Works by DeFronzo, Ralph A.
Results: 434
Hypoadiponectinemia Is Closely Associated with Impaired Nitric Oxide Synthase Activity in Skeletal Muscle of Type 2 Diabetic Subjects.
- Published in:
- Metabolic Syndrome & Related Disorders, 2010, v. 8, n. 5, p. 459, doi. 10.1089/met.2010.0018
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- Article
Plasma insulin is required for the increase in plasma angiopoietin‐like protein 8 in response to nutrient ingestion.
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- Diabetes/Metabolism Research & Reviews, 2023, v. 39, n. 6, p. 1, doi. 10.1002/dmrr.3643
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- Article
Exenatide modulates visual cortex responses.
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- 2019
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- Publication type:
- journal article
The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes.
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- Diabetes/Metabolism Research & Reviews, 2010, v. 26, n. 4, p. 280, doi. 10.1002/dmrr.1084
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- Article
Short-Term Exercise Training Improves Insulin Sensitivity but Does Not Inhibit Inflammatory Pathways in Immune Cells from Insulin-Resistant Subjects.
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- Journal of Diabetes Research, 2013, p. 1, doi. 10.1155/2013/107805
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- Article
Effect of a sustained reduction in plasma free fatty acid concentration on insulin signalling and inflammation in skeletal muscle from human subjects.
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- Journal of Physiology, 2013, v. 591, n. 11, p. 2897, doi. 10.1113/jphysiol.2012.247510
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- Article
Pioglitazone: inexpensive; very effective at reducing HbA<sub>1c</sub>; no evidence of bladder cancer risk; plenty of evidence of cardiovascular benefit.
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- Diabetic Medicine, 2019, v. 36, n. 9, p. 1185, doi. 10.1111/dme.14053
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- Article
The Insulin-Sensitizer Pioglitazone Remodels Adipose Tissue Phospholipids in Humans.
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- Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.784391
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- Article
Insulin resistance limits corneal nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control.
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- Journal of Diabetes Investigation, 2021, v. 12, n. 11, p. 2002, doi. 10.1111/jdi.13582
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- Article
Painful diabetic neuropathy is associated with increased nerve regeneration in patients with type 2 diabetes undergoing intensive glycemic control.
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- Journal of Diabetes Investigation, 2021, v. 12, n. 9, p. 1642, doi. 10.1111/jdi.13544
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- Article
Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial.
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- 2015
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- journal article
Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes.
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- JAMA: Journal of the American Medical Association, 2015, v. 314, n. 7, p. 687, doi. 10.1001/jama.2015.9676.
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- Article
Successful β cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1.
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- Cell Cycle, 2014, v. 13, n. 7, p. 1145, doi. 10.4161/cc.27997
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- Publication type:
- Article
The Use of Non-Insulin Anti-Diabetic Agents to Improve Glycemia Without Hypoglycemia in the Hospital Setting: Focus on Incretins.
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- Current Diabetes Reports, 2014, v. 14, n. 3, p. 1, doi. 10.1007/s11892-013-0466-9
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- Article
Efficacy and Safety of SGLT2 Inhibitors in the Treatment of Type 2 Diabetes Mellitus.
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- Current Diabetes Reports, 2012, v. 12, n. 3, p. 230, doi. 10.1007/s11892-012-0275-6
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- Article
Pathophysiology of prediabetes.
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- Current Diabetes Reports, 2009, v. 9, n. 3, p. 193, doi. 10.1007/s11892-009-0032-7
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- Article
Mitochondrial dysfunction, insulin resistance, and type 2 diabetes mellitus.
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- Current Diabetes Reports, 2008, v. 8, n. 3, p. 173, doi. 10.1007/s11892-008-0030-1
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- Article
Unexplained Residual Risk In Type 2 Diabetes: How Big Is The Problem?
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- Current Cardiology Reports, 2024, v. 26, n. 6, p. 623, doi. 10.1007/s11886-024-02055-0
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- Article
Insulin Resistance and Atherosclerosis: Implications for Insulin-Sensitizing Agents.
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- Endocrine Reviews, 2019, v. 40, n. 6, p. 1447, doi. 10.1210/er.2018-00141
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- Article
Cyclophosphamide and the kidney.
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- Cancer (0008543X), 1974, v. 33, n. 2, p. 483, doi. 10.1002/1097-0142(197402)33:2<483::AID-CNCR2820330224>3.0.CO;2-P
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- Article
Glucose-Mediated Glucose Disposal at Baseline Insulin Is Impaired in IFG.
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- 2018
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- journal article
Older Subjects With β-Cell Dysfunction Have an Accentuated Incretin Release.
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- 2018
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- journal article
Empagliflozin Treatment Is Associated With Improved ß-Cell Function in Type 2 Diabetes Mellitus.
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- Journal of Clinical Endocrinology & Metabolism, 2018, v. 103, n. 4, p. 1402, doi. 10.1210/jc.2017-01838
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- Publication type:
- Article
Empagliflozin Treatment Is Associated With Improved β-Cell Function in Type 2 Diabetes Mellitus.
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- 2018
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- Publication type:
- journal article
Efficacy of Exenatide Plus Pioglitazone Vs Basal/Bolus Insulin in T2DM Patients With Very High HbA1c.
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- 2017
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- Publication type:
- journal article
Empagliflozin Reduces Liver Fat in Individuals With and Without Diabetes.
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- Diabetes Care, 2024, v. 47, n. 4, p. 668, doi. 10.2337/dc23-1646
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- Publication type:
- Article
Longitudinal Effects of Glucose-Lowering Medications on β-Cell Responses and Insulin Sensitivity in Type 2 Diabetes: The GRADE Randomized Clinical Trial.
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- Diabetes Care, 2024, v. 47, n. 4, p. 580, doi. 10.2337/dc23-1070
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- Article
Impact of Insulin Sensitivity and β-Cell Function Over Time on Glycemic Outcomes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE): Differential Treatment Effects of Dual Therapy.
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- Diabetes Care, 2024, v. 47, n. 4, p. 571, doi. 10.2337/dc23-1059
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- Article
Distinct Mechanisms Responsible for the Increase in Glucose Production and Ketone Formation Caused by Empagliflozin in T2DM Patients.
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- Diabetes Care, 2023, v. 46, n. 5, p. 978, doi. 10.2337/dc22-0885
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- Article
Dapagliflozin Impairs the Suppression of Endogenous Glucose Production in Type 2 Diabetes Following Oral Glucose.
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- Diabetes Care, 2022, v. 45, n. 6, p. 1372, doi. 10.2337/dc21-1798
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- Article
Erratum. Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis. Diabetes Care 2021;44:1062-1069.
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- 2021
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- journal article
Comment on Piccinini and Bergman. The Measurement of Insulin Clearance. Diabetes Care 2020;43:2296-2302.
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- 2021
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- Publication type:
- Letter
Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis.
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- 2021
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- journal article
Association of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort.
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- 2021
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- journal article
Durability of Triple Combination Therapy Versus Stepwise Addition Therapy in Patients With New-Onset T2DM: 3-Year Follow-up of EDICT.
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- 2021
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- journal article
Clinical Parameters, Fuel Oxidation, and Glucose Kinetics in Patients With Type 2 Diabetes Treated With Dapagliflozin Plus Saxagliptin.
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- 2020
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- journal article
Newly Discovered Abnormal Glucose Tolerance in Patients With Acute Myocardial Infarction and Cardiovascular Outcomes: A Meta-analysis.
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- 2020
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- journal article
Combination Therapy With Canagliflozin Plus Liraglutide Exerts Additive Effect on Weight Loss, but Not on HbA<sub>1c</sub>, in Patients With Type 2 Diabetes.
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- 2020
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- Publication type:
- journal article
Increase in Endogenous Glucose Production With SGLT2 Inhibition Is Unchanged by Renal Denervation and Correlates Strongly With the Increase in Urinary Glucose Excretion.
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- 2020
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- journal article
Erratum. Cardiovascular Disease and Type 2 Diabetes: Has the Dawn of a New Era Arrived? Diabetes Care 2017;40:813-820.
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- 2017
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- journal article
Pioglitazone Improves Left Ventricular Diastolic Function in Subjects With Diabetes.
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- 2017
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- journal article
Is It Time to Change the Type 2 Diabetes Treatment Paradigm? Yes! GLP-1 RAs Should Replace Metformin in the Type 2 Diabetes Algorithm.
- Published in:
- 2017
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- Publication type:
- journal article
Erratum. Combination Therapy With Exenatide Plus Pioglitazone Versus Basal/Bolus Insulin in Patients With Poorly Controlled Type 2 Diabetes on Sulfonylurea Plus Metformin: The Qatar Study. Diabetes Care 2017;40:325-331.
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- 2017
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- journal article
Cardiovascular Disease and Type 2 Diabetes: Has the Dawn of a New Era Arrived?
- Published in:
- 2017
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- Publication type:
- journal article
Combination Therapy With Exenatide Plus Pioglitazone Versus Basal/Bolus Insulin in Patients With Poorly Controlled Type 2 Diabetes on Sulfonylurea Plus Metformin: The Qatar Study.
- Published in:
- 2017
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- Publication type:
- journal article
Dapagliflozin Enhances Fat Oxidation and Ketone Production in Patients With Type 2 Diabetes.
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- 2016
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- Publication type:
- journal article
Discordance Between Central (Brain) and Pancreatic Action of Exenatide in Lean and Obese Subjects.
- Published in:
- 2016
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- Publication type:
- journal article
Positioning SGLT2 Inhibitors/Incretin-Based Therapies in the Treatment Algorithm.
- Published in:
- 2016
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- journal article
SGLT2 Inhibitors and Cardiovascular Risk: Lessons Learned From the EMPA-REG OUTCOME Study.
- Published in:
- 2016
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- Publication type:
- journal article
The Primary Glucose-Lowering Effect of Metformin Resides in the Gut, Not the Circulation: Results From Short-term Pharmacokinetic and 12-Week Dose-Ranging Studies.
- Published in:
- 2016
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- Publication type:
- journal article