Works by De Geest, Bruno G.

Results: 97

Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 28, p. 1, doi. 10.1002/anie.202506954

By:

Chen, Yong;
De Lombaerde, Emily;
Bugler‐Lamb, Aimée;
Zhong, Zifu;
Schuijs, Martijn J.;
Gomez, Claudia M. Brenis;
De Baere, Jamie;
Gontsarik, Mark;
Lauwers, Heleen;
Deswarte, Kim;
Sanders, Niek N.;
Lambrecht, Bart N.;
Guilliams, Martin;
De Geest, Bruno G.

Publication type:

Article

Thioamides Adjacent to the Ionizable Amine Headgroup in Ionizable Lipids Reduce the pK<sub>a</sub> of Lipid Nanoparticles and Enhance mRNA Transfection Efficiency in Vitro and in Vivo.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202506954

By:

Chen, Yong;
De Lombaerde, Emily;
Bugler‐Lamb, Aimée;
Zhong, Zifu;
Schuijs, Martijn J.;
Gomez, Claudia M. Brenis;
De Baere, Jamie;
Gontsarik, Mark;
Lauwers, Heleen;
Deswarte, Kim;
Sanders, Niek N.;
Lambrecht, Bart N.;
Guilliams, Martin;
De Geest, Bruno G.

Publication type:

Article

Multivalent Antibody‐Recruiting Macromolecules: Linking Increased Binding Affinity with Enhanced Innate Immune Killing.

Published in:

ChemBioChem, 2020, v. 21, n. 21, p. 3036, doi. 10.1002/cbic.202000261

By:

Uvyn, Annemiek;
De Geest, Bruno G.

Publication type:

Article

Surface-Engineered Polyelectrolyte Multilayer Capsules: Synthetic Vaccines Mimicking Microbial Structure and Function.

Published in:

Angewandte Chemie, 2012, v. 124, n. 16, p. 3928, doi. 10.1002/ange.201200048

By:

De Geest, Bruno G.;
Willart, Monique A.;
Lambrecht, Bart N.;
Pollard, Charlotte;
Vervaet, Chris;
Remon, Jean Paul;
Grooten, Johan;
De Koker, Stefaan

Publication type:

Article

Facile Two-Step Synthesis of Porous Antigen-Loaded Degradable Polyelectrolyte Microspheres.

Published in:

Angewandte Chemie, 2010, v. 122, n. 46, p. 8802, doi. 10.1002/ange.201001046

By:

Dierendonck, Marijke;
De Koker, Stefaan;
Cuvelier, Claude;
Grooten, Johan;
Vervaet, Chris;
Remon, Jean-Paul;
De Geest, Bruno G.

Publication type:

Article

Wirkstoffverabreichung mithilfe polymerer Mehrschichtkapseln.

Published in:

Angewandte Chemie, 2010, v. 122, n. 39, p. 7108, doi. 10.1002/ange.200906266

By:

De Cock, Liesbeth J.;
De Koker, Stefaan;
De Geest, Bruno G.;
Grooten, Johan;
Vervaet, Chris;
Remon, Jean Paul;
Sukhorukov, Gleb B.;
Antipina, Maria N.

Publication type:

Article

Tailoring Cellular Uptake of Gold Nanoparticles Via the Hydrophilic-to-Hydrophobic Ratio of their (Co)polymer Coating.

Published in:

Advanced Functional Materials, 2015, v. 25, n. 22, p. 3433, doi. 10.1002/adfm.201500904

By:

Zhang, Zhiyue;
Van Steendam, Katleen;
Maji, Samarendra;
Balcaen, Lieve;
Anoshkina, Yulia;
Zhang, Qilu;
Vanluchene, Glenn;
De Rycke, Riet;
Van Haecke, Frank;
Deforce, Dieter;
Hoogenboom, Richard;
De Geest, Bruno G.

Publication type:

Article

Gold Nanoparticles: Colorimetric Logic Gates Based on Poly(2-alkyl-2-oxazoline)-Coated Gold Nanoparticles (Adv. Funct. Mater. 17/2015).

Published in:

Advanced Functional Materials, 2015, v. 25, n. 17, p. 2627, doi. 10.1002/adfm.201570116

By:

de la Rosa, Victor R.;
Zhang, Zhiyue;
De Geest, Bruno G.;
Hoogenboom, Richard

Publication type:

Article

Colorimetric Logic Gates Based on Poly(2-alkyl-2-oxazoline)-Coated Gold Nanoparticles.

Published in:

Advanced Functional Materials, 2015, v. 25, n. 17, p. 2511, doi. 10.1002/adfm.201404560

By:

de la Rosa, Victor R.;
Zhang, Zhiyue;
De Geest, Bruno G.;
Hoogenboom, Richard

Publication type:

Article

Bio-Hybrid Tumor Cell-Templated Capsules: A Generic Formulation Strategy for Tumor Associated Antigens in View of Immune Therapy.

Published in:

Advanced Functional Materials, 2014, v. 24, n. 45, p. 7139, doi. 10.1002/adfm.201402303

By:

Lybaert, Lien;
De Vlieghere, Elly;
De Rycke, Riet;
Vanparijs, Nane;
De Wever, Olivier;
De Koker, Stefaan;
De Geest, Bruno G.

Publication type:

Article

Nanoporous Hydrogen Bonded Polymeric Microparticles: Facile and Economic Production of Cross Presentation Promoting Vaccine Carriers.

Published in:

Advanced Functional Materials, 2014, v. 24, n. 29, p. 4634, doi. 10.1002/adfm.201400763

By:

Dierendonck, Marijke;
Fierens, Kaat;
De Rycke, Riet;
Lybaert, Lien;
Maji, Samarendra;
Zhang, Zhiyue;
Zhang, Qilu;
Hoogenboom, Richard;
Lambrecht, Bart N.;
Grooten, Johan;
Remon, Jean Paul;
De Koker, Stefaan;
De Geest, Bruno G.

Publication type:

Article

Release Properties of Pressurized Microgel Templated Capsules.

Published in:

Advanced Functional Materials, 2011, v. 21, n. 8, p. 1411, doi. 10.1002/adfm.201002200

By:

Schmidt, Stephan;
Fernandes, Paulo A. L.;
De Geest, Bruno G.;
Delcea, Mihaela;
Skirtach, Andre G.;
Möhwald, Helmuth;
Fery, Andreas

Publication type:

Article

Evaluation of Encoded Layer-By-Layer Coated Microparticles As Protease Sensors.

Published in:

Advanced Functional Materials, 2008, v. 18, n. 11, p. 1624, doi. 10.1002/adfm.200701356

By:

Stubbe, Barbara G.;
Gevaert, Kevin;
Derveaux, Stefaan;
Braeckmans, Kevin;
De Geest, Bruno G.;
Goethals, Marc;
Vandekerckhove, Joel;
Demeester, Joseph;
De Smedt, Stefaan C.

Publication type:

Article

pH-independent immediate release polymethacrylate formulations – an observational study.

Published in:

Drug Development & Industrial Pharmacy, 2016, v. 42, n. 4, p. 578, doi. 10.3109/03639045.2015.1057151

By:

Claeys, Bart;
Vandeputte, Reinout;
De Geest, Bruno G.;
Paul Remon, Jean;
Vervaet, Chris

Publication type:

Article

Gelucire 44/14 based immediate release formulations for poorly water-soluble drugs.

Published in:

Drug Development & Industrial Pharmacy, 2013, v. 39, n. 5, p. 791, doi. 10.3109/03639045.2012.709251

By:

da Fonseca Antunes, André B.;
De Geest, Bruno G.;
Vervaet, Chris;
Remon, Jean Paul

Publication type:

Article

Influenza breakthrough infection in vaccinated mice is characterized by nonpathological lung eosinophilia.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1217181

By:

Chang, Lauren A.;
Choi, Angela;
Rathnasinghe, Raveen;
Warang, Prajakta;
Noureddine, Moataz;
Jangra, Sonia;
Yong Chen;
De Geest, Bruno G.;
Schotsaert, Michael

Publication type:

Article

Towards a Rational Design of Antibody‐Recruiting Molecules through a Computational Microscopy View of their Interactions with the Target Antibody.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 30, p. 1, doi. 10.1002/chem.202300474

By:

Uvyn, Annemiek;
Tonneaux, Corentin;
Fossépré, Mathieu;
Ouvrier‐Buffet, Aude;
De Geest, Bruno G.;
Surin, Mathieu

Publication type:

Article

Visible Light Conjugation with Triazolinediones as a Route to Degradable Poly(ethylene glycol)–Lipids for mRNA Lipid Nanoparticle Formulation.

Published in:

Angewandte Chemie, 2023, v. 135, n. 23, p. 1, doi. 10.1002/ange.202301102

By:

Golba, Bianka;
Soete, Matthieu;
Zhong, Zifu;
Sanders, Niek;
Du Prez, Filip E.;
Houck, Hannes A.;
De Geest, Bruno G.

Publication type:

Article

Tumor‐Selective Activation of Toll‐Like Receptor 7/8 Agonist Nano‐Immunomodulator Generates Safe Anti‐Tumor Immune Responses upon Systemic Administration.

Published in:

Angewandte Chemie, 2022, v. 134, n. 52, p. 1, doi. 10.1002/ange.202214992

By:

Hao, Yanyun;
Li, Hui;
Ge, Xiaoyan;
Liu, Yang;
Li, Xia;
Liu, Yutong;
Chen, Hongfei;
Zhang, Shiying;
Zou, Jing;
Huang, Lingling;
Zhao, Fabao;
Kang, Dongwei;
De Geest, Bruno G.;
Zhang, Zhiyue

Publication type:

Article

Covalent Cell Surface Conjugation of Nanoparticles by a Combination of Metabolic Labeling and Click Chemistry.

Published in:

Angewandte Chemie, 2021, v. 133, n. 12, p. 6390, doi. 10.1002/ange.202015625

By:

Lamoot, Alexander;
Uvyn, Annemiek;
Kasmi, Sabah;
De Geest, Bruno G.

Publication type:

Article

Current Status of COVID‐19 (Pre)Clinical Vaccine Development.

Published in:

Angewandte Chemie, 2020, v. 132, n. 43, p. 19045, doi. 10.1002/ange.202008319

By:

Ye, Tingting;
Zhong, Zifu;
García‐Sastre, Adolfo;
Schotsaert, Michael;
De Geest, Bruno G.

Publication type:

Article

Amphiphile Polymer‐Lipidkonjugate zur potenten lymphatischen Anreicherung von TLR7/8‐Agonisten ermöglichen eine örtlich begrenzte Aktivierung des angeborenen Immunsystems.

Published in:

Angewandte Chemie, 2019, v. 131, n. 43, p. 15535, doi. 10.1002/ange.201905687

By:

De Vrieze, Jana;
Louage, Benoit;
Deswarte, Kim;
Zhong, Zifu;
De Coen, Ruben;
Van Herck, Simon;
Nuhn, Lutz;
Kaas Frich, Camilla;
Zelikin, Alexander N.;
Lienenklaus, Stefan;
Sanders, Niek N.;
Lambrecht, Bart N.;
David, Sunil A.;
De Geest, Bruno G.

Publication type:

Article

Efficient Innate Immune Killing of Cancer Cells Triggered by Cell‐Surface Anchoring of Multivalent Antibody‐Recruiting Polymers.

Published in:

Angewandte Chemie, 2019, v. 131, n. 37, p. 13122, doi. 10.1002/ange.201905093

By:

Uvyn, Annemiek;
De Coen, Ruben;
Gruijs, Mandy;
Tuk, Cees W.;
De Vrieze, Jana;
van Egmond, Marjolein;
De Geest, Bruno G.

Publication type:

Article

Synthetisch hergestellte, transient thermoresponsive Homopolymere mit einer oberen kritischen Lösungstemperatur für physiologisch relevante Anwendungen.

Published in:

Angewandte Chemie, 2019, v. 131, n. 23, p. 7948, doi. 10.1002/ange.201900224

By:

Zhang, Zhiyue;
Li, Hui;
Kasmi, Sabah;
Van Herck, Simon;
Deswarte, Kim;
Lambrecht, Bart N.;
Hoogenboom, Richard;
Nuhn, Lutz;
De Geest, Bruno G.

Publication type:

Article

Förster‐Resonanzenergietransfer‐basierter Nachweis intrazellulärer Ketal‐Hydrolyse in synthetisch vernetzten Nanopartikeln.

Published in:

Angewandte Chemie, 2018, v. 130, n. 33, p. 10920, doi. 10.1002/ange.201803847

By:

Nuhn, Lutz;
Van Herck, Simon;
Best, Andreas;
Deswarte, Kim;
Kokkinopoulou, Maria;
Lieberwirth, Ingo;
Koynov, Kaloian;
Lambrecht, Bart N.;
De Geest, Bruno G.

Publication type:

Article

Self-Exploding Beads Releasing Microcarriers.

Published in:

Advanced Materials, 2008, v. 20, n. 19, p. 3687, doi. 10.1002/adma.200800907

By:

De Geest, Bruno G.;
De Koker, Stefaan;
Immesoete, Kristof;
Demeester, Jo;
De Smedt, Stefaan C.;
Hennink, Wim E.

Publication type:

Article

Next Generation Immunotherapies – Emerging Strategies for Immune Modulation against Cancer, Infections, and Beyond.

Published in:

Advanced Therapeutics, 2021, v. 4, n. 8, p. 1, doi. 10.1002/adtp.202100157

By:

Moon, James J.;
De Geest, Bruno G.;
Sun, Xun

Publication type:

Article

Lipid Nature and Alkyl Length Influence Lymph Node Accumulation of Lipid‐Polyethylene Glycol Amphiphiles.

Published in:

Advanced Therapeutics, 2021, v. 4, n. 8, p. 1, doi. 10.1002/adtp.202100079

By:

De Vrieze, Jana;
Baptista, Antonio P.;
Nuhn, Lutz;
Van Herck, Simon;
Deswarte, Kim;
Yu, Haijun;
Lambrecht, Bart N.;
De Geest, Bruno G.

Publication type:

Article

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment.

Published in:

Biomaterials Research, 2023, v. 27, n. 1, p. 1, doi. 10.1186/s40824-023-00441-3

By:

De Vlieghere, Elly;
Van de Vijver, Koen;
Blondeel, Eva;
Carpentier, Nathan;
Ghobeira, Rouba;
Pauwels, Jarne;
Riemann, Sebastian;
Minsart, Manon;
Fieuws, Charlotte;
Mestach, Johanna;
Baeyens, Ans;
De Geyter, Nathalie;
Debbaut, Charlotte;
Denys, Hannelore;
Descamps, Benedicte;
Claes, Kathleen;
Vral, Anne;
Van Dorpe, Jo;
Gevaert, Kris;
De Geest, Bruno G.

Publication type:

Article

Transient Multivalent Nanobody Targeting to CD206-Expressing Cells via PH-Degradable Nanogels.

Published in:

Cells (2073-4409), 2020, v. 9, n. 10, p. 2222, doi. 10.3390/cells9102222

By:

Scherger, Maximilian;
Bolli, Evangelia;
Antunes, Ana Rita Pombo;
Arnouk, Sana;
Stickdorn, Judith;
Van Driessche, Alexandra;
Schild, Hansjörg;
Grabbe, Stephan;
De Geest, Bruno G.;
Van Ginderachter, Jo A.;
Nuhn, Lutz

Publication type:

Article

Feasibility of Mechanical Extrusion to Coat Nanoparticles with Extracellular Vesicle Membranes.

Published in:

Cells (2073-4409), 2020, v. 9, n. 8, p. 1797, doi. 10.3390/cells9081797

By:

Van Deun, Jan;
Roux, Quentin;
Deville, Sarah;
Van Acker, Thibaut;
Rappu, Pekka;
Miinalainen, Ilkka;
Heino, Jyrki;
Vanhaecke, Frank;
De Geest, Bruno G.;
De Wever, Olivier;
Hendrix, An

Publication type:

Article

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma.

Published in:

2018

By:

Hassannia, Behrouz;
Wiernicki, Bartosz;
Ingold, Irina;
Feng Qu;
Van Herck, Simon;
Tyurina, Yulia Y.;
BayıR, Hülya;
Abhari, Behnaz A.;
Friedmann Angeli, Jose Pedro;
Sze Men Choi;
Meul, Eline;
Heyninck, Karen;
Declerck, Ken;
Chirumamilla, Chandra Sekhar;
Lahtela-Kakkonen, Maija;
Van Camp, Guy;
Krysko, Dmitri V.;
Ekert, Paul G.;
Fulda, Simone;
De Geest, Bruno G.

Publication type:

journal article

Complexity from Simplicity: Unique Polymer Capsules, Rods, Monoliths, and Liquid Marbles Prepared via HIPE in Microfluidics.

Published in:

Particle & Particle Systems Characterization, 2013, v. 30, n. 5, p. 438, doi. 10.1002/ppsc.201200154

By:

Gokmen, M. Talha;
Dereli, Busra;
De Geest, Bruno G.;
Du Prez, Filip E.

Publication type:

Article

Partial Hydrolysis of Poly(2-ethyl-2-oxazoline) and Potential Implications for Biomedical Applications?

Published in:

Macromolecular Bioscience, 2012, v. 12, n. 8, p. 1114, doi. 10.1002/mabi.201200080

By:

Van Kuringen, Huub P. C.;
Lenoir, Joke;
Adriaens, Els;
Bender, Johan;
De Geest, Bruno G.;
Hoogenboom, Richard

Publication type:

Article

Redox-Responsive Degradable PEG Cryogels as Potential Cell Scaffolds in Tissue Engineering.

Published in:

Macromolecular Bioscience, 2012, v. 12, n. 3, p. 383, doi. 10.1002/mabi.201100396

By:

Dispinar, Tugba;
Van Camp, Wim;
De Cock, Liesbeth J.;
De Geest, Bruno G.;
Du Prez, Filip E.

Publication type:

Article

Hydrogen Bonded Multilayer Films Based on Poly(2-oxazoline)s and Tannic Acid.

Published in:

Advanced Healthcare Materials, 2014, v. 3, n. 12, p. 2040, doi. 10.1002/adhm.201400377

By:

Sundaramurthy, Anandhakumar;
Vergaelen, Maarten;
Maji, Samarendra;
Auzély‐Velty, Rachel;
Zhang, Zhiyue;
De Geest, Bruno G.;
Hoogenboom, Richard

Publication type:

Article

Zebrafish Embryos Allow Prediction of Nanoparticle Circulation Times in Mice and Facilitate Quantification of Nanoparticle–Cell Interactions.

Published in:

Small, 2020, v. 16, n. 5, p. N.PAG, doi. 10.1002/smll.201906719

By:

Dal, Nils‐Jørgen Knudsen;
Kocere, Agnese;
Wohlmann, Jens;
Van Herck, Simon;
Bauer, Tobias A.;
Resseguier, Julien;
Bagherifam, Shahla;
Hyldmo, Hilde;
Barz, Matthias;
De Geest, Bruno G.;
Fenaroli, Federico

Publication type:

Article

Surface-Engineered Polyelectrolyte Multilayer Capsules: Synthetic Vaccines Mimicking Microbial Structure and Function.

Published in:

Angewandte Chemie International Edition, 2012, v. 51, n. 16, p. 3862, doi. 10.1002/anie.201200048

By:

De Geest, Bruno G.;
Willart, Monique A.;
Lambrecht, Bart N.;
Pollard, Charlotte;
Vervaet, Chris;
Remon, Jean Paul;
Grooten, Johan;
De Koker, Stefaan

Publication type:

Article

Facile Two-Step Synthesis of Porous Antigen-Loaded Degradable Polyelectrolyte Microspheres.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 46, p. 8620, doi. 10.1002/anie.201001046

By:

Dierendonck, Marijke;
De Koker, Stefaan;
Cuvelier, Claude;
Grooten, Johan;
Vervaet, Chris;
Remon, Jean-Paul;
De Geest, Bruno G.

Publication type:

Article

Polymeric Multilayer Capsules in Drug Delivery.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 39, p. 6954, doi. 10.1002/anie.200906266

By:

De Cock, Liesbeth J.;
De Koker, Stefaan;
De Geest, Bruno G.;
Grooten, Johan;
Vervaet, Chris;
Remon, Jean Paul;
Sukhorukov, Gleb B.;
Antipina, Maria N.

Publication type:

Article

Polyelectrolyte Microcapsules as Antigen Delivery Vehicles To Dendritic Cells: Uptake, Processing, and Cross-Presentation of Encapsulated Antigens.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 45, p. 8485, doi. 10.1002/anie.200903769

By:

De Koker, Stefaan;
De Geest, Bruno G.;
Singh, Satwinder K.;
De Rycke, Riet;
Naessens, Thomas;
Van Kooyk, Yvette;
Demeester, Jo;
De Smedt, Stefaan C.;
Grooten, Johan

Publication type:

Article

Amphiphilic Zwitterionic Bioderived Block Copolymers from Glutamic Acid and Cholesterol – Ability to Form Nanoparticles and Serve as Vectors for the Delivery of 6‐Mercaptopurine.

Published in:

Macromolecular Chemistry & Physics, 2023, v. 224, n. 24, p. 1, doi. 10.1002/macp.202300200

By:

Leiske, Meike N.;
Kuenneth, Christopher;
De Breuck, Jonas;
De Geest, Bruno G.;
Hoogenboom, Richard

Publication type:

Article

Recombinant extracellular vesicles as biological reference material for method development, data normalization and assessment of (pre-)analytical variables.

Published in:

Nature Protocols, 2021, v. 16, n. 2, p. 603, doi. 10.1038/s41596-020-00446-5

By:

Geeurickx, Edward;
Lippens, Lien;
Rappu, Pekka;
De Geest, Bruno G.;
De Wever, Olivier;
Hendrix, An

Publication type:

Article

Visible Light Conjugation with Triazolinediones as a Route to Degradable Poly(ethylene glycol)–Lipids for mRNA Lipid Nanoparticle Formulation.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 23, p. 1, doi. 10.1002/anie.202301102

By:

Golba, Bianka;
Soete, Matthieu;
Zhong, Zifu;
Sanders, Niek;
Du Prez, Filip E.;
Houck, Hannes A.;
De Geest, Bruno G.

Publication type:

Article

Tumor‐Selective Activation of Toll‐Like Receptor 7/8 Agonist Nano‐Immunomodulator Generates Safe Anti‐Tumor Immune Responses upon Systemic Administration.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 52, p. 1, doi. 10.1002/anie.202214992

By:

Hao, Yanyun;
Li, Hui;
Ge, Xiaoyan;
Liu, Yang;
Li, Xia;
Liu, Yutong;
Chen, Hongfei;
Zhang, Shiying;
Zou, Jing;
Huang, Lingling;
Zhao, Fabao;
Kang, Dongwei;
De Geest, Bruno G.;
Zhang, Zhiyue

Publication type:

Article

Covalent Cell Surface Conjugation of Nanoparticles by a Combination of Metabolic Labeling and Click Chemistry.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 12, p. 6320, doi. 10.1002/anie.202015625

By:

Lamoot, Alexander;
Uvyn, Annemiek;
Kasmi, Sabah;
De Geest, Bruno G.

Publication type:

Article

Current Status of COVID‐19 (Pre)Clinical Vaccine Development.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 43, p. 18885, doi. 10.1002/anie.202008319

By:

Ye, Tingting;
Zhong, Zifu;
García‐Sastre, Adolfo;
Schotsaert, Michael;
De Geest, Bruno G.

Publication type:

Article

Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer–Lipid Amphiphile Conjugates of Small‐Molecule TLR7/8 Agonists.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 43, p. 15390, doi. 10.1002/anie.201905687

By:

De Vrieze, Jana;
Louage, Benoit;
Deswarte, Kim;
Zhong, Zifu;
De Coen, Ruben;
Van Herck, Simon;
Nuhn, Lutz;
Kaas Frich, Camilla;
Zelikin, Alexander N.;
Lienenklaus, Stefan;
Sanders, Niek N.;
Lambrecht, Bart N.;
David, Sunil A.;
De Geest, Bruno G.

Publication type:

Article

Efficient Innate Immune Killing of Cancer Cells Triggered by Cell‐Surface Anchoring of Multivalent Antibody‐Recruiting Polymers.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 37, p. 12988, doi. 10.1002/anie.201905093

By:

Uvyn, Annemiek;
De Coen, Ruben;
Gruijs, Mandy;
Tuk, Cees W.;
De Vrieze, Jana;
van Egmond, Marjolein;
De Geest, Bruno G.

Publication type:

Article

A Synthetic, Transiently Thermoresponsive Homopolymer with UCST Behaviour within a Physiologically Relevant Window.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 23, p. 7866, doi. 10.1002/anie.201900224

By:

Zhang, Zhiyue;
Li, Hui;
Kasmi, Sabah;
Van Herck, Simon;
Deswarte, Kim;
Lambrecht, Bart N.;
Hoogenboom, Richard;
Nuhn, Lutz;
De Geest, Bruno G.

Publication type:

Article