Works matching AU Deane, Charlotte M

Results: 164

Rapid discovery of monoclonal antibodies by microfluidics-enabled FACS of single pathogen-specific antibody-secreting cells.

Published in:

Nature Biotechnology, 2025, v. 43, n. 6, p. 960, doi. 10.1038/s41587-024-02346-5

By:

Fischer, Katrin;
Lulla, Aleksei;
So, Tsz Y.;
Pereyra-Gerber, Pehuén;
Raybould, Matthew I. J.;
Kohler, Timo N.;
Yam-Puc, Juan Carlos;
Kaminski, Tomasz S.;
Hughes, Robert;
Pyeatt, Gwendolyn L.;
Leiss-Maier, Florian;
Brear, Paul;
Matheson, Nicholas J.;
Deane, Charlotte M.;
Hyvönen, Marko;
Thaventhiran, James E. D.;
Hollfelder, Florian

Publication type:

Article

In silico structural modeling of multiple epigenetic marks on DNA.

Published in:

Bioinformatics, 2018, v. 34, n. 1, p. 41, doi. 10.1093/bioinformatics/btx516

By:

Krawczyk, Konrad;
Demharter, Samuel;
Knapp, Bernhard;
Deane, Charlotte M;
Minary, Peter

Publication type:

Article

Sphinx: merging knowledge-based and ab initio approaches to improve protein loop prediction.

Published in:

Bioinformatics, 2017, v. 33, n. 9, p. 1346, doi. 10.1093/bioinformatics/btw823

By:

Marks, Claire;
Nowak, Jaroslaw;
Klostermann, Stefan;
Georges, Guy;
Dunbar, James;
Jiye Shi;
Kelm, Sebastian;
Deane, Charlotte M.

Publication type:

Article

Comparing co-evolution methods and their application to template-free protein structure prediction.

Published in:

Bioinformatics, 2017, v. 33, n. 3, p. 373, doi. 10.1093/bioinformatics/btw618

By:

de Oliveira, Saulo Henrique Pires;
Jiye Shi;
Deane, Charlotte M.

Publication type:

Article

ANARCI: antigen receptor numbering and receptor classification.

Published in:

Bioinformatics, 2016, v. 32, n. 2, p. 298, doi. 10.1093/bioinformatics/btv552

By:

Dunbar, James;
Deane, Charlotte M.

Publication type:

Article

Exploring peptide/MHC detachment processes using hierarchical natural move Monte Carlo.

Published in:

Bioinformatics, 2016, v. 32, n. 2, p. 181, doi. 10.1093/bioinformatics/btv502

By:

Knapp, Bernhard;
Demharter, Samuel;
Deane, Charlotte M.;
Minary, Peter

Publication type:

Article

Alignment-free protein interaction network comparison.

Published in:

Bioinformatics, 2014, v. 30, n. 17, p. i430, doi. 10.1093/bioinformatics/btu447

By:

Ali, Waqar;
Rito, Tiago;
Reinert, Gesine;
Sun, Fengzhu;
Deane, Charlotte M.

Publication type:

Article

Improving B-cell epitope prediction and its application to global antibody-antigen docking.

Published in:

Bioinformatics, 2014, v. 30, n. 16, p. 2288, doi. 10.1093/bioinformatics/btu190

By:

Krawczyk, Konrad;
Liu, Xiaofeng;
Baker, Terry;
Shi, Jiye;
Deane, Charlotte M.

Publication type:

Article

MP-T: improving membrane protein alignment for structure prediction.

Published in:

Bioinformatics, 2013, v. 29, n. 1, p. 54, doi. 10.1093/bioinformatics/bts640

By:

Hill, Jamie R.;
Deane, Charlotte M.

Publication type:

Article

Environment specific substitution tables improve membrane protein alignment.

Published in:

Bioinformatics, 2011, v. 27, n. 13, p. i15, doi. 10.1093/bioinformatics/btr230

By:

Hill, Jamie R.;
Kelm, Sebastian;
Shi, Jiye;
Deane, Charlotte M.

Publication type:

Article

MEDELLER: homology-based coordinate generation for membrane proteins.

Published in:

Bioinformatics, 2010, v. 26, n. 22, p. 2833, doi. 10.1093/bioinformatics/btq554

By:

Kelm, Sebastian;
Jiye Shi;
Deane, Charlotte M.

Publication type:

Article

How threshold behaviour affects the use of subgraphs for network comparison.

Published in:

Bioinformatics, 2010, v. 26, n. 18, p. i611, doi. 10.1093/bioinformatics/btq386

By:

Rito, Tiago;
Zi Wang;
Deane, Charlotte M.;
Reinert, Gesine

Publication type:

Article

Exploring the potential of template-based modelling.

Published in:

Bioinformatics, 2010, v. 26, n. 15, p. 1849, doi. 10.1093/bioinformatics/btq294

By:

Lance, Braddon K.;
Deane, Charlotte M.;
Wood, Graham R.

Publication type:

Article

Functionally guided alignment of protein interaction networks for module detection.

Published in:

Bioinformatics, 2009, v. 25, n. 23, p. 3166, doi. 10.1093/bioinformatics/btp569

By:

Ali, Waqar;
Deane, Charlotte M.

Publication type:

Article

iMembrane: homology-based membrane-insertion of proteins.

Published in:

Bioinformatics, 2009, v. 25, n. 8, p. 1086, doi. 10.1093/bioinformatics/btp102

By:

Sebastian Kelm;
Jiye Shi;
Charlotte M. Deane

Publication type:

Article

A statistical approach using network structure in the prediction of protein characteristics.

Published in:

Bioinformatics, 2007, v. 23, n. 17, p. 2314, doi. 10.1093/bioinformatics/btm342

By:

Pao-Yang Chen;
Charlotte M. Deane;
Gesine Reinert

Publication type:

Article

Cotranslational protein folding fact or fiction?

Published in:

Bioinformatics, 2007, v. 23, n. 13, p. i142, doi. 10.1093/bioinformatics/btm175

By:

Charlotte M. Deane;
Mingqiang Dong;
Fabien P.E. Huard;
Braddon K. Lance;
Graham R. Wood

Publication type:

Article

Empirical Bayes functional models for hydrogen deuterium exchange mass spectrometry.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03517-3

By:

Crook, Oliver M.;
Chung, Chun-wa;
Deane, Charlotte M.

Publication type:

Article

Ranking of communities in multiplex spatiotemporal models of brain dynamics.

Published in:

Applied Network Science, 2022, v. 7, n. 1, p. 1, doi. 10.1007/s41109-022-00454-2

By:

Wilsenach, James B.;
Warnaby, Catherine E.;
Deane, Charlotte M.;
Reinert, Gesine D.

Publication type:

Article

Comparative Analysis of the CDR Loops of Antigen Receptors.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02454

By:

Wong, Wing Ki;
Leem, Jinwoo;
Deane, Charlotte M.

Publication type:

Article

Epitope profiling using computational structural modelling demonstrated on coronavirus-binding antibodies.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 12, p. 1, doi. 10.1371/journal.pcbi.1009675

By:

Robinson, Sarah A.;
Raybould, Matthew I. J.;
Schneider, Constantin;
Wong, Wing Ki;
Marks, Claire;
Deane, Charlotte M.

Publication type:

Article

Public Baseline and shared response structures support the theory of antibody repertoire functional commonality.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 3, p. 1, doi. 10.1371/journal.pcbi.1008781

By:

Raybould, Matthew I. J.;
Marks, Claire;
Kovaltsuk, Aleksandr;
Lewis, Alan P.;
Shi, Jiye;
Deane, Charlotte M.

Publication type:

Article

How old is your fold?

Published in:

Bioinformatics, 2005, v. 21, p. i449, doi. 10.1093/bioinformatics/bti1008

By:

Winstanley, Henry F.;
Abeln, Sanne;
Deane, Charlotte M.

Publication type:

Article

How old is your fold?

Published in:

Bioinformatics, 2005, v. 21, n. 1, p. i449

By:

Charlotte M. Deane

Publication type:

Article

SCORE: predicting the core of protein models.

Published in:

Bioinformatics, 2001, v. 17, n. 6, p. 541, doi. 10.1093/bioinformatics/17.6.541

By:

Deane, Charlotte M.;
Kaas, Quentin;
Blundell, Tom L.

Publication type:

Article

Browsing the SLoop database of structurally classified loops connecting elements of protein secondary structure.

Published in:

Bioinformatics, 2000, v. 16, n. 6, p. 513, doi. 10.1093/bioinformatics/16.6.513

By:

Burke, David F.;
Deane, Charlotte M.;
Blundell, Tom L.

Publication type:

Article

WONKA and OOMMPPAA: analysis of protein-ligand interaction data to direct structure-based drug design.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2017, v. 73, n. 3, p. 279, doi. 10.1107/S2059798316009529

By:

Deane, Charlotte M.;
Wall, Ian D.;
Green, Darren V. S.;
Marsden, Brian D.;
Bradley, Anthony R.

Publication type:

Article

Different B cell subpopulations show distinct patterns in their IgH repertoire metrics.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.73111

By:

Ghraichy, Marie;
von Niederhäusern, Valentin;
Kovaltsuk, Aleksandr;
Galson, Jacob D.;
Deane, Charlotte M.;
Trück, Johannes

Publication type:

Article

The allosteric modulation of complement C5 by knob domain peptides.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.63586

By:

Macpherson, Alex;
Laabei, Maisem;
Ahdash, Zainab;
Graewert, Melissa A.;
Birtley, James R.;
Schulze, Monika-Sarah E. D.;
Crennell, Susan;
Robinson, Sarah A.;
Holmes, Ben;
Oleinikovas, Vladas;
Nilsson, Per H.;
Snowden, James;
Ellis, Victoria;
Mollnes, Tom Eirik;
Deane, Charlotte M.;
Svergun, Dmitri;
Lawson, Alastair D. G.;
van den Elsen, Jean M. H.

Publication type:

Article

Computational mining of B cell receptor repertoires reveals antigen-specific and convergent responses to Ebola vaccination.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1383753

By:

Richardson, Eve;
Bibi, Sagida;
McLean, Florence;
Schimanski, Lisa;
Rijal, Pramila;
Ghraichy, Marie;
von Niederhäusern, Valentin;
Trück, Johannes;
Clutterbuck, Elizabeth A.;
O'Connor, Daniel;
Luhn, Kerstin;
Townsend, Alain;
Peters, Bjoern;
Pollard, Andrew J.;
Deane, Charlotte M.;
Kelly, Dominic F.

Publication type:

Article

Prospects for the computational humanization of antibodies and nanobodies.

Published in:

Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1399438

By:

Gordon, Gemma L.;
Raybould, Matthew I. J.;
Wong, Ashley;
Deane, Charlotte M.

Publication type:

Article

Investigating the ability of deep learning-based structure prediction to extrapolate and/or enrich the set of antibody CDR canonical forms.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1352703

By:

Greenshields-Watson, Alexander;
Abanades, Brennan;
Deane, Charlotte M.

Publication type:

Article

The functional domain grouping of microtubule associated proteins.

Published in:

Communicative & Integrative Biology, 2008, v. 1, n. 1, p. 47, doi. 10.4161/cib.1.1.6795

By:

Fisher, Katherine H.;
Deane, Charlotte M.;
Wakefield, James G.

Publication type:

Article

Building a Better Fragment Library for De Novo Protein Structure Prediction.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123998

By:

de Oliveira, Saulo H. P.;
Shi, Jiye;
Deane, Charlotte M.

Publication type:

Article

Local Network Patterns in Protein-Protein Interfaces.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0057031

By:

Luo, Qiang;
Hamer, Rebecca;
Reinert, Gesine;
Deane, Charlotte M.

Publication type:

Article

Predicting Inter-Species Cross-Talk in Two-Component Signalling Systems.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037737

By:

Pawelczyk, Sonja;
Scott, Kathryn A.;
Hamer, Rebecca;
Blades, Gareth;
Deane, Charlotte M.;
Wadhams, George H.

Publication type:

Article

A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility.

Published in:

Human Reproduction, 2012, v. 27, n. 1, p. 222, doi. 10.1093/humrep/der384

By:

Kashir, Junaid;
Konstantinidis, Michalis;
Jones, Celine;
Lemmon, Bernadette;
Chang Lee, Hoi;
Hamer, Rebecca;
Heindryckx, Bjorn;
Deane, Charlotte M.;
De Sutter, Petra;
Fissore, Rafael A.;
Parrington, John;
Wells, Dagan;
Coward, Kevin

Publication type:

Article

Narrowing the gap between machine learning scoring functions and free energy perturbation using augmented data.

Published in:

Communications Chemistry, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42004-025-01428-y

By:

Valsson, Ísak;
Warren, Matthew T.;
Deane, Charlotte M.;
Magarkar, Aniket;
Morris, Garrett M.;
Biggin, Philip C.

Publication type:

Article

KA-Search, a method for rapid and exhaustive sequence identity search of known antibodies.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38108-7

By:

Olsen, Tobias H.;
Abanades, Brennan;
Moal, Iain H.;
Deane, Charlotte M.

Publication type:

Article

Structurally Mapping Antibody Repertoires.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01698

By:

Krawczyk, Konrad;
Kelm, Sebastian;
Kovaltsuk, Aleksandr;
Galson, Jacob D.;
Kelly, Dominic;
Trück, Johannes;
Regep, Cristian;
Leem, Jinwoo;
Wong, Wing K.;
Nowak, Jaroslaw;
Snowden, James;
Wright, Michael;
Starkie, Laura;
Scott-Tucker, Anthony;
Shi, Jiye;
Deane, Charlotte M.

Publication type:

Article

How B-Cell Receptor Repertoire Sequencing Can Be Enriched with Structural Antibody Data.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01753

By:

Kovaltsuk, Aleksandr;
Krawczyk, Konrad;
Galson, Jacob D.;
Kelly, Dominic F.;
Deane, Charlotte M.;
Trück, Johannes

Publication type:

Article

Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains.

Published in:

2024

By:

Chinery, Lewis;
Jeliazkov, Jeliazko R.;
Deane, Charlotte M.

Publication type:

Report

A comparative study of the developability of full-length antibodies, fragments, and bispecific formats reveals higher stability risks for engineered constructs.

Published in:

2024

By:

Condado-Morales, Itzel;
Dingfelder, Fabian;
Waibel, Isabel;
Turnbull, Oliver M.;
Patel, Bhargav;
Cao, Zheng;
Rose Bjelke, Jais;
Nedergaard Grell, Susanne;
Bennet, Anja;
Hummer, Alissa M.;
Raybould, Matthew I. J.;
Deane, Charlotte M.;
Egebjerg, Thomas;
Lorenzen, Nikolai;
Arosio, Paolo

Publication type:

Report

Challenges in antibody structure prediction.

Published in:

mAbs (1942-0862), 2023, v. 15, n. 1, p. 1, doi. 10.1080/19420862.2023.2175319

By:

Fernández-Quintero, Monica L.;
Kokot, Janik;
Waibl, Franz;
Fischer, Anna-Lena M.;
Quoika, Patrick K.;
Deane, Charlotte M.;
Liedl, Klaus R.

Publication type:

Article

Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics.

Published in:

mAbs (1942-0862), 2022, v. 14, n. 1, p. 1, doi. 10.1080/19420862.2021.2020082

By:

Khetan, Rahul;
Curtis, Robin;
Deane, Charlotte M.;
Hadsund, Johannes Thorling;
Kar, Uddipan;
Krawczyk, Konrad;
Kuroda, Daisuke;
Robinson, Sarah A.;
Sormanni, Pietro;
Tsumoto, Kouhei;
Warwicker, Jim;
Martin, Andrew C.R.

Publication type:

Article

Current strategies for detecting functional convergence across B-cell receptor repertoires.

Published in:

mAbs (1942-0862), 2021, v. 13, n. 1, p. 1, doi. 10.1080/19420862.2021.1996732

By:

Raybould, Matthew I. J.;
Rees, Anthony R.;
Deane, Charlotte M.

Publication type:

Article

Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope.

Published in:

2021

By:

Wong, Wing Ki;
Robinson, Sarah A.;
Bujotzek, Alexander;
Georges, Guy;
Lewis, Alan P.;
Shi, Jiye;
Snowden, James;
Taddese, Bruck;
Deane, Charlotte M.

Publication type:

Report

A computational method for immune repertoire mining that identifies novel binders from different clonotypes, demonstrated by identifying anti-pertussis toxoid antibodies.

Published in:

2021

By:

Richardson, Eve;
Galson, Jacob D.;
Kellam, Paul;
Kelly, Dominic F.;
Smith, Sarah E.;
Palser, Anne;
Watson, Simon;
Deane, Charlotte M.

Publication type:

Report

Looking for therapeutic antibodies in next-generation sequencing repositories.

Published in:

2019

By:

Krawczyk, Konrad;
Raybould, Matthew I. J.;
Kovaltsuk, Aleksandr;
Deane, Charlotte M.

Publication type:

Report

Developability of Biotherapeutics: Computational Approaches . Edited by Sandeep Kumar and Satish K. Singh.

Published in:

2017

By:

Deane, Charlotte M.;
Vásquez, Maximiliano

Publication type:

Book Review