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Targeting S100A9 protein affects mTOR-ER stress signaling and increases venetoclax sensitivity in Acute Myeloid Leukemia.
Published in:
Blood Cancer Journal, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41408-023-00962-z
By:
- Fan, Rong;
- Satilmis, Hatice;
- Vandewalle, Niels;
- Verheye, Emma;
- De Bruyne, Elke;
- Menu, Eline;
- De Beule, Nathan;
- De Becker, Ann;
- Ates, Gamze;
- Massie, Ann;
- Kerre, Tessa;
- Törngren, Marie;
- Eriksson, Helena;
- Vanderkerken, Karin;
- Breckpot, Karine;
- Maes, Ken;
- De Veirman, Kim
Publication type:
Article
Myeloid-derived suppressor cells as therapeutic target in hematological malignancies.
Published in:
Frontiers in Oncology, 2014, v. 4, p. 1, doi. 10.3389/fonc.2014.00349
By:
- De Veirman, Kim;
- Valckenborgh, Els Van;
- De Bruyne, Elke;
- Menu, Eline;
- Riet, Ivan Van;
- Vanderkerken, Karin;
- Lahmar, Qods;
- Geeraerts, Xenia;
- Van Ginderachter, Jo A.
Publication type:
Article
Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis.
Published in:
Journal of Pathology, 2023, v. 260, n. 2, p. 112, doi. 10.1002/path.6066
By:
- Van der Vreken, Arne;
- Oudaert, Inge;
- Ates, Gamze;
- Faict, Sylvia;
- Vlummens, Philip;
- Satilmis, Hatice;
- Fan, Rong;
- Maes, Anke;
- Massie, Ann;
- De Veirman, Kim;
- De Bruyne, Elke;
- Vanderkerken, Karin;
- Menu, Eline
Publication type:
Article
Targeting the β<sub>2</sub>‐adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism.
Published in:
Journal of Pathology, 2023, v. 259, n. 1, p. 69, doi. 10.1002/path.6020
By:
- Satilmis, Hatice;
- Verheye, Emma;
- Vlummens, Philip;
- Oudaert, Inge;
- Vandewalle, Niels;
- Fan, Rong;
- Knight, Jennifer M;
- De Beule, Nathan;
- Ates, Gamze;
- Massie, Ann;
- Moreaux, Jerome;
- Maes, Anke;
- De Bruyne, Elke;
- Vanderkerken, Karin;
- Menu, Eline;
- Sloan, Erica K;
- De Veirman, Kim
Publication type:
Article
Tumour-associated macrophage-mediated survival of myeloma cells through STAT3 activation.
Published in:
Journal of Pathology, 2017, v. 241, n. 4, p. 534, doi. 10.1002/path.4860
By:
- De Beule, Nathan;
- De Veirman, Kim;
- Maes, Ken;
- De Bruyne, Elke;
- Menu, Eline;
- Breckpot, Karine;
- De Raeve, Hendrik;
- Van Rampelbergh, Rian;
- Van Ginderachter, Jo A;
- Schots, Rik;
- Van Valckenborgh, Els;
- Vanderkerken, Karin
Publication type:
Article
Multiple myeloma exosomes establish a favourable bone marrow microenvironment with enhanced angiogenesis and immunosuppression.
Published in:
Journal of Pathology, 2016, v. 239, n. 2, p. 162, doi. 10.1002/path.4712
By:
- Wang, Jinheng;
- De Veirman, Kim;
- Faict, Sylvia;
- Frassanito, Maria Antonia;
- Ribatti, Domenico;
- Vacca, Angelo;
- Menu, Eline
Publication type:
Article
Dendritic Cell-Based Immunotherapy in Multiple Myeloma: Challenges, Opportunities, and Future Directions.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 904, doi. 10.3390/ijms23020904
By:
- Verheye, Emma;
- Bravo Melgar, Jesús;
- Deschoemaeker, Sofie;
- Raes, Geert;
- Maes, Anke;
- De Bruyne, Elke;
- Menu, Eline;
- Vanderkerken, Karin;
- Laoui, Damya;
- De Veirman, Kim
Publication type:
Article
Metabolic Features of Multiple Myeloma.
Published in:
International Journal of Molecular Sciences, 2018, v. 19, n. 4, p. 1200, doi. 10.3390/ijms19041200
By:
- El Arfani, Chaima;
- De Veirman, Kim;
- Maes, Ken;
- De Bruyne, Elke;
- Menu, Eline
Publication type:
Article
Effect of the HDAC inhibitor vorinostat on the osteogenic differentiation of mesenchymal stem cells in vitro and bone formation in vivo.
Published in:
Acta Pharmacologica Sinica, 2013, v. 34, n. 5, p. 699, doi. 10.1038/aps.2012.182
By:
- Xu, Song;
- De Veirman, Kim;
- Evans, Holly;
- Santini, Gaia Cecilia;
- Vande Broek, Isabelle;
- Leleu, Xavier;
- De Becker, Ann;
- Van Camp, Ben;
- Croucher, Peter;
- Vanderkerken, Karin;
- Van Riet, Ivan
Publication type:
Article
The prognostic value and therapeutic targeting of myeloid-derived suppressor cells in hematological cancers.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1016059
By:
- Rong Fan;
- De Beule, Nathan;
- Maes, Anke;
- De Bruyne, Elke;
- Menu, Eline;
- Vanderkerken, Karin;
- Maes, Ken;
- Breckpot, Karine;
- De Veirman, Kim
Publication type:
Article
Radiotheranostic Agents in Hematological Malignancies.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.911080
By:
- Caers, Jo;
- Duray, Elodie;
- Vrancken, Louise;
- Marcion, Guillaume;
- Bocuzzi, Valentina;
- De Veirman, Kim;
- Krasniqi, Ahmet;
- Lejeune, Margaux;
- Withofs, Nadia;
- Devoogdt, Nick;
- Dumoulin, Mireille;
- Karlström, Amelie Eriksson;
- D'Huyvetter, Matthias
Publication type:
Article
ER stress arm XBP1s plays a pivotal role in proteasome inhibition-induced bone formation.
Published in:
Stem Cell Research & Therapy, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13287-020-02037-3
By:
- Zhang, Dan;
- De Veirman, Kim;
- Fan, Rong;
- Jian, Qiang;
- Zhang, Yuchen;
- Lei, Li;
- Evans, Holly;
- Wang, Yanmeng;
- Lei, Lei;
- Wang, Baiyan;
- Williamson, Ramone A.;
- Chantry, Andrew;
- He, Pengcheng;
- Li, Ang;
- De Raeve, Hendrik;
- Vanderkerken, Karin;
- He, Aili;
- Hu, Jinsong
Publication type:
Article
Upregulation of miR-135b Is Involved in the Impaired Osteogenic Differentiation of Mesenchymal Stem Cells Derived from Multiple Myeloma Patients.
Published in:
PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079752
By:
- Xu, Song;
- Cecilia Santini, Gaia;
- De Veirman, Kim;
- Vande Broek, Isabelle;
- Leleu, Xavier;
- De Becker, Ann;
- Van Camp, Ben;
- Vanderkerken, Karin;
- Van Riet, Ivan
Publication type:
Article
The Transfer of Sphingomyelinase Contributes to Drug Resistance in Multiple Myeloma.
Published in:
Cancers, 2019, v. 11, n. 12, p. 1823, doi. 10.3390/cancers11121823
By:
- Faict, Sylvia;
- Oudaert, Inge;
- D'Auria, Ludovic;
- Dehairs, Jonas;
- Maes, Ken;
- Vlummens, Philip;
- De Veirman, Kim;
- De Bruyne, Elke;
- Fostier, Karel;
- Vande Broek, Isabelle;
- Schots, Rik;
- Vanderkerken, Karin;
- Swinnen, Johannes V.;
- Menu, Eline
Publication type:
Article
AXL Receptor Tyrosine Kinase as a Therapeutic Target in Hematological Malignancies: Focus on Multiple Myeloma.
Published in:
Cancers, 2019, v. 11, n. 11, p. 1727, doi. 10.3390/cancers11111727
By:
- Yan, Siyang;
- Vandewalle, Niels;
- De Beule, Nathan;
- Faict, Sylvia;
- Maes, Ken;
- De Bruyne, Elke;
- Menu, Eline;
- Vanderkerken, Karin;
- De Veirman, Kim
Publication type:
Article
Cancer Associated Fibroblasts and Tumor Growth: Focus on Multiple Myeloma.
Published in:
Cancers, 2014, v. 6, n. 3, p. 1363, doi. 10.3390/cancers6031363
By:
- De Veirman, Kim;
- Rao, Luigia;
- De Bruyne, Elke;
- Menu, Eline;
- Van Valckenborgh, Els;
- Van Riet, Ivan;
- Frassanito, Maria Antonia;
- Di Marzo, Lucia;
- Vacca, Angelo;
- Vanderkerken, Karin
Publication type:
Article
RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1286700
By:
- Emde-Rajaratnam, Martina;
- Beck, Susanne;
- Benes, Vladimir;
- Salwender, Hans;
- Bertsch, Uta;
- Scheid, Christoph;
- Hänel, Mathias;
- Weisel, Katja;
- Hielscher, Thomas;
- Raab, Marc S.;
- Goldschmidt, Hartmut;
- Jauch, Anna;
- Maes, Ken;
- De Bruyne, Elke;
- Menu, Eline;
- De Veirman, Kim;
- Moreaux, Jéró me;
- Vanderkerken, Karin;
- Seckinger, Anja;
- Hose, Dirk
Publication type:
Article
The Use of Murine Models for Studying Mechanistic Insights of Genomic Instability in Multiple Myeloma.
Published in:
Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00740
By:
- Vlummens, Philip;
- De Veirman, Kim;
- Menu, Eline;
- De Bruyne, Elke;
- Offner, Fritz;
- Vanderkerken, Karin;
- Maes, Ken
Publication type:
Article
Targeting mTOR signaling pathways in multiple myeloma: biology and implication for therapy.
Published in:
Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01699-3
By:
- Wang, Yanmeng;
- Vandewalle, Niels;
- De Veirman, Kim;
- Vanderkerken, Karin;
- Menu, Eline;
- De Bruyne, Elke
Publication type:
Article
The antigen‐binding moiety in the driver's seat of CARs.
Published in:
Medicinal Research Reviews, 2022, v. 42, n. 1, p. 306, doi. 10.1002/med.21818
By:
- Hanssens, Heleen;
- Meeus, Fien;
- De Veirman, Kim;
- Breckpot, Karine;
- Devoogdt, Nick
Publication type:
Article
Complement C3a activates osteoclasts by regulating the PI3K/PDK1/SGK3 pathway in patients with multiple myeloma.
Published in:
Cancer Biology & Medicine, 2021, v. 18, n. 3, p. 721, doi. 10.20892/j.issn.2095-3941.2020.0430
By:
- Fengjuan Jiang;
- Hui Liu;
- Fengping Peng;
- Zhaoyun Liu;
- Kai Ding;
- Jia Song;
- Lijuan Li;
- Jin Chen;
- Qing Shao;
- Siyang Yan;
- De Veirman, Kim;
- Vanderkerken, Karin;
- Rong Fu
Publication type:
Article
Mesenchymal Stromal Cell Sialylation Modulates Antitumor Immune Responses In Multiple Myeloma.
Published in:
Clinical Lymphoma, Myeloma & Leukemia, 2019, v. 19, p. e93, doi. 10.1016/j.clml.2019.09.152
By:
- Lynch, Kevin;
- De Veirman, Kim;
- Egan, Hannah;
- Leonard, Niamh;
- O'Malley, Grace;
- Ritter, Thomas;
- Ryan, Aideen;
- O'Dwyer, Michael
Publication type:
Article
The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma.
Published in:
2019
By:
- Maes, Anke;
- Maes, Ken;
- De Raeve, Hendrik;
- De Smedt, Eva;
- Vlummens, Philip;
- Szablewski, Vanessa;
- Devin, Julie;
- Faict, Sylvia;
- De Veirman, Kim;
- Menu, Eline;
- Offner, Fritz;
- Spaargaren, Marcel;
- Moreaux, Jérôme;
- Vanderkerken, Karin;
- Van Valckenborgh, Els;
- De Bruyne, Elke
Publication type:
journal article
Targeted α-Therapy Using <sup>225</sup>Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment.
Published in:
Journal of Nuclear Medicine, 2023, v. 64, n. 5, p. 751, doi. 10.2967/jnumed.122.264752
By:
- Ertveldt, Thomas;
- Krasniqi, Ahmet;
- Ceuppens, Hannelore;
- Puttemans, Janik;
- Dekempeneer, Yana;
- De Jonghe, Kevin;
- de Mey, Wout;
- Lecocq, Quentin;
- De Vlaeminck, Yannick;
- Awad, Robin Maximilian;
- Goyvaerts, Cleo;
- De Veirman, Kim;
- Morgenstern, Alfred;
- Bruchertseifer, Frank;
- Keyaerts, Marleen;
- Devoogdt, Nick;
- D'Huyvetter, Matthias;
- Breckpot, Karine
Publication type:
Article
Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma.
Published in:
Blood Cancer Journal, 2019, v. 9, n. 12, p. 1, doi. 10.1038/s41408-019-0249-x
By:
- Maes, Anke;
- Maes, Ken;
- Vlummens, Philip;
- De Raeve, Hendrik;
- Devin, Julie;
- Szablewski, Vanessa;
- De Veirman, Kim;
- Menu, Eline;
- Moreaux, Jerome;
- Vanderkerken, Karin;
- De Bruyne, Elke
Publication type:
Article
AXL as immune regulator and therapeutic target in Acute Myeloid Leukemia: from current progress to novel strategies.
Published in:
Experimental Hematology & Oncology, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s40164-024-00566-8
By:
- Vandewalle, Niels;
- De Beule, Nathan;
- De Becker, Ann;
- De Bruyne, Elke;
- Menu, Eline;
- Vanderkerken, Karin;
- Breckpot, Karine;
- Devoogdt, Nick;
- De Veirman, Kim
Publication type:
Article
Fueling CARs: metabolic strategies to enhance CAR T-cell therapy.
Published in:
Experimental Hematology & Oncology, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s40164-024-00535-1
By:
- Van der Vreken, Arne;
- Vanderkerken, Karin;
- De Bruyne, Elke;
- De Veirman, Kim;
- Breckpot, Karine;
- Menu, Eline
Publication type:
Article
Metabolic cross-talk within the bone marrow milieu: focus on multiple myeloma.
Published in:
Experimental Hematology & Oncology, 2022, v. 11, n. 1, p. 1, doi. 10.1186/s40164-022-00303-z
By:
- Oudaert, Inge;
- Van der Vreken, Arne;
- Maes, Anke;
- De Bruyne, Elke;
- De Veirman, Kim;
- Vanderkerken, Karin;
- Menu, Eline
Publication type:
Article
Aberrant DNA methylation in multiple myeloma: A major obstacle or an opportunity?
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.979569
By:
- Muylaert, Catharina;
- Van Hemelrijck, Lien Ann;
- Maes, Anke;
- De Veirman, Kim;
- Menu, Eline;
- Vanderkerken, Karin;
- De Bruyne, Elke
Publication type:
Article
Scrutiny of chimeric antigen receptor activation by the extracellular domain: experience with single domain antibodies targeting multiple myeloma cells highlights the need for case-by-case optimization.
Published in:
Frontiers in Immunology, 2024, p. 01, doi. 10.3389/fimmu.2024.1389018
By:
- Hanssens, Heleen;
- Meeus, Fien;
- De Vlaeminck, Yannick;
- Lecocq, Quentin;
- Puttemans, Janik;
- Debie, Pieterjan;
- De Groof, Timo W. M.;
- Goyvaerts, Cleo;
- De Veirman, Kim;
- Breckpot, Karine;
- Devoogdt, Nick
Publication type:
Article
AXL-specific single domain antibodies show diagnostic potential and anti-tumor activity in Acute Myeloid Leukemia.
Published in:
Theranostics, 2024, v. 14, n. 7, p. 2656, doi. 10.7150/thno.91456
By:
- Vandewalle, Niels;
- Satilmis, Hatice;
- Verheye, Emma;
- Rong Fan;
- Yanmeng Wang;
- De Groof, Timo W. M.;
- Bridoux, Jessica;
- Kerre, Tessa;
- De Beule, Nathan;
- De Becker, Ann;
- De Bruyne, Elke;
- Menu, Eline;
- Vanderkerken, Karin;
- Breckpot, Karine;
- Devoogdt, Nick;
- De Veirman, Kim
Publication type:
Article
Pyrroline-5-Carboxylate Reductase 1: a novel target for sensitizing multiple myeloma cells to bortezomib by inhibition of PRAS40-mediated protein synthesis.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02250-3
By:
- Oudaert, Inge;
- Satilmis, Hatice;
- Vlummens, Philip;
- De Brouwer, Wouter;
- Maes, Anke;
- Hose, Dirk;
- De Bruyne, Elke;
- Ghesquière, Bart;
- Vanderkerken, Karin;
- De Veirman, Kim;
- Menu, Eline
Publication type:
Article
Anti-Idiotypic VHHs and VHH-CAR-T Cells to Tackle Multiple Myeloma: Different Applications Call for Different Antigen-Binding Moieties.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 5634, doi. 10.3390/ijms25115634
By:
- Hanssens, Heleen;
- Meeus, Fien;
- Gesquiere, Emma L.;
- Puttemans, Janik;
- De Vlaeminck, Yannick;
- De Veirman, Kim;
- Breckpot, Karine;
- Devoogdt, Nick
Publication type:
Article

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