Works by Deeb, Dorrah

Results: 26

Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF- Îº B and Notch1 signaling.

Published in:

Journal of Neuro-Oncology, 2007, v. 84, n. 2, p. 147, doi. 10.1007/s11060-007-9364-9

By:

Xiaohua Gao;
Dorrah Deeb;
Hao Jiang;
Yongbo Liu;
Scott Dulchavsky;
Subhash Gautam

Publication type:

Article

Immunomodulatory activity of xanthohumol: inhibition of T cell proliferation, cell-mediated cytotoxicity and Th1 cytokine production through suppression of NF-κB.

Published in:

Immunopharmacology & Immunotoxicology, 2009, v. 31, n. 3, p. 477, doi. 10.1080/08923970902798132

By:

Gao, Xiaohua;
Deeb, Dorrah;
Liu, Yongbo;
Gautam, Sarita;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

Immunomodulatory Activity of Synthetic Triterpenoids: Inhibition of Lymphocyte Proliferation, Cell-Mediated Cytotoxicity, and Cytokine Gene Expression Through Suppression of NF-κB.

Published in:

Immunopharmacology & Immunotoxicology, 2008, v. 30, n. 3, p. 581, doi. 10.1080/08923970802135559

By:

Gao, Xiaohua;
Deeb, Dorrah;
Danyluk, Andrew;
Media, Joseph;
Liu, Yongbo;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

Mycotoxin verrucarin A inhibits proliferation and induces apoptosis in prostate cancer cells by inhibiting prosurvival Akt/NF-κB/mTOR signaling.

Published in:

Journal of Experimental Therapeutics & Oncology, 2016, v. 11, n. 4, p. 251

By:

Yongbo Liu;
Xiaohua Gao;
Deeb, Dorrah;
Yiguan Zhang;
Jiajiu Shaw;
Valeriote, Frederick A.;
Gautam, Subhash C.

Publication type:

Article

Anticancer agent pristimerin inhibits IL-2 induced activation of T lymphocytes.

Published in:

Journal of Experimental Therapeutics & Oncology, 2016, v. 11, n. 3, p. 181

By:

Yongbo Liu;
Xiaohua Gao;
Dorrah Deeb;
Yiguan Zhang;
Jiajiu Shaw;
Gautam, Subhash C.

Publication type:

Article

Role of telomerase in anticancer activity of pristimerin in prostate cancer cells.

Published in:

Journal of Experimental Therapeutics & Oncology, 2015, v. 11, n. 1, p. 41

By:

Yong Bo Liu;
Xiaohua Gao;
Deeb, Dorrah;
Pindolia, Kirit;
Gautam, Subhash C.

Publication type:

Article

Anticancer activity of pristimerin in ovarian carcinoma cells is mediated through the inhibition of prosurvival Akt/NF-κB/mTOR Signaling.

Published in:

Journal of Experimental Therapeutics & Oncology, 2014, v. 10, n. 4, p. 275

By:

Xiaohua Gao;
Yongbo Liu;
Deeb, Dorrah;
Arbab, Ali S.;
Gautam, Subhash C.

Publication type:

Article

Inhibition of cell proliferation and induction of apoptosis by CDDO-Me in pancreatic cancer cells is ROS-dependent.

Published in:

Journal of Experimental Therapeutics & Oncology, 2012, v. 10, n. 1, p. 51

By:

Deeb, Dorrah;
Xiaohua Gao;
Yong Bo Liu;
Gautam, Subhash C.

Publication type:

Article

Anticancer agent xanthohumol inhibits IL-2 induced signaling pathways involved in T cell proliferation.

Published in:

Journal of Experimental Therapeutics & Oncology, 2012, v. 10, n. 1, p. 1

By:

Yongbo Liu;
Xiaohua Gao;
Deeb, Dorrah;
Arbab, All S.;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

Role of reactive oxygen species (ROS) in CDDO-Me-mediated growth inhibition and apoptosis in colorectal cancer cells.

Published in:

Journal of Experimental Therapeutics & Oncology, 2011, v. 9, n. 2, p. 119

By:

Xiaohua Gao;
Deeb, Dorrah;
Liu, Patricia;
Yongbo Liu;
Arbab-Ali, Syed;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-κB/mTOR prosurvival signaling.

Published in:

International Journal of Oncology, 2016, v. 49, n. 3, p. 1139, doi. 10.3892/ijo.2016.3587

By:

DEEB, DORRAH;
XIAOHUA GAO;
YONGBO LIU;
YIGUAN ZHANG;
JIAJIU SHAW;
VALERIOTE, FREDERICK A.;
GAUTAM, SUBHASH C.

Publication type:

Article

CDDO-Me inhibits tumor growth and prevents recurrence of pancreatic ductal adenocarcinoma.

Published in:

International Journal of Oncology, 2015, v. 47, n. 6, p. 2100, doi. 10.3892/ijo.2015.3212

By:

XIAOHUA GAO;
DORRAH DEEB;
YONGBO LIU;
PATRICIA LIU;
YIGUAN ZHANG;
JIAJIU SHAW;
GAUTAM, SUBHASH C.

Publication type:

Article

Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin.

Published in:

International Journal of Oncology, 2014, v. 45, n. 4, p. 1735, doi. 10.3892/ijo.2014.2561

By:

YONG BO LIU;
XIAOHUA GAO;
DEEB, DORRAH;
BRIGOLIN, CHRIS;
YIGUAN ZHANG;
JIAJIU SHAW;
PINDOLIA, KIRIT;
GAUTAM, SUBHASH C.

Publication type:

Article

Oleanane Triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells by independently targeting pro-survival Akt and mTOR.

Published in:

Prostate, 2009, v. 69, n. 8, p. 851, doi. 10.1002/pros.20937

By:

Deeb, Dorrah;
Gao, Xiaohua;
Jiang, Hao;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

Prevention of Prostate Cancer with Oleanane Synthetic Triterpenoid CDDO-Me in the TRAMP Mouse Model of Prostate Cancer.

Published in:

Cancers, 2011, v. 3, n. 3, p. 3353, doi. 10.3390/cancers3033353

By:

Xiaohua Gao;
Deeb, Dorrah;
Yongbo Liu;
Arbab, Ali S.;
Divine, George W.;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

CDDO-Me: A Novel Synthetic Triterpenoid for the Treatment of Pancreatic Cancer.

Published in:

Cancers, 2010, v. 2, n. 4, p. 1779, doi. 10.3390/cancers2041779

By:

Deeb, Dorrah;
Xiaohua Gao;
Arbab, Ali S.;
Barton, Kenneth;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-κB and NF-κB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.

Published in:

Journal of Experimental Therapeutics & Oncology, 2008, v. 7, n. 1, p. 31

By:

Deeb, Dorrah;
Gao, Xiaohua;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

Vaccination with leukemia-loaded dendritic cells eradicates residual disease and prevent relapse.

Published in:

Journal of Experimental Therapeutics & Oncology, 2005, v. 5, n. 3, p. 183

By:

Deeb, Dorrah;
Xiaohua Gao;
Hao Jiang;
Divine, George;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

Curcumin differentially sensitizes malignant glioma cells to TRAIL/Apo2L-mediated apoptosis through activation of procaspases and release of cytochrome c from mitochondria.

Published in:

Journal of Experimental Therapeutics & Oncology, 2005, v. 5, n. 1, p. 39

By:

Xiaohua Gao;
Deeb, Dorrah;
Hao Jiang;
Liu, Yong B.;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

In vitro analysis of the antileukemic effect of tumor necrosis factor-α gene therapy with myeloid progenitor cells: the role of dendritic cells<sup>1</sup>.

Published in:

Journal of Experimental Therapeutics & Oncology, 2003, v. 3, n. 2, p. 62, doi. 10.1046/j.1359-4117.2003.01069.x

By:

Xu, Yong X.;
Deeb, Dorrah;
Gao, Xiaohua;
Janakiraman, Nalini;
Chapman, Robert A.;
Gautam, Subhash C.

Publication type:

Article

Bone Marrow-Derived Stromal Cells (BMSCs) Interact with Fibroblasts in Accelerating Wound Healing.

Published in:

Journal of Investigative Surgery, 2008, v. 21, n. 5, p. 270, doi. 10.1080/08941930802216831

By:

Dulchavsky, Deborah;
Gao, Xiaohua;
Liu, Yong Bo;
Deeb, Dorrah;
Arbab, Ali S.;
McIntosh, Kevin;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article

Inhibition of Telomerase Activity by Oleanane Triterpenoid CDDO-Me in Pancreatic Cancer Cells is ROS-Dependent.

Published in:

Molecules, 2013, v. 18, n. 3, p. 3250, doi. 10.3390/molecules18033250

By:

Deeb, Dorrah;
Xiaohua Gao;
Yongbo Liu;
Varma, Nadimpalli R. S.;
Arbab, Ali S.;
Gautam, Subhash C.

Publication type:

Article

Telomerase Reverse Transcriptase (TERT) is a Therapeutic Target of Oleanane Triterpenoid CDDO-Me in Prostate Cancer.

Published in:

Molecules, 2012, v. 17, n. 12, p. 14795, doi. 10.3390/molecules171214795

By:

Liu, Yongbo;
Gao, Xiaohua;
Deeb, Dorrah;
Arbab, Ali S.;
Gautam, Subhash C.

Publication type:

Article

Inhibition of hTERT in pancreatic cancer cells by pristimerin involves suppression of epigenetic regulators of gene transcription.

Published in:

Oncology Reports, 2017, v. 37, n. 3, p. 1914, doi. 10.3892/or.2017.5400

By:

DEEB, DORRAH;
XIAOHUA GAO;
YONG BO LIU;
YIGUAN ZHANG;
JIAJIU SHAW;
VALERIOTE, FREDERICK A.;
GAUTAM, SUBHASH C.

Publication type:

Article

Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.

Published in:

Oncology Reports, 2015, v. 34, n. 1, p. 518, doi. 10.3892/or.2015.3989

By:

DORRAH DEEB;
XIAOHUA GAO;
YONGBO LIU;
PINDOLIA, KIRIT;
GAUTAM, SUBHASH C.

Publication type:

Article

Synthetic triterpenoid CDDO prevents the progression and metastasis of prostate cancer in TRAMP mice by inhibiting survival signaling.

Published in:

Carcinogenesis, 2011, v. 32, n. 5, p. 757, doi. 10.1093/carcin/bgr030

By:

Deeb, Dorrah;
Gao, Xiaohua;
Liu, Yongbo;
Jiang, Daniel;
Divine, George W.;
Arbab, Ali S.;
Dulchavsky, Scott A.;
Gautam, Subhash C.

Publication type:

Article