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Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28839-y
By:
- Lee, Miyoung;
- Hamilton, Jamie A. G.;
- Talekar, Ganesh R.;
- Ross, Anthony J.;
- Michael, Langston;
- Rupji, Manali;
- Dwivedi, Bhakti;
- Raikar, Sunil S.;
- Boss, Jeremy;
- Scharer, Christopher D.;
- Graham, Douglas K.;
- DeRyckere, Deborah;
- Porter, Christopher C.;
- Henry, Curtis J.
Publication type:
Article
MerTK inhibition in tumor leukocytes decreases tumor growth and metastasis.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 8, p. 3231, doi. 10.1172/JCI67655
By:
- Cook, Rebecca S.;
- Jacobsen, Kristen M.;
- Wofford, Anne M.;
- DeRyckere, Deborah;
- Stanford, Jamie;
- Prieto, Anne L.;
- Redente, Elizabeth;
- Sandahl, Melissa;
- Hunter, Debra M.;
- Strunk, Karen E.;
- Graham, Douglas K.;
- Earp III, H. Shelton
Publication type:
Article
MERTK receptor tyrosine kinase is a therapeutic target in melanoma.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 5, p. 2257, doi. 10.1172/JCI67816
By:
- Schlegel, Jennifer;
- Sambade, Maria J.;
- Sather, Susan;
- Moschos, Stergios J.;
- Aik-Choon Tan;
- Winges, Amanda;
- DeRyckere, Deborah;
- Carson, Craig C.;
- Trembath, Dimitri G.;
- Tentler, John J.;
- Eckhardt, S. Gail;
- Pei-Fen Kuan;
- Hamilton, Ronald L.;
- Duncan, Lyn M.;
- Miller, C. Ryan;
- Nikolaishvili-Feinberg, Nana;
- Midkiff, Bentley R.;
- Jing Liu;
- Weihe Zhang;
- Chao Yang
Publication type:
Article
The role of nucleotide binding and hydrolysis in the function of the fission yeast cdc18+ gene...
Published in:
Genetics, 1999, v. 151, n. 4, p. 1445, doi. 10.1093/genetics/151.4.1445
By:
- DeRyckere, Deborah;
- Smith, Cheryl L.
Publication type:
Article
Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28839-y
By:
- Lee, Miyoung;
- Hamilton, Jamie A. G.;
- Talekar, Ganesh R.;
- Ross, Anthony J.;
- Michael, Langston;
- Rupji, Manali;
- Dwivedi, Bhakti;
- Raikar, Sunil S.;
- Boss, Jeremy;
- Scharer, Christopher D.;
- Graham, Douglas K.;
- DeRyckere, Deborah;
- Porter, Christopher C.;
- Henry, Curtis J.
Publication type:
Article
Constitutively Synergistic Multiagent Drug Formulations Targeting MERTK, FLT3, and BCL-2 for Treatment of AML.
Published in:
Pharmaceutical Research, 2023, v. 40, n. 9, p. 2133, doi. 10.1007/s11095-023-03596-9
By:
- Kelvin, James M.;
- Jain, Juhi;
- Thapa, Aashis;
- Qui, Min;
- Birnbaum, Lacey A.;
- Moore, Samuel G.;
- Zecca, Henry;
- Summers, Ryan J.;
- Switchenko, Jeffrey M.;
- Costanza, Emma;
- Uricoli, Biaggio;
- Wang, Xiaodong;
- Jui, Nathan T.;
- Fu, Haian;
- Du, Yuhong;
- DeRyckere, Deborah;
- Graham, Douglas K.;
- Dreaden, Erik C.
Publication type:
Article
Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41994-0
By:
- Mumme, Hope;
- Thomas, Beena E.;
- Bhasin, Swati S.;
- Krishnan, Upaasana;
- Dwivedi, Bhakti;
- Perumalla, Pruthvi;
- Sarkar, Debasree;
- Ulukaya, Gulay B.;
- Sabnis, Himalee S.;
- Park, Sunita I.;
- DeRyckere, Deborah;
- Raikar, Sunil S.;
- Pauly, Melinda;
- Summers, Ryan J.;
- Castellino, Sharon M.;
- Wechsler, Daniel S.;
- Porter, Christopher C.;
- Graham, Douglas K.;
- Bhasin, Manoj
Publication type:
Article
Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia.
Published in:
Genome Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13073-023-01241-z
By:
- Mumme, Hope L.;
- Raikar, Sunil S.;
- Bhasin, Swati S.;
- Thomas, Beena E.;
- Lawrence, Taylor;
- Weinzierl, Elizabeth P.;
- Pang, Yakun;
- DeRyckere, Deborah;
- Gawad, Chuck;
- Wechsler, Daniel S.;
- Porter, Christopher C.;
- Castellino, Sharon M.;
- Graham, Douglas K.;
- Bhasin, Manoj
Publication type:
Article
Prolonged Exposure to a Mer Ligand in Leukemia: Gas6 Favors Expression of a Partial Mer Glycoform and Reveals a Novel Role for Mer in the Nucleus.
Published in:
PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031635
By:
- Migdall-Wilson, Justine;
- Bates, Christine;
- Schlegel, Jennifer;
- Brandão, Luis;
- Linger, Rachel M. A.;
- DeRyckere, Deborah;
- Graham, Douglas K.
Publication type:
Article
MERTK Is a Potential Therapeutic Target in Ewing Sarcoma.
Published in:
Cancers, 2024, v. 16, n. 16, p. 2831, doi. 10.3390/cancers16162831
By:
- Smart, Sherri K.;
- Yeung, Tsz Y.;
- Santos, M. Olivia;
- McSwain, Leon F.;
- Wang, Xiaodong;
- Frye, Stephen V.;
- Earp III, H. Shelton;
- DeRyckere, Deborah;
- Graham, Douglas K.
Publication type:
Article
Therapeutic Targeting of MERTK and BCL-2 in T-Cell and Early T-Precursor Acute Lymphoblastic Leukemia.
Published in:
Cancers, 2022, v. 14, n. 24, p. 6142, doi. 10.3390/cancers14246142
By:
- Summers, Ryan J.;
- Jain, Juhi;
- Vasileiadi, Eleana;
- Smith, Brittany;
- Chimenti, Madison L.;
- Yeung, Tsz Y.;
- Kelvin, James;
- Wang, Xiaodong;
- Frye, Stephen V.;
- Earp, H. Shelton;
- Tyner, Jeffrey W.;
- Dreaden, Erik C.;
- DeRyckere, Deborah;
- Graham, Douglas K.
Publication type:
Article
Targeting MERTK and AXL in EGFR Mutant Non-Small Cell Lung Cancer.
Published in:
Cancers, 2021, v. 13, n. 22, p. 5639, doi. 10.3390/cancers13225639
By:
- Yan, Dan;
- Earp, H. Shelton;
- DeRyckere, Deborah;
- Graham, Douglas K.
Publication type:
Article
The Emerging Role of TYRO3 as a Therapeutic Target in Cancer.
Published in:
Cancers, 2018, v. 10, n. 12, p. 474, doi. 10.3390/cancers10120474
By:
- Smart, Sherri K.;
- Vasileiadi, Eleana;
- Wang, Xiaodong;
- DeRyckere, Deborah;
- Graham, Douglas K.
Publication type:
Article
Targeting the TAM Receptors in Leukemia.
Published in:
Cancers, 2016, v. 8, n. 11, p. 101, doi. 10.3390/cancers8110101
By:
- Huey, Madeline G.;
- Minson, Katherine A.;
- Shelton Earp, H.;
- DeRyckere, Deborah;
- Graham, Douglas K.
Publication type:
Article
Vandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents.
Published in:
Investigational New Drugs, 2012, v. 30, n. 2, p. 468, doi. 10.1007/s10637-010-9572-6
By:
- Macy, Margaret;
- DeRyckere, Deborah;
- Gore, Lia
Publication type:
Article
MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0165107
By:
- Sufit, Alexandra;
- Lee-Sherick, Alisa B.;
- DeRyckere, Deborah;
- Rupji, Manali;
- Dwivedi, Bhakti;
- Varella-Garcia, Marileila;
- Pierce, Angela M.;
- Kowalski, Jeanne;
- Wang, Xiaodong;
- Frye, Stephen V.;
- Earp, H. Shelton;
- Keating, Amy K.;
- Graham, Douglas K.
Publication type:
Article
Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission.
Published in:
Journal of Hematology & Oncology, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8722-6-10
By:
- Christoph, Sandra;
- Schlegel, Jennifer;
- Alvarez-Calderon, Francesca;
- Yong-Mi Kim;
- Brandao, Luis N.;
- DeRyckere, Deborah;
- Graham, Douglas K.
Publication type:
Article
Machine learning classifier approaches for predicting response to RTK-type-III inhibitors demonstrate high accuracy using transcriptomic signatures and ex vivo data.
Published in:
Bioinformatics Advances, 2023, v. 3, n. 1, p. 1, doi. 10.1093/bioadv/vbad034
By:
- Ferrato, Mauricio H;
- Marsh, Adam G;
- Franke, Karl R;
- Huang, Benjamin J;
- Kolb, E Anders;
- DeRyckere, Deborah;
- Grahm, Douglas K;
- Chandrasekaran, Sunita;
- Crowgey, Erin L
Publication type:
Article
Discovery of Macrocyclic Pyrimidines as MerTK-Specific Inhibitors.
Published in:
ChemMedChem, 2017, v. 12, n. 3, p. 207, doi. 10.1002/cmdc.201600589
By:
- McIver, Andrew L.;
- Zhang, Weihe;
- Liu, Qingyang;
- Jiang, Xinpeng;
- Stashko, Michael A.;
- Nichols, James;
- Miley, Michael J.;
- Norris‐Drouin, Jacqueline;
- Machius, Mischa;
- DeRyckere, Deborah;
- Wood, Edgar;
- Graham, Douglas K.;
- Earp, H. Shelton;
- Kireev, Dmitri;
- Frye, Stephen V.;
- Wang, Xiaodong
Publication type:
Article
Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening.
Published in:
Advanced Materials, 2022, v. 34, n. 10, p. 1, doi. 10.1002/adma.202108084
By:
- O'Melia, Meghan J.;
- Mulero‐Russe, Adriana;
- Kim, Jihoon;
- Pybus, Alyssa;
- DeRyckere, Deborah;
- Wood, Levi;
- Graham, Douglas K.;
- Botchwey, Edward;
- García, Andrés J.;
- Thomas, Susan N.
Publication type:
Article
Synthetic Matrix Scaffolds Engineer the In Vivo Tumor Immune Microenvironment for Immunotherapy Screening.
Published in:
Advanced Materials, 2022, v. 34, n. 10, p. 1, doi. 10.1002/adma.202108084
By:
- O'Melia, Meghan J.;
- Mulero‐Russe, Adriana;
- Kim, Jihoon;
- Pybus, Alyssa;
- DeRyckere, Deborah;
- Wood, Levi;
- Graham, Douglas K.;
- Botchwey, Edward;
- García, Andrés J.;
- Thomas, Susan N.
Publication type:
Article
The TAM family: phosphatidylserine-sensing receptor tyrosine kinases gone awry in cancer.
Published in:
Nature Reviews Cancer, 2014, v. 14, n. 12, p. 769, doi. 10.1038/nrc3847
By:
- Graham, Douglas K.;
- DeRyckere, Deborah;
- Davies, Kurtis D.;
- Earp, H. Shelton
Publication type:
Article
The TAM family: phosphatidylserine sensing receptor tyrosine kinases gone awry in cancer.
Published in:
2014
By:
- Graham, Douglas K;
- DeRyckere, Deborah;
- Davies, Kurtis D;
- Earp, H Shelton
Publication type:
journal article
Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39152-z
By:
- Bhasin, Swati S.;
- Thomas, Beena E.;
- Summers, Ryan J.;
- Sarkar, Debasree;
- Mumme, Hope;
- Pilcher, William;
- Emam, Mohamed;
- Raikar, Sunil S.;
- Park, Sunita I.;
- Castellino, Sharon M.;
- Graham, Douglas K.;
- Bhasin, Manoj K.;
- DeRyckere, Deborah
Publication type:
Article

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