Works by De Lombaerde, Emily

Results: 5
    1

    Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

    Published in:
    Angewandte Chemie International Edition, 2025, v. 64, n. 28, p. 1, doi. 10.1002/anie.202506954
    By:
    • Chen, Yong;
    • De Lombaerde, Emily;
    • Bugler‐Lamb, Aimée;
    • Zhong, Zifu;
    • Schuijs, Martijn J.;
    • Gomez, Claudia M. Brenis;
    • De Baere, Jamie;
    • Gontsarik, Mark;
    • Lauwers, Heleen;
    • Deswarte, Kim;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • Guilliams, Martin;
    • De Geest, Bruno G.
    Publication type:
    Article
    2

    Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202506954
    By:
    • Chen, Yong;
    • De Lombaerde, Emily;
    • Bugler‐Lamb, Aimée;
    • Zhong, Zifu;
    • Schuijs, Martijn J.;
    • Gomez, Claudia M. Brenis;
    • De Baere, Jamie;
    • Gontsarik, Mark;
    • Lauwers, Heleen;
    • Deswarte, Kim;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • Guilliams, Martin;
    • De Geest, Bruno G.
    Publication type:
    Article
    3
    4

    Combinatorial Screening of Biscarbamate Ionizable Lipids Identifies a Low Reactogenicity Lipid for Lipid Nanoparticle mRNA Delivery.

    Published in:
    Advanced Functional Materials, 2024, v. 34, n. 21, p. 1, doi. 10.1002/adfm.202310623
    By:
    • De Lombaerde, Emily;
    • Chen, Yong;
    • Ye, Tingting;
    • Deckers, Julie;
    • Mencarelli, Giulia;
    • De Swarte, Kim;
    • Lauwers, Heleen;
    • De Coen, Ruben;
    • Kasmi, Sabah;
    • Bevers, Sanne;
    • Kuchmiy, Anna;
    • Bogaert, Bram;
    • Baekens, Lies;
    • Zhong, Zifu;
    • Lamoot, Alexander;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • Baptista, Antonio P.;
    • De Koker, Stefaan;
    • De Geest, Bruno G.
    Publication type:
    Article
    5

    Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.

    Published in:
    Small, 2024, p. 1, doi. 10.1002/smll.202306892
    By:
    • Lamoot, Alexander;
    • Jangra, Sonia;
    • Laghlali, Gabriel;
    • Warang, Prajakta;
    • Singh, Gagandeep;
    • Chang, Lauren A.;
    • Park, Seok‐Chan;
    • De Swarte, Kim;
    • Zhong, Zifu;
    • Louage, Benoit;
    • De Lombaerde, Emily;
    • Ye, Tingting;
    • Chen, Yong;
    • Cuadrado‐Castano, Sara;
    • Lienenklaus, Stefan;
    • Sanders, Niek N.;
    • Lambrecht, Bart N.;
    • García‐Sastre, Adolfo;
    • Schotsaert, Michael;
    • De Geest, Bruno G.
    Publication type:
    Article