Works by De Clercq, Erik
Results: 295
Sixty Years at the Rega Institute.
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- Viruses (1999-4915), 2025, v. 17, n. 2, p. 222, doi. 10.3390/v17020222
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- Article
Serum and urine concentrations of oral bromovinyldeoxyuridine in humans as monitored by a bioassay system based on varicella-zoster virus focus inhibition.
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- Journal of Medical Virology, 1987, v. 22, n. 1, p. 17, doi. 10.1002/jmv.1890220104
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- Article
New synthesis and anti-HIV and antiviral properties of 3-arylsulfonyl derivatives of 4-ydroxycoumarin and 4-hydroxyquinolone.
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- Pharmaceutical Chemistry Journal, 2008, v. 42, n. 5, p. 265, doi. 10.1007/s11094-008-0103-0
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- Article
Discovery of piperidine-substituted thiazolo[5,4-d]pyrimidine derivatives as potent and orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitors.
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- Communications Chemistry, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42004-019-0174-8
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Synthesis, and prediction of molecular properties and antimicrobial activity of some acylhydrazones derived from N-(arylsulfonyl)methionine.
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- Turkish Journal of Chemistry, 2016, v. 40, n. 3, p. 510, doi. 10.3906/kim-1509-21
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- Article
Niacin esters of chalcones with tumor-selective properties.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1451, doi. 10.3109/14756366.2016.1144595
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Design, synthesis, antimicrobial activity and anti-HIV activity evaluation of novel hybrid quinazoline-triazine derivatives.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2014, v. 29, n. 1, p. 100, doi. 10.3109/14756366.2012.755622
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Synthesis, antineoplastic and cytotoxic activities of some mononuclear Ru(II) complexes.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 4, p. 513, doi. 10.3109/14756360903357577
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Synthesis, antimicrobial and antiviral activity of substituted benzimidazoles.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 5, p. 1161, doi. 10.1080/14756360802694427
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- Article
Synthesis and evaluation of in vitro antiviral activity of 2-[3-(substituted phenyl)-4,5-dihydro-1 H-5-pyrazolyl]benzofuran-3-yl chloride derivatives.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 4, p. 949, doi. 10.1080/14756360802560677
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Synthesis and evaluation of in vitro antiviral activity of novel phenoxy acetic acid derivatives.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 3, p. 876, doi. 10.1080/14756360802447917
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- Article
1-Arylmethyl-2,3-dioxo-2,3-dihydroindole thiosemicarbazones as leads for developing cytotoxins and anticonvulsants.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 2, p. 537, doi. 10.1080/14756360802234885
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- Article
Molecular modifications of 2-arylidene-1-indanones leading to increased cytotoxic potencies.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 1, p. 37, doi. 10.1080/14756360600958057
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- Article
AMD3100/CXCR4 inhibitor.
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- 2015
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- Opinion
Bromovinyldeoxyuridine treatment of herpetic keratitis clinically resistant to other antiviral agents.
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- Current Eye Research, 1991, v. 10, n. s1, p. 193, doi. 10.3109/02713689109020379
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- Article
Intentional reactivation of latent ocular herpes infection during BVDU therapy.
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- Current Eye Research, 1987, v. 6, n. 12, p. 1471, doi. 10.3109/02713688709044511
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Experimental thymidine kinase-deficient HSV-1 keratitis: Therapeutic attempts.
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- Current Eye Research, 1987, v. 6, n. 4, p. 579, doi. 10.3109/02713688709025216
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- Article
Desferrioxamine enhances aids-associated Kaposi's sarcoma tumor development in a xenograft model.
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- International Journal of Cancer, 2002, v. 100, n. 2, p. 140, doi. 10.1002/ijc.10475
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- Article
Potent inhibition of hemangiosarcoma development in mice by cidofovir.
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- International Journal of Cancer, 2001, v. 92, n. 2, p. 161, doi. 10.1002/1097-0215(200102)9999:9999<::AID-IJC1183>3.0.CO;2-K
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- Article
The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs
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- FEBS Letters, 2005, v. 579, n. 11, p. 2294, doi. 10.1016/j.febslet.2005.02.077
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Human herpesvirus 6 infection arrests cord blood mononuclear cells in G<sub>2</sub> phase of the cell cycle
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- FEBS Letters, 2004, v. 560, n. 1-3, p. 25, doi. 10.1016/S0014-5793(04)00035-3
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- Article
Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry
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- FEBS Letters, 2003, v. 546, n. 2/3, p. 300, doi. 10.1016/S0014-5793(03)00609-4
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- Article
Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4
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- FEBS Letters, 2002, v. 527, n. 1-3, p. 255, doi. 10.1016/S0014-5793(02)03143-5
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- Article
Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase.
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- FEBS Letters, 2002, v. 510, n. 1-2, p. 83, doi. 10.1016/S0014-5793(01)03233-1
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Synthesis and biological evaluation of acyclic nucleotide analogues with a furo[2,3-d]pyrimidin-2(3H)-one base.
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- Canadian Journal of Chemistry, 2010, v. 88, n. 7, p. 628, doi. 10.1139/V10-054
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Synthesis and biological evaluation of 5-(alkyn-1-yl)-1-(p-toluenesulfonyl)uracil derivatives.
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- Canadian Journal of Chemistry, 2006, v. 84, n. 4, p. 580, doi. 10.1139/v06-041
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- Article
Antiproliferative and Antiviral Activity of Three Libraries of Adamantane Derivatives.
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- Archiv der Pharmazie, 2014, v. 347, n. 5, p. 334, doi. 10.1002/ardp.201300345
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- Article
Some Hydrazones of 2-Aroylamino-3-methylbutanohydrazide: Synthesis, Molecular Modeling Studies, and Identification as Stereoselective Inhibitors of HIV-1.
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- Archiv der Pharmazie, 2013, v. 346, n. 2, p. 140, doi. 10.1002/ardp.201200311
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Synthesis and Evaluation of Novel 4-Substituted Styryl Quinazolines as Potential Antimicrobial Agents.
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- Archiv der Pharmazie, 2012, v. 345, n. 12, p. 964, doi. 10.1002/ardp.201200291
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- Article
Non-nucleoside HIV Reverse Transcriptase Inhibitors, Part 6[1]: Synthesis and Anti-HIV Activity of Novel 2-[(Arylcarbonylmethyl)thio]-6-arylthio DABO Analogues.
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- Archiv der Pharmazie, 2005, v. 338, n. 10, p. 457, doi. 10.1002/ardp.200400961
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Synthesis of 3-Nitrosoimidazo[1,2- a]pyridine Derivatives as Potential Antiretroviral Agents.
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- Archiv der Pharmazie, 2001, v. 334, n. 7, p. 224, doi. 10.1002/1521-4184(200107)334:7<224::AID-ARDP224>3.0.CO;2-7
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Synthesis and Antiviral and Cytostatic Activities of Carbocyclic Nucleosides Incorporating a Modified Cyclobutane Ring.
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- Archiv der Pharmazie, 1999, v. 332, n. 10, p. 348, doi. 10.1002/(SICI)1521-4184(199910)332:10<348::AID-ARDP348>3.0.CO;2-H
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Inhibition of Human Immunodeficiency Virus Type (HIV-1) Replication by some Diversely Functionalized Spirocyclopropyl Derivatives.
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- Archiv der Pharmazie, 1999, v. 332, n. 5, p. 163, doi. 10.1002/(SICI)1521-4184(19995)332:5<163::AID-ARDP163>3.0.CO;2-2
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Novel Carbocyclic Nucleosides Containing a Cyclopentyl Ring. Adenosine and Uridine Analogues.
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- Archiv der Pharmazie, 1997, v. 330, n. 8, p. 265, doi. 10.1002/ardp.19973300807
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Synthesis of 5′- N-(α-Amino-β-mercaptoacyl)amino-5′-deoxynucleosides as potential antiviral compounds.
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- Archiv der Pharmazie, 1991, v. 324, n. 8, p. 497, doi. 10.1002/ardp.2503240807
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- Article
Antiviral treatment is more effective than smallpox vaccination upon lethal monkeypox virus infection.
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- Nature, 2006, v. 439, n. 7077, p. 745, doi. 10.1038/nature04295
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- Article
SYNTHESIS AND IN VITRO CYTOTOXIC AND ANTIVIRAL ACTIVITIES OF 1-(2,5,6-TRIDEOXY-6-HALOGENOHEPT-5-ENOFURANURONONITRILE)THYMINE AND DERIVATIVES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2002, v. 21, n. 3, p. 191, doi. 10.1081/NCN-120003285
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- Article
SYNTHESIS, ANTIVIRAL AND CYTOSTATIC ACTIVITIES, OF CARBOCYCLIC NUCLEOSIDES INCORPORATING A MODIFIED CYCLOPENTANE RING. IV. ADENOSINE AND URIDINE ANALOGUES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2002, v. 21, n. 3, p. 243, doi. 10.1081/NCN-120003289
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- Article
SYNTHESIS AND BIOLOGICAL EVALUATION OF ISONUCLEOSIDES DERIVED FROM METHYL 3,5-ANHYDRO-2-O-(2-FLUOROBENZYL)-d-XYLOFURANOSIDES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2002, v. 21, n. 3, p. 257, doi. 10.1081/NCN-120003290
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SYNTHESIS AND ANTI-HIV ACTIVITY OF THYMIDINE ANALOGUES BEARING A 4′-CYANOVINYL GROUP AND SOME DERIVATIVES THEREOF.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 12, p. 1927, doi. 10.1081/NCN-100108323
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THIOSUGARS. VIII.* PREPARATION OF NEW 4′-THIO-L-LYXO PYRIMIDINE NUCLEOSIDE ANALOGUES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 9, p. 1625, doi. 10.1081/NCN-100105900
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NOVEL ARYL SUBSTITUTED BICYCLIC FURO NUCLEOSIDES AS EXTREMELY POTENT AND SELECTIVE ANTI-VZV AGENTS.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 287, doi. 10.1081/NCN-100002299
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SYNTHESIS AND IN VITRO EVALUATION OF NOVEL ANTI-VARICELLA-ZOSTER VIRUS (VZV) NUCLEOSIDES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 653, doi. 10.1081/NCN-100002343
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BICYCLIC NUCLEOSIDE INHIBITORS OF VARICELLA-ZOSTER VIRUS (VZV): EFFECT OF TERMINAL UNSATURATION IN THE SIDE-CHAIN.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 763, doi. 10.1081/NCN-100002425
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SYNTHESIS AND IN VITRO ANTIVIRAL ACTIVITY EVALUATION OF 9-(2-AZIDO-2,3-DIDEOXY-β-D-THREO-PENTOFURANOSYL)ADENINE DERIVATIVES.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 1053, doi. 10.1081/NCN-100002490
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BICYCLIC FURO PYRIMIDINE NUCLEOSIDES WITH ARYLOXYPHENYL AND HALOPHENYL SUBSTITUTED SIDE CHAINS AS POTENT AND SELECTIVE VARICELLA-ZOSTER VIRUS INHIBITORS.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 4-7, p. 1063, doi. 10.1081/NCN-100002492
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SYNTHESIS OF 1-(2-DEOXY-β-D- RIBOFURANOSYL)-2,4-DIFLUORO-5-SUBSTITUTED-BENZENE THYMIDINE MIMICS,* SOME RELATED α-ANOMERS, AND THEIR EVALUATION AS ANTIVIRAL AND ANTICANCER AGENTS.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 1/2, p. 11, doi. 10.1081/NCN-100001435
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SYNTHESIS OF 1-(2-DEOXY-β-D-RIBOFURANOSYL)-2,4-DIFLUORO-5-SUBSTITUTED-BENZENES*: “THYMINE REPLACEMENT” ANALOGS OF THYMIDINE FOR EVALUATION AS ANTICANCER AND ANTIVIRAL AGENTS.
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- Nucleosides, Nucleotides & Nucleic Acids, 2001, v. 20, n. 1/2, p. 41, doi. 10.1081/NCN-100001436
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Syntheses of 1-[(2-Hydroxyethoxy)methyl]- and 1-[(1,3-Dihydroxy-2-Propoxy)methyl]- Derivatives of 5-Substituted-2,4-difluorobenzene: Unnatural Acyclo Thymidine Mimics for Evaluation as Anticancer and Antiviral Agents.
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- Nucleosides, Nucleotides & Nucleic Acids, 2000, v. 19, n. 9, p. 1397, doi. 10.1080/15257770008033850
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Highly Stereoselective Synthesis and Biological Properties of Nucleoside Analogues Bearing a Spiro Inserted Oxirane Ring.
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- Nucleosides, Nucleotides & Nucleic Acids, 2000, v. 19, n. 4, p. 775, doi. 10.1080/15257770008035024
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