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Cytokeratin-18 is a sensitive biomarker of alanine transaminase increase in a placebo-controlled, randomized, crossover trial of therapeutic paracetamol dosing (PATH-BP biomarker substudy).
- Published in:
- Toxicological Sciences, 2024, v. 199, n. 2, p. 203, doi. 10.1093/toxsci/kfae031
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- Publication type:
- Article
Evaluation of capillary miR-122 as a prognostic biomarker of paracetamol-induced liver toxicity.
- Published in:
- Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09327-6
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- Article
Candidate circulating microRNA biomarkers in dogs with chronic pancreatitis.
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- Journal of Veterinary Internal Medicine, 2024, v. 38, n. 2, p. 995, doi. 10.1111/jvim.17009
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- Article
No action is without its side effects: Adverse drug reactions and missed doses of antituberculosis therapy, a scoping review.
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- British Journal of Clinical Pharmacology, 2024, v. 90, n. 1, p. 313, doi. 10.1111/bcp.15908
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- Publication type:
- Article
Evaluation of capillary miR-122 as a prognostic biomarker of paracetamol-induced liver toxicity.
- Published in:
- Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09327-6
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- Publication type:
- Article
In severe alcohol‐related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL‐8 and micro‐RNAs.
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- Alimentary Pharmacology & Therapeutics, 2023, v. 58, n. 11/12, p. 1217, doi. 10.1111/apt.17733
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- Article
Small interfering RNA: Discovery, pharmacology and clinical development—An introductory review.
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- British Journal of Pharmacology, 2023, v. 180, n. 21, p. 2697, doi. 10.1111/bph.15972
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- Article
Choroidal and retinal thinning in chronic kidney disease independently associate with eGFR decline and are modifiable with treatment.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43125-1
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- Article
Fomepizole should not be used more liberally in paracetamol overdose.
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- British Journal of Clinical Pharmacology, 2023, v. 89, n. 2, p. 599, doi. 10.1111/bcp.15596
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- Publication type:
- Article
Endothelin blockade prevents the long-term cardiovascular and renal sequelae of acute kidney injury in mice.
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- Science Translational Medicine, 2022, v. 14, n. 675, p. 1, doi. 10.1126/scitranslmed.abf5074
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- Publication type:
- Article
Spotlight commentary: Navigating between financial risks and improved treatment outcomes with immune checkpoint inhibitors in cancer patients: The need for biomarker identification and dose optimization.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 5060, doi. 10.1111/bcp.15548
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- Publication type:
- Article
Investigation of a relationship between serum concentrations of microRNA-122 and alanine aminotransferase activity in hospitalised cats.
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- Journal of Feline Medicine & Surgery, 2022, v. 24, n. 8, p. e289, doi. 10.1177/1098612X221100071
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- Publication type:
- Article
Towards quantitative point of care detection using SERS lateral flow immunoassays.
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- Analytical & Bioanalytical Chemistry, 2022, v. 414, n. 16, p. 4541, doi. 10.1007/s00216-022-03933-8
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- Publication type:
- Article
Introduction to a series of Pro/Con papers in Clinical Toxicology.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 1, p. 56, doi. 10.1111/bcp.15128
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- Publication type:
- Article
Simultaneous Detection of Drug-Induced Liver Injury Protein and microRNA Biomarkers Using Dynamic Chemical Labelling on a Luminex MAGPIX System.
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- Analytica, 2021, v. 2, n. 4, p. 130, doi. 10.3390/analytica2040013
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- Article
Systems analysis of miRNA biomarkers to inform drug safety.
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- Archives of Toxicology, 2021, v. 95, n. 11, p. 3475, doi. 10.1007/s00204-021-03150-9
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- Publication type:
- Article
MicroRNA‐122 and cytokeratin‐18 have potential as a biomarkers of drug‐induced liver injury in European and African patients on treatment for mycobacterial infection.
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- British Journal of Clinical Pharmacology, 2021, v. 87, n. 8, p. 3206, doi. 10.1111/bcp.14736
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- Publication type:
- Article
A metabolomic analysis of thiol response for standard and modified N‐acetyl cysteine treatment regimens in patients with acetaminophen overdose.
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- CTS: Clinical & Translational Science, 2021, v. 14, n. 4, p. 1476, doi. 10.1111/cts.13009
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- Publication type:
- Article
Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury.
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- Science Translational Medicine, 2021, v. 13, n. 597, p. 1, doi. 10.1126/scitranslmed.aba8146
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- Publication type:
- Article
Urinary extracellular vesicles: A position paper by the Urine Task Force of the International Society for Extracellular Vesicles.
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- Journal of Extracellular Vesicles, 2021, v. 10, n. 7, p. 1, doi. 10.1002/jev2.12093
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- Article
Evaluating the Sensitivity and Specificity of Promising Circulating Biomarkers to Diagnose Liver Injury in Humans.
- Published in:
- Toxicological Sciences, 2021, v. 181, n. 1, p. 23, doi. 10.1093/toxsci/kfab003
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- Publication type:
- Article
Activated neutrophil fluorescent imaging technique for human lungs.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80083-w
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- Publication type:
- Article
Absolute measurement of the tissue origins of cell-free DNA in the healthy state and following paracetamol overdose.
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- BMC Medical Genomics, 2020, v. 13, n. 1, p. 1, doi. 10.1186/s12920-020-0705-2
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- Publication type:
- Article
Functionality of primary hepatic non-parenchymal cells in a 3D spheroid model and contribution to acetaminophen hepatotoxicity.
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- Archives of Toxicology, 2020, v. 94, n. 4, p. 1251, doi. 10.1007/s00204-020-02682-w
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- Publication type:
- Article
Reply to the 'Comment on "Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use"' by M. E. Mullins, M. C. Yarema, M. L. A. Sivilotti, M. Thompson, D. A. Algren, M. C. Beuhler and C. P. Holstege, Toxicol. Res., 2019, 8, DOI: 10.1039/C9TX00158A
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- 2019
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- Publication type:
- Letter to the Editor
Pharmacoepidemiology: Using randomised control trials and observational studies in clinical decision‐making.
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- British Journal of Clinical Pharmacology, 2019, v. 85, n. 9, p. 1907, doi. 10.1111/bcp.14024
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- Publication type:
- Article
Acetylcysteine in paracetamol poisoning: a perspective of 45 years of use.
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- Toxicology Research, 2019, v. 8, n. 4, p. 489, doi. 10.1039/c9tx00002j
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- Publication type:
- Article
Characterization of Triptolide-Induced Hepatotoxicity by Imaging and Transcriptomics in a Novel Zebrafish Model.
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- Toxicological Sciences, 2017, v. 159, n. 2, p. 380, doi. 10.1093/toxsci/kfx144
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- Publication type:
- Article
MicroRNA-122 can be measured in capillary blood which facilitates point-of-care testing for drug-induced liver injury.
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- British Journal of Clinical Pharmacology, 2017, v. 83, n. 9, p. 2027, doi. 10.1111/bcp.13282
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- Article
Polymerase-free measurement of microRNA-122 with single base specificity using single molecule arrays: Detection of drug-induced liver injury.
- Published in:
- PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0179669
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- Article
Resolution of Hypoglycemia and Cardiovascular Dysfunction After Rituximab Treatment of Insulin Autoimmune Syndrome.
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- 2017
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- Publication type:
- Case Study
Should we treat very large paracetamol overdose differently?
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 6, p. 1163, doi. 10.1111/bcp.13279
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- Publication type:
- Article
Resolution of Hypoglycemia and Cardiovascular Dysfunction After Rituximab Treatment of Insulin Autoimmune Syndrome.
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- 2017
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- Publication type:
- letter
The effect of renal dysfunction and haemodialysis on circulating liver specific miR-122.
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- British Journal of Clinical Pharmacology, 2017, v. 83, n. 3, p. 584, doi. 10.1111/bcp.13136
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- Article
A qualitative study of the relationship between the Scottish Medicines Consortium and their clinical experts.
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- Journal of Evaluation in Clinical Practice, 2016, v. 22, n. 3, p. 311, doi. 10.1111/jep.12325
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- Article
Disproportionate effect on child admissions of the change in Medicines and Healthcare Products Regulatory Agency guidance for management of paracetamol poisoning: an analysis of hospital admissions for paracetamol overdose in England and Scotland.
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- British Journal of Clinical Pharmacology, 2015, v. 80, n. 6, p. 1458, doi. 10.1111/bcp.12779
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- Article
Target biomarker profile for the clinical management of paracetamol overdose.
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- British Journal of Clinical Pharmacology, 2015, v. 80, n. 3, p. 351, doi. 10.1111/bcp.12699
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- Publication type:
- Article
Zebrafish as model organisms for studying drug-induced liver injury.
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- British Journal of Clinical Pharmacology, 2014, v. 78, n. 6, p. 1217, doi. 10.1111/bcp.12408
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- Publication type:
- Article
Effect of the UK's revised paracetamol poisoning management guidelines on admissions, adverse reactions and costs of treatment.
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- British Journal of Clinical Pharmacology, 2014, v. 78, n. 3, p. 610, doi. 10.1111/bcp.12362
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- Publication type:
- Article
Early detection of paracetamol toxicity using circulating liver microRNA and markers of cell necrosis.
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- British Journal of Clinical Pharmacology, 2014, v. 77, n. 5, p. 904, doi. 10.1111/bcp.12214
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- Publication type:
- Article
Quantification of human urinary exosomes by nanoparticle tracking analysis.
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- Journal of Physiology, 2013, v. 591, n. 23, p. 5833, doi. 10.1113/jphysiol.2013.264069
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- Publication type:
- Article
Measurement of renal function in patients with chronic kidney disease.
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- British Journal of Clinical Pharmacology, 2013, v. 76, p. 504, doi. 10.1111/bcp.12198
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- Publication type:
- Article
Measurement of renal function in patients with chronic kidney disease.
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- British Journal of Clinical Pharmacology, 2013, v. 76, n. 4, p. 504, doi. 10.1111/bcp.12198
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- Publication type:
- Article
Urinary exosomes: A reservoir for biomarker discovery and potential mediators of intrarenal signalling.
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- Proteomics, 2013, v. 13, n. 10/11, p. 1572, doi. 10.1002/pmic.201200285
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- Publication type:
- Article
A systematic review of the effect of paracetamol on blood pressure in hypertensive and non-hypertensive subjects.
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- British Journal of Clinical Pharmacology, 2013, v. 75, n. 6, p. 1396, doi. 10.1111/bcp.12032
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- Publication type:
- Article
Scottish and Newcastle Antiemetic Pre-treatment for paracetamol poisoning study (SNAP).
- Published in:
- BMC Pharmacology & Toxicology, 2013, v. 14, p. 1, doi. 10.1186/2050-6511-14-20
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- Publication type:
- Article
Measuring urinary tubular biomarkers in type 2 diabetes does not add prognostic value beyond established risk factors.
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- Kidney International, 2012, v. 82, n. 7, p. 812, doi. 10.1038/ki.2012.218
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- Publication type:
- Article
Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells.
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- Journal of Physiology, 2011, v. 589, n. 24, p. 6119, doi. 10.1113/jphysiol.2011.220277
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- Publication type:
- Article
The application of mass-spectrometry-based protein biomarker discovery to theragnostics.
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- British Journal of Clinical Pharmacology, 2010, v. 69, n. 4, p. 367, doi. 10.1111/j.1365-2125.2009.03610.x
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- Publication type:
- Article
Disease mongering – a challenge for everyone involved in healthcare.
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- British Journal of Clinical Pharmacology, 2007, v. 64, n. 2, p. 122, doi. 10.1111/j.1365-2125.2006.02830.x
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- Publication type:
- Article