Deer, Daniel J.;
- Shestowsky, William S.;
- Kim, Do;
- Geisbert, Joan B.;
- Zeitlin, Larry;
- Moyer, Crystal L.;
- Roy, Chad J.;
- Geisbert, Thomas W.;
- Bornholdt, Zachary A.
Publication type:
Article
Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody.
Published in:
Science Translational Medicine, 2017, v. 9, n. 384, p. 1, doi. 10.1126/scitranslmed.aai8711
By:
- Mire, Chad E.;
- Geisbert, Joan B.;
- Borisevich, Viktoriya;
- Fenton, Karla A.;
- Agans, Krystle N.;
- Flyak, Andrew I.;
- Deer, Daniel J.;
- Steinkellner, Herta;
- Bohorov, Ognian;
- Bohorova, Natasha;
- Goodman, Charles;
- Hiatt, Andrew;
- Kim, Do H.;
- Pauly, Michael H.;
- Velasco, Jesus;
- Whaley, Kevin J.;
- Jr., James E. Crowe;
- Zeitlin, Larry;
- Geisbert, Thomas W.
Publication type:
Article
Intranasal exposure of African green monkeys to SARS-CoV-2 results in acute phase pneumonia with shedding and lung injury still present in the early convalescence phase.
Published in:
Virology Journal, 2020, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12985-020-01396-w
By:
- Cross, Robert W.;
- Agans, Krystle N.;
- Prasad, Abhishek N.;
- Borisevich, Viktoriya;
- Woolsey, Courtney;
- Deer, Daniel J.;
- Dobias, Natalie S.;
- Geisbert, Joan B.;
- Fenton, Karla A.;
- Geisbert, Thomas W.
Publication type:
Article
Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA.
Published in:
Science Translational Medicine, 2014, v. 6, n. 250, p. 1, doi. 10.1126/scitranslmed.3009706
By:
- Thi, Emily P.;
- Mire, Chad E.;
- Ursic-Bedoya, Raul;
- Geisbert, Joan B.;
- Lee, Amy C. H.;
- Agans, Krystle N.;
- Robbins, Marjorie;
- Deer, Daniel J.;
- Fenton, Karla A.;
- MacLachlan, Ian;
- Geisbert, Thomas W.
Publication type:
Article
Lipid nanoparticle siRNA treatment of Ebola-virus-Makona-infected nonhuman primates.
Published in:
Nature, 2015, v. 521, n. 7552, p. 362, doi. 10.1038/nature14442
By:
- Thi, Emily P.;
- Mire, Chad E.;
- Lee, Amy C. H.;
- Geisbert, Joan B.;
- Zhou, Joy Z.;
- Agans, Krystle N.;
- Snead, Nicholas M.;
- Deer, Daniel J.;
- Barnard, Trisha R.;
- Fenton, Karla A.;
- MacLachlan, Ian;
- Geisbert, Thomas W.
Publication type:
Article
Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates.
Published in:
Science Translational Medicine, 2024, v. 16, n. 741, p. 1, doi. 10.1126/scitranslmed.adl2055
By:
- Zeitlin, Larry;
- Cross, Robert W.;
- Woolsey, Courtney;
- West, Brandyn R.;
- Borisevich, Viktoriya;
- Agans, Krystle N.;
- Prasad, Abhishek N.;
- Deer, Daniel J.;
- Stuart, Lauren;
- McCavitt-Malvido, Maria;
- Kim, Do H.;
- Pettitt, James;
- Crowe Jr., James E.;
- Whaley, Kevin J.;
- Veesler, David;
- Dimitrov, Antony;
- Abelson, Dafna M.;
- Geisbert, Thomas W.;
- Broder, Christopher C.
Publication type:
Article
Long-term Prophylaxis Against Aerosolized Marburg Virus in Nonhuman Primates With an Afucosylated Monoclonal Antibody.
Published in:
Journal of Infectious Diseases, 2023, v. 228, p. S701, doi. 10.1093/infdis/jiad278
By:
- Abelson, Dafna;
- Barajas, Jennifer;
- Stuart, Lauren;
- Kim, Do;
- Marimuthu, Arumugapradeep;
- Hu, Chris;
- Yamamoto, Brent;
- Ailor, Eric;
- Whaley, Kevin J;
- Vu, Hong;
- Agans, Krystle N;
- Borisevich, Viktoriya;
- Deer, Daniel J;
- Dobias, Natalie S;
- Woolsey, Courtney;
- Prasad, Abhishek N;
- Peel, Jennifer E;
- Lawrence, William S;
- Cross, Robert W;
- Geisbert, Thomas W
Publication type:
Article
A Highly Attenuated Panfilovirus VesiculoVax Vaccine Rapidly Protects Nonhuman Primates Against Marburg Virus and 3 Species of Ebola Virus.
Published in:
Journal of Infectious Diseases, 2023, v. 228, p. S660, doi. 10.1093/infdis/jiad157
By:
- Woolsey, Courtney;
- Borisevich, Viktoriya;
- Agans, Krystle N;
- O'Toole, Rachel;
- Fenton, Karla A;
- Harrison, Mack B;
- Prasad, Abhishek N;
- Deer, Daniel J;
- Gerardi, Cheryl;
- Morrison, Nneka;
- Cross, Robert W;
- Eldridge, John H;
- Matassov, Demetrius;
- Geisbert, Thomas W
Publication type:
Article
Natural History of Nonhuman Primates After Oral Exposure to Ebola Virus Variant Makona.
Published in:
Journal of Infectious Diseases, 2023, v. 228, p. S571, doi. 10.1093/infdis/jiad225
By:
- Prasad, Abhishek N;
- Agans, Krystle N;
- Geisbert, Joan B;
- Borisevich, Viktoriya;
- Deer, Daniel J;
- Dobias, Natalie S;
- Comer, Jason E;
- Woolsey, Courtney;
- Fenton, Karla A;
- Geisbert, Thomas W;
- Cross, Robert W
Publication type:
Article
A Recombinant Vesicular Stomatitis Virus–Based Vaccine Provides Postexposure Protection Against Bundibugyo Ebolavirus Infection.
Published in:
Journal of Infectious Diseases, 2023, v. 228, p. S712, doi. 10.1093/infdis/jiad207
By:
- Woolsey, Courtney;
- Strampe, Jamie;
- Fenton, Karla A;
- Agans, Krystle N;
- Martinez, Jasmine;
- Borisevich, Viktoriya;
- Dobias, Natalie S;
- Deer, Daniel J;
- Geisbert, Joan B;
- Cross, Robert W;
- Connor, John H;
- Geisbert, Thomas W
Publication type:
Article
Pathogenesis of Aerosolized Ebola Virus Variant Makona in Nonhuman Primates.
Published in:
Journal of Infectious Diseases, 2023, v. 228, p. S604, doi. 10.1093/infdis/jiad137
By:
- Prasad, Abhishek N;
- Fenton, Karla A;
- Agans, Krystle N;
- Borisevich, Viktoriya;
- Woolsey, Courtney;
- Comer, Jason E;
- Dobias, Natalie S;
- Peel, Jennifer E;
- Deer, Daniel J;
- Geisbert, Joan B;
- Lawrence, William S;
- Cross, Robert W;
- Geisbert, Thomas W
Publication type:
Article
Resistance of Cynomolgus Monkeys to Nipah and Hendra Virus Disease Is Associated With Cell-Mediated and Humoral Immunity.
Published in:
2020
By:
- Prasad, Abhishek N;
- Woolsey, Courtney;
- Geisbert, Joan B;
- Agans, Krystle N;
- Borisevich, Viktoriya;
- Deer, Daniel J;
- Mire, Chad E;
- Cross, Robert W;
- Fenton, Karla A;
- Broder, Christopher C;
- Geisbert, Thomas W
Publication type:
journal article
An Intranasal Exposure Model of Lethal Nipah Virus Infection in African Green Monkeys.
Published in:
2020
By:
- Geisbert, Joan B;
- Borisevich, Viktoriya;
- Prasad, Abhishek N;
- Agans, Krystle N;
- Foster, Stephanie L;
- Deer, Daniel J;
- Cross, Robert W;
- Mire, Chad E;
- Geisbert, Thomas W;
- Fenton, Karla A
Publication type:
journal article
Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates.
Published in:
2018
By:
- Woolsey, Courtney;
- Geisbert, Joan B;
- Matassov, Demetrius;
- Agans, Krystle N;
- Borisevich, Viktoriya;
- Cross, Robert W;
- Deer, Daniel J;
- Fenton, Karla A;
- Eldridge, John H;
- Mire, Chad E;
- Geisbert, Thomas W
Publication type:
journal article
Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates.
Published in:
2018
By:
- Gilchuk, Pavlo;
- Mire, Chad E;
- Geisbert, Joan B;
- Agans, Krystle N;
- Deer, Daniel J;
- Cross, Robert W;
- Slaughter, James C;
- Flyak, Andrew I;
- Mani, Jeremy;
- Pauly, Michael H;
- Velasco, Jesus;
- Whaley, Kevin J;
- Zeitlin, Larry;
- Geisbert, Thomas W;
- Crowe, James E Jr
Publication type:
journal article
Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17446-4
By:
- Cross, Robert W.;
- Bornholdt, Zachary A.;
- Prasad, Abhishek N.;
- Geisbert, Joan B.;
- Borisevich, Viktoriya;
- Agans, Krystle N.;
- Deer, Daniel J.;
- Melody, Kevin;
- Fenton, Karla A.;
- Feldmann, Heinz;
- Sprecher, Armand;
- Zeitlin, Larry;
- Geisbert, Thomas W.
Publication type:
Article
A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge.
Published in:
PLoS Neglected Tropical Diseases, 2022, v. 16, n. 5, p. 1, doi. 10.1371/journal.pntd.0010433
By:
- Woolsey, Courtney;
- Cross, Robert W.;
- Agans, Krystle N.;
- Borisevich, Viktoriya;
- Deer, Daniel J.;
- Geisbert, Joan B.;
- Gerardi, Cheryl;
- Latham, Theresa E.;
- Fenton, Karla A.;
- Egan, Michael A.;
- Eldridge, John H.;
- Geisbert, Thomas W.;
- Matassov, Demetrius
Publication type:
Article

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