Works by De Meester, Ingrid

Results: 42

Dipeptidyl Peptidase 9 in Human Leukocytes: Novel Inhibitors Induce Caspase‐1‐ and Gasdermin‐Dependent Cell Death.

Published in:

European Journal of Immunology, 2025, v. 55, n. 6, p. 1, doi. 10.1002/eji.202451526

By:

De Loose, Joni;
Mertens, Kathleen;
Filippi, Nicolò;
Corthaut, Sam;
Benramdane, Siham;
Sim, Yani;
Van Rymenant, Yentl;
Claesen, Karen;
Vliegen, Gwendolyn;
Berg, Maya;
Gomard, Tiphanie;
Caljon, Guy;
Pintelon, Isabel;
Van Der Veken, Pieter;
De Meester, Ingrid

Publication type:

Article

Activation of the Carboxypeptidase U (CPU, TAFIa, CPB2) System in Patients with SARS-CoV-2 Infection Could Contribute to COVID-19 Hypofibrinolytic State and Disease Severity Prognosis.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 6, p. 1494, doi. 10.3390/jcm11061494

By:

Claesen, Karen;
Sim, Yani;
Bracke, An;
De bruyn, Michelle;
De Hert, Emilie;
Vliegen, Gwendolyn;
Hotterbeekx, An;
Vujkovic, Alexandra;
van Petersen, Lida;
De Winter, Fien H. R.;
Brosius, Isabel;
Theunissen, Caroline;
van Ierssel, Sabrina;
van Frankenhuijsen, Maartje;
Vlieghe, Erika;
Vercauteren, Koen;
Kumar-Singh, Samir;
De Meester, Ingrid;
Hendriks, Dirk

Publication type:

Article

The Dipeptidyl Peptidases 4, 8, and 9 in Mouse Monocytes and Macrophages: DPP8/9 Inhibition Attenuates M1 Macrophage Activation in Mice.

Published in:

Inflammation, 2016, v. 39, n. 1, p. 413, doi. 10.1007/s10753-015-0263-5

By:

Waumans, Yannick;
Vliegen, Gwendolyn;
Maes, Lynn;
Rombouts, Miche;
Declerck, Ken;
Van Der Veken, Pieter;
Vanden Berghe, Wim;
De Meyer, Guido;
Schrijvers, Dorien;
De Meester, Ingrid

Publication type:

Article

Targeting fibroblast activation protein (FAP): next generation PET radiotracers using squaramide coupled bifunctional DOTA and DATA5m chelators.

Published in:

EJNMMI Radiopharmacy & Chemistry, 2020, v. 5, n. 1, p. 1, doi. 10.1186/s41181-020-00102-z

By:

Moon, Euy Sung;
Elvas, Filipe;
Vliegen, Gwendolyn;
De Lombaerde, Stef;
Vangestel, Christel;
De Bruycker, Sven;
Bracke, An;
Eppard, Elisabeth;
Greifenstein, Lukas;
Klasen, Benedikt;
Kramer, Vasko;
Staelens, Steven;
De Meester, Ingrid;
Van der Veken, Pieter;
Rösch, Frank

Publication type:

Article

Stability, enrichment, and quantification of total and HPV16-specific IgG present in first-void urine.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-65257-0

By:

Téblick, Laura;
Lipovac, Marijana;
Bell, Margo;
De Smet, Annemie;
De Meester, Ingrid;
Delputte, Peter;
Vorsters, Alex

Publication type:

Article

Local Colonic Administration of a Serine Protease Inhibitor Improves Post-Inflammatory Visceral Hypersensitivity in Rats.

Published in:

Pharmaceutics, 2021, v. 13, n. 6, p. 811, doi. 10.3390/pharmaceutics13060811

By:

Hanning, Nikita;
De bruyn, Michelle;
Ceuleers, Hannah;
Boogaerts, Tim;
Berg, Maya;
Smet, Annemieke;
De Schepper, Heiko U.;
Joossens, Jurgen;
van Nuijs, Alexander L. N.;
De Man, Joris G.;
Augustyns, Koen;
De Meester, Ingrid;
De Winter, Benedicte Y.

Publication type:

Article

Dipeptidyl-peptidase IV and B-type natriuretic peptide. From bench to bedside.

Published in:

Clinical Chemistry & Laboratory Medicine, 2009, v. 47, n. 3, p. 248, doi. 10.1515/CCLM.2009.065

By:

Vanderheyden, Marc;
Bartunek, Jozef;
Goethals, Marc;
Verstreken, Sofie;
Lambeir, Anne-Marie;
De Meester, Ingrid;
Scharpé, Simon

Publication type:

Article

Dipeptidyl peptidases and related proteins: multifaceted markers and therapeutic targets.

Published in:

Clinical Chemistry & Laboratory Medicine, 2009, v. 47, n. 3, p. 245, doi. 10.1515/CCLM.2009.085

By:

De Meester, Ingrid;
Scharpé, Simon;
Lambeir, Anne-Marie

Publication type:

Article

Dysregulated activities of proline-specific enzymes in septic shock patients (sepsis-2).

Published in:

PLoS ONE, 2020, v. 15, n. 4, p. 1, doi. 10.1371/journal.pone.0231555

By:

Vliegen, Gwendolyn;
Kehoe, Kaat;
Bracke, An;
De Hert, Emilie;
Verkerk, Robert;
Fransen, Erik;
Jongers, Bart 's;
Peters, Esther;
Lambeir, Anne-Marie;
Kumar-Singh, Samir;
Pickkers, Peter;
Jorens, Philippe G.;
De Meester, Ingrid

Publication type:

Article

Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries.

Published in:

Biological Chemistry, 2011, v. 392, n. 3, p. 189, doi. 10.1515/BC.2011.002

By:

Matheeussen, Veerle;
Baerts, Lesley;
De Meyer, Guido;
De Keulenaer, Gilles;
Van der Veken, Pieter;
Augustyns, Koen;
Dubois, Véronique;
Scharpé, Simon;
De Meester, Ingrid

Publication type:

Article

Peroxynitrite Exposure of CXCL12 Impairs Monocyte, Lymphocyte and Endothelial Cell Chemotaxis, Lymphocyte Extravasation in vivo and Anti-HIV-1 Activity.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01933

By:

Janssens, Rik;
Boff, Daiane;
Ruytinx, Pieter;
Mortier, Anneleen;
Vanheule, Vincent;
Larsen, Olav;
Daugvilaite, Viktorija;
Rosenkilde, Mette M.;
Noppen, Sam;
Liekens, Sandra;
Schols, Dominique;
De Meester, Ingrid;
Opdenakker, Ghislain;
Struyf, Sofie;
Teixeira, Mauro M.;
Amaral, Flávio A.;
Proost, Paul

Publication type:

Article

Left ventricular diastolic dysfunction and myocardial stiffness in diabetic mice is attenuated by inhibition of dipeptidyl peptidase 4.

Published in:

Cardiovascular Research, 2014, v. 104, n. 3, p. 423, doi. 10.1093/cvr/cvu223

By:

Hamdani, Nazha;
Hervent, Anne-Sophie;
Vandekerckhove, Leni;
Matheeussen, Veerle;
Demolder, Marc;
Baerts, Lesley;
De Meester, Ingrid;
Linke, Wolfgang A.;
Paulus, Walter J.;
De Keulenaer, Gilles W.

Publication type:

Article

ProCPU Is Expressed by (Primary) Human Monocytes and Macrophages and Expression Differs between States of Differentiation and Activation.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 4, p. 3725, doi. 10.3390/ijms24043725

By:

Claesen, Karen;
De Loose, Joni;
Van Wielendaele, Pieter;
De bruyn, Emilie;
Sim, Yani;
Thys, Sofie;
De Meester, Ingrid;
Hendriks, Dirk

Publication type:

Article

Prolyl Carboxypeptidase Activity Is Present in Human Adipose Tissue and Is Elevated in Serum of Obese Men with Type 2 Diabetes.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13529, doi. 10.3390/ijms232113529

By:

De Hert, Emilie;
Verboven, Kenneth;
Wouters, Kristiaan;
Jocken, Johan W. E.;
De Meester, Ingrid

Publication type:

Article

Proteolytic Cleavage of Bioactive Peptides and Protease-Activated Receptors in Acute and Post-Colitis.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10711, doi. 10.3390/ijms221910711

By:

De bruyn, Michelle;
Ceuleers, Hannah;
Hanning, Nikita;
Berg, Maya;
De Man, Joris G.;
Hulpiau, Paco;
Hermans, Cedric;
Stenman, Ulf-Håkan;
Koistinen, Hannu;
Lambeir, Anne-Marie;
De Winter, Benedicte Y.;
De Meester, Ingrid

Publication type:

Article

Prolyl Carboxypeptidase Mediates the C-Terminal Cleavage of (Pyr)-Apelin-13 in Human Umbilical Vein and Aortic Endothelial Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 13, p. 6698, doi. 10.3390/ijms22136698

By:

De Hert, Emilie;
Bracke, An;
Pintelon, Isabel;
Janssens, Eline;
Lambeir, Anne-Marie;
Van Der Veken, Pieter;
De Meester, Ingrid

Publication type:

Article

Glycosaminoglycans Regulate CXCR3 Ligands at Distinct Levels: Protection against Processing by Dipeptidyl Peptidase IV/CD26 and Interference with Receptor Signaling.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 7, p. 1513, doi. 10.3390/ijms18071513

By:

Metzemaekers, Mieke;
Mortier, Anneleen;
Janssens, Rik;
Boff, Daiane;
Vanbrabant, Lotte;
Lamoen, Nicole;
Van Damme, Jo;
Teixeira, Mauro M.;
De Meester, Ingrid;
Amaral, Flávio A.;
Proost, Paul

Publication type:

Article

Human Transmembrane Serine Protease 2 (TMPRSS2) on Human Seminal Fluid Extracellular Vesicles Is Proteolytically Active.

Published in:

Journal of Extracellular Vesicles, 2025, v. 14, n. 3, p. 1, doi. 10.1002/jev2.70061

By:

Verhulst, Emile;
De Bruyn, Michelle;
Berckmans, Pascale;
Sim, Yani;
Augustyns, Koen;
Pintelon, Isabel;
Berg, Maya;
Van Wielendaele, Pieter;
Lambeir, Anne‐Marie;
Sterckx, Yann G.‐J.;
Nelissen, Inge;
De Meester, Ingrid

Publication type:

Article

Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post-inflammatory rat model for irritable bowel syndrome.

Published in:

2018

By:

Ceuleers, Hannah;
Hanning, Nikita;
Heirbaut, Jelena;
Van Remoortel, Samuel;
Joossens, Jurgen;
Van Der Veken, Pieter;
Francque, Sven M.;
De bruyn, Michelle;
Lambeir, Anne‐Marie;
De Man, Joris G.;
Timmermans, Jean‐Pierre;
Augustyns, Koen;
De Meester, Ingrid;
De Winter, Benedicte Y.;
Lambeir, Anne-Marie;
Timmermans, Jean-Pierre

Publication type:

journal article

Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0197603

By:

Kehoe, Kaat;
Noels, Heidi;
Theelen, Wendy;
De Hert, Emilie;
Xu, Shenguan;
Verrijken, An;
Arnould, Thierry;
Fransen, Erik;
Hermans, Nina;
Lambeir, Anne-Marie;
Venge, Per;
Van Gaal, Luc;
De Meester, Ingrid

Publication type:

Article

The Effect of Serine Protease Inhibitors on Visceral Pain in Different Rodent Models With an Intestinal Insult.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.765744

By:

Ceuleers, Hannah;
Hanning, Nikita;
De bruyn, Michelle;
De Man, Joris G;
De Schepper, Heiko U;
Li, Qian;
Liu, Liansheng;
Abrams, Steven;
Smet, Annemieke;
Joossens, Jurgen;
Augustyns, Koen;
De Meester, Ingrid;
Pasricha, Pankaj J;
De Winter, Benedicte Y

Publication type:

Article

The Effect of a Novel Serine Protease Inhibitor on Inflammation and Intestinal Permeability in a Murine Colitis Transfer Model.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.682065

By:

Van Spaendonk, Hanne;
Ceuleers, Hannah;
Smet, Annemieke;
Berg, Maya;
Joossens, Jurgen;
Van der Veken, Pieter;
Francque, Sven M.;
Lambeir, Anne-Marie;
De Man, Joris G.;
De Meester, Ingrid;
Augustyns, Koen;
De Winter, Benedicte Y.

Publication type:

Article

Dipeptidyl Peptidase IV-Activated Prodrugs of Anti-Varicella Zoster Virus Bicyclic Nucleoside Analogues Containing Different Self-Cleavage Spacer Systems.

Published in:

ChemMedChem, 2012, v. 7, n. 9, p. 1612, doi. 10.1002/cmdc.201200295

By:

Diez-Torrubia, Alberto;
Cabrera, Silvia;
De Meester, Ingrid;
Camarasa, María-José;
Balzarini, Jan;
Velázquez, Sonsoles

Publication type:

Article

Cover Picture: Dipeptidyl Peptidase IV-Activated Prodrugs of Anti-Varicella Zoster Virus Bicyclic Nucleoside Analogues Containing Different Self-Cleavage Spacer Systems (ChemMedChem 9/2012).

Published in:

ChemMedChem, 2012, v. 7, n. 9, p. 1509, doi. 10.1002/cmdc.201290041

By:

Diez-Torrubia, Alberto;
Cabrera, Silvia;
De Meester, Ingrid;
Camarasa, María-José;
Balzarini, Jan;
Velázquez, Sonsoles

Publication type:

Article

Novel Generation of FAP Inhibitor-Based Homodimers for Improved Application in Radiotheranostics.

Published in:

Cancers, 2023, v. 15, n. 6, p. 1889, doi. 10.3390/cancers15061889

By:

Martin, Marcel;
Ballal, Sanjana;
Yadav, Madhav Prasad;
Bal, Chandrasekhar;
Van Rymenant, Yentl;
De Loose, Joni;
Verhulst, Emile;
De Meester, Ingrid;
Van Der Veken, Pieter;
Roesch, Frank

Publication type:

Article

The Chemokine-Based Peptide, CXCL9(74-103), Inhibits Angiogenesis by Blocking Heparan Sulfate Proteoglycan-Mediated Signaling of Multiple Endothelial Growth Factors.

Published in:

Cancers, 2021, v. 13, n. 20, p. 5090, doi. 10.3390/cancers13205090

By:

De Zutter, Alexandra;
Crijns, Helena;
Berghmans, Nele;
García-Caballero, Melissa;
Vanbrabant, Lotte;
Pörtner, Noëmie;
Vanheule, Vincent;
Verscheure, Paulien;
Siddiquei, Mohammad Mairaj;
Abu El-Asrar, Ahmed M.;
Carmeliet, Peter;
Van Wielendaele, Pieter;
De Meester, Ingrid;
Van Damme, Jo;
Proost, Paul;
Struyf, Sofie

Publication type:

Article

A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-74159-w

By:

Joossen, Cedric;
Baán, Adrienn;
Moreno-Cinos, Carlos;
Joossens, Jurgen;
Cools, Nathalie;
Lanckacker, Ellen;
Moons, Lieve;
Lemmens, Kim;
Lambeir, Anne-Marie;
Fransen, Erik;
Delputte, Peter;
Caljon, Guy;
Van Der Veken, Pieter;
Maes, Louis;
De Meester, Ingrid;
Kiekens, Filip;
Augustyns, Koen;
Cos, Paul

Publication type:

Article

Validated programmed cell death ligand 1 immunohistochemistry assays (E1L3N and SP142) reveal similar immune cell staining patterns in melanoma when using the same sensitive detection system.

Published in:

Histopathology, 2017, v. 70, n. 2, p. 253, doi. 10.1111/his.13056

By:

Schats, Kelly A;
Van Vré, Emily A;
De Schepper, Stefanie;
Boeckx, Carolien;
Schrijvers, Dorien M;
Waelput, Wim;
Fransen, Erik;
Vanden Bempt, Isabelle;
Neyns, Bart;
De Meester, Ingrid;
Kockx, Mark M

Publication type:

Article

Circulating Stromal Cell-Derived Factor 1α Levels in Heart Failure: A Matter of Proper Sampling.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141408

By:

Baerts, Lesley;
Waumans, Yannick;
Brandt, Inger;
Jungraithmayr, Wolfgang;
Van der Veken, Pieter;
Vanderheyden, Marc;
De Meester, Ingrid

Publication type:

Article

Dipeptidyl peptidase IV inhibition improves cardiorenal function in overpacing-induced heart failure.

Published in:

European Journal of Heart Failure, 2012, v. 14, n. 1, p. 14, doi. 10.1093/eurjhf/hfr146

By:

Gomez, Nelson;
Touihri, Karim;
Matheeussen, Veerle;
Mendes Da Costa, Agnès;
Mahmoudabady, Maryam;
Mathieu, Myrielle;
Baerts, Lesley;
Peace, Aaron;
Lybaert, Pascale;
Scharpé, Simon;
De Meester, Ingrid;
Bartunek, Jozef;
Vanderheyden, Marc;
Mc Entee, Kathleen

Publication type:

Article

The CD26/DPP4-inhibitor vildagliptin suppresses lung cancer growth via macrophage-mediated NK cell activity.

Published in:

Carcinogenesis, 2019, v. 40, n. 2, p. 324, doi. 10.1093/carcin/bgz009

By:

Jang, Jae-Hwi;
Janker, Florian;
Meester, Ingrid De;
Arni, Stephan;
Borgeaud, Nathalie;
Yamada, Yoshito;
Bazo, Ignacio Gil;
Weder, Walter;
Jungraithmayr, Wolfgang

Publication type:

Article

An Interdisciplinary Approach Provides Insights into the Pronounced Selectivity of Compound 42 for DPP9.

Published in:

ChemMedChem, 2025, v. 20, n. 5, p. 1, doi. 10.1002/cmdc.202400700

By:

Beyens, Olivier;
Corthaut, Sam;
Lambeir, Anne‐Marie;
Van Der Veken, Pieter;
Sterckx, Yann G.‐J.;
De Meester, Ingrid;
De Winter, Hans

Publication type:

Article

Vildagliptin‐Derived Dipeptidyl Peptidase 9 (DPP9) Inhibitors: Identification of a DPP8/9‐Specific Lead.

Published in:

ChemMedChem, 2022, v. 17, n. 15, p. 1, doi. 10.1002/cmdc.202200097

By:

Benramdane, Siham;
De Loose, Joni;
Beyens, Olivier;
Van Rymenant, Yentl;
Vliegen, Gwendolyn;
Augustyns, Koen;
De Winter, Hans;
De Meester, Ingrid;
Van der Veken, Pieter

Publication type:

Article

ATL>Corrigendum to: Kinetic study of the processing by dipeptidyl-peptidase IV/CD26 of neuropeptides involved in pancreatic insulin secretion (FEBS 25376): [FEBS Letters 507 (2001) 327–330].

Published in:

2002

By:

Lambeir, Anne-Marie;
Durinx, Christine;
Proost, Paul;
Van Damme, Jo;
Scharpé, Simon;
De Meester, Ingrid

Publication type:

Correction Notice

In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA 5.SA.FAPi and DOTA.SA.FAPi.

Published in:

Molecules, 2021, v. 26, n. 12, p. 3482, doi. 10.3390/molecules26123482

By:

Moon, Euy Sung;
Van Rymenant, Yentl;
Battan, Sandeep;
De Loose, Joni;
Bracke, An;
Van der Veken, Pieter;
De Meester, Ingrid;
Rösch, Frank

Publication type:

Article

Natural truncation of RANTES abolishes signaling through the CC chemokine receptors CCR1 and CCR3, impairs its chemotactic potency and generates a CC chemokine inhibitor.

Published in:

European Journal of Immunology, 1998, v. 28, n. 4, p. 1262, doi. 10.1002/(SICI)1521-4141(199804)28:04<1262::AID-IMMU1262>3.0.CO;2-G

By:

Struyf, Sofie;
De Meester, Ingrid;
Scharpé, Simon;
Lenaerts, Jean-Pierre;
Menten, Patricia;
Wang, Ji Ming;
Proost, Paul;
Van Damme, Jo

Publication type:

Article

Binding of adenosine deaminase to the lymphocyte surface via CD26.

Published in:

European Journal of Immunology, 1994, v. 24, n. 3, p. 566, doi. 10.1002/eji.1830240311

By:

De Meester, Ingrid;
Vanham, Guido;
Kestens, Luc;
Vanhoof, Greet;
Bosmans, Eugène;
Gigase, Paul;
Scharpé, Simon

Publication type:

Article

Reference Values for Plasma Dipeptidyl-Peptidase IV Activity and Their Association with Other Laboratory Parameters.

Published in:

Clinical Chemistry & Laboratory Medicine, 2001, v. 39, n. 2, p. 155, doi. 10.1515/cclm.2001.026

By:

Durinx, Christine;
Neels, Hugo;
Van der Auwera, Jean-Claude;
Naelaerts, Kristine;
Scharpé, Simon;
De Meester, Ingrid

Publication type:

Article

Distribution of Prolyl Oligopeptidase in Human Peripheral Tissues and Body Fluids.

Published in:

Clinical Chemistry & Laboratory Medicine, 1996, v. 34, n. 1, p. 17

By:

Goossens, Filip;
De Meester, Ingrid;
Vanhoof, Greet;
Scharpé, Simon

Publication type:

Article

A Sensitive Method for the Assay of Serum Prolyl Endopeptidase.

Published in:

Clinical Chemistry & Laboratory Medicine, 1992, v. 30, n. 4, p. 235

By:

Goossens, F.;
De Meester, Ingrid;
Vanhoof, Greet;
Scharpé, S.

Publication type:

Article

Optimal Evaluation of Programmed Death Ligand-1 on Tumor Cells Versus Immune Cells Requires Different Detection Methods.

Published in:

Archives of Pathology & Laboratory Medicine, 2018, v. 142, n. 8, p. 982, doi. 10.5858/arpa.2017-0159-OA

By:

Schats, Kelly A.;
Van Vré, Emily A.;
Boeckx, Carolien;
De Bie, Martine;
Schrijvers, Dorien M.;
Neyns, Bart;
De Meester, Ingrid;
Kockx, Mark M.

Publication type:

Article

Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV.

Published in:

Critical Reviews in Clinical Laboratory Sciences, 2003, v. 40, n. 3, p. 209, doi. 10.1080/713609354

By:

Lambeir, Anne-Marie;
Durinx, Christine;
Scharpé, Simon;
De Meester, Ingrid

Publication type:

Article