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Type I Hsp40s/DnaJs aggregates exhibit features reminiscent of amyloidogenic structures.
- Published in:
- FEBS Journal, 2024, v. 291, n. 17, p. 3904, doi. 10.1111/febs.17215
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- Publication type:
- Article
Defective regulation of the eIF2-eIF2B translational axis underlies depressive-like behavior in mice and correlates with major depressive disorder in humans.
- Published in:
- Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-03128-y
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- Publication type:
- Article
Brain FNDC5/Irisin Expression in Patients and Mouse Models of Major Depression.
- Published in:
- eNeuro, 2023, v. 10, n. 2, p. 1, doi. 10.1523/ENEURO.0256-22.2023
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- Publication type:
- Article
Acute and chronic neurological consequences of early-life Zika virus infection in mice.
- Published in:
- Science Translational Medicine, 2018, v. 10, n. 444, p. 1, doi. 10.1126/scitranslmed.aar2749
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- Publication type:
- Article
Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease.
- Published in:
- Science Signaling, 2021, v. 14, n. 668, p. 1, doi. 10.1126/scisignal.abc5429
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- Publication type:
- Article
Long-term consequences of the absence of leptin signaling in early life.
- Published in:
- eLife, 2019, p. 1, doi. 10.7554/eLife.40970
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- Publication type:
- Article
Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer's Therapy?
- Published in:
- Frontiers in Aging Neuroscience, 2017, v. 9, p. 1, doi. 10.3389/fnagi.2017.00007
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- Publication type:
- Article
Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer's disease.
- Published in:
- Frontiers in Aging Neuroscience, 2015, v. 7, p. 1, doi. 10.3389/fnagi.2015.00094
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- Publication type:
- Article
Extracellular vesicles derived from human Wharton's jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers.
- Published in:
- Stem Cell Research & Therapy, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13287-019-1432-5
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- Publication type:
- Article
The ketamine metabolite (2R,6R)‐hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5398, doi. 10.1002/alz.14034
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- Publication type:
- Article
Tau ablation in mice leads to pancreatic β cell dysfunction and glucose intolerance.
- Published in:
- FASEB Journal, 2018, v. 32, n. 6, p. 3166, doi. 10.1096/fj.201701352
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- Publication type:
- Article
Amyloid beta oligomers induce impairment of neuronal insulin receptors.
- Published in:
- FASEB Journal, 2008, v. 22, n. 1, p. 246, doi. 10.1096/fj.06-7703com
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- Publication type:
- Article
Neuritogenesis and neuronal differentiation promoted by 2,4-dinitrophenol, a novel anti-amyloidogenic compound.
- Published in:
- FASEB Journal, 2005, v. 19, n. 12, p. 1627, doi. 10.1096/fj.05-3812com
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- Publication type:
- Article
Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Aβ oligomerization.
- Published in:
- FASEB Journal, 2004, v. 18, n. 12, p. 1366, doi. 10.1096/fj.04-1764com
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- Publication type:
- Article
Formation of amyloid aggregates from human lysozyme and its disease-associated variants using hydrostatic pressure.
- Published in:
- FASEB Journal, 2004, v. 18, n. 10, p. 1099, doi. 10.1096/fj.03-1072fje
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- Publication type:
- Article
Neuroprotective Actions of Glucagon-Like Peptide-1 (GLP-1) Analogues in Alzheimer's and Parkinson's Diseases.
- Published in:
- 2019
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- Publication type:
- journal article
Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice.
- Published in:
- Cell Death & Disease, 2019, v. 10, n. 4, p. N.PAG, doi. 10.1038/s41419-019-1529-x
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- Publication type:
- Article
Protective actions of exercise‐related FNDC5/Irisin in memory and Alzheimer's disease.
- Published in:
- Journal of Neurochemistry, 2020, v. 155, n. 6, p. 602, doi. 10.1111/jnc.15039
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- Publication type:
- Article
Insulin Resistance as a Shared Pathogenic Mechanism Between Depression and Type 2 Diabetes.
- Published in:
- Frontiers in Psychiatry, 2019, p. N.PAG, doi. 10.3389/fpsyt.2019.00057
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- Publication type:
- Article
The Role of Leptin and Adiponectin in Obesity-Associated Cognitive Decline and Alzheimer's Disease.
- Published in:
- Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2018.01027
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- Publication type:
- Article
Insulin Resistance in Alzheimer's Disease.
- Published in:
- Frontiers in Neuroscience, 2018, p. N.PAG, doi. 10.3389/fnins.2018.00830
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- Publication type:
- Article
Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects.
- Published in:
- Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00037
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- Publication type:
- Article
Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice.
- Published in:
- Journal of Pathology, 2021, v. 254, n. 3, p. 244, doi. 10.1002/path.5674
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- Publication type:
- Article
The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non‐human primate model of Alzheimer's disease.
- Published in:
- Journal of Pathology, 2018, v. 245, n. 1, p. 85, doi. 10.1002/path.5056
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- Publication type:
- Article
Getting a "GRiP" on Hypothalamic Endoplasmic Reticulum Stress to Combat Obesity.
- Published in:
- 2017
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- Publication type:
- journal article
The emerging neuroprotective roles of exerkines in Alzheimer's disease.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 01, doi. 10.3389/fnagi.2022.965190
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- Publication type:
- Article
Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria.
- Published in:
- PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015230
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- Publication type:
- Article
Brain STAT5 signaling modulates learning and memory formation.
- Published in:
- Brain Structure & Function, 2018, v. 223, n. 5, p. 2229, doi. 10.1007/s00429-018-1627-z
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- Publication type:
- Article
Alzheimer's Disease-Like Pathology Induced by Amyloid-ß Oligomers in Nonhuman Primates.
- Published in:
- Journal of Neuroscience, 2014, v. 34, n. 41, p. 13629, doi. 10.1523/JNEUROSCI.1353-14.2014
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- Publication type:
- Article
Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight Aβ Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 23, p. 9626, doi. 10.1523/JNEUROSCI.0482-13.2013
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- Publication type:
- Article
Correction of mTORC1‐mediated brain protein synthesis rescues memory in mouse models of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074211
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- Publication type:
- Article
Synaptic proteasome is inhibited in Alzheimer's disease models and is associated with memory impairment in mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072107
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- Publication type:
- Article
Alzheimer's disease brain‐derived extracellular vesicles reveal altered synapse‐related proteome and induce cognitive impairment in mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5418, doi. 10.1002/alz.13134
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- Publication type:
- Article
Epigenetic modulation of cognitive function: toward new treatment models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.064971
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- Publication type:
- Article
FNDC5/irisin expression stimulates neuroprotective pathways in hippocampal neurons and associates with Alzheimer's disease pathology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.063439
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- Publication type:
- Article
Cerebrospinal fluid irisin and lipoxin A4 are reduced in elderly Brazilian individuals with depression: Insight into shared mechanisms between depression and dementia.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 6, p. 2595, doi. 10.1002/alz.12893
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- Publication type:
- Article
Attenuation of translational repression rescues memory impairment in Alzheimer's disease mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.059761
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- Publication type:
- Article
Ubiquitin‐proteasome system dysfunction induced by Alzheimer's disease‐linked Ab oligomers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.061094
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- Publication type:
- Article
Aβ oligomers impair neuronal insulin signaling
- Published in:
- 2010
- By:
- Publication type:
- Abstract
P4-263: Insulin prevents the pathological impact of soluble Abeta oligomers on neuronal insulin receptors
- Published in:
- 2008
- By:
- Publication type:
- Abstract
Structural changes in the obese brain.
- Published in:
- Neural Regeneration Research, 2024, v. 19, n. 12, p. 2561, doi. 10.4103/NRR.NRR-D-23-01123
- By:
- Publication type:
- Article
The Link Between Tau and Insulin Signaling: Implications for Alzheimer's Disease and Other Tauopathies.
- Published in:
- Frontiers in Cellular Neuroscience, 2019, p. N.PAG, doi. 10.3389/fncel.2019.00017
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- Publication type:
- Article
Potentials and Pitfalls of Cross-Translational Models of Cognitive Impairment.
- Published in:
- Frontiers in Behavioral Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnbeh.2019.00048
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- Publication type:
- Article
Leptin receptor reactivation restores brain function in early-life Lepr-deficient mice.
- Published in:
- Brain: A Journal of Neurology, 2024, v. 147, n. 8, p. 2706, doi. 10.1093/brain/awae127
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- Publication type:
- Article
Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model.
- Published in:
- Journal of Neuroscience, 2017, v. 37, n. 28, p. 6797, doi. 10.1523/JNEUROSCI.3351-16.2017
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- Publication type:
- Article
Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice.
- Published in:
- Journal of Neuroscience, 2016, v. 36, n. 48, p. 12106, doi. 10.1523/JNEUROSCI.1269-16.2016
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- Publication type:
- Article
A Key Role of Insulin Receptors in Memory.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease.
- Published in:
- Diabetes, 2014, v. 63, n. 7, p. 2262, doi. 10.2337/db13-1954
- By:
- Publication type:
- Article
Lung inflammation induced by silica particles triggers hippocampal inflammation, synapse damage and memory impairment in mice.
- Published in:
- Journal of Neuroinflammation, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12974-022-02662-0
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- Publication type:
- Article
Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers.
- Published in:
- 2021
- By:
- Publication type:
- journal article