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Kinetics of BCR::ABL1 transcript levels and molecular relapse after tyrosine kinase inhibitors discontinuation in chronic myeloid leukemia patients: preliminary results from the DES-CML study.
Published in:
Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1393191
By:
- Murbach, Bruna;
- Duarte, Gislaine;
- Palma, Leonardo Carvalho;
- Miranda, Eliana;
- Duffles, Guilherme;
- Furlin, Graziele Pavan;
- Toni, Isabella;
- De Souza, Carmino;
- Binelli, Larissa;
- Bassan, Vitor Leonardo;
- de Castro, Fabiola Attie;
- de Figueiredo-Pontes, Lorena Lobo;
- Barbosa Pagnano, Katia Borgia
Publication type:
Article
Altered distribution and function of NK-cell subsets lead to impaired tumor surveillance in JAK2V617F myeloproliferative neoplasms.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.768592
By:
- de Oliveira Costa, Amanda Fernandes;
- Marani, Leticia Olops;
- Bianco, Thiago Mantello;
- Arantes, Adriana Queiroz;
- Lopes, Izabela Aparecida;
- Pereira-Martins, Diego Antonio;
- Palma, Leonardo Carvalho;
- Scheucher, Priscila Santos;
- dos Santos Schiavinato, Josiane Lilian;
- Binelli, Larissa Sarri;
- Araújo Silva, Cleide;
- Kobayashi, Susumu S.;
- Agostinho Machado-Neto, João;
- Magalhães Rego, Eduardo;
- Welner, Robert Samuel;
- Lobo de Figueiredo-Pontes, Lorena
Publication type:
Article
Bioactive Lipids as Chronic Myeloid Leukemia's Potential Biomarkers for Disease Progression and Response to Tyrosine Kinase Inhibitors.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.840173
By:
- de Almeida, Felipe Campos;
- Berzoti-Coelho, Maria G.;
- Toro, Diana Mota;
- Cacemiro, Maira da Costa;
- Bassan, Vitor Leonardo;
- Barretto, Gabriel Dessotti;
- Garibaldi, Pedro Manoel Marques;
- Palma, Leonardo Carvalho;
- de Figueiredo-Pontes, Lorena Lobo;
- Sorgi, Carlos Arterio;
- Faciolli, Lucia Helena;
- Gardinassi, Luiz Gustavo;
- de Castro, Fabíola Attié
Publication type:
Article
Ratio of stemness to interferon signalling as a biomarker and therapeutic target of myeloproliferative neoplasm progression to acute myeloid leukaemia.
Published in:
British Journal of Haematology, 2024, v. 204, n. 1, p. 206, doi. 10.1111/bjh.19107
By:
- de Castro, Fabíola Attié;
- Mehdipour, Parinaz;
- Chakravarthy, Ankur;
- Ettayebi, Ilias;
- Loo Yau, Helen;
- Medina, Tiago Silva;
- Marhon, Sajid A.;
- de Almeida, Felipe Campos;
- Bianco, Thiago Mantello;
- Arruda, Andrea G. F.;
- Devlin, Rebecca;
- de Figueiredo‐Pontes, Lorena Lobo;
- Chahud, Fernando;
- da Costa Cacemiro, Maira;
- Minden, Mark D.;
- Gupta, Vikas;
- De Carvalho, Daniel D.
Publication type:
Article
STMN1 is highly expressed and contributes to clonogenicity in acute promyelocytic leukemia cells.
Published in:
Investigational New Drugs, 2022, v. 40, n. 2, p. 438, doi. 10.1007/s10637-021-01197-0
By:
- Vicari, Hugo Passos;
- Coelho-Silva, Juan Luiz;
- Pereira-Martins, Diego A.;
- Lucena-Araujo, Antônio Roberto;
- Lima, Keli;
- Lipreri da Silva, Jean Carlos;
- Scheucher, Priscila Santos;
- Koury, Luisa C.;
- de Melo, Raul A.;
- Bittencourt, Rosane;
- Pagnano, Katia;
- Nunes, Elenaide;
- Fagundes, Evandro M.;
- Kerbauy, Fabio;
- de Figueiredo-Pontes, Lorena Lobo;
- Costa-Lotufo, Leticia Veras;
- Rego, Eduardo Magalhães;
- Traina, Fabiola;
- Machado-Neto, João Agostinho
Publication type:
Article
NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia.
Published in:
Investigational New Drugs, 2021, v. 39, n. 3, p. 736, doi. 10.1007/s10637-020-01028-8
By:
- Scopim-Ribeiro, Renata;
- Machado-Neto, João Agostinho;
- Eide, Christopher A.;
- Coelho-Silva, Juan Luiz;
- Fenerich, Bruna Alves;
- Fernandes, Jaqueline Cristina;
- Scheucher, Priscila Santos;
- Savage Stevens, Samantha L.;
- de Melo Campos, Paula;
- Olalla Saad, Sara T.;
- de Carvalho Palma, Leonardo;
- de Figueiredo-Pontes, Lorena Lobo;
- Simões, Belinda Pinto;
- Rego, Eduardo Magalhães;
- Tognon, Cristina E.;
- Druker, Brian J.;
- Traina, Fabiola
Publication type:
Article
Differential cytokine network profile in polycythemia vera and secondary polycythemia.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63680-7
By:
- Cacemiro, Maira da Costa;
- Cominal, Juçara Gastaldi;
- Berzoti-Coelho, Maria Gabriela;
- Tognon, Raquel;
- Nunes, Natalia de Souza;
- Simões, Belinda;
- Pereira, Ítalo Sousa;
- Carlos, Daniela;
- Faccioli, Lucia Helena;
- Figueiredo-Pontes, Lorena Lobo de;
- Frantz, Fabiani Gai;
- Castro, Fabíola Attié de
Publication type:
Article
Bone Marrow Soluble Mediator Signatures of Patients With Philadelphia Chromosome-Negative Myeloproliferative Neoplasms.
Published in:
Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2021.665037
By:
- Cominal, Juçara Gastaldi;
- Cacemiro, Maira da Costa;
- Berzoti-Coelho, Maria Gabriela;
- Pereira, Illy Enne Gomes;
- Frantz, Fabiani Gai;
- Souto, Elizabeth Xisto;
- Covas, Dimas Tadeu;
- Figueiredo-Pontes, Lorena Lobo de;
- Oliveira, Maria Carolina;
- Malmegrim, Kelen Cristina Ribeiro;
- Castro, Fabíola Attié de
Publication type:
Article
Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPα expression.
Published in:
Science Translational Medicine, 2016, v. 8, n. 350, p. 1, doi. 10.1126/scitranslmed.aad6066
By:
- Kol Jia Yong;
- Basseres, Daniela S.;
- Welner, Robert S.;
- Wen Cai Zhang;
- Henry Yang;
- Benedict Yan;
- Alberich-Jorda, Meritxell;
- Junyan Zhang;
- de Figueiredo-Pontes, Lorena Lobo;
- Battelli, Chiara;
- Hetherington, Christopher J.;
- Min Ye;
- Hong Zhang;
- Maroni, Giorgia;
- O’Brien, Karen;
- Magli, Maria Cristina;
- Borczuk, Alain C.;
- Varticovski, Lyuba;
- Kocher, Olivier;
- Pu Zhang
Publication type:
Article
Metformin exerts multitarget antileukemia activity in JAK2<sup>V617F</sup>-positive myeloproliferative neoplasms.
Published in:
Cell Death & Disease, 2018, v. 9, n. 3, p. 1, doi. 10.1038/s41419-017-0256-4
By:
- Machado-Neto, João Agostinho;
- Fenerich, Bruna Alves;
- Scopim-Ribeiro, Renata;
- Eide, Christopher A.;
- Coelho-Silva, Juan Luiz;
- Dechandt, Carlos Roberto Porto;
- Fernandes, Jaqueline Cristina;
- Rodrigues Alves, Ana Paula Nunes;
- Scheucher, Priscila Santos;
- Simões, Belinda Pinto;
- Alberici, Luciane Carla;
- de Figueiredo Pontes, Lorena Lôbo;
- Tognon, Cristina E.;
- Druker, Brian J.;
- Rego, Eduardo Magalhães;
- Traina, Fabiola
Publication type:
Article
DNMT1-interacting RNAs block gene-specific DNA methylation.
Published in:
Nature, 2013, v. 503, n. 7476, p. 371, doi. 10.1038/nature12598
By:
- Di Ruscio, Annalisa;
- Ebralidze, Alexander K.;
- Benoukraf, Touati;
- Amabile, Giovanni;
- Goff, Loyal A.;
- Terragni, Jolyon;
- Figueroa, Maria Eugenia;
- De Figueiredo Pontes, Lorena Lobo;
- Alberich-Jorda, Meritxell;
- Zhang, Pu;
- Wu, Mengchu;
- D'Alò, Francesco;
- Melnick, Ari;
- Leone, Giuseppe;
- Ebralidze, Konstantin K.;
- Pradhan, Sriharsa;
- Rinn, John L.;
- Tenen, Daniel G.
Publication type:
Article
The co-expression ofPML/RARα andAML1/ETOfusion genes is associated with ATRA resistance.
Published in:
2005
By:
- E Lima, Rodrigo Siqueira Abreu;
- Baruffi, Marcelo Rozera;
- De Lima, Ana Silvia Gouveia;
- De Oliveira, Fábio Morato;
- De Figueiredo-Pontes, Lorena Lôbo;
- Tone, Luiz Gonzaga;
- Rogatto, Sílvia Regina;
- Falcã, Roberto Passetto;
- De Lourdes L. Ferrari Chauffaille, Maria;
- Rego, Eduardo M.
Publication type:
Book Review
Suppression of multiple anti‐apoptotic BCL2 family proteins recapitulates the effects of JAK2 inhibitors in JAK2V617F driven myeloproliferative neoplasms.
Published in:
Cancer Science, 2022, v. 113, n. 2, p. 597, doi. 10.1111/cas.15210
By:
- Takei, Hisashi;
- Coelho‐Silva, Juan Luiz;
- Tavares Leal, Cristina;
- Queiroz Arantes Rocha, Adriana;
- Mantello Bianco, Thiago;
- Welner, Robert S.;
- Mishima, Yuta;
- Kobayashi, Ikei S.;
- Mullally, Ann;
- Lima, Keli;
- Machado‐Neto, João Agostinho;
- Kobayashi, Susumu S.;
- Lobo de Figueiredo‐Pontes, Lorena
Publication type:
Article
Philadelphia-negative myeloproliferative neoplasms display alterations in monocyte subpopulations frequency and immunophenotype.
Published in:
2022
By:
- Bassan, Vitor Leonardo;
- Barretto, Gabriel Dessotti;
- de Almeida, Felipe Campos;
- Palma, Patrícia Vianna Bonini;
- Binelli, Larissa Sarri;
- da Silva, João Paulo Lettieri;
- Fontanari, Caroline;
- Castro, Ricardo Cardoso;
- de Figueiredo Pontes, Lorena Lôbo;
- Frantz, Fabiani Gai;
- de Castro, Fabíola Attié
Publication type:
journal article
Hippo pathway-related genes expression is deregulated in myeloproliferative neoplasms.
Published in:
Medical Oncology, 2022, v. 39, n. 8, p. 1, doi. 10.1007/s12032-022-01696-x
By:
- Cacemiro, Maira da Costa;
- Cominal, Juçara Gastaldi;
- Pereira, Luiz Miguel;
- Berzoti-Coelho, Maria Gabriela;
- Berbel, Giovana Michelassi;
- Baroni, Luciana;
- Malta, Tathiane;
- Tognon, Raquel;
- Nunes, Natalia de Souza;
- Souto, Elizabeth Xisto;
- de Figueiredo-Pontes, Lorena Lobo;
- Yatsuda, Ana Patricia;
- de Castro, Fabíola Attié
Publication type:
Article
Hippo pathway-related genes expression is deregulated in myeloproliferative neoplasms.
Published in:
2022
By:
- Cacemiro, Maira da Costa;
- Cominal, Juçara Gastaldi;
- Pereira, Luiz Miguel;
- Berzoti-Coelho, Maria Gabriela;
- Berbel, Giovana Michelassi;
- Baroni, Luciana;
- Malta, Tathiane;
- Tognon, Raquel;
- Nunes, Natalia de Souza;
- Souto, Elizabeth Xisto;
- de Figueiredo-Pontes, Lorena Lobo;
- Yatsuda, Ana Patricia;
- de Castro, Fabíola Attié
Publication type:
journal article

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