Works matching AU DeFronzo, R A

Results: 94

The effect of muraglitazar on adiponectin signalling, mitochondrial function and fat oxidation genes in human skeletal muscle in vivo.

Published in:

Diabetic Medicine, 2015, v. 32, n. 5, p. 657, doi. 10.1111/dme.12664

By:

Coletta, D. K.;
Fernandez, M.;
Cersosimo, E.;
Gastaldelli, A.;
Musi, N.;
DeFronzo, R. A.

Publication type:

Article

Vanadyl Sulfate Improves Hepatic and Muscle Insulin Sensitivity in Type 2 Diabetes.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2001, v. 86, n. 3, p. 1410, doi. 10.1210/jc.86.3.1410

By:

CUSI, K.;
CUKIER, S.;
DEFRONZO, R. A.;
TORRES, M.;
PUCHULU, F. M.;
PEREIRA REDONDO, J. C.

Publication type:

Article

Lentivirus shRNA Grb10 targeting the pancreas induces apoptosis and improved glucose tolerance due to decreased plasma glucagon levels.

Published in:

Diabetologia, 2012, v. 55, n. 3, p. 719, doi. 10.1007/s00125-011-2414-z

By:

Doiron, B.;
Hu, W.;
Norton, L.;
DeFronzo, R.

Publication type:

Article

Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism.

Published in:

Diabetologia, 2011, v. 54, n. 12, p. 3132, doi. 10.1007/s00125-011-2289-z

By:

Norton, L.;
Fourcaudot, M.;
Abdul-Ghani, M.;
Winnier, D.;
Mehta, F.;
Jenkinson, C.;
DeFronzo, R.

Publication type:

Article

Erratum to: Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis.

Published in:

2010

By:

Schernthaner, G.;
Barnett, A.;
Betteridge, D.;
Carmena, R.;
Ceriello, A.;
Charbonnel, B.;
Hanefeld, M.;
Lehmann, R.;
Malecki, M.;
Nesto, R.;
Pirags, V.;
Scheen, A.;
Seufert, J.;
Sjöholm, Å.;
Tsatsoulis, A.;
DeFronzo, R.

Publication type:

Correction Notice

Is the ADA/EASD algorithm for the management of type 2 diabetes (January 2009) based on evidence or opinion? A critical analysis.

Published in:

2010

By:

Schernthaner, G.;
Barnett, A.;
Betteridge, D.;
Carmena, R.;
Ceriello, A.;
Charbonnel, B.;
Hanefeld, M.;
Lehmann, R.;
Malecki, M.;
Nesto, R.;
Pirags, V.;
Scheen, A.;
Seufert, J.;
Sjohölm, A.;
Tsatsoulis, A.;
DeFronzo, R.

Publication type:

Editorial

Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009.

Published in:

Diabetologia, 2010, v. 53, n. 7, p. 1270, doi. 10.1007/s00125-010-1684-1

By:

DeFronzo, R.

Publication type:

Article

Determinants of glucose tolerance in impaired glucose tolerance at baseline in the Actos Now for Prevention of Diabetes (ACT NOW) study.

Published in:

Diabetologia, 2010, v. 53, n. 3, p. 435, doi. 10.1007/s00125-009-1614-2

By:

DeFronzo, R.;
Banerji, M.;
Bray, G.;
Buchanan, T.;
Clement, S.;
Henry, R.;
Kitabchi, A.;
Mudaliar, S.;
Musi, N.;
Ratner, R.;
Reaven, P.;
Schwenke, D.;
Stentz, F.;
Tripathy, D.

Publication type:

Article

Impaired regulation of the TNF-α converting enzyme/tissue inhibitor of metalloproteinase 3 proteolytic system in skeletal muscle of obese type 2 diabetic patients: a new mechanism of insulin resistance in humans.

Published in:

Diabetologia, 2009, v. 52, n. 10, p. 2169, doi. 10.1007/s00125-009-1451-3

By:

Monroy, A.;
Kamath, S.;
Chavez, A.;
Centonze, V.;
Veerasamy, M.;
Barrentine, A.;
Wewer, J.;
Coletta, D.;
Jenkinson, C.;
Jhingan, R.;
Smokler, D.;
Reyna, S.;
Musi, N.;
Khokka, R.;
Federici, M.;
Tripathy, D.;
DeFronzo, R.;
Folli, F.

Publication type:

Article

Mitochondrial reactive oxygen species generation in obese non-diabetic and type 2 diabetic participants.

Published in:

Diabetologia, 2009, v. 52, n. 4, p. 574, doi. 10.1007/s00125-009-1264-4

By:

Abdul-Ghani, M.;
Jani, R.;
Chavez, A.;
Molina-Carrion, M.;
Tripathy, D.;
DeFronzo, R.

Publication type:

Article

Pioglitazone stimulates AMP-activated protein kinase signalling and increases the expression of genes involved in adiponectin signalling, mitochondrial function and fat oxidation in human skeletal muscle in vivo: a randomised trial.

Published in:

Diabetologia, 2009, v. 52, n. 4, p. 723, doi. 10.1007/s00125-008-1256-9

By:

Coletta, D.;
Sriwijitkamol, A.;
Wajcberg, E.;
Tantiwong, P.;
Li, M.;
Prentki, M.;
Madiraju, M.;
Jenkinson, C.;
Cersosimo, E.;
Musi, N.;
DeFronzo, R.

Publication type:

Article

Effects of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus.

Published in:

Diabetologia, 2007, v. 50, n. 8, p. 1723, doi. 10.1007/s00125-007-0698-9

By:

Bajaj, M.;
Suraamornkul, S.;
Hardies, L.;
Glass, L.;
Musi, N.;
DeFronzo, R.

Publication type:

Article

Association between variants in the genes for adiponectin and its receptors with insulin resistance syndrome (IRS)-related phenotypes in Mexican Americans.

Published in:

Diabetologia, 2006, v. 49, n. 10, p. 2317, doi. 10.1007/s00125-006-0384-3

By:

Richardson, D. K.;
Schneider, J.;
Fourcaudot, M. J.;
Rodriguez, L. M.;
Arya, R.;
Dyer, T. D.;
Almasy, L.;
Blangero, J.;
Stern, M. P.;
DeFronzo, R. A.;
Duggirala, R.;
Jenkinson, C. P.

Publication type:

Article

To: Godsland IF, Jeffs JA, Johnston DG (2004) Loss of beta cell function as fasting glucose increases in the non-diabetic range. Diabetologia 47:1157–1166.

Published in:

2005

By:

Abdul-Ghani, M. A.;
DeFronzo, R. A.

Publication type:

Letter

Reply to Comment on: Gastaldelli A, Ferrannini E, Miyazaki Y, Matsuda M, DeFronzo RA (2004) Beta cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia 43:31-39.

Published in:

2004

By:

Gastaldelli, A.;
Ferrannini, E.;
Miyazaki, Y.;
Matsuda, M.;
DeFronzo, R.

Publication type:

Letter

Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes Adiponectin receptors and insulin sensitivity.

Published in:

Diabetologia, 2004, v. 47, n. 5, p. 816, doi. 10.1007/s00125-004-1359-x

By:

Civitarese, A. E.;
Jenkinson, C. P.;
Richardson, D.;
Bajaj, M.;
Cusi, K.;
Kashyap, S.;
Berria, R.;
Belfort, R.;
DeFronzo, R. A.;
Mandarino, L. J.;
Ravussin, E.

Publication type:

Article

Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study A. Gastaldelli et al.: Beta -cell dysfunction and glucose intolerance.

Published in:

Diabetologia, 2004, v. 47, n. 1, p. 31, doi. 10.1007/s00125-003-1263-9

By:

Gastaldelli, A.;
Ferrannini, E.;
Miyazaki, Y.;
Matsuda, M.;
DeFronzo, R. A.

Publication type:

Article

Predominant role of reduced beta-cell sensitivity to glucose over insulin resistance in impaired glucose tolerance E. Ferrannini et al.: Beta-cell function in IGT.

Published in:

Diabetologia, 2003, v. 46, n. 9, p. 1211, doi. 10.1007/s00125-003-1169-6

By:

Ferrannini, E.;
Gastaldelli, A.;
Miyazaki, Y.;
Matsuda, M.;
Pettiti, M.;
Natali, A.;
Mari, A.;
DeFronzo, R. A.

Publication type:

Article

Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in Type II diabetic patients.

Published in:

Diabetologia, 2001, v. 44, n. 12, p. 2210, doi. 10.1007/s001250100031

By:

Miyazaki, Y.;
Glass, L.;
Triplitt, C.;
Matsuda, M.;
Cusi, K.;
Mahankali, A.;
Mahankali, S.;
Mandarino, L. J.;
DeFronzo, R. A.

Publication type:

Article

Skeletal muscle insulin resistance in normoglycemic subjects with a strong family history of type 2 diabetes is associated with decreased insulin-stimulated insulin receptor substrate-1 tyrosine phosphorylation.

Published in:

2001

By:

Pratipanawatr, Wilailak;
Pratipanawatr, Thongchai;
Cusi, Kenneth;
Berria, Rachele;
Adams, John M.;
Jenkinson, Christopher P.;
Maezono, Katsumi;
DeFronzo, Ralph A.;
Mandarino, Lawrence J.;
Pratipanawatr, W;
Pratipanawatr, T;
Cusi, K;
Berria, R;
Adams, J M;
Jenkinson, C P;
Maezono, K;
DeFronzo, R A;
Mandarino, L J

Publication type:

journal article

Seven days of euglycemic hyperinsulinemia induces insulin resistance for glucose metabolism but not hypertension, elevated catecholamine levels, or increased sodium retention in conscious normal rats.

Published in:

1997

By:

Koopmans, Sietse J.;
Ohman, Lynne;
Haywood, Joseph R.;
Mandarino, Lawrence J.;
DeFronzo, Ralph A.;
Koopmans, S J;
Ohman, L;
Haywood, J R;
Mandarino, L J;
DeFronzo, R A

Publication type:

journal article

Increased glutamine:fructose-6-phosphate amidotransferase activity in skeletal muscle of patients with NIDDM.

Published in:

1996

By:

Yki-Järvinen, Hannele;
Daniels, Marc C.;
Virkamäki, Antti;
Mäkimattila, Sari;
DeFronzo, Ralph A.;
McClain, Don;
Yki-Järvinen, H;
Daniels, M C;
Virkamäki, A;
Mäkimattila, S;
DeFronzo, R A;
McClain, D

Publication type:

journal article

Effects of angiotensin-converting enzyme inhibitors, Ca2+ channel antagonists, and alpha-adrenergic blockers on glucose and lipid metabolism in NIDDM patients with hypertension.

Published in:

1995

By:

Giordano, Mauro;
Matsuda, Masafumi;
Sanders, Leonard;
Canessa, Mitzy L.;
DeFronzo, Ralph A.;
Giordano, M;
Matsuda, M;
Sanders, L;
Canessa, M L;
DeFronzo, R A

Publication type:

journal article

Bedtime insulin/daytime glipizide. Effective therapy for sulfonylurea failures in NIDDM.

Published in:

1995

By:

Shank, M L;
Del Prato, S;
DeFronzo, R A

Publication type:

journal article

In vivo glucose metabolism in obese and type II diabetic subjects with or without hypertension.

Published in:

1993

By:

Bonora, Enzo;
Bonadonna, Riccardo C.;
Del Prato, Stefano;
Gulli, Giovanni;
Solini, Anna;
Matsuda, Masafumi;
Defronzo, Ralph A.;
Bonora, E;
Bonadonna, R C;
Del Prato, S;
Gulli, G;
Solini, A;
Matsuda, M;
DeFronzo, R A

Publication type:

journal article

Glucose transport in human skeletal muscle. The in vivo response to insulin.

Published in:

1993

By:

Bonadonna, R C;
Saccomani, M P;
Seely, L;
Zych, K S;
Ferrannini, E;
Cobelli, C;
DeFronzo, R A

Publication type:

journal article

The metabolic profile of NIDDM is fully established in glucose-tolerant offspring of two Mexican-American NIDDM parents.

Published in:

1992

By:

Gulli, Giovanni;
Ferrannini, Eleuterio;
Stern, Michael;
Haffner, Steven;
DeFronzo, Ralph A.;
Gulli, G;
Ferrannini, E;
Stern, M;
Haffner, S;
DeFronzo, R A

Publication type:

journal article

Metabolic effects of IGF-I in diabetic rats.

Published in:

1991

By:

Rossetti, Luciano;
Frontoni, Simona;
Dimarchi, Richard;
DeFronzo, Ralph A.;
Giaccari, Andrea;
Rossetti, L;
Frontoni, S;
Dimarchi, R;
DeFronzo, R A;
Giaccari, A

Publication type:

journal article

Leucine metabolism in IDDM. Role of insulin and substrate availability.

Published in:

1990

By:

Luzi, L;
Castellino, P;
Simonson, D C;
Petrides, A S;
DeFronzo, R A

Publication type:

journal article

Metabolic effects of low-dose insulin therapy on glucose metabolism in diabetic ketoacidosis.

Published in:

1988

By:

Luzi, Livio;
Barrett, Eugene J.;
Groop, Leif C.;
Ferrannini, Eleuterio;
DeFronzo, Ralph A.;
Luzi, L;
Barrett, E J;
Groop, L C;
Ferrannini, E;
DeFronzo, R A

Publication type:

journal article

Measurement of L-[1-14C]leucine kinetics in splanchnic and leg tissues in humans. Effect of amino acid infusion.

Published in:

1988

By:

Gelfand, Robert A.;
Glickman, Morton G.;
Castellino, Pietro;
Louard, Rita J.;
DeFronzo, Ralph A.;
Gelfand, R A;
Glickman, M G;
Castellino, P;
Louard, R J;
DeFronzo, R A

Publication type:

journal article

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

Published in:

1988

By:

DeFronzo, R A

Publication type:

journal article

Splanchnic amino acid and glucose metabolism during amino acid infusion in dogs.

Published in:

1988

By:

Ferrannini, Eleuterio;
Defronzo, Ralph A.;
Gusberg, Richard;
Tepler, Jeffery;
Jacob, Ralph;
Aaron, Michael;
Smith, Douglas;
Barrett, Eugene J.;
Ferrannini, E;
DeFronzo, R A;
Gusberg, R;
Tepler, J;
Jacob, R;
Aaron, M;
Smith, D;
Barrett, E J

Publication type:

journal article

Effect of physical training on insulin action in obesity.

Published in:

1987

By:

DeFronzo, Ralph A.;
Sherwin, Robert S.;
Kraemer, Nancy;
DeFronzo, R A;
Sherwin, R S;
Kraemer, N

Publication type:

journal article

Different effects of glyburide and glipizide on insulin secretion and hepatic glucose production in normal and NIDDM subjects.

Published in:

1987

By:

Groop, Leif;
Luzi, Livio;
Melander, Arne;
Groop, Per-Henrik;
Ratheiser, Klaus;
Simonson, Donald C.;
DeFronzo, Ralph A.;
Groop, L;
Luzi, L;
Melander, A;
Groop, P H;
Ratheiser, K;
Simonson, D C;
DeFronzo, R A

Publication type:

journal article

Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes.

Published in:

1987

By:

Felber, Jean-Pierre;
Ferrannini, Eleuterio;
Golay, Alain;
Meyer, Hans U.;
Theibaud, Daniel;
Curchod, Bernard;
Maeder, Evelyn;
Jequier, Eric;
DeFronzo, Ralph A.;
Felber, J P;
Ferrannini, E;
Golay, A;
Meyer, H U;
Theibaud, D;
Curchod, B;
Maeder, E;
Jequier, E;
DeFronzo, R A

Publication type:

journal article

Rate of glucose fall does not affect counterregulatory hormone responses to hypoglycemia in normal and diabetic humans.

Published in:

1987

By:

Amiel, Stephanie A.;
Simonson, Donald C.;
Tamborlane, William V.;
DeFronzo, Ralph A.;
Sherwin, Robert S.;
Amiel, S A;
Simonson, D C;
Tamborlane, W V;
DeFronzo, R A;
Sherwin, R S

Publication type:

journal article

Effect of glyburide on glycemic control, insulin requirement, and glucose metabolism in insulin-treated diabetic patients.

Published in:

1987

By:

Simonson, Donald C.;
Delprato, Stefano;
Castellino, Pietro;
Groop, Leif;
DeFronzo, Ralph A.;
Simonson, D C;
Delprato, S;
Castellino, P;
Groop, L;
DeFronzo, R A

Publication type:

journal article

Improved insulin sensitivity in patients with type I diabetes mellitus after CSII.

Published in:

1985

By:

Simonson, D C;
Tamborlane, W V;
Sherwin, R S;
Smith, J D;
DeFronzo, R A

Publication type:

journal article

The disposal of an oral glucose load in healthy subjects. A quantitative study.

Published in:

1985

By:

Ferrannini, Eleuterio;
Bjorkman, Ola;
Reichard Jr., George A.;
Pilo, Alessandro;
Olsson, Maggie;
Wahren, John;
DeFronzo, Ralph A.;
Ferrannini, E;
Bjorkman, O;
Reichard, G A Jr;
Pilo, A;
Olsson, M;
Wahren, J;
DeFronzo, R A

Publication type:

journal article

Mechanism of improvement in glucose metabolism after chronic glyburide therapy.

Published in:

1984

By:

Simonson, Donald C.;
Ferrannini, Eleuterio;
Bevilacqua, Stefano;
Smith, Douglas;
Barrett, Eugene;
Carlson, Rodney;
DeFronzo, Ralph A.;
Simonson, D C;
Ferrannini, E;
Bevilacqua, S;
Smith, D;
Barrett, E;
Carlson, R;
DeFronzo, R A

Publication type:

journal article

Impairment of insulin-mediated glucose metabolism by hyperosmolality in man.

Published in:

1983

By:

Bratusch-Marrain, Paul R.;
DeFronzo, Ralph A.;
Bratusch-Marrain, P R;
DeFronzo, R A

Publication type:

journal article

Splanchnic and peripheral disposal of oral glucose in man.

Published in:

1983

By:

Katz, Lee D.;
Glickman, Morton G.;
Rapoport, Stanley;
Ferrannini, Eleuterio;
DeFronzo, Ralph A.;
Katz, L D;
Glickman, M G;
Rapoport, S;
Ferrannini, E;
DeFronzo, R A

Publication type:

journal article

NIA0002 Novel role for adiponectin pathway in human skeletal muscle bioenergetics.

Published in:

Obesity Reviews, 2006, v. 7, p. 37, doi. 10.1111/j.1467-7881.2006.00280_8.x

By:

Civitarese, A. E.;
Nawrocki, A. R.;
Ukropcova, B.;
Carling, S.;
Hulver, M.;
DeFronzo, R. A.;
Mandarino, L.;
Scherer, P.;
Smith, S. R.;
Ravussin, E.

Publication type:

Article

Plasma resistin concentration, hepatic fat content, and hepatic and peripheral insulin resistance in pioglitazone-treated type II diabetic patients.

Published in:

International Journal of Obesity & Related Metabolic Disorders, 2004, v. 28, n. 6, p. 783, doi. 10.1038/sj.ijo.0802625

By:

Bajaj, M.;
Suraamornkull, S.;
Hardies, L. J.;
Pratipanawatr, T.;
DeFronzo, R. A.

Publication type:

Article

Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone.

Published in:

2001

By:

Miyazaki, Yoshinori;
Mahankali, Archana;
Matsuda, Masafumi;
Glass, Leonard;
Mahankali, Srikanth;
Ferrannini, Eleuterio;
Cusi, Kenneth;
Mandarino, Lawrence J.;
DeFronzo, Ralph A.;
Miyazaki, Y;
Mahankali, A;
Matsuda, M;
Glass, L;
Mahankali, S;
Ferrannini, E;
Cusi, K;
Mandarino, L J;
DeFronzo, R A

Publication type:

journal article

The GENNID Study. A resource for mapping the genes that cause NIDDM.

Published in:

1996

By:

Raffel, L J;
Robbins, D C;
Norris, J M;
Boerwinkle, E;
DeFronzo, R A;
Elbein, S C;
Fujimoto, W;
Hanis, C L;
Kahn, S E;
Permutt, M A;
Chiu, K C;
Cruz, J;
Ehrmann, D A;
Robertson, R P;
Rotter, J I;
Buse, J

Publication type:

journal article

Pathogenesis of NIDDM. A balanced overview.

Published in:

1992

By:

DeFronzo, R A;
Bonadonna, R C;
Ferrannini, E

Publication type:

journal article

Dose-dependent effects of glyburide on insulin secretion and glucose uptake in humans.

Published in:

1991

By:

Groop, Leif C.;
Barzilai, Nir;
Ratheiser, Klaus;
Luzi, Livio;
Wåhlin-Boll, Elisabeth;
Melander, Arne;
DeFronzo, Ralph A.;
Groop, L C;
Barzilai, N;
Ratheiser, K;
Luzi, L;
Wåhlin-Boll, E;
Melander, A;
DeFronzo, R A

Publication type:

journal article

Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease.

Published in:

1991

By:

DeFronzo, R A;
Ferrannini, E

Publication type:

journal article