Works by DeLeo, Frank R.

Results: 67

Waves of resistance: Staphylococcus aureus in the antibiotic era.

Published in:

Nature Reviews Microbiology, 2009, v. 7, n. 9, p. 629, doi. 10.1038/nrmicro2200

By:

Chambers, Henry F.;
DeLeo, Frank R.

Publication type:

Article

Carbapenem-Resistant, Virulence Plasmid--Harboring Klebsiella pneumoniae, United States.

Published in:

Emerging Infectious Diseases, 2025, v. 31, n. 4, p. 761, doi. 10.3201/eid3104.241396

By:

Jianping Jiang;
Tengfei Long;
Porter, Adeline R.;
Lovey, Arianne;
Lee, Annie;
Jacob, Jesse Thomas;
Arias, Cesar A.;
Bonomo, Robert;
Kalayjian, Robert;
Yanan Zhao;
DeLeo, Frank R.;
van Duin, David;
Kreiswirth, Barry N.;
Liang Chen

Publication type:

Article

Seasonal H3N2 influenza A virus fails to enhance Staphylococcus aureus co-infection in a non-human primate respiratory tract infection model.

Published in:

Virulence, 2013, v. 4, n. 8, p. 707, doi. 10.4161/viru.26572

By:

Kobayashi, Scott D;
Olsen, Randall J;
LaCasse, Rachel A;
Safronetz, David;
Ashraf, Madiha;
Porter, Adeline R;
Braughton, Kevin R;
Feldmann, Friederike;
Clifton, Dawn R;
Kash, John C;
Bailey, John R;
Gardner, Donald J;
Otto, Michael;
Brining, Douglas L;
Kreiswirth, Barry N;
Taubenberger, Jeffrey K;
Parnell, Michael J;
Feldmann, Heinz;
Musser, James M;
DeLeo, Frank R

Publication type:

Article

A MRSA-terious enemy among us: Boosting MRSA vaccines.

Published in:

Nature Medicine, 2011, v. 17, n. 2, p. 168, doi. 10.1038/nm0211-168

By:

Kobayashi, Scott D.;
DeLeo, Frank R.

Publication type:

Article

Poring over pores: α-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia.

Published in:

2007

By:

Wardenburg, Juliane Bubeck;
Taeok Bae;
Otto, Michael;
DeLeo, Frank R.;
Schneewind, Olaf

Publication type:

Letter

Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA.

Published in:

Nature Medicine, 2007, v. 13, n. 12, p. 1510, doi. 10.1038/nm1656

By:

Rong Wang;
Braughton, Kevin R.;
Kretschmer, Dorothee;
Bach, Thanh-Huy L.;
Queck, Shu Y.;
Min Li;
Kennedy, Adam D.;
Dorward, David W.;
Klebanoff, Seymour J.;
Peschel, Andreas;
DeLeo, Frank R.;
Otto, Michael

Publication type:

Article

A plague upon the phagocytes.

Published in:

Nature Medicine, 2005, v. 11, n. 9, p. 927, doi. 10.1038/nm0905-927

By:

DeLeo, Frank R.;
Hinnebusch, B Joseph

Publication type:

Article

Reply to “Streptococcus pyogenes and phagocytic killing”.

Published in:

Nature Medicine, 2002, v. 8, n. 10, p. 1045, doi. 10.1038/nm1002-1045

By:

Lei, Benfang;
DeLeo, Frank R.;
Musser, James M.

Publication type:

Article

Evasion of human innate and acquired immunity by a bacterial homolog of CD11b that inhibits opsonophagocytosis.

Published in:

Nature Medicine, 2001, v. 7, n. 12, p. 1298, doi. 10.1038/nm1201-1298

By:

Lei, Benfang;
DeLeo, Frank R.;
Hoe, Nancy P.;
Graham, Morag R.;
Mackie, Stacy M.;
Cole, Robert L.;
Liu, Mengyao;
Hill, Harry R.;
Low, Donald E.;
Federle, Michael J.;
Scott, June R.;
Musser, James M.

Publication type:

Article

Selective Chemical Inhibition of <i>agr</i> Quorum Sensing in <i>Staphylococcus aureus</i> Promotes Host Defense with Minimal Impact on Resistance.

Published in:

PLoS Pathogens, 2014, v. 10, n. 6, p. 1, doi. 10.1371/journal.ppat.1004174

By:

Sully, Erin K.;
Malachowa, Natalia;
Elmore, Bradley O.;
Alexander, Susan M.;
Femling, Jon K.;
Gray, Brian M.;
DeLeo, Frank R.;
Otto, Michael;
Cheung, Ambrose L.;
Edwards, Bruce S.;
Sklar, Larry A.;
Horswill, Alexander R.;
Hall, Pamela R.;
Gresham, Hattie D.

Publication type:

Article

Mobile Genetic Element-Encoded Cytolysin Connects Virulence to Methicillin Resistance in MRSA.

Published in:

PLoS Pathogens, 2009, v. 5, n. 7, p. 1, doi. 10.1371/journal.ppat.1000533

By:

Queck, Shu Y.;
Khan, Burhan A.;
Rong Wang;
Bach, Thanh-Huy L.;
Kretschmer, Dorothee;
Liang Chen;
Kreiswirth, Barry N.;
Peschel, Andreas;
DeLeo, Frank R.;
Otto, Michael

Publication type:

Article

Genome-Wide Analysis of Group A Streptococci Reveals a Mutation That Modulates Global Phenotype and Disease Specificity.

Published in:

PLoS Pathogens, 2006, v. 2, n. 1, p. e5, doi. 10.1371/journal.ppat.0020005

By:

Sumby, Paul;
Whitney, Adeline R.;
Graviss, Edward A.;
DeLeo, Frank R.;
Musser, James M.

Publication type:

Article

Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection.

Published in:

Cellular Microbiology, 2007, v. 9, n. 5, p. 1172, doi. 10.1111/j.1462-5822.2006.00858.x

By:

Burlak, Christopher;
Hammer, Carl H.;
Robinson, Mary-Ann;
Whitney, Adeline R.;
McGavin, Martin J.;
Kreiswirth, Barry N.;
DeLeo, Frank R.

Publication type:

Article

Polysaccharide intercellular adhesin (PIA) protects Staphylococcus epidermidis against major components of the human innate immune system.

Published in:

Cellular Microbiology, 2004, v. 6, n. 3, p. 269, doi. 10.1046/j.1462-5822.2004.00367.x

By:

Vuong, Cuong;
Voyich, Jovanka M.;
Fischer, Elizabeth R.;
Braughton, Kevin R.;
Whitney, Adeline R.;
DeLeo, Frank R.;
Otto, Michael

Publication type:

Article

Innate Host Defense against Klebsiella pneumoniae and the Outlook for Development of Immunotherapies.

Published in:

Journal of Innate Immunity, 2022, v. 14, n. 3, p. 167, doi. 10.1159/000518679

By:

Opoku-Temeng, Clement;
Malachowa, Natalia;
Kobayashi, Scott D.;
DeLeo, Frank R.

Publication type:

Article

Neutrophils and Bacterial Immune Evasion.

Published in:

Journal of Innate Immunity, 2018, v. 10, n. 5-6, p. 432, doi. 10.1159/000487756

By:

Kobayashi, Scott D.;
Malachowa, Natalia;
DeLeo, Frank R.

Publication type:

Article

Phagocytosis and Killing of Staphylococcus aureus by Human Neutrophils.

Published in:

Journal of Innate Immunity, 2014, v. 6, n. 5, p. 639, doi. 10.1159/000360478

By:

Lu, Thea;
Porter, Adeline R.;
Kennedy, Adam D.;
Kobayashi, Scott D.;
DeLeo, Frank R.

Publication type:

Article

Systems Biology and Innate Immunity.

Published in:

Journal of Innate Immunity, 2013, v. 5, n. 2, p. 97, doi. 10.1159/000347135

By:

Kobayashi, Scott D.;
DeLeo, Frank R.

Publication type:

Article

Francisella tularensis Alters Human Neutrophil Gene Expression: Insights into the Molecular Basis of Delayed Neutrophil Apoptosis.

Published in:

Journal of Innate Immunity, 2013, v. 5, n. 2, p. 124, doi. 10.1159/000342430

By:

Schwartz, Justin T.;
Bandyopadhyay, Sarmistha;
Kobayashi, Scott D.;
McCracken, Jenna;
Whitney, adeline R.;
DeLeo, Frank R.;
allen, Lee-ann H.

Publication type:

Article

Rapid Neutrophil Destruction following Phagocytosis of Staphylococcus aureus.

Published in:

Journal of Innate Immunity, 2010, v. 2, n. 6, p. 560, doi. 10.1159/000317134

By:

Kobayashi, Scott D.;
Braughton, Kevin R.;
Palazzolo-Ballance, Amy M.;
Kennedy, Adam D.;
Sampaio, Elizabeth;
Kristosturyan, Ervand;
Whitney, Adeline R.;
Sturdevant, Daniel E.;
Dorward, David W.;
Holland, Steven M.;
Kreiswirth, Barry N.;
Musser, James M.;
DeLeo, Frank R.

Publication type:

Article

Identification of Outer Membrane and Exoproteins of Carbapenem-Resistant Multilocus Sequence Type 258 Klebsiella pneumoniae.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123219

By:

Brinkworth, Amanda J.;
Hammer, Carl H.;
Olano, L. Renee;
Kobayashi, Scott D.;
Chen, Liang;
Kreiswirth, Barry N.;
DeLeo, Frank R.

Publication type:

Article

Insights into the Staphylococcus aureus-Host Interface: Global Changes in Host and Pathogen Gene Expression in a Rabbit Skin Infection Model.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0117713

By:

Malachowa, Natalia;
Kobayashi, Scott D.;
Sturdevant, Daniel E.;
Scott, Dana P.;
DeLeo, Frank R.

Publication type:

Article

Global Changes in Staphylococcus aureus Gene Expression in Human Blood.

Published in:

PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018617

By:

Malachowa, Natalia;
Whitney, Adeline R.;
Kobayashi, Scott D.;
Sturdevant, Daniel E.;
Kennedy, Adam D.;
Braughton, Kevin R.;
Shabb, Duncan W.;
Diep, Binh An;
Chambers, Henry F.;
Otto, Michael;
DeLeo, Frank R.

Publication type:

Article

Identification of a Novel Staphylococcus aureus Two- Component Leukotoxin Using Cell Surface Proteomics.

Published in:

PLoS ONE, 2010, v. 5, n. 7, p. 1, doi. 10.1371/journal.pone.0011634

By:

Ventura, Christy L.;
Malachowa, Natalia;
Hammer, Carl H.;
Nardone, Glenn A.;
Robinson, Mary Ann;
Kobayashi, Scott D.;
DeLeo, Frank R.

Publication type:

Article

Phagocytosis of Staphylococcus aureus by Macrophages Exerts Cytoprotective Effects Manifested by the Upregulation of Antiapoptotic Factors.

Published in:

PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005210

By:

Koziel, Joanna;
Maciag-Gudowska, Agnieszka;
Mikolajczyk, Tomasz;
Bzowska, Malgorzata;
Sturdevant, Daniel E.;
Whitney, Adeline R.;
Shaw, Lindsey N.;
DeLeo, Frank R.;
Potempa, Jan

Publication type:

Article

Contribution of Panton-Valentine Leukocidin in Community-Associated Methicillin-Resistant Staphylococcus aureus Pathogenesis.

Published in:

PLoS ONE, 2008, v. 3, n. 9, p. 1, doi. 10.1371/journal.pone.0003198

By:

Binh An Diep;
Palazzolo-Ballance, Amy M.;
Tattevin, Pierre;
Li Basuino;
Braughton, Kevin R.;
Whitney, Adeline R.;
Liang Chen;
Kreiswirth, Barry N.;
Otto, Michael;
DeLeo, Frank R.;
Chambers, Henry F.

Publication type:

Article

Genome Sequence of a Lancefield Group C Streptococcus zooepidemicus Strain Causing Epidemic Nephritis: New Information about an Old Disease.

Published in:

PLoS ONE, 2008, v. 3, n. 8, p. 1, doi. 10.1371/journal.pone.0003026

By:

Beres, Stephen B.;
Sesso, Ricardo;
Pinto, Sergio Wyton L.;
Hoe, Nancy P.;
Porcella, Stephen F.;
DeLeo, Frank R.;
Musser, James M.

Publication type:

Article

Insight into structure-function relationship in phenol-soluble modulins using an alanine screen of the phenol-soluble modulin (PSM) α3 peptide.

Published in:

FASEB Journal, 2014, v. 28, n. 1, p. 153, doi. 10.1096/fj.13-232041

By:

Gordon Y. C. Cheung;
Kretschmer, Dorothee;
Shu Y. Queck;
Hwang-Soo Joo;
Rong Wang;
Anthony C. Duong;
Thuan H. Nguyen;
Bach, Thanh-Huy L.;
Porter, Adeline R.;
DeLeo, Frank R.;
Peschel, Andreas;
Otto, Michael

Publication type:

Article

Relapsing fever spirochaetes produce a serine protease that provides resistance to oxidative stress and killing by neutrophils.

Published in:

Molecular Microbiology, 2006, v. 60, n. 3, p. 710, doi. 10.1111/j.1365-2958.2006.05122.x

By:

Guyard, Cyril;
Battisti, James M.;
Raffel, Sandra J.;
Schrumpf, Merry E.;
Whitney, Adeline R.;
Krum, Jonathan G.;
Porcella, Stephen F.;
Rosa, Patricia A.;
DeLeo, Frank R.;
Schwan, Tom G.

Publication type:

Article

Reemergence of antibiotic-resistant Staphylococcus aureus in the genomics era.

Published in:

2009

By:

DeLeo, Frank R.;
Chambers, Henry F.

Publication type:

journal article

Key role of poly-ϒ-DL-glutamic acid in immune evasion and virulence of Staphylococcus epidermidis.

Published in:

Journal of Clinical Investigation, 2005, v. 115, n. 3, p. 688, doi. 10.1172/JCI200523523

By:

Kocianova, Stanislava;
Cuong Vuong;
Yufeng Yao;
Voyich, Jovanka M.;
Fischer, Elizabeth R.;
Deleo, Frank R.;
Otto, Michael

Publication type:

Article

Staphylococcus aureus survival in human blood.

Published in:

Virulence, 2011, v. 2, n. 6, p. 1, doi. 10.4161/viru.2.6.17732

By:

Malachowa, Natalia;
DeLeo, Frank R

Publication type:

Article

Mobile genetic elements of Staphylococcus aureus.

Published in:

Cellular & Molecular Life Sciences, 2010, v. 67, n. 18, p. 3057, doi. 10.1007/s00018-010-0389-4

By:

Malachowa, Natalia;
DeLeo, Frank R.

Publication type:

Article

A molecular trigger for intercontinental epidemics of group A Streptococcus.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 9, p. 3545, doi. 10.1172/JCI82478

By:

Luchang Zhu;
Olsen, Randall J.;
Nasser, Waleed;
Beres, Stephen B.;
Vuopio, Jaana;
Kristinsson, Karl G.;
Gottfredsson, Magnus;
Porter, Adeline R.;
DeLeo, Frank R.;
Musser, James M.

Publication type:

Article

Microbes and the fate of neutrophils.

Published in:

Immunological Reviews, 2023, v. 314, n. 1, p. 210, doi. 10.1111/imr.13163

By:

Kobayashi, Scott D.;
DeLeo, Frank R.;
Quinn, Mark T.

Publication type:

Article

A NET outcome.

Published in:

Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00365

By:

Thea Lu;
Kobayashi, Scott D.;
Quinn, Mark T.;
DeLeo, Frank R.

Publication type:

Article

A NET Outcome.

Published in:

Frontiers in Immunology, 2012, v. 3, p. 1, doi. 10.3389/fimmu.2012.00365

By:

Thea Lu;
Kobayashi, Scott D.;
Quinn, Mark T.;
DeLeo, Frank R.

Publication type:

Article

Dectin-1 promotes fungicidal activity of human neutrophils.

Published in:

European Journal of Immunology, 2007, v. 37, n. 2, p. 467, doi. 10.1002/eji.200636653

By:

Kennedy, Adam D.;
Willment, Janet A.;
Dorward, David W.;
Williams, David L.;
Brown, Gordon D.;
DeLeo, Frank R.

Publication type:

Article

ADAM17 activity during human neutrophil activation and apoptosis.

Published in:

European Journal of Immunology, 2006, v. 36, n. 4, p. 968, doi. 10.1002/eji.200535257

By:

Walcheck, Bruce;
Herrera, Amy H.;
Hill, Catherine St.;
Mattila, Polly E.;
Whitney, Adeline R.;
DeLeo, Frank R.

Publication type:

Article

Interaction of Staphylococci with Human B cells.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164410

By:

Nygaard, Tyler K.;
Kobayashi, Scott D.;
Freedman, Brett;
Porter, Adeline R.;
Voyich, Jovanka M.;
Otto, Michael;
Schneewind, Olaf;
DeLeo, Frank R.

Publication type:

Article

Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection.

Published in:

PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0158293

By:

Malachowa, Natalia;
Kobayashi, Scott D.;
Porter, Adeline R.;
Braughton, Kevin R.;
Scott, Dana P.;
Gardner, Donald J.;
Missiakas, Dominique M.;
Schneewind, Olaf;
DeLeo, Frank R.

Publication type:

Article

The SaeR/S Gene Regulatory System Is Essential for Innate Immune Evasion by Staphylococcus aureus.

Published in:

Journal of Infectious Diseases, 2009, v. 199, n. 11, p. 1698, doi. 10.1086/598967

By:

Voyich, Jovanka M.;
Cuong Vuong;
DeWald, Mark;
Nygaard, Tyler K.;
Kocianova, Stanislava;
Griffith, Shannon;
Jones, Jennifer;
Iverson, Courtney;
Sturdevant, Daniel E.;
Braughton, Kevin R.;
Whitney, Adeline R.;
Otto, Michael;
DeLeo, Frank R.

Publication type:

Article

Panton-Valentine Leukocidin Is Not a Virulence Determinant in Murine Models of Community-Associated Methicillin-Resistant Staphylococcus aureus Disease.

Published in:

Journal of Infectious Diseases, 2008, v. 198, n. 8, p. 1166, doi. 10.1086/592053

By:

Wardenburg, Juliane Bubeck;
Palazzolo-Ballance, Amy M.;
Otto, Michael;
Schneewind, Olaf;
DeLeo, Frank R.

Publication type:

Article

The Arginine Catabolic Mobile Element and Staphylococcal Chromosomal Cassette mec Linkage: Convergence of Virulence and Resistance in the USA300 Clone of Methicillin-Resistant Staphylococcus aureus.

Published in:

Journal of Infectious Diseases, 2008, v. 197, n. 11, p. 1523, doi. 10.1086/587907

By:

Diep, Binh An;
Stone, Gregory G.;
Basuino, Li;
Graber, Christopher J.;
Miller, Alita;
des Etages, Shelley-Ann;
Jones, Alison;
Palazzolo-Ballance, Amy M.;
Perdreau-Remington, Françoise;
Sensabaugh, George F.;
DeLeo, Frank R.;
Chambers, Henry F.

Publication type:

Article

Reply to Kernodle and to Schwartzman et al.

Published in:

2007

By:

Voyich, Jovanka M.;
Otto, Michael;
Mathema, Barun;
Kreiswirth, Barry N.;
DeLeo, Frank R.

Publication type:

Letter

Is Panton-Valentine Leukocidin the Major Virulence Determinant in Community-Associated Methicillin-Resistant Staphylococcus aureus Disease?

Published in:

Journal of Infectious Diseases, 2006, v. 194, n. 12, p. 1761, doi. 10.1086/509506

By:

Voyich, Jovanka M.;
Otto, Michael;
Mathema, Barun;
Braughton, Kevin R.;
Whitney, Adeline R.;
Welty, Diane;
Long, R. Daniel;
Dorward, David W.;
Gardner, Donald J.;
Lina, Gérard;
Kreiswirth, Barry N.;
DeLeo, Frank R.

Publication type:

Article

Transmission of Yersinia pestis from an Infectious Biofilm in the Flea Vector.

Published in:

Journal of Infectious Diseases, 2004, v. 190, n. 4, p. 783, doi. 10.1086/422695

By:

Jarrett, Clayton O.;
Deak, Eszter;
Isherwood, Karen E.;
Oyston, Petra C.;
Fischer, Elizabeth R.;
Whitney, Adeline R.;
Kobayashi, Scott D.;
Deleo, Frank R.;
Hinnebusch, B. Joseph

Publication type:

Article

Progress toward Characterization of the Group A Streptococcus Metagenome: Complete Genome Sequence of a Macrolide-Resistant Serotype M6 Strain.

Published in:

Journal of Infectious Diseases, 2004, v. 190, n. 4, p. 727, doi. 10.1086/422697

By:

Banks, David J.;
Porcella, Stephen F.;
Barbian, Kent D.;
Beres, Stephen B.;
Philips, Lauren E.;
Voyich, Jovanka M.;
Deleo, Frank R.;
Martin, Judith M.;
Somerville, Greg A.;
Musser, James M.

Publication type:

Article

Net confusion.

Published in:

Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00259

By:

Malachowa, Natalia;
Kobayashi, Scott D.;
Quinn, Mark T.;
DeLeo, Frank R.;
Witko-Sarsat, Veronique;
Fuchs, Tobias A.

Publication type:

Article

Toward an Understanding of the Evolution of Staphylococcus aureus Strain USA300 during Colonization in Community Households.

Published in:

Genome Biology & Evolution, 2012, v. 4, n. 12, p. 1275, doi. 10.1093/gbe/evs094

By:

Uhlemann, Anne-Catrin;
Kennedy, Adam D.;
Martens, Craig;
Porcella, Stephen F.;
DeLeo, Frank R.;
Lowy, Franklin D.

Publication type:

Article