OpenURL Connection Search

Select item for more details and to access through your institution.

IC‐P‐150: [C‐11]MK‐6884 PET: CHARACTERIZING BRAIN M4 RECEPTORS IN HEALTHY ELDERLY VOLUNTEERS AND ACETYLCHOLINESTERASE INHIBITORS‐TREATED AD PATIENTS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P121, doi. 10.1016/j.jalz.2019.06.4264
By:
- Wang, Yuchuan;
- Li, Wenping;
- Lohith, Talakad G.;
- Bormans, Guy;
- Koole, Michel;
- Van Laere, Koen;
- Serdons, Kim;
- de Hoon, Jan;
- Declercq, Ruben;
- De Lepeleire, Inge;
- Pascual, Maria B.;
- Zanotti-Fregonara, Paolo;
- Yu, Meixiang;
- Arbones, Victoria;
- Masdeu, Joseph C.;
- Cheng, Amy;
- Anderson, Matt S.;
- Hostetler, Eric D.;
- Basile, Anthony S.
Publication type:
Article
IC‐P‐150: [C‐11]MK‐6884 PET: CHARACTERIZING BRAIN M4 RECEPTORS IN HEALTHY ELDERLY VOLUNTEERS AND ACETYLCHOLINESTERASE INHIBITORS‐TREATED AD PATIENTS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P121, doi. 10.1016/j.jalz.2019.06.4264
By:
- Wang, Yuchuan;
- Li, Wenping;
- Lohith, Talakad G.;
- Bormans, Guy;
- Koole, Michel;
- Van Laere, Koen;
- Serdons, Kim;
- de Hoon, Jan;
- Declercq, Ruben;
- De Lepeleire, Inge;
- Pascual, Maria B.;
- Zanotti-Fregonara, Paolo;
- Yu, Meixiang;
- Arbones, Victoria;
- Masdeu, Joseph C.;
- Cheng, Amy;
- Anderson, Matt S.;
- Hostetler, Eric D.;
- Basile, Anthony S.
Publication type:
Article
Preliminary evaluation of the amyloid PET Radioligand [18F]MK-3328 in Alzheimer's Disease patients
Published in:
2011
By:
- Sanabria-Bohorquez, Sandra;
- Hostetler, Eric;
- Van Laere, Koen;
- Koole, Michel;
- Bormans, Guy;
- Serdons, Kim;
- de Hoon, Jan;
- Vandenberghe, Rik;
- Versijpt, Jan;
- De Lepeleire, Inge;
- Reynders, Tom;
- Tamagnan, Gilles;
- Marek, Kenneth;
- Seibyl, John;
- Jennings, Danna;
- Barret, Olivier;
- Koren, Andrei;
- Rosen, Laura;
- Hargreaves, Richard;
- Evelhoch, Jeffrey
Publication type:
Abstract
Development of the amyloid PET radioligand [18F]MK-3328
Published in:
2010
By:
- Sanabria-Bohorquez, Sandra;
- Van Laere, Koen;
- Koole, Michel;
- Bormans, Guy;
- Serdons, Kim;
- de Hoon, Jan;
- Vandenberghe, Rik;
- De Lepeleire, Inge;
- Reynders, Tom;
- Zeng, Zhizhen;
- Williams, David;
- Rosen, Laura;
- Hargreaves, Richard;
- Sur, Cyrille;
- Forman, Mark;
- Hostetler, Eric
Publication type:
Abstract
Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man.
Published in:
Scientific Reports, 2016, p. 27147, doi. 10.1038/srep27147
By:
- Gotter, Anthony L.;
- Forman, Mark S.;
- Harrell, Charles M.;
- Stevens, Joanne;
- Svetnik, Vladimir;
- Yee, Ka Lai;
- Li, Xiaodong;
- Roecker, Anthony J.;
- Fox, Steven V.;
- Tannenbaum, Pamela L.;
- Garson, Susan L.;
- Lepeleire, Inge De;
- Calder, Nicole;
- Rosen, Laura;
- Struyk, Arie;
- Coleman, Paul J.;
- Herring, W. Joseph;
- Renger, John J.;
- Winrow, Christopher J.
Publication type:
Article
Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model*.
Published in:
Clinical Pharmacology & Therapeutics, 1999, v. 65, n. 3, p. 336, doi. 10.1016/S0009-9236(99)70113-X
By:
- Ehrich, Elliot W.;
- Dallob, Aimee;
- De Lepeleire, Inge;
- Van Hecken, Anne;
- Riendeau, Denis;
- Yuan, Weiying;
- Porras, Arturo;
- Wittreich, Johanna;
- Seibold, James R.;
- De Schepper, Paul;
- Mehlisch, Donald R.;
- Gertz, Barry J.
Publication type:
Article
Montelukast causes prolonged, potent leukotriene D4-receptor antagonism in the airways of patients with asthma*.
Published in:
Clinical Pharmacology & Therapeutics, 1997, v. 61, n. 1, p. 83, doi. 10.1016/S0009-9236(97)90184-3
By:
- De Lepeleire, Inge;
- Reiss, Theodore F.;
- Rochette, Felicien;
- Botto, Albert;
- Zhang, Ji;
- Kundu, Sudeep;
- Decramer, Marc
Publication type:
Article
Pharmacokinetics and pharmacodynamics of MK-383, a selective non-peptide platelet glycoprotein-IIb/IIIa receptor antagonist, in healthy men.
Published in:
Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 4, p. 377, doi. 10.1038/clpt.1994.152
By:
- Barrett, Jeffrey S;
- Murphy, Gail;
- Peerlinck, Kathelijne;
- Lepeleire, Inge De;
- Gould, Robert J;
- Panebianco, Deborah;
- Hand, Elizabeth;
- Deckmyn, Hans;
- Vermylen, Jos;
- Arnout, Jef
Publication type:
Article
Pharmacokinetics and pharmacodynamics of multiple oral doses of MK-0591, a 5-lipoxygenase-activating protein inhibitor.
Published in:
Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 1, p. 22, doi. 10.1038/clpt.1994.96
By:
- Depré, Marken;
- Friedman, Beth;
- Van Hecken, Anne;
- De Lepeleire, Inge;
- Tanaka, Wesley;
- Dallob, Aimee;
- Shingo, Sumiko;
- Porras, Arturo;
- Lin, Charles;
- De Schepper, Paul J
Publication type:
Article
Effect of Single Oral Doses of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, on Incretin and Plasma Glucose Levels after an Oral Glucose Tolerance Test in Patients with Type 2 Diabetes.
Published in:
Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 11, p. 4612, doi. 10.1210/jc.2006-1009
By:
- Herman, Gary A.;
- Bergman, Arthur;
- Stevens, Catherine;
- Kotey, Paul;
- Bingming Yi;
- Peng Zhao;
- Dietrich, Bruno;
- Golor, George;
- Schrodter, Andreas;
- Keymeulen, Bart;
- Lasseter, Kenneth C.;
- Kipnes, Mark S.;
- Snyder, Karen;
- Hilliard, Deborah;
- Tanen, Michael;
- Cilissen, Caroline;
- De Smet, Marina;
- de Lepeleire, Inge;
- Van Dyck, Kristien;
- Wang, Amy Q.
Publication type:
Article
Effect of MK-386, a Novel Inhibitor of Type 15~ Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men.
Published in:
Journal of Clinical Endocrinology & Metabolism, 1996, v. 81, n. 8, p. 2942, doi. 10.1210/jc.81.8.2942
By:
- SCHWARTZ, JULES I.;
- VAN HECKEN, ANNE;
- DE SCHEPPER, PAUL J.;
- DE LEPELEIRE, INGE;
- LASSETER, KENNETH C.;
- SHAMBLEN, E. COOPER;
- WINCHELL, GREGORY A.;
- CONSTANZER, MARVIN L.;
- CHAVEZ, CYNTHIA M.;
- WANG, DANIEL Z.;
- EBEL, DAVID L.;
- JUSTICE, STEVEN J.;
- GERTZ, BARRY J.
Publication type:
Article
Characterizing the PK/ PD relationship for inhibition of capsaicin-induced dermal vasodilatation by MK-3207, an oral calcitonin gene related peptide receptor antagonist.
Published in:
British Journal of Clinical Pharmacology, 2015, v. 79, n. 5, p. 831, doi. 10.1111/bcp.12547
By:
- Li, Chi‐Chung;
- Vermeersch, Steve;
- Denney, William S.;
- Kennedy, William P.;
- Palcza, John;
- Gipson, Adrianna;
- Han, Tae H.;
- Blanchard, Rebecca;
- De Lepeleire, Inge;
- Depré, Marleen;
- Murphy, M. Gail;
- Van Dyck, Kristien;
- Hoon, Jan N.
Publication type:
Article
The potent calcitonin gene-related peptide receptor antagonist, telcagepant, does not affect nitroglycerin-induced vasodilation in healthy men.
Published in:
British Journal of Clinical Pharmacology, 2011, v. 71, n. 5, p. 708, doi. 10.1111/j.1365-2125.2010.03869.x
By:
- Van der Schueren, Bart J.;
- Blanchard, Rebecca;
- Murphy, M. Gail;
- Palcza, John;
- De Lepeleire, Inge;
- Van Hecken, Anne;
- Depré, Marleen;
- de Hoon, Jan N.
Publication type:
Article
Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974).
Published in:
British Journal of Clinical Pharmacology, 2010, v. 69, n. 1, p. 15, doi. 10.1111/j.1365-2125.2009.03543.x
By:
- Sinclair, Simon R.;
- Kane, Stefanie A.;
- Van der Schueren, Bart J.;
- Alan Xiao;
- Willson, Kenneth J.;
- Boyle, Janet;
- de Lepeleire, Inge;
- Yang Xu;
- Hickey, Lisa;
- Denney, William S.;
- Chi-Chung Li;
- Palcza, John;
- Vanmolkot, Floris H. M.;
- Depré, Marleen;
- Van Hecken, Anne;
- Murphy, M. Gail;
- Ho, Tony W.;
- de Hoon, Jay N.
Publication type:
Article
Kinetic analysis of the cannabinoid-1 receptor PET tracer [18F]MK-9470 in human brain.
Published in:
European Journal of Nuclear Medicine & Molecular Imaging, 2010, v. 37, n. 5, p. 920, doi. 10.1007/s00259-009-1340-5
By:
- Sanabria-Bohórquez, Sandra Marina;
- Hamill, Terence G.;
- Goffin, Karolien;
- de Lepeleire, Inge;
- Bormans, Guy;
- Burns, H. Donald;
- van Laere, Koen
Publication type:
Article
Quantification, Variability, and Reproducibility of Basal Skeletal Muscle Glucose Uptake in Healthy Humans Using 18F-FDG PET/CT.
Published in:
Journal of Nuclear Medicine, 2015, v. 56, n. 10, p. 1520, doi. 10.2967/jnumed.115.159715
By:
- Gheysens, Olivier;
- Postnov, Andrey;
- Deroose, Christophe M.;
- Vandermeulen, Corinne;
- de Hoon, Jan;
- Declercq, Ruben;
- Dennie, Justin;
- Mixson, Lori;
- De Lepeleire, Inge;
- Van Laere, Koen;
- Klimas, Michael;
- Chakravarthy, Manu V.
Publication type:
Article
11C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists.
Published in:
Journal of Nuclear Medicine, 2014, v. 55, n. 1, p. 65, doi. 10.2967/jnumed.113.122515
By:
- Van Laere, Koenraad J.;
- Sanabria-Bohórquez, Sandra M.;
- Mozley, David P.;
- Burns, Donald H.;
- Hamill, Terence G.;
- Van Hecken, Anne;
- De Lepeleire, Inge;
- Koole, Michel;
- Bormans, Guy;
- de Hoon, Jan;
- Depré, Marleen;
- Cerchio, Kristine;
- Plalcza, John;
- Lingling Han;
- Renger, John;
- Hargreaves, Richard J.;
- Iannone, Robert
Publication type:
Article
Effect of Diltiazem, a Moderate CYP3A Inhibitor, on the Pharmacokinetics of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein Inhibitor, in Healthy Subjects.
Published in:
Journal of Clinical Pharmacology, 2011, v. 51, n. 3, p. 436, doi. 10.1177/0091270010368676
By:
- Garg, Amit;
- Maes, Andrea;
- Corr, Christy;
- Jin, Bo;
- Wadhwa, Tarun;
- Handa, Nikhil;
- Van Dyck, Kristien;
- De Lepeleire, Inge;
- Shah, Jinesh;
- Wagner, John A.;
- Krishna, Rajesh
Publication type:
Article
Lack of Erectogenic Activity of a Novel Selective Melanocortin-4 Receptor Agonist in a Clinical Experimental Model.
Published in:
Journal of Clinical Pharmacology, 2008, v. 48, n. 10, p. 1237, doi. 10.1177/0091270008320925
By:
- Krishna, Rajesh;
- Wong, Peggy;
- Stevens, Catherine;
- de Lepeleire, Inge;
- van Dyck, Kristien;
- Rosen, Raymond C.;
- Gendrano III, Isaias Noel;
- Peeters, Mathieu;
- Wagner, John A.;
- Herman, Gary A.
Publication type:
Article
Multiple-Dose Pharmacokinetics, Pharmacodynamics, and Safety of Taranabant, a Novel Selective Cannabinoid-1 Receptor Inverse Agonist, in Healthy Male Volunteers.
Published in:
Journal of Clinical Pharmacology, 2008, v. 48, n. 6, p. 734, doi. 10.1177/0091270008317591
By:
- Addy, Carol;
- Rothenberg, Paul;
- Susie Li;
- Majumdar, Anup;
- Agrawal, Nancy;
- Hankun Li;
- Ling Zhong;
- Jinyu Yuan;
- Maes, Andrea;
- Dunbar, Stephanie;
- Cote, Josee;
- Rosko, Kim;
- Van Dyck, Kristien;
- De Lepeleire, Inge;
- De Hoon, Jan;
- Van Hecken, Anne;
- Depré, Marleen;
- Knops, Annemie;
- Gottesdiener, Keith;
- Stoch, Aubrey
Publication type:
Article
Pharmacokinetics of Aprepitant After Single and Multiple Oral Doses in Healthy Volunteers.
Published in:
Journal of Clinical Pharmacology, 2006, v. 46, n. 3, p. 291, doi. 10.1177/0091270005283467
By:
- Majumdar, Anup K.;
- Howard, Laura;
- Goldberg, Michael R.;
- Hickey, Lisa;
- Constanzer, Marvin;
- Rothenberg, Paul L.;
- Crumley, Tami M.;
- Panebianco, Deborah;
- Bradstreet, Thomas E.;
- Bergman, Arthur J.;
- Waldman, Scott A.;
- Greenberg, Howard E.;
- Butler, Kathleen;
- Knops, A.;
- De Lepeleire, Inge;
- Michiels, Nicole;
- Petty, Kevin J.
Publication type:
Article
Comparative Inhibitory Activity of Rofecoxib, Meloxicam, Diclofenac, Ibuprofen, and Naproxen on COX-2 versus COX-1 in Healthy Volunteers.
Published in:
Journal of Clinical Pharmacology, 2000, v. 40, n. 10, p. 1109, doi. 10.1177/009127000004001005
By:
- Van Hecken, Anne;
- Schwartz, Jules I.;
- Depré, Marleen;
- De Lepeleire, Inge;
- Dallob, Aimee;
- Tanaka, Wesley;
- Wynants, Kathleen;
- Buntinx, Agnes;
- Arnout, Jef;
- Wong, Peggy H.;
- Ebel, David L.;
- Gertz, Barry J.;
- De Schepper, Paul J.
Publication type:
Article
Effect of Multiple Doses of Montelukast, a CysLT1 Receptor Antagonist, on Digoxin Pharmacokinetics in Healthy Volunteers.
Published in:
Journal of Clinical Pharmacology, 1999, v. 39, n. 9, p. 941, doi. 10.1177/009127009903900908
By:
- Depré, Marleen;
- Van Hecken, Anne;
- Verbesselt, René;
- Wynants, Katleen;
- De Lepeleire, Inge;
- Freeman, Amanda;
- Holland, Sherry;
- Shahane, Aditi;
- Gertz, Barry;
- De Schepper, Paul J.
Publication type:
Article
Effect of Montelukast on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Volunteers.
Published in:
Journal of Clinical Pharmacology, 1999, v. 39, n. 5, p. 495, doi. 10.1177/009127009903900509
By:
- Van Hecken, Anne;
- Depré, Marleen;
- Verbesselt, René;
- Wynants, Kathleen;
- De Lepeleire, Inge;
- Arnout, Jef;
- Wong, Peggy H.;
- Freeman, Amanda;
- Holland, Sherry;
- Gertz, Barry;
- De Schepper, Paul J.
Publication type:
Article
Clinical Evaluation of Brain CB-1 Receptor Occupancy of a Novel CB-1R Inverse Agonist Using CB-1R PET.
Published in:
Diabetes, 2007, v. 56, p. A693
By:
- Addy, Carol;
- Rothenberg, Paul;
- Burns, Donald;
- Sanabria, Sandra;
- Wai-Si Eng;
- De Lepeleire, Inge;
- Dyck, Kristien Van;
- Cote, Josee;
- Rosko, Kim;
- Bormans, Guy;
- De Hoon, Jan;
- Mortelmans, Luc;
- Dupont, Patrick;
- Depre, Marleen;
- Van Hecken, Anne;
- Stoch, Aubrey;
- Gottesdiener, Keith;
- Hargreaves, Richard;
- Wagner, John;
- Van Laere, Koen
Publication type:
Article
Rhinovirus‐16 induced temporal interferon responses in nasal epithelium links with viral clearance and symptoms.
Published in:
Clinical & Experimental Allergy, 2019, v. 49, n. 12, p. 1587, doi. 10.1111/cea.13481
By:
- Ravi, Abilash;
- Chang, Meiping;
- Pol, Marianne;
- Yang, Shan;
- Aliprantis, Antonios;
- Thornton, Bob;
- Carayannopoulos, Leonidas N.;
- Bautmans, An;
- Robberechts, Martine;
- De Lepeleire, Inge;
- Singh, Dave;
- Hohlfeld, Jens M.;
- Sterk, Peter J.;
- Krug, Norbert;
- Lutter, René
Publication type:
Article
Prolonged Oral Treatment with MK-677, a Novel Growth Hormone Secretagogue, Improves Sleep Quality in Man.
Published in:
Neuroendocrinology, 1997, v. 66, n. 4, p. 278, doi. 10.1159/000127249
By:
- Copinschi, Georges;
- Leproult, Rachel;
- Van Onderbergen, Anne;
- Caufriez, Anne;
- Cole, Katrina Y.;
- Schilling, Lisa M.;
- Mendel, Carl M.;
- De Lepeleire, Inge;
- Bolognese, James A.;
- Van Cauter, Eve
Publication type:
Article
Safety, tolerability, and pharmacokinetics of single‐ and multiple‐dose administration of islatravir (MK‐8591) in adults without HIV.
Published in:
CTS: Clinical & Translational Science, 2021, v. 14, n. 5, p. 1935, doi. 10.1111/cts.13048
By:
- Matthews, Randolph P.;
- Ankrom, Wendy;
- Friedman, Evan;
- Jackson Rudd, Deanne;
- Liu, Yang;
- Mogg, Robin;
- Panebianco, Deborah;
- De Lepeleire, Inge;
- Petkova, Magdalena;
- Grobler, Jay A.;
- Stoch, Selwyn Aubrey;
- Iwamoto, Marian
Publication type:
Article
Image-derived input function for [11C]flumazenil kinetic analysis in human brain.
Published in:
2003
By:
- Sanabria-Bohórquez, Sandra M;
- Maes, Alex;
- Dupont, Patrick;
- Bormans, Guy;
- de Groot, Tjibbe;
- Coimbra, Alexandre;
- Eng, WaiSi;
- Laethem, Tine;
- De Lepeleire, Inge;
- Gambale, Jay;
- Vega, Jose M;
- Burns, H Donald
Publication type:
journal article
Image-Derived Input Function for [11C]Flumazenil Kinetic Analysis in Human Brain
Published in:
Molecular Imaging & Biology, 2003, v. 5, n. 2, p. 72, doi. 10.1016/S1536-1632(03)00046-5
By:
- Sanabria-Bohórquez, Sandra M.;
- Maes, Alex;
- Dupont, Patrick;
- Bormans, Guy;
- Groot, Tjibbe de;
- Coimbra, Alexandre;
- Eng, WaiSi;
- Laethem, Tine;
- Lepeleire, Inge De;
- Gambale, Jay;
- Vega, Jose M.;
- Burns, H. Donald
Publication type:
Article
Whole-Body Biodistribution and Radiation Dosimetry of the Human Cannabinoid Type-1 Receptor Ligand 18F-MK-9470 in Healthy Subjects.
Published in:
Journal of Nuclear Medicine, 2008, v. 49, n. 3, p. 439, doi. 10.2967/jnumed.107.047290
By:
- Van Laere, Koen;
- Koole, Michel;
- Bohorquez, Sandra M. Sanabria;
- Goffin, Karolien;
- Guenther, Ilonka;
- Belanger, Marie J.;
- Cote, Josee;
- Rothenberg, Paul;
- De Lepeleire, Inge;
- Grachev, Igor D.;
- Hargreaves, Richard J.;
- Bormans, Guy;
- Burns, H. Donald
Publication type:
Article

Found: 31

IC‐P‐150: [C‐11]MK‐6884 PET: CHARACTERIZING BRAIN M4 RECEPTORS IN HEALTHY ELDERLY VOLUNTEERS AND ACETYLCHOLINESTERASE INHIBITORS‐TREATED AD PATIENTS.

IC‐P‐150: [C‐11]MK‐6884 PET: CHARACTERIZING BRAIN M4 RECEPTORS IN HEALTHY ELDERLY VOLUNTEERS AND ACETYLCHOLINESTERASE INHIBITORS‐TREATED AD PATIENTS.

Preliminary evaluation of the amyloid PET Radioligand [18F]MK-3328 in Alzheimer's Disease patients

Development of the amyloid PET radioligand [<sup>18</sup>F]MK-3328

Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man.

Characterization of rofecoxib as a cyclooxygenase-2 isoform inhibitor and demonstration of analgesia in the dental pain model<sup>*</sup>.

Montelukast causes prolonged, potent leukotriene D<sub>4</sub>-receptor antagonism in the airways of patients with asthma<sup>*</sup>.

Pharmacokinetics and pharmacodynamics of MK-383, a selective non-peptide platelet glycoprotein-IIb/IIIa receptor antagonist, in healthy men.

Pharmacokinetics and pharmacodynamics of multiple oral doses of MK-0591, a 5-lipoxygenase-activating protein inhibitor.

Effect of Single Oral Doses of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, on Incretin and Plasma Glucose Levels after an Oral Glucose Tolerance Test in Patients with Type 2 Diabetes.

Effect of MK-386, a Novel Inhibitor of Type 15~ Reductase, Alone and in Combination with Finasteride, on Serum Dihydrotestosterone Concentrations in Men.

Characterizing the PK/ PD relationship for inhibition of capsaicin-induced dermal vasodilatation by MK-3207, an oral calcitonin gene related peptide receptor antagonist.

The potent calcitonin gene-related peptide receptor antagonist, telcagepant, does not affect nitroglycerin-induced vasodilation in healthy men.

Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974).

Kinetic analysis of the cannabinoid-1 receptor PET tracer [<sup>18</sup>F]MK-9470 in human brain.

Quantification, Variability, and Reproducibility of Basal Skeletal Muscle Glucose Uptake in Healthy Humans Using <sup>18</sup>F-FDG PET/CT.

<sup>11</sup>C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists.

Effect of Diltiazem, a Moderate CYP3A Inhibitor, on the Pharmacokinetics of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein Inhibitor, in Healthy Subjects.

Lack of Erectogenic Activity of a Novel Selective Melanocortin-4 Receptor Agonist in a Clinical Experimental Model.

Multiple-Dose Pharmacokinetics, Pharmacodynamics, and Safety of Taranabant, a Novel Selective Cannabinoid-1 Receptor Inverse Agonist, in Healthy Male Volunteers.

Pharmacokinetics of Aprepitant After Single and Multiple Oral Doses in Healthy Volunteers.

Comparative Inhibitory Activity of Rofecoxib, Meloxicam, Diclofenac, Ibuprofen, and Naproxen on COX-2 versus COX-1 in Healthy Volunteers.

Effect of Multiple Doses of Montelukast, a CysLT1 Receptor Antagonist, on Digoxin Pharmacokinetics in Healthy Volunteers.

Effect of Montelukast on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Volunteers.

Clinical Evaluation of Brain CB-1 Receptor Occupancy of a Novel CB-1R Inverse Agonist Using CB-1R PET.

Rhinovirus‐16 induced temporal interferon responses in nasal epithelium links with viral clearance and symptoms.

Prolonged Oral Treatment with MK-677, a Novel Growth Hormone Secretagogue, Improves Sleep Quality in Man.

Safety, tolerability, and pharmacokinetics of single‐ and multiple‐dose administration of islatravir (MK‐8591) in adults without HIV.

Image-derived input function for [11C]flumazenil kinetic analysis in human brain.

Image-Derived Input Function for [<sup>11</sup>C]Flumazenil Kinetic Analysis in Human Brain

Whole-Body Biodistribution and Radiation Dosimetry of the Human Cannabinoid Type-1 Receptor Ligand <sup>18</sup>F-MK-9470 in Healthy Subjects.