Works by De Cock, Pieter

Results: 37

A Pooled Population Pharmacokinetic Study of Oral and Intravenous Administration of Clavulanic Acid in Neonates and Infants: Targeting Effective Beta‐Lactamase Inhibition.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 1, p. 193, doi. 10.1002/cpt.3423

By:

Schouwenburg, Stef;
Keij, Fleur M.;
Tramper‐Stranders, Gerdien A.;
Kornelisse, René F.;
Reiss, Irwin K. M.;
De Cock, Pieter A. J. G.;
Dhont, Evelyn;
Watt, Kevin M.;
Muller, Anouk E.;
Flint, Robert B.;
Koch, Birgit C. P.;
Allegaert, Karel;
Preijers, Tim

Publication type:

Article

Concomitant Treatment with Voriconazole and Flucloxacillin: A Combination to Avoid.

Published in:

Antibiotics (2079-6382), 2021, v. 10, n. 9, p. 1112, doi. 10.3390/antibiotics10091112

By:

Van Daele, Ruth;
Wauters, Joost;
De Cock, Pieter;
Buyle, Franky;
Leys, John;
Van Brantegem, Pieter;
Gijsen, Matthias;
Annaert, Pieter;
Debaveye, Yves;
Lagrou, Katrien;
Peetermans, Willy E.;
Brüggemann, Roger J.;
Spriet, Isabel

Publication type:

Article

Reply to commenting letter for "Reliability of glomerular filtration rate estimating formulas compared to iohexol plasma clearance in critically ill children" by Smeets et al.

Published in:

2022

By:

Dhont, Evelyn;
Van Der Heggen, Tatjana;
De Cock, Pieter A.

Publication type:

Letter to the Editor

Reliability of glomerular filtration rate estimating formulas compared to iohexol plasma clearance in critically ill children.

Published in:

2022

By:

Dhont, Evelyn;
Windels, Charlotte;
Snauwaert, Evelien;
Van Der Heggen, Tatjana;
de Jaeger, Annick;
Dhondt, Laura;
Delanghe, Joris;
Croubels, Siska;
Walle, Johan Vande;
De Paepe, Peter;
De Cock, Pieter A.

Publication type:

journal article

Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology.

Published in:

2020

By:

Schrier, Lenneke;
Hadjipanayis, Adamos;
Stiris, Tom;
Ross-Russell, Rob I;
Valiulis, Arunas;
Turner, Mark A;
Zhao, Wei;
De Cock, Pieter;
de Wildt, Saskia N;
Allegaert, Karel;
van den Anker, John

Publication type:

journal article

Unraveling the Contribution of Fluid Therapy to the Development of Augmented Renal Clearance in a Piglet Model.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.607101

By:

Dhondt, Laura;
Croubels, Siska;
De Paepe, Peter;
Goethals, Klara;
De Cock, Pieter;
Devreese, Mathias

Publication type:

Article

Conventional Pig as Animal Model for Human Renal Drug Excretion Processes: Unravelling the Porcine Renal Function by Use of a Cocktail of Exogenous Markers.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00883

By:

Dhondt, Laura;
Croubels, Siska;
De Paepe, Peter;
Wallis, Steven C.;
Pandey, Saurabh;
Roberts, Jason A.;
Lipman, Jeffrey;
De Cock, Pieter;
Devreese, Mathias

Publication type:

Article

General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 4985, doi. 10.1111/bcp.15571

By:

Bouazza, Naïm;
Dokoumetzidis, Aristides;
Knibbe, Catherijne A. J.;
de Wildt, Saskia N.;
Ambery, Claire;
De Cock, Pieter A.;
Gasthuys, Elke;
Foissac, Frantz;
Urien, Saïk;
Hamberg, Anna‐Karin;
Poggesi, Italo;
Zhao, Wei;
Vermeulen, An;
Standing, Joseph F.;
Tréluyer, Jean‐Marc

Publication type:

Article

Current knowledge, challenges and innovations in developmental pharmacology: A combined conect4children Expert Group and European Society for Developmental, Perinatal and Paediatric Pharmacology White Paper.

Published in:

British Journal of Clinical Pharmacology, 2022, v. 88, n. 12, p. 4965, doi. 10.1111/bcp.14958

By:

Smits, Anne;
Annaert, Pieter;
Cavallaro, Giacomo;
De Cock, Pieter A. J. G.;
de Wildt, Saskia N.;
Kindblom, Jenny M.;
Lagler, Florian B.;
Moreno, Carmen;
Pokorna, Paula;
Schreuder, Michiel F.;
Standing, Joseph F.;
Turner, Mark A.;
Vitiello, Benedetto;
Zhao, Wei;
Weingberg, Annelie‐Martina;
Willmann, Raffaella;
van den Anker, John;
Allegaert, Karel

Publication type:

Article

Variation in vancomycin dosing and therapeutic drug monitoring practices in neonatal intensive care units.

Published in:

International Journal of Clinical Pharmacy, 2022, v. 44, n. 2, p. 564, doi. 10.1007/s11096-021-01345-9

By:

van der Veen, Anouk;
Somers, Annemie;
Vanhaesebrouck, Sophie;
ter Heine, Rob;
Brüggemann, Roger;
Allegaert, Karel;
De Cock, Pieter

Publication type:

Article

Vancomycin dosing and therapeutic drug monitoring practices: guidelines versus real-life.

Published in:

International Journal of Clinical Pharmacy, 2021, v. 43, n. 5, p. 1394, doi. 10.1007/s11096-021-01266-7

By:

Van Der Heggen, Tatjana;
Buyle, Franky M.;
Claus, Barbara;
Somers, Annemie;
Schelstraete, Petra;
De Paepe, Peter;
Vanhaesebrouck, Sophie;
De Cock, Pieter A. J. G.

Publication type:

Article

Estimation of Ontogeny Functions for Renal Transporters Using a Combined Population Pharmacokinetic and Physiology-Based Pharmacokinetic Approach: Application to OAT1,3.

Published in:

AAPS Journal, 2021, v. 23, n. 3, p. 1, doi. 10.1208/s12248-021-00595-9

By:

Cristea, Sînziana;
Krekels, Elke H. J.;
Allegaert, Karel;
De Paepe, Peter;
de Jaeger, Annick;
De Cock, Pieter;
Knibbe, Catherijne A. J.

Publication type:

Article

Reproducibility of fluid status measured by bioelectrical impedance analysis in healthy volunteers: a key requirement to monitor fluid status in the intensive care unit.

Published in:

Anaesthesiology Intensive Therapy / Anestezjologia, Intensywna Terapia, 2021, v. 53, n. 3, p. 193, doi. 10.5114/ait.2021.105826

By:

Gijsen, Matthias;
Simons, Eline;
De Cock, Pieter;
Malbrain, Manu L. N. G.;
Wauters, Joost;
Spriet, Isabel

Publication type:

Article

Dose rationale and pharmacokinetics of dexmedetomidine in mechanically ventilated new-borns: impact of design optimisation.

Published in:

European Journal of Clinical Pharmacology, 2019, v. 75, n. 10, p. 1393, doi. 10.1007/s00228-019-02708-y

By:

van Dijkman, Sven C.;
De Cock, Pieter A. J. G.;
Smets, Koenraad;
Decaluwe, Wim;
Smits, Anne;
Allegaert, Karel;
Vande Walle, Johan;
De Paepe, Peter;
Della Pasqua, Oscar

Publication type:

Article

Pharmacokinetics and Target Attainment of Teicoplanin: A Systematic Review.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 4, p. 467, doi. 10.1007/s40262-025-01483-7

By:

Mouton, Jaap W. A.;
De Clercq, Arnaud;
De Paepe, Peter;
Petrovic, Mirko;
Desmet, Tania;
Brüggemann, Roger J.;
Schouten, Jeroen A.;
Jager, Nynke G. L.;
De Cock, Pieter A.

Publication type:

Article

A Pooled Pharmacokinetic Analysis for Piperacillin/Tazobactam Across Different Patient Populations: From Premature Infants to the Elderly: A Pooled PK Analysis for Piperacillin/Tazobactam Across Different Patient Populations: D. Kong et al.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 1, p. 107, doi. 10.1007/s40262-024-01460-6

By:

Kong, Daming;
Roberts, Jason A.;
Lipman, Jeffrey;
Taccone, Fabio Silvio;
Cohen-Wolkowiez, Michael;
Sime, Fekade B.;
Tsai, Danny;
De Cock, Pieter A. J. G.;
Jaruratanasirikul, Sutep;
Dhaese, Sofie A. M.;
Udy, Andrew A.;
Felton, Timothy W.;
Michelet, Robin;
Thibault, Céline;
Koomen, Jeroen V.;
Eleveld, Douglas J.;
Struys, Michel M. R. F.;
De Waele, Jan J.;
Colin, Pieter J.;
Damen, Caroline

Publication type:

Article

Penetration of Antibiotics into Subcutaneous and Intramuscular Interstitial Fluid: A Meta-Analysis of Microdialysis Studies in Adults.

Published in:

Clinical Pharmacokinetics, 2024, v. 63, n. 7, p. 965, doi. 10.1007/s40262-024-01394-z

By:

De Sutter, Pieter-Jan;
Hermans, Eline;
De Cock, Pieter;
Van Bocxlaer, Jan;
Gasthuys, Elke;
Vermeulen, An

Publication type:

Article

Have We Neglected to Study Target-Site Drug Exposure in Children? A Systematic Review of the Literature.

Published in:

Clinical Pharmacokinetics, 2024, v. 63, n. 4, p. 439, doi. 10.1007/s40262-024-01364-5

By:

Hermans, Eline;
Meersschaut, Jozefien;
Van herteryck, Isis;
Devreese, Mathias;
Walle, Johan Vande;
De Paepe, Peter;
De Cock, Pieter A.

Publication type:

Article

Pharmacokinetics and Target Attainment of ß-lactam Antibiotics in Older People: A Systematic Review of Current Literature.

Published in:

Clinical Pharmacokinetics, 2023, v. 62, n. 1, p. 1, doi. 10.1007/s40262-022-01196-1

By:

Vervalcke, Jeroen;
De Clercq, Arnaud;
De Paepe, Peter;
Petrovic, Mirko;
Desmet, Tania;
De Cock, Pieter A.

Publication type:

Article

Pharmacokinetics/Pharmacodynamics of Antiviral Agents Used to Treat SARS-CoV-2 and Their Potential Interaction with Drugs and Other Supportive Measures: A Comprehensive Review by the PK/PD of Anti-Infectives Study Group of the European Society of Antimicrobial Agents

Published in:

Clinical Pharmacokinetics, 2020, v. 59, n. 10, p. 1195, doi. 10.1007/s40262-020-00924-9

By:

Zeitlinger, Markus;
Koch, Birgit C. P.;
Bruggemann, Roger;
De Cock, Pieter;
Felton, Timothy;
Hites, Maya;
Le, Jennifer;
Luque, Sonia;
MacGowan, Alasdair P.;
Marriott, Deborah J. E.;
Muller, Anouk E.;
Nadrah, Kristina;
Paterson, David L.;
Standing, Joseph F.;
Telles, João P.;
Wölfl-Duchek, Michael;
Thy, Michael;
Roberts, Jason A.

Publication type:

Article

The use of information technology to improve interdisciplinary communication during infectious diseases ward rounds on the paediatric intensive care unit.

Published in:

Scientific Reports, 2024, v. 13, n. 1, p. 1, doi. 10.1038/s41598-024-51986-9

By:

Willems, Jef;
Heyndrickx, Adeline;
Schelstraete, Petra;
Gadeyne, Bram;
De Cock, Pieter;
Vandendriessche, Stien;
Depuydt, Pieter

Publication type:

Article

Predictors of augmented renal clearance based on iohexol plasma clearance in critically ill children.

Published in:

Pediatric Nephrology, 2024, v. 39, n. 5, p. 1607, doi. 10.1007/s00467-023-06221-4

By:

Dhont, Evelyn;
Van Der Heggen, Tatjana;
Snauwaert, Evelien;
Willems, Jef;
Croubels, Siska;
Delanghe, Joris;
De Waele, Jan J.;
Colman, Roos;
Vande Walle, Johan;
De Paepe, Peter;
De Cock, Pieter A.

Publication type:

Article

Augmented renal clearance in pediatric intensive care: are we undertreating our sickest patients?

Published in:

Pediatric Nephrology, 2020, v. 35, n. 1, p. 25, doi. 10.1007/s00467-018-4120-2

By:

Dhont, Evelyn;
Van Der Heggen, Tatjana;
De Jaeger, Annick;
Vande Walle, Johan;
De Paepe, Peter;
De Cock, Pieter A.

Publication type:

Article

Augmented renal clearance: a common condition in critically ill children.

Published in:

Pediatric Nephrology, 2019, v. 34, n. 6, p. 1099, doi. 10.1007/s00467-019-04205-x

By:

Van Der Heggen, Tatjana;
Dhont, Evelyn;
Peperstraete, Harlinde;
Delanghe, Joris R.;
Vande Walle, Johan;
De Paepe, Peter;
De Cock, Pieter A.

Publication type:

Article

Optimizing the Use of Antibiotic Agents in the Pediatric Intensive Care Unit: A Narrative Review.

Published in:

Pediatric Drugs, 2021, v. 23, n. 1, p. 39, doi. 10.1007/s40272-020-00426-y

By:

Willems, Jef;
Hermans, Eline;
Schelstraete, Petra;
Depuydt, Pieter;
De Cock, Pieter

Publication type:

Article

Dose optimization of β-lactam antibiotics in children: from population pharmacokinetics to individualized therapy.

Published in:

Expert Opinion on Drug Metabolism & Toxicology, 2024, v. 20, n. 8, p. 787, doi. 10.1080/17425255.2024.2385403

By:

Ngougni Pokem, Perrin;
Vanneste, Dorian;
Schouwenburg, Stef;
Abdulla, Alan;
Gijsen, Matthias;
Dhont, Evelyn;
Van der Linden, Dimitri;
Spriet, Isabel;
De Cock, Pieter;
Koch, Birgit;
Van Bambeke, Françoise;
Wijnant, Gert-Jan

Publication type:

Article

Physiologically based pharmacokinetic (PBPK) modeling and simulation in neonatal drug development: how clinicians can contribute.

Published in:

Expert Opinion on Drug Metabolism & Toxicology, 2019, v. 15, n. 1, p. 25, doi. 10.1080/17425255.2019.1558205

By:

Smits, Anne;
De Cock, Pieter;
Vermeulen, An;
Allegaert, Karel

Publication type:

Article

A multicentric, randomized, controlled clinical trial to study the impact of bedside model-informed precision dosing of vancomycin in critically ill children—BENEFICIAL trial.

Published in:

Trials, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13063-024-08512-z

By:

De Cock, Pieter A.;
Colman, Roos;
Amza, Anca;
De Paepe, Peter;
De Pla, Hans;
Vanlanduyt, Lieselot;
Van der Linden, Dimitri;
Schelstraete, Petra;
Cools, Filip;
Clarysse, Alexander;
Debouver, Phebe;
Biarent, Dominique;
Vens, Daphne Vania;
Smits, Anne;
Godart, Valerie;
Vanhaesebrouck, Sophie;
Dhont, Evelyn;
Bordon, Victoria;
Mauel, Reiner;
Van Der Werff Ten Bosch, Jutte

Publication type:

Article

Assessment of self-perceived knowledge of key clinical pharmacology concepts and educational needs among European Paediatric Intensive Care Units: an ESPNIC survey.

Published in:

Intensive Care Medicine - Paediatric & Neonatal, 2024, v. 2, n. 1, p. 1, doi. 10.1007/s44253-024-00044-3

By:

Daverio, Marco;
Sperotto, Francesca;
Poletto, Elisa;
Bianzina, Stefania;
Butragueño Laiseca, Laura;
Cardona, Francesco;
De Cock, Pieter;
De Hoog, Matthijs;
George, Sylvia;
Oualha, Mehdi;
Pokorna, Paula;
Sfriso, Francesca;
Tessari, Anna;
de Wildt, Saskia N;
Amigoni, Angela

Publication type:

Article

Pharmacokinetics of two formulations of omeprazole administered through a gastrostomy tube in patients with severe neurodevelopmental problems.

Published in:

British Journal of Clinical Pharmacology, 2011, v. 72, n. 6, p. 990, doi. 10.1111/j.1365-2125.2011.04038.x

By:

Boussery, Koen;
De Smet, Julie;
De Cock, Pieter;
Vande Velde, Saskia;
Mehuys, Els;
De Paepe, Peter;
Remon, Jean Paul;
Van Bocxlaer, Jan F. P.;
Van Winckel, Myriam

Publication type:

Article

Retrospective analysis of a flucloxacillin oral absorption test in patients requiring flucloxacillin therapy: results and determination of factors associated with adequate absorption.

Published in:

Acta Clinica Belgica, 2024, v. 79, n. 3, p. 184, doi. 10.1080/17843286.2024.2382981

By:

Sanne, De Smet;
de Cock, Pieter;
Nick, Verougstraete;
Franky, Buyle;
Boelens, Jerina;
Huis in 't Veld, Diana

Publication type:

Article

Impact of model-informed precision dosing in adults receiving vancomycin via continuous infusion: a randomized, controlled clinical trial.

Published in:

Trials, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13063-024-07965-6

By:

Van Wynsberge, Glenn;
Grootaert, Veerle;
Buyle, Franky;
Van Praet, Jens;
Colman, Roos;
Moors, Ine;
Somers, Annemie;
Veld, Diana Huis in 't;
De Cock, Pieter;
Bigler, Kim;
Capiau, Andreas;
Claus, Barbara;
Degroote, Laure;
De Keulenaer, Julie;
Deryckere, Sabine;
Deschepper, Lotte;
De Smet, Sanne;
De Smet, Veronique;
Heus, Astrid;
Huys, Liesbeth

Publication type:

Article

Volumetric absorptive microsampling as an alternative sampling strategy for the determination of paracetamol in blood and cerebrospinal fluid.

Published in:

Analytical & Bioanalytical Chemistry, 2019, v. 411, n. 1, p. 181, doi. 10.1007/s00216-018-1427-6

By:

Delahaye, Lisa;
Dhont, Evelyn;
De Cock, Pieter;
De Paepe, Peter;
Stove, Christophe P.

Publication type:

Article

Therapeutic drug monitoring versus Bayesian AUC-based dosing for vancomycin in routine practice: a cost–benefit analysis.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2025, v. 80, n. 3, p. 857, doi. 10.1093/jac/dkaf011

By:

Claus, Barbara O M;
Smedt, Delphine De;
Cock, Pieter A De

Publication type:

Article

Dose optimization of piperacillin/tazobactam in critically ill children.

Published in:

2017

By:

De Cock, Pieter A. J. G.;
van Dijkman, Sven C.;
de Jaeger, Annick;
Willems, Jef;
Carlier, Mieke;
Verstraete, Alain G.;
Delanghe, Joris R.;
Robays, Hugo;
Walle, Johan Vande;
Pasqua, Oscar E. Della;
De Paepe, Peter;
Vande Walle, Johan;
Della Pasqua, Oscar E

Publication type:

journal article

Impact of vancomycin protein binding on target attainment in critically ill children: back to the drawing board?

Published in:

2017

By:

De Cock, Pieter A. J. G.;
Desmet, Sarah;
De Jaeger, Annick;
Biarent, Dominique;
Dhont, Evelyn;
Herck, Ingrid;
Vens, Daphné;
Colman, Sofie;
Stove, Veronique;
Commeyne, Sabrina;
Walle, Johan Vande;
De Paepe, Peter;
Vande Walle, Johan

Publication type:

journal article

Population pharmacokinetics of cefazolin before, during and after cardiopulmonary bypass to optimize dosing regimens for children undergoing cardiac surgery.

Published in:

2017

By:

De Cock, Pieter A. J. G.;
Mulla, Hussain;
Desmet, Sarah;
De Somer, Filip;
McWhinney, Brett C.;
Ungerer, Jacobus P. J.;
Moerman, Annelies;
Commeyne, Sabrina;
Walle, Johan Vande;
Francois, Katrien;
Van Hasselt, Johan G. C.;
De Paepe, Peter;
Vande Walle, Johan

Publication type:

journal article