Works by De Roeck, Arne

Results: 16

NanoSatellite: accurate characterization of expanded tandem repeat length and sequence through whole genome long-read sequencing on PromethION.

Published in:

Genome Biology, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s13059-019-1856-3

By:

De Roeck, Arne;
De Coster, Wouter;
Bossaerts, Liene;
Cacace, Rita;
De Pooter, Tim;
Van Dongen, Jasper;
D'Hert, Svenn;
De Rijk, Peter;
Strazisar, Mojca;
Van Broeckhoven, Christine;
Sleegers, Kristel

Publication type:

Article

Interactive medical and safety monitoring in clinical trials with clinDataReview: a validated and open-source reporting tool.

Published in:

Frontiers in Medicine, 2024, p. 1, doi. 10.3389/fmed.2024.1356323

By:

Cougnaud, Laure;
Faes, Margaux;
Van Krunckelsven, Dirk;
De Roeck, Arne;
Pasetto, Michela;
Fieuw, Ann;
Andersen, Claus A.;
Meyvisch, Paul

Publication type:

Article

CSF biomarker analysis of ABCA7 mutation carriers suggests altered APP processing and reduced inflammatory response.

Published in:

Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01338-y

By:

Duchateau, Lena;
Küҫükali, Fahri;
De Roeck, Arne;
Wittens, Mandy M. J.;
Temmerman, Joke;
Weets, Ilse;
Timmers, Maarten;
Engelborghs, Sebastiaan;
Bjerke, Maria;
Sleegers, Kristel

Publication type:

Article

The role of ABCA7 in Alzheimer's disease: evidence from genomics, transcriptomics and methylomics.

Published in:

Acta Neuropathologica, 2019, v. 138, n. 2, p. 201, doi. 10.1007/s00401-019-01994-1

By:

De Roeck, Arne;
Van Broeckhoven, Christine;
Sleegers, Kristel

Publication type:

Article

Loss of DPP6 in neurodegenerative dementia: a genetic player in the dysfunction of neuronal excitability.

Published in:

Acta Neuropathologica, 2019, v. 137, n. 6, p. 901, doi. 10.1007/s00401-019-01976-3

By:

Cacace, Rita;
Heeman, Bavo;
De Roeck, Arne;
Hoogmartens, Julie;
De Vos, Kristof;
Geerts, Nathalie;
Peeters, Karin;
van der Zee, Julie;
Sleegers, Kristel;
Van Broeckhoven, Christine;
Van Mossevelde, Sara;
Gossye, Helena;
Sieben, Anne;
De Rijk, Peter;
De Coster, Wouter;
Strazisar, Mojca;
De Pooter, Tim;
Vandenberghe, Rik;
C. van Swieten, John;
M. van Duijn, Cornelia

Publication type:

Article

An intronic VNTR affects splicing of ABCA7 and increases risk of Alzheimer’s disease.

Published in:

Acta Neuropathologica, 2018, v. 135, n. 6, p. 827, doi. 10.1007/s00401-018-1841-z

By:

De Roeck, Arne;
Duchateau, Lena;
Van Dongen, Jasper;
Cacace, Rita;
Bjerke, Maria;
Van den Bossche, Tobi;
Cras, Patrick;
Vandenberghe, Rik;
De Deyn, Peter P.;
Engelborghs, Sebastiaan;
Van Broeckhoven, Christine;
Sleegers, Kristel;
On Behalf of the BELNEU Consortium

Publication type:

Article

Amyloid-β<sub>1–43</sub> cerebrospinal fluid levels and the interpretation of APP, PSEN1 and PSEN2 mutations.

Published in:

Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13195-020-00676-5

By:

Perrone, Federica;
Bjerke, Maria;
Hens, Elisabeth;
Sieben, Anne;
Timmers, Maarten;
De Roeck, Arne;
Vandenberghe, Rik;
Sleegers, Kristel;
Martin, Jean-Jacques;
De Deyn, Peter P.;
Engelborghs, Sebastiaan;
van der Zee, Julie;
Van Broeckhoven, Christine;
Cacace, Rita;
on behalf of the BELNEU Consortium;
Goeman, Johan;
Crols, Roeland;
Dermaut, Bart;
Ivanoiu, Adrian;
Hanseeuw, Bernard

Publication type:

Article

Transcript analysis using long‐read sequencing reveals the complex splicing profile of AD‐associated gene ABCA7: Genetics: Genetics and omics of AD I.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042815

By:

Duchateau, Lena;
Küçükali, Fahri;
Van Dongen, Jasper;
Bossaerts, Liene;
Hens, Elisabeth;
De Roeck, Arne;
Mateiu, Ligia;
Van Broeckhoven, Christine;
Sleegers, Kristel

Publication type:

Article

ABCA7 mutations are major contributors to Alzheimer's disease in Belgian patients: Genetics/genetic factors of Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040227

By:

Bossaerts, Liene;
Hens, Elisabeth;
Van den Bossche, Tobi;
De Roeck, Arne;
Engelborghs, Sebastiaan;
Peeters, Karin;
De Deyn, Peter Paul;
Sleegers, Kristel;
Van Broeckhoven, Christine

Publication type:

Article

P4‐093: TOWARDS AN IMPROVED UNDERSTANDING AND ASSESSMENT OF ABCA7 RISK ON ALZHEIMER'S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1310, doi. 10.1016/j.jalz.2019.06.3753

By:

De Roeck, Arne;
Van Broeckhoven, Christine;
Sleegers, Kristel

Publication type:

Article

O4‐01‐01: IN‐DEPTH ANALYSIS OF AN ABCA7 VNTR IN ALZHEIMER'S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1400, doi. 10.1016/j.jalz.2018.06.2909

By:

De Roeck, Arne;
Duchateau, Lena;
Van Dongen, Jasper;
Cacace, Rita;
Bjerke, Maria;
Van den Bossche, Tobi;
Cras, Patrick;
Vandenberghe, Rik;
De Deyn, Peter Paul;
Engelborghs, Sebastiaan;
Van Broeckhoven, Christine;
Sleegers, Kristel

Publication type:

Article

TRANSCRIPTOME ANALYSIS IN BLOOD AND BRAIN IDENTIFIES GENE EXPRESSION REGULATION AND CORRESPONDING QUANTITATIVE TRAIT LOCI IN ALZHEIMER’S DISEASE.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P651, doi. 10.1016/j.jalz.2017.06.766

By:

Verheijen, Jan;
Mateiu, Ligia;
De Roeck, Arne;
Küçükali, Fahri;
Van Dongen, Jasper;
Engelborghs, Sebastiaan;
Vandenbulcke, Mathieu;
Vandenberghe, Rik;
De Deyn, Peter Paul;
Van Broeckhoven, Christine;
Sleegers, Kristel

Publication type:

Article

CONTRIBUTION OF RARE DELETERIOUS ABCA7 MUTATIONS TO A BELGIAN EARLY-ONSET ALZHEIMER’S DISEASE COHORT.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P573, doi. 10.1016/j.jalz.2017.07.191

By:

Van den Bossche, Tobi;
De Roeck, Arne;
Sieben, Anne;
Martin, Jean-Jacques;
Vandenberghe, Rik;
Engelborghs, Sebastiaan;
De Deyn, Peter Paul;
Sleegers, Kristel;
Cras, Patrick;
Van Broeckhoven, Christine

Publication type:

Article

DELETERIOUS ABCA7 MUTATIONS CONTRIBUTE TO EARLY-ONSET ALZHEIMER’S DISEASE AND ARE SUBJECT TO TRANSCRIPT RESCUE MECHANISMS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P589, doi. 10.1016/j.jalz.2017.07.220

By:

De Roeck, Arne;
Van den Bossche, Tobi;
Verheijen, Jan;
De Coster, Wouter;
Van Dongen, Jasper;
Dillen, Lubina;
Baradaran-Heravi, Yalda;
Engelborghs, Sebastiaan;
Cras, Patrick;
van der Zee, Julie;
Van Broeckhoven, Christine;
Sleegers, Kristel

Publication type:

Article

A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ42.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 12, p. 1452, doi. 10.1016/j.jalz.2015.02.013

By:

Sleegers, Kristel;
Bettens, Karolien;
De Roeck, Arne;
Van Cauwenberghe, Caroline;
Cuyvers, Elise;
Verheijen, Jan;
Struyfs, Hanne;
Van Dongen, Jasper;
Vermeulen, Steven;
Engelborghs, Sebastiaan;
Vandenbulcke, Mathieu;
Vandenberghe, Rik;
De Deyn, Peter Paul;
Van Broeckhoven, Christine

Publication type:

Article

The identification of high-penetrant loss-of-function mutations in abca7 in Alzheimer’s disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P854, doi. 10.1016/j.jalz.2015.08.022

By:

Cuyvers, Elise;
De Roeck, Arne;
Van den Bossche, Tobi;
Van Cauwenberghe, Caroline;
Bettens, Karolien;
Vermeulen, Steven;
Mattheijssens, Maria;
Peeters, Karin;
Engelborghs, Sebastiaan;
Vandenbulcke, Mathieu;
Vandenberghe, Rik;
De Deyn, Peter P.;
Van Broeckhoven, Christine;
Sleegers, Kristel

Publication type:

Article