Works by De Deurwaerdere, Philippe

Results: 67

Updating neuropathology and neuropharmacology of monoaminergic systems.

Published in:

2016

By:

Ramsay, Rona R;
De Deurwaerdère, Philippe;
Di Giovanni, Giuseppe;
De Deurwaerdère, Philippe

Publication type:

Editorial

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep03730

By:

Qin Li;
Bezard, Erwan;
Porras, Gregory;
Marti, Matteo;
Morari, Michele;
De Deurwaerdere, Philippe;
Sohr, Reinhard;
Morgenstern, Rudolf;
Meissner, Wassilios G.

Publication type:

Article

Alteration of nociceptive integration in the spinal cord of a rat model of Parkinson's disease.

Published in:

2018

By:

Charles, Keri‐Ann;
Naudet, Frédéric;
Bouali‐Benazzouz, Rabia;
Landry, Marc;
De Deurwaerdère, Philippe;
Fossat, Pascal;
Benazzouz, Abdelhamid;
Charles, Keri-Ann;
Bouali-Benazzouz, Rabia

Publication type:

journal article

Editorial: New GPCR targets and modulators to treat CNS disorders.

Published in:

Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.1104336

By:

De Deurwaerdère, Philippe;
Ponimaskin, Evgeni;
Chagraoui, Abdeslam;
Di Giovanni, Giuseppe

Publication type:

Article

Constitutive Activity of the Serotonin2C Receptor Inhibits In Vivo Dopamine Release in the Rat Striatum and Nucleus Accumbens.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 13, p. 3235, doi. 10.1523/JNEUROSCI.0112-04.2004

By:

De Deurwaerdère, Philippe;
Navailles, Sylvia;
Berg, Kelly A.;
Clarke, William P.;
Spampinato, Umberto

Publication type:

Article

Brief early-life motor training induces behavioral changes and alters neuromuscular development in mice.

Published in:

PLoS Biology, 2025, v. 23, n. 4, p. 1, doi. 10.1371/journal.pbio.3003153

By:

Quilgars, Camille;
Boué-Grabot, Eric;
de Deurwaerdère, Philippe;
Cazalets, Jean-René;
Perrin, Florence E.;
Bertrand, Sandrine S.

Publication type:

Article

8-OH-DPAT, a 5-HT[sub 1A] agonist and ritanserin, a 5-HT[sub 2A/C] antagonist, reverse haloperidol-induced catalepsy in rats independently of striatal dopamine release.

Published in:

Psychopharmacology, 1997, v. 131, n. 1, p. 57, doi. 10.1007/s002130050265

By:

Lucas, Guillaume;
Bonhomme, Norbert;
Deurwaerdère, Philippe De;
Moal, Michel Le;
Spampinato, U.

Publication type:

Article

Deleting Snord115 genes in mice remodels monoaminergic systems activity in the brain toward cortico-subcortical imbalances.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 2, p. 244, doi. 10.1093/hmg/ddac139

By:

Marty, Virginie;
Butler, Jasmine J;
Coutens, Basile;
Chargui, Oumaima;
Chagraoui, Abdeslam;
Guiard, Bruno P;
Deurwaerdère, Philippe De;
Cavaillé, Jérôme

Publication type:

Article

Limiting Monoamines Degradation Increases L-DOPA Pro-Locomotor Action in Newborn Rats.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14747, doi. 10.3390/ijms241914747

By:

Khsime, Inès;
Boulain, Marie;
Fettah, Abderrahman;
Chagraoui, Abdeslam;
Courtand, Gilles;
De Deurwaerdère, Philippe;
Juvin, Laurent;
Barrière, Grégory

Publication type:

Article

Pathophysiology of the Serotonin System in the Nervous System and Beyond.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4712, doi. 10.3390/ijms23094712

By:

De Deurwaerdère, Philippe;
Di Giovanni, Giuseppe

Publication type:

Article

Simulated Microgravity Subtlety Changes Monoamine Function across the Rat Brain.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11759, doi. 10.3390/ijms222111759

By:

Gros, Alexandra;
Lavenu, Léandre;
Morel, Jean-Luc;
De Deurwaerdère, Philippe

Publication type:

Article

Beneficial Effects of Metformin on the Central Nervous System, with a Focus on Epilepsy and Lafora Disease.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5351, doi. 10.3390/ijms22105351

By:

Sanz, Pascual;
Serratosa, José Maria;
Sánchez, Marina P.;
Deurwaerdère, Philippe De

Publication type:

Article

BDNF Overexpression in the Ventral Hippocampus Promotes Antidepressant- and Anxiolytic-Like Activity in Serotonin Transporter Knockout Rats.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 5040, doi. 10.3390/ijms22095040

By:

Diniz, Danielle M.;
Calabrese, Francesca;
Brivio, Paola;
Riva, Marco A.;
Grandjean, Joanes;
Homberg, Judith R.;
De Deurwaerdere, Philippe;
Di Giovanni, Giuseppe

Publication type:

Article

Effective Drug Concentration and Selectivity Depends on Fraction of Primitive Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4931, doi. 10.3390/ijms22094931

By:

Lica, Jan Jakub;
Wieczór, Miłosz;
Grabe, Grzegorz Jan;
Heldt, Mateusz;
Jancz, Marta;
Misiak, Majus;
Gucwa, Katarzyna;
Brankiewicz, Wioletta;
Maciejewska, Natalia;
Stupak, Anna;
Bagiński, Maciej;
Rolka, Krzysztof;
Hellmann, Andrzej;
Składanowski, Andrzej;
Deurwaerdère, Philippe De

Publication type:

Article

Lateral Habenula 5-HT 2C Receptor Function Is Altered by Acute and Chronic Nicotine Exposures.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4775, doi. 10.3390/ijms22094775

By:

Bombardi, Cristiano;
Delicata, Francis;
Tagliavia, Claudio;
Grandis, Annamaria;
Pierucci, Massimo;
Marino Gammazza, Antonella;
Casarrubea, Maurizio;
De Deurwaerdère, Philippe;
Di Giovanni, Giuseppe;
Nakamaru-Ogiso, Eiko

Publication type:

Article

iPSCs: A Preclinical Drug Research Tool for Neurological Disorders.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4596, doi. 10.3390/ijms22094596

By:

Bonaventura, Gabriele;
Iemmolo, Rosario;
Attaguile, Giuseppe Antonino;
La Cognata, Valentina;
Pistone, Brigida Sabrina;
Raudino, Giuseppe;
D'Agata, Velia;
Cantarella, Giuseppina;
Barcellona, Maria Luisa;
Cavallaro, Sebastiano;
Fedele, Ernesto;
Deurwaerdère, Philippe De;
Ofir, Rivka

Publication type:

Article

Cannabidiol in Neurological and Neoplastic Diseases: Latest Developments on the Molecular Mechanism of Action.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4294, doi. 10.3390/ijms22094294

By:

Ożarowski, Marcin;
Karpiński, Tomasz M.;
Zielińska, Aleksandra;
Souto, Eliana B.;
Wielgus, Karolina;
De Deurwaerdère, Philippe

Publication type:

Article

Prolyl Oligopeptidase Regulates Dopamine Transporter Oligomerization and Phosphorylation in a PKC- and ERK-Independent Manner.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1777, doi. 10.3390/ijms22041777

By:

Julku, Ulrika H.;
Jäntti, Maria;
Svarcbahs, Reinis;
Myöhänen, Timo T.;
Deurwaerdère, Philippe De

Publication type:

Article

A Subset of Purposeless Oral Movements Triggered by Dopaminergic Agonists Is Modulated by 5-HT 2C Receptors in Rats: Implication of the Subthalamic Nucleus.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8509, doi. 10.3390/ijms21228509

By:

Lagière, Mélanie;
Bosc, Marion;
Whitestone, Sara;
Benazzouz, Abdelhamid;
Chagraoui, Abdeslam;
Millan, Mark J.;
De Deurwaerdère, Philippe

Publication type:

Article

Chronic Administration of Fipronil Heterogeneously Alters the Neurochemistry of Monoaminergic Systems in the Rat Brain.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5711, doi. 10.3390/ijms21165711

By:

Bharatiya, Rahul;
Chagraoui, Abdeslam;
De Deurwaerdere, Salomé;
Argiolas, Antonio;
Melis, Maria Rosaria;
Sanna, Fabrizio;
De Deurwaerdere, Philippe

Publication type:

Article

Serotonin in Health and Disease.

Published in:

2020

By:

De Deurwaerdère, Philippe;
Di Giovanni, Giuseppe

Publication type:

Editorial

Acute and Chronic Nicotine Exposures Differentially Affect Central Serotonin 2A Receptor Function: Focus on the Lateral Habenula.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 5, p. 1873, doi. 10.3390/ijms21051873

By:

Bombardi, Cristiano;
Delicata, Francis;
Tagliavia, Claudio;
Pierucci, Massimo;
Deidda, Gabriele;
Casarrubea, Maurizio;
De Deurwaerdère, Philippe;
Di Giovanni, Giuseppe

Publication type:

Article

Serotonin in Animal Cognition and Behavior.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 5, p. 1649, doi. 10.3390/ijms21051649

By:

Bacqué-Cazenave, Julien;
Bharatiya, Rahul;
Barrière, Grégory;
Delbecque, Jean-Paul;
Bouguiyoud, Nouhaila;
Di Giovanni, Giuseppe;
Cattaert, Daniel;
De Deurwaerdère, Philippe

Publication type:

Article

L-DOPA in Parkinson's Disease: Looking at the "False" Neurotransmitters and Their Meaning.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 1, p. 294, doi. 10.3390/ijms21010294

By:

Chagraoui, Abdeslam;
Boulain, Marie;
Juvin, Laurent;
Anouar, Youssef;
Barrière, Grégory;
De Deurwaerdère, Philippe

Publication type:

Article

Effect of the 5-HT2C Receptor Agonist WAY-163909 on Serotonin and Dopamine Metabolism across the Rat Brain: A Quantitative and Qualitative Neurochemical Study.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 12, p. 2925, doi. 10.3390/ijms20122925

By:

Whitestone, Sara;
De Deurwaerdère, Philippe;
Baassiri, Lynn;
Manem, Julien;
Anouar, Youssef;
Di Giovanni, Giuseppe;
Bharatiya, Rahul;
Chagraoui, Abdeslam

Publication type:

Article

Serotonergic neurons are involved in the counter‐regulatory response to hypoglycemia.

Published in:

Journal of Neuroendocrinology, 2023, v. 35, n. 12, p. 1, doi. 10.1111/jne.13344

By:

Martin, Hugo;
Coursan, Adeline;
Lallement, Justine;
Di Miceli, Mathieu;
Kandiah, Janany;
Raho, Ilyès;
Buttler, Jasmine;
Guilloux, Jean‐Philippe;
De Deurwaerdere, Philippe;
Layé, Sophie;
Routh, Vanessa H.;
Guiard, Bruno P.;
Magnan, Christophe;
Cruciani‐Guglielmacci, Céline;
Fioramonti, Xavier

Publication type:

Article

Editorial: Non-Dopaminergic Systems in Parkinson's Disease.

Published in:

2020

By:

Miguelez, Cristina;
De Deurwaerdère, Philippe;
Sgambato, Véronique

Publication type:

Editorial

Lorcaserin Alters Serotonin and Noradrenaline Tissue Content and Their Interaction With Dopamine in the Rat Brain.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00962

By:

Di Giovanni, Giuseppe;
Bharatiya, Rahul;
Puginier, Emilie;
Ramos, Marta;
De Deurwaerdère, Salomé;
Chagraoui, Abdeslam;
De Deurwaerdère, Philippe

Publication type:

Article

Conditional involvement of striatal serotonin3 receptors in the control of in vivo dopamine outflow in the rat striatum.

Published in:

European Journal of Neuroscience, 2003, v. 17, n. 4, p. 771, doi. 10.1046/j.1460-9568.2003.02512.x

By:

Porras, Grégory;
De Deurwaerdère, Philippe;
Moison, Delphine;
Spampinato, Umberto

Publication type:

Article

Neurochemical and electrophysiological evidence that 5-HT4 receptors exert a state-dependent facilitatory control in vivo on nigrostriatal, but not mesoaccumbal, dopaminergic function.

Published in:

European Journal of Neuroscience, 2001, v. 13, n. 5, p. 889, doi. 10.1046/j.0953-816X.2000.01453.x

By:

Lucas, Guillaume;
Di Matteo, Vincenzo;
De Deurwaerdère, Philippe;
Porras, Grégory;
Martín‐Ruiz, Raúl;
Artigas, Francesc;
Esposito, Ennio;
Spampinato, Umberto

Publication type:

Article

Lead-Induced Atypical Parkinsonism in Rats: Behavioral, Electrophysiological, and Neurochemical Evidence for a Role of Noradrenaline Depletion.

Published in:

Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00173

By:

Sabbar, Mariam;
Delaville, Claire;
De Deurwaerdère, Philippe;
Lakhdar-Ghazal, Nouria;
Benazzouz, Abdelhamid

Publication type:

Article

High-Frequency Stimulation of the Subthalamic Nucleus and L-3,4-Dihydroxyphenylalanine Inhibit In Vivo Serotonin Release in the Prefrontal Cortex and Hippocampus in a Rat Model of Parkinson's Disease.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 6, p. 2356, doi. 10.1523/JNEUROSCI.5031-09.2010

By:

Navailles, Sylvia;
Benazzouz, Abdelhamid;
Bioulac, Bernard;
Gross, Christian;
De Deurwaerdère, Philippe

Publication type:

Article

Brainstem serotonin amplifies nociceptive transmission in a mouse model of Parkinson's disease.

Published in:

NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-024-00857-1

By:

Grivet, Zoé;
Aby, Franck;
Verboven, Aude;
Bouali-Benazzouz, Rabia;
Sueur, Benjamin;
Maingret, François;
Naudet, Frédéric;
Dhellemmes, Thibault;
De Deurwaerdere, Philippe;
Benazzouz, Abdelhamid;
Fossat, Pascal

Publication type:

Article

Monoaminergic and Histaminergic Strategies and Treatments in Brain Diseases.

Published in:

Frontiers in Neuroscience, 2016, v. 10, p. 1, doi. 10.3389/fnins.2016.00541

By:

Di Giovanni, Giuseppe;
Strac, Dubravka Svob;
Sole, Montse;
Unzeta, Mercedes;
Tipton, Keith F.;
Mück-šeler, Dorotea;
Bolea, Irene;
Corte, Laura Della;
Perkovic, Matea Nikolac;
Pivac, Nela;
Smolders, Ilse J.;
Stasiak, Anna;
Fogel, Wieslawa A.;
Deurwaerdère, Philippe De

Publication type:

Article

Monoaminergic Mechanisms in Epilepsy May Offer Innovative Therapeutic Opportunity for Monoaminergic Multi-Target Drugs.

Published in:

Frontiers in Neuroscience, 2016, v. 10, p. 1, doi. 10.3389/fnins.2016.00492

By:

Strac, Dubravka Svob;
Pivac, Nela;
Smolders, Ilse J.;
Fogel, Wieslawa A.;
De Deurwaerdere, Philippe;
Di Giovanni, d. Giuseppe

Publication type:

Article

Early Prenatal Exposure to MPTP Does Not Affect Nigrostrial Neurons in Macaque Monkey.

Published in:

Synapse, 2016, v. 70, n. 2, p. 52, doi. 10.1002/syn.21876

By:

BOURDENX, MATHIEU;
DOVERO, SANDRA;
DE DEURWAERDÈRE, PHILIPPE;
QIN LI;
BEZARD, ERWAN

Publication type:

Article

Old neurochemical markers, new functional directions?: An Editorial for 'Distinct gradients of various neurotransmitter markers in caudate nucleus and putamen of the human brain' on page 650.

Published in:

Journal of Neurochemistry, 2020, v. 152, n. 6, p. 623, doi. 10.1111/jnc.14929

By:

De Deurwaerdere, Philippe;
Gaetani, Silvana;
Vaughan, Roxanne A.

Publication type:

Article

Serotonin2c ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease.

Published in:

International Journal of Neuropsychopharmacology, 2013, v. 16, n. 3, p. 593, doi. 10.1017/S1461145712000417

By:

Navailles, Sylvia;
Lagière, Melanie;
Roumegous, Audrey;
Polito, Marina;
Boujema, Méric B.;
Cador, Martine;
Dunlop, John;
Chesselet, Marie-Françoise;
Millan, Mark J.;
Deurwaerdère, Philippe De

Publication type:

Article

L‐DOPA and 5‐HTP modulation of air‐stepping in newborn rats.

Published in:

Journal of Physiology, 2021, v. 599, n. 19, p. 4455, doi. 10.1113/JP281983

By:

Boulain, Marie;
Yuan, Wei;
Oueghlani, Zied;
Khsime, Inès;
Salvi, Vianney;
Courtand, Gilles;
Halgand, Christophe;
Morin, Didier;
de Deurwaerdere, Philippe;
Barrière, Grégory;
Juvin, Laurent

Publication type:

Article

Neurobiological and Pharmacological Perspectives of D3 Receptors in Parkinson's Disease.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 2, p. 243, doi. 10.3390/biom12020243

By:

Chagraoui, Abdeslam;
Di Giovanni, Giuseppe;
De Deurwaerdère, Philippe

Publication type:

Article

Dopamine D3 Receptor: Contemporary Views of Its Function and Pharmacology for Neuropsychiatric Diseases.

Published in:

2021

By:

De Deurwaerdère, Philippe;
Chagraoui, Abdeslam

Publication type:

Editorial

Widespread Monoaminergic Dysregulation of Both Motor and Non-Motor Circuits in Parkinsonism and Dyskinesia.

Published in:

Cerebral Cortex, 2015, v. 25, n. 9, p. 2783, doi. 10.1093/cercor/bhu076

By:

Engeln, Michel;
De Deurwaerdère, Philippe;
Qin Li;
Bezard, Erwan;
Fernagut, Pierre-Olivier

Publication type:

Article

Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia.

Published in:

2012

By:

Navailles, Sylvia;
Deurwaerdère, Philippe De

Publication type:

Journal Article

Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia.

Published in:

Parkinson's Disease (20420080), 2012, p. 1, doi. 10.1155/2012/323686

By:

Navailles, Sylvia;
Deurwaerdère, Philippe De

Publication type:

Article

Role of Serotonin2A and Serotonin2B/2C Receptor Subtypes in the Control of Accumbal and Striatal Dopamine Release Elicited In Vivo by Dorsal Raphe Nucleus Electrical Stimulation.

Published in:

Journal of Neurochemistry, 1999, v. 73, n. 3, p. 1033, doi. 10.1046/j.1471-4159.1999.0731033.x

By:

De Deurwaerdère, Philippe;
Spampinato, Umberto

Publication type:

Article

Serotonin Stimulation of 5-HT4 Receptors Indirectly Enhances In Vivo Dopamine Release in the Rat Striatum.

Published in:

Journal of Neurochemistry, 1997, v. 68, n. 1, p. 195, doi. 10.1046/j.1471-4159.1997.68010195.x

By:

Deurwaerdère, Philippe De;
L'hirondel, Marie;
Bonhomme, Norbert;
Lucas, Guillaume;
Cheramy, André;
Spampinato, Umberto

Publication type:

Article

Serotonin Enhances Striatal Dopamine Outflow In Vivo Through Dopamine Uptake Sites.

Published in:

Journal of Neurochemistry, 1996, v. 66, n. 1, p. 210, doi. 10.1046/j.1471-4159.1996.66010210.x

By:

De Deurwaerdère, Philippe;
Bonhomme, Norbert;
Lucas, Guillaume;
Le Moal, Michel;
Spampinato, Umberto

Publication type:

Article

d-Fenfluramine Increases Striatal Extracellular Dopamine In Vivo Independently of Serotonergic Terminals or Dopamine Uptake Sites.

Published in:

Journal of Neurochemistry, 1995, v. 65, n. 3, p. 1100, doi. 10.1046/j.1471-4159.1995.65031100.x

By:

De Deurwaerdère, Philippe;
Bonhomme, Norbert;
Le Moal, Michel;
Spampinato, Umberto

Publication type:

Article

Editorial: Insights on neuroinflammatory response by microglia-targeted pharmacology.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1205859

By:

Raber, Jacob;
Caruncho, Hector J.;
De Deurwaerdere, Philippe;
Grilli, Massimo

Publication type:

Article

Monoaminergic control of spinal locomotor networks in SOD1G93A newborn mice.

Published in:

Frontiers in Neural Circuits, 2014, v. 8, p. 1, doi. 10.3389/fncir.2014.00077

By:

Milan, Léa;
Barrière, Grégory;
De Deurwaerdère, Philippe;
Cazalets, Jean-René;
Bertrand, Sandrine S.

Publication type:

Article