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The Nitrobenzoxadiazole Derivative NBDHEX Behaves as Plasmodium falciparum Gametocyte Selective Inhibitor with Malaria Parasite Transmission Blocking Activity.
Published in:
Pharmaceuticals (14248247), 2022, v. 15, n. 2, p. 168, doi. 10.3390/ph15020168
By:
- Siciliano, Giulia;
- Di Paolo, Veronica;
- Rotili, Dante;
- Migale, Rossella;
- Pedini, Francesca;
- Casella, Marialuisa;
- Camerini, Serena;
- Dalzoppo, Daniele;
- Henderson, Rob;
- Huijs, Tonnie;
- Dechering, Koen J.;
- Mai, Antonello;
- Caccuri, Anna Maria;
- Lalle, Marco;
- Quintieri, Luigi;
- Alano, Pietro
Publication type:
Article
Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa.
Published in:
PLoS ONE, 2023, v. 18, n. 9, p. 1, doi. 10.1371/journal.pone.0284751
By:
- B. Henry, Noëlie;
- Soulama, Issiaka;
- S. Sermé, Samuel;
- Bolscher, Judith M.;
- T. G. Huijs, Tonnie;
- S. Coulibaly, Aboubacar;
- Sombié, Salif;
- Ouédraogo, Nicolas;
- Diarra, Amidou;
- Zongo, Soumanaba;
- Guelbéogo, Wamdaogo M.;
- Nébié, Issa;
- Sirima, Sodiomon B.;
- Tiono, Alfred B.;
- Pietro, Alano;
- Collins, Katharine A.;
- Dechering, Koen J.;
- Bousema, Teun
Publication type:
Article
Identification of Novel Regulators Associated With Early-Phase Osteoblast Differentiation.
Published in:
Journal of Bone & Mineral Research, 2004, v. 19, n. 6, p. 947, doi. 10.1359/JBMR.040216
By:
- de Jong, Diana S;
- Vaes, Bart LT;
- Dechering, Koen J;
- Feijen, Alie;
- Hendriks, Jose MA;
- Wehrens, Ron;
- Mummery, Christine L;
- van Zoelen, Everardus JJ;
- Olijve, Wiebe;
- Steegenga, Wilma T
Publication type:
Article
Gene Array Analysis of Bone Morphogenetic Protein Type I Receptor-Induced Osteoblast Differentiation.
Published in:
Journal of Bone & Mineral Research, 2003, v. 18, n. 7, p. 1177, doi. 10.1359/jbmr.2003.18.7.1177
By:
- Korchynskyi, Olexander;
- Dechering, Koen J;
- Sijbers, Anneke M;
- Olijve, Wiebe;
- Ten Dijke, Peter
Publication type:
Article
Comprehensive Microarray Analysis of Bone Morphogenetic Protein 2-Induced Osteoblast Differentiation Resulting in the Identification of Novel Markers for Bone Development.
Published in:
Journal of Bone & Mineral Research, 2002, v. 17, n. 12, p. 2106, doi. 10.1359/jbmr.2002.17.12.2106
By:
- Vaes, Bart L. T.;
- Dechering, Koen J.;
- Feijen, Alie;
- Hendriks, José M. A.;
- Lefèvre, Christophe;
- Mummery, Christine L.;
- Olijve, Wiebe;
- Van Zoelen, Everardus J. J.;
- Steegenga, Wilma T.
Publication type:
Article
A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes.
Published in:
Scientific Reports, 2015, p. 18704, doi. 10.1038/srep18704
By:
- Vos, Martijn W.;
- Stone, Will J. R.;
- Koolen, Karin M.;
- van Gemert, Geert-Jan;
- van Schaijk, Ben;
- Leroy, Didier;
- Sauerwein, Robert W.;
- Bousema, Teun;
- Dechering, Koen J.
Publication type:
Article
A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds.
Published in:
Scientific Reports, 2015, p. 16414, doi. 10.1038/srep16414
By:
- Lucantoni, Leonardo;
- Silvestrini, Francesco;
- Signore, Michele;
- Siciliano, Giulia;
- Eldering, Maarten;
- Dechering, Koen J.;
- Avery, Vicky M.;
- Alano, Pietro
Publication type:
Article
Generation of a Genetically Modified Chimeric Plasmodium falciparum Parasite Expressing Plasmodium vivax Circumsporozoite Protein for Malaria Vaccine Development.
Published in:
Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. N.PAG, doi. 10.3389/fcimb.2020.591046
By:
- Miyazaki, Yukiko;
- Marin-Mogollon, Catherin;
- Imai, Takashi;
- Mendes, António M.;
- van der Laak, Rianne;
- Sturm, Angelika;
- Geurten, Fiona J. A.;
- Miyazaki, Shinya;
- Chevalley-Maurel, Severine;
- Ramesar, Jai;
- Kolli, Surendra K.;
- Kroeze, Hans;
- van Schuijlenburg, Roos;
- Salman, Ahmed M.;
- Wilder, Brandon K.;
- Reyes-Sandoval, Arturo;
- Dechering, Koen J.;
- Prudêncio, Miguel;
- Janse, Chris J.;
- Khan, Shahid M.
Publication type:
Article
Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate—Tackling the Cocktail Challenge.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131456
By:
- Boes, Alexander;
- Spiegel, Holger;
- Voepel, Nadja;
- Edgue, Gueven;
- Beiss, Veronique;
- Kapelski, Stephanie;
- Fendel, Rolf;
- Scheuermayer, Matthias;
- Pradel, Gabriele;
- Bolscher, Judith M.;
- Behet, Marije C.;
- Dechering, Koen J.;
- Hermsen, Cornelus C.;
- Sauerwein, Robert W.;
- Schillberg, Stefan;
- Reimann, Andreas;
- Fischer, Rainer
Publication type:
Article
A scalable assessment of Plasmodium falciparum transmission in the standard membrane-feeding assay, using transgenic parasites expressing green fluorescent protein-luciferase.
Published in:
2014
By:
- Stone, Will J R;
- Churcher, Thomas S;
- Graumans, Wouter;
- van Gemert, Geert-Jan;
- Vos, Martijn W;
- Lanke, Kjerstin H W;
- van de Vegte-Bolmer, Marga G;
- Siebelink-Stoter, Rianne;
- Dechering, Koen J;
- Vaughan, Ashley M;
- Camargo, Nelly;
- Kappe, Stefan H I;
- Sauerwein, Robert W;
- Bousema, Teun
Publication type:
journal article
A Scalable Assessment of Plasmodium falciparum Transmission in the Standard Membrane-Feeding Assay, Using Transgenic Parasites Expressing Green Fluorescent Protein–Luciferase.
Published in:
Journal of Infectious Diseases, 2014, v. 210, n. 9, p. 1456, doi. 10.1093/infdis/jiu271
By:
- Stone, Will J. R.;
- Churcher, Thomas S.;
- Graumans, Wouter;
- van Gemert, Geert-Jan;
- Vos, Martijn W.;
- Lanke, Kjerstin H. W.;
- van de Vegte-Bolmer, Marga G.;
- Siebelink-Stoter, Rianne;
- Dechering, Koen J.;
- Vaughan, Ashley M.;
- Camargo, Nelly;
- Kappe, Stefan H. I.;
- Sauerwein, Robert W.;
- Bousema, Teun
Publication type:
Article
Delineation of amplification, hybridization andlocation effects in microarray data yieldsbetter-quality normalization.
Published in:
BMC Bioinformatics, 2010, v. 11, p. 156, doi. 10.1186/1471-2105-11-156
By:
- Hulsman, Marc;
- Mentink, Anouk;
- van Someren, Eugene P.;
- Dechering, Koen J.;
- de Boer, Jan;
- Reinders, Marcel J. T.
Publication type:
Article
Quantification of wild-type and radiation attenuated Plasmodium falciparum sporozoite motility in human skin.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49895-3
By:
- Winkel, Béatrice M. F.;
- de Korne, Clarize M.;
- van Oosterom, Matthias N.;
- Staphorst, Diego;
- Meijhuis, Mark;
- Baalbergen, Els;
- Ganesh, Munisha S.;
- Dechering, Koen J.;
- Vos, Martijn W.;
- Chevalley-Maurel, Séverine C.;
- Franke-Fayard, Blandine;
- van Leeuwen, Fijs W. B.;
- Roestenberg, Meta
Publication type:
Article
Distinct frequency‐distributions of homopolymeric DNA tracts in different genomes.
Published in:
Nucleic Acids Research, 1998, v. 26, n. 17, p. 4056, doi. 10.1093/nar/26.17.4056
By:
- Dechering, Koen J.;
- Cuelenaere, Koen;
- Konings, Ruud N. H.;
- Leunissen, Jack A. M.
Publication type:
Article
Epigenetics: DNA demethylation promotes skeletal myotube maturation.
Published in:
FASEB Journal, 2011, v. 25, n. 11, p. 3861, doi. 10.1096/fj.11-186122
By:
- Hupkes, Marlinda;
- Jonsson, Malin K. B.;
- Scheenen, Wim J.;
- van Rotterdam, Walter;
- Sotoca, Ana M.;
- van Someren, Eugene P.;
- van der Heyden, Marcel A. G.;
- van Veen, Toon A.;
- van Ravestein-van Os, Roselinde I.;
- Bauerschmidt, Susanne;
- Piek, Ester;
- Ypey, Dirk L.;
- van Zoelen, Everardus J.;
- Dechering, Koen J.
Publication type:
Article
Barcoded Asaia bacteria enable mosquito in vivo screens and identify novel systemic insecticides and inhibitors of malaria transmission.
Published in:
PLoS Biology, 2021, v. 19, n. 12, p. 1, doi. 10.1371/journal.pbio.3001426
By:
- Sturm, Angelika;
- Vos, Martijn W.;
- Henderson, Rob;
- Eldering, Maarten;
- Koolen, Karin M. J.;
- Sheshachalam, Avinash;
- Favia, Guido;
- Samby, Kirandeep;
- Herreros, Esperanza;
- Dechering, Koen J.
Publication type:
Article
An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1515-z
By:
- Miura, Kazutoyo;
- Stone, Will J. R.;
- Koolen, Karin M.;
- Deng, Bingbing;
- Zhou, Luwen;
- van Gemert, Geert-Jan;
- Locke, Emily;
- Morin, Merribeth;
- Bousema, Teun;
- Sauerwein, Robert W.;
- Long, Carole A.;
- Dechering, Koen J.
Publication type:
Article
Analysis of the dose-dependent stage-specific in vitro efficacy of a multi-stage malaria vaccine candidate cocktail.
Published in:
Malaria Journal, 2016, v. 15, p. 1, doi. 10.1186/s12936-016-1328-0
By:
- Boes, Alexander;
- Spiegel, Holger;
- Kastilan, Robin;
- Bethke, Susanne;
- Voepel, Nadja;
- Chudobová, Ivana;
- Bolscher, Judith M.;
- Dechering, Koen J.;
- Fendel, Rolf;
- Buyel, Johannes F.;
- Reimann, Andreas;
- Schillberg, Stefan;
- Fischer, Rainer
Publication type:
Article
Targeting Plasmodium PI(4)K to eliminate malaria.
Published in:
Nature, 2013, v. 504, n. 7479, p. 248, doi. 10.1038/nature12782
By:
- McNamara, Case W.;
- Lee, Marcus C. S.;
- Lim, Chek Shik;
- Lim, Siau Hoi;
- Roland, Jason;
- Nagle, Advait;
- Simon, Oliver;
- Yeung, Bryan K. S.;
- Chatterjee, Arnab K.;
- McCormack, Susan L.;
- Manary, Micah J.;
- Zeeman, Anne-Marie;
- Dechering, Koen J.;
- Kumar, T. R. Santha;
- Henrich, Philipp P.;
- Gagaring, Kerstin;
- Ibanez, Maureen;
- Kato, Nobutaka;
- Kuhen, Kelli L.;
- Fischli, Christoph
Publication type:
Article
A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages.
Published in:
Frontiers in Cellular & Infection Microbiology, 2019, v. 9, p. N.PAG, doi. 10.3389/fcimb.2019.00096
By:
- Marin-Mogollon, Catherin;
- Salman, Ahmed M.;
- Koolen, Karin M. J.;
- Bolscher, Judith M.;
- van Pul, Fiona J. A.;
- Miyazaki, Shinya;
- Imai, Takashi;
- Othman, Ahmad Syibli;
- Ramesar, Jai;
- van Gemert, Geert-Jan;
- Kroeze, Hans;
- Chevalley-Maurel, Severine;
- Franke-Fayard, Blandine;
- Sauerwein, Robert W.;
- Hill, Adrian V. S.;
- Dechering, Koen J.;
- Janse, Chris J.;
- Khan, Shahid M.
Publication type:
Article
A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00572-x
By:
- Baker, David A.;
- Stewart, Lindsay B.;
- Large, Jonathan M.;
- Bowyer, Paul W.;
- Ansell, Keith H.;
- Jiménez-Díaz, María B.;
- El Bakkouri, Majida;
- Birchall, Kristian;
- Dechering, Koen J.;
- Bouloc, Nathalie S.;
- Coombs, Peter J.;
- Whalley, David;
- Harding, Denise J.;
- Smiljanic-Hurley, Ela;
- Wheldon, Mary C.;
- Walker, Eloise M.;
- Dessens, Johannes T.;
- Lafuente, María José;
- Sanz, Laura M.;
- Gamo, Francisco-Javier
Publication type:
Article
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.
Published in:
2016
By:
- Le Bihan, Amélie;
- de Kanter, Ruben;
- Angulo-Barturen, Iñigo;
- Binkert, Christoph;
- Boss, Christoph;
- Brun, Reto;
- Brunner, Ralf;
- Buchmann, Stephan;
- Burrows, Jeremy;
- Dechering, Koen J.;
- Delves, Michael;
- Ewerling, Sonja;
- Ferrer, Santiago;
- Fischli, Christoph;
- Gamo–Benito, Francisco Javier;
- Gnädig, Nina F.;
- Heidmann, Bibia;
- Jiménez-Díaz, María Belén;
- Leroy, Didier;
- Martínez, Maria Santos
Publication type:
journal article
A versatile Plasmodium falciparum reporter line expressing NanoLuc enables highly sensitive multi-stage drug assays.
Published in:
Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05078-5
By:
- Miyazaki, Yukiko;
- Vos, Martijn W.;
- Geurten, Fiona J. A.;
- Bigeard, Pierre;
- Kroeze, Hans;
- Yoshioka, Shohei;
- Arisawa, Mitsuhiro;
- Inaoka, Daniel Ken;
- Soulard, Valerie;
- Dechering, Koen J.;
- Franke-Fayard, Blandine;
- Miyazaki, Shinya
Publication type:
Article
Novel pantothenate derivatives for anti-malarial chemotherapy.
Published in:
Malaria Journal, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12936-015-0673-8
By:
- Pett, Helmi E.;
- Jansen, Patrick A. M.;
- Hermkens, Pedro H. H.;
- Botman, Peter N. M.;
- Beuckens-Schortinghuis, Christien A.;
- Blaauw, Richard H.;
- Graumans, Wouter;
- van de Vegte-Bolmer, Marga;
- Koolen, Karin M. J.;
- Rutjes, Floris P. J. T.;
- Dechering, Koen J.;
- Sauerwein, Robert W.;
- Schalkwijk, Joost
Publication type:
Article
MicroRNA miR-378 promotes BMP2-induced osteogenic differentiation of mesenchymal progenitor cells.
Published in:
BMC Molecular Biology, 2014, v. 15, n. 1, p. 1, doi. 10.1186/1471-2199-15-1
By:
- Hupkes, Marlinda;
- Sotoca, Ana M.;
- Hendriks, José M.;
- van Zoelen, Everardus J.;
- Dechering, Koen J.
Publication type:
Article
Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening.
Published in:
Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04599-3
By:
- Miglianico, Marie;
- Bolscher, Judith M.;
- Vos, Martijn W.;
- Koolen, Karin J. M.;
- de Bruijni, Marloes;
- Rajagopal, Deeya S.;
- Chen, Emily;
- Kiczun, Michael;
- Gray, David;
- Campo, Brice;
- Sauerwein, Robert W.;
- Dechering, Koen J.
Publication type:
Article

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