OpenURL Connection Search

Select item for more details and to access through your institution.

Challenges and Opportunities for Companies to Build HTA/Payer Perspectives Into Drug Development Through the Use of a Dynamic Target Product Profile.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.948161
By:
- Ting Wang;
- McAuslane, Neil;
- Goettsch, Wim G.;
- Leufkens, Hubert G. M.;
- De Bruin, Marie L.
Publication type:
Article
Randomized controlled trials of COX-2 inhibitors: an analysis of doses used and trends over time to investigate implications for comparative safety.
Published in:
2011
By:
- Stefansdottir G;
- De Bruin ML;
- Knol MJ;
- Grobbee DE;
- Leufkens HG;
- Stefansdottir, Gudrun;
- De Bruin, Marie L;
- Knol, Mirjam J;
- Grobbee, Diederick E;
- Leufkens, Hubert G M
Publication type:
journal article
The association of diabetes mellitus and insulin treatment with expression of insulin-related proteins in breast tumors.
Published in:
2018
By:
- Bronsveld, Heleen K;
- De Bruin, Marie L;
- Wesseling, Jelle;
- Sanders, Joyce;
- Hofland, Ingrid;
- Jensen, Vibeke;
- Bazelier, Marloes T;
- Ter Braak, Bas;
- de Boer, Anthonius;
- Vestergaard, Peter;
- Schmidt, Marjanka K
Publication type:
journal article
Use of incretin agents and risk of acute and chronic pancreatitis: A population-based cohort study.
Published in:
Diabetes, Obesity & Metabolism, 2017, v. 19, n. 3, p. 401, doi. 10.1111/dom.12833
By:
- Knapen, Lotte M.;
- de Jong, Roy G. P. J.;
- Driessen, Johanna H. M.;
- Keulemans, Yolande C.;
- van Erp, Nielka P.;
- De Bruin, Marie L.;
- Leufkens, Hubert G. M.;
- Croes, Sander;
- de Vries, Frank
Publication type:
Article
Resting Heart Rate Is a Risk Factor for Mortality in Chronic Obstructive Pulmonary Disease, but Not for Exacerbations or Pneumonia.
Published in:
PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105152
By:
- Warnier, Miriam J.;
- Rutten, Frans H.;
- de Boer, Anthonius;
- Hoes, Arno W.;
- De Bruin, Marie L.
Publication type:
Article
Regulatory, health technology assessment and company interactions: the current landscape and future ecosystem for drug development, review and reimbursement.
Published in:
International Journal of Technology Assessment in Health Care, 2023, v. 39, n. 1, p. 1, doi. 10.1017/S0266462323000144
By:
- Ting Wang;
- McAuslane, Neil;
- Goettsch, Wim G.;
- Leufkens, Hubert G. M.;
- De Bruin, Marie L.
Publication type:
Article
Comparing risk of major bleeding between users of different oral anticoagulants in patients with nonvalvular atrial fibrillation.
Published in:
British Journal of Clinical Pharmacology, 2021, v. 87, n. 3, p. 988, doi. 10.1111/bcp.14450
By:
- Souverein, Patrick C.;
- Ham, Hendrika A.;
- Huerta, Consuelo;
- Merino, Elisa Martín;
- Montero, Dolores;
- León‐Muñoz, Luz M.;
- Schmiedl, Sven;
- Heeke, Andreas;
- Rottenkolber, Marietta;
- Andersen, Morten;
- Aakjaer, Mia;
- De Bruin, Marie L.;
- Klungel, Olaf H.;
- Gardarsdottir, Helga
Publication type:
Article
Characteristics and follow-up of postmarketing studies of conditionally authorized medicines in the EU.
Published in:
British Journal of Clinical Pharmacology, 2016, v. 82, n. 1, p. 213, doi. 10.1111/bcp.12940
By:
- Hoekman, Jarno;
- Klamer, Thea T.;
- Mantel‐Teeuwisse, Aukje K.;
- Leufkens, Hubert G. M.;
- De Bruin, Marie L.
Publication type:
Article
Influence of metformin intake on the risk of bladder cancer in type 2 diabetes patients.
Published in:
British Journal of Clinical Pharmacology, 2015, v. 80, n. 6, p. 1464, doi. 10.1111/bcp.12740
By:
- Goossens, Maria E.;
- Buntinx, Frank;
- Zeegers, Maurice P.;
- Driessen, J.H.M.;
- De Bruin, Marie L.;
- De Vries, Frank
Publication type:
Article
Major bleeding in users of direct oral anticoagulants in atrial fibrillation: A pooled analysis of results from multiple population‐based cohort studies.
Published in:
Pharmacoepidemiology & Drug Safety, 2021, v. 30, n. 10, p. 1339, doi. 10.1002/pds.5317
By:
- van den Ham, Hendrika A.;
- Souverein, Patrick C.;
- Klungel, Olaf H.;
- Platt, Robert W.;
- Ernst, Pierre;
- Dell'Aniello, Sophie;
- Schmiedl, Sven;
- Grave, Birgit;
- Rottenkolber, Marietta;
- Huerta, Consuelo;
- Martín Merino, Elisa;
- León‐Muñoz, Luz M.;
- Montero, Dolores;
- Andersen, Morten;
- Aakjær, Mia;
- De Bruin, Marie L.;
- Gardarsdottir, Helga
Publication type:
Article
Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence.
Published in:
Breast Cancer Research, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13058-015-0611-2
By:
- Bronsveld, Heleen K.;
- Braak, Bas ter;
- Karlstad, Øystein;
- Vestergaard, Peter;
- Starup-Linde, Jakob;
- Bazelier, Marloes T.;
- De Bruin, Marie L.;
- de Boer, Anthonius;
- Siezen, Christine L. E.;
- van de Water, Bob;
- van der Laan, Jan Willem;
- Schmidt, Marjanka K.
Publication type:
Article
Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence.
Published in:
2015
By:
- Bronsveld, Heleen K;
- Ter Braak, Bas;
- Karlstad, øystein;
- Vestergaard, Peter;
- Starup-Linde, Jakob;
- Bazelier, Marloes T;
- De Bruin, Marie L;
- de Boer, Anthonius;
- Siezen, Christine L E;
- van de Water, Bob;
- van der Laan, Jan Willem;
- Schmidt, Marjanka K;
- Karlstad, Øystein
Publication type:
journal article
Predicting cardiac arrhythmias and sudden death in diabetic users of proarrhythmic drugs.
Published in:
2005
By:
- De Bruin, Marie L.;
- Van Staa, Tjeerd P.;
- Belitser, Svetlana V.;
- Leufkens, Hubert G. M.;
- Hoes, Arno W.
Publication type:
journal article
Infradiaphragmatic irradiation and high procarbazine doses increase colorectal cancer risk in Hodgkin lymphoma survivors.
Published in:
2017
By:
- van Eggermond, Anna M;
- Schaapveld, Michael;
- Janus, Cécile PM;
- de Boer, Jan Paul;
- Krol, Augustinus DG;
- Zijlstra, Josée M;
- van der Maazen, Richard WM;
- Kremer, Leontien C;
- van Leerdam, Monique E;
- Louwman, Marieke WJ;
- Visser, Otto;
- De Bruin, Marie L;
- Aleman, Berthe MP;
- van Leeuwen, Flora E;
- Janus, Cécile Pm;
- Zijlstra, Josée M
Publication type:
journal article
Postmarket Safety Communication for Protection of Public Health: A Comparison of Regulatory Policy in Australia, Canada, the European Union, and the United States.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1424, doi. 10.1002/cpt.2010
By:
- Bhasale, Alice L.;
- Sarpatwari, Ameet;
- De Bruin, Marie L.;
- Lexchin, Joel;
- Lopert, Ruth;
- Bahri, Priya;
- Mintzes, Barbara J.
Publication type:
Article
Pharmacogenetic‐Pharmacokinetic Interactions in Drug Marketing Authorization Applications via the European Medicines Agency Between 2014 and 2017.
Published in:
Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 2, p. 338, doi. 10.1002/cpt.1834
By:
- Maliepaard, Marc;
- Toiviainen, Timi;
- De Bruin, Marie L.;
- Meulendijks, Didier
Publication type:
Article
Postauthorization Changes to Specific Obligations of Conditionally Authorized Medicines in the European Union: A Retrospective Cohort Study.
Published in:
Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 2, p. 426, doi. 10.1002/cpt.1169
By:
- Bloem, Lourens T.;
- Mantel‐Teeuwisse, Aukje K.;
- Leufkens, Hubert G. M.;
- De Bruin, Marie L.;
- Klungel, Olaf H.;
- Hoekman, Jarno
Publication type:
Article
When More Is Less: An Exploratory Study of the Precautionary Reporting Bias and Its Impact on Safety Signal Detection.
Published in:
Clinical Pharmacology & Therapeutics, 2018, v. 103, n. 2, p. 296, doi. 10.1002/cpt.879
By:
- Klein, Kevin;
- Scholl, Joep H. G.;
- De Bruin, Marie L.;
- van Puijenbroek, Eugène P.;
- Leufkens, Hubert G. M.;
- Stolk, Pieter
Publication type:
Article
Global Regulatory Differences for Gene- and Cell-Based Therapies: Consequences and Implications for Patient Access and Therapeutic Innovation.
Published in:
Clinical Pharmacology & Therapeutics, 2018, v. 103, n. 1, p. 120, doi. 10.1002/cpt.894
By:
- Coppens, Delphi G. M.;
- De Bruin, Marie L.;
- Leufkens, Hubert G. M.;
- Hoekman, Jarno
Publication type:
Article
In-hospital cardiac arrest is associated with use of non-antiarrhythmic QTc-prolonging drugs.
Published in:
British Journal of Clinical Pharmacology, 2007, v. 63, n. 2, p. 216, doi. 10.1111/j.1365-2125.2006.02722.x
By:
- De Bruin, Marie L.;
- Langendijk, Pim N. J.;
- Koopmans, Richard P.;
- Wilde, Arthur A. M.;
- Leufkens, Hubert G. M.;
- Hoes, Arno W.
Publication type:
Article
Diabetes and Breast Cancer Subtypes.
Published in:
PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170084
By:
- Bronsveld, Heleen K.;
- Jensen, Vibeke;
- Vahl, Pernille;
- De Bruin, Marie L.;
- Cornelissen, Sten;
- Sanders, Joyce;
- Auvinen, Anssi;
- Haukka, Jari;
- Andersen, Morten;
- Vestergaard, Peter;
- Schmidt, Marjanka K.
Publication type:
Article
Registries in European post-marketing surveillance: a retrospective analysis of centrally approved products, 2005-2013.
Published in:
Pharmacoepidemiology & Drug Safety, 2017, v. 26, n. 12, p. 1442, doi. 10.1002/pds.4196
By:
- Bouvy, Jacoline C.;
- Blake, Kevin;
- Slattery, Jim;
- De Bruin, Marie L.;
- Arlett, Peter;
- Kurz, Xavier
Publication type:
Article
Benefit-risk reassessment of medicines: a retrospective analysis of all safety-related referral procedures in Europe during 2001-2012.
Published in:
Pharmacoepidemiology & Drug Safety, 2016, v. 25, n. 9, p. 1004, doi. 10.1002/pds.4011
By:
- Bouvy, Jacoline C.;
- Huinink, Lotte;
- De Bruin, Marie L.
Publication type:
Article
The risk of acute liver injury associated with the use of antibiotics-evaluating robustness of results in the pharmacoepidemiological research on outcomes of therapeutics by a European consortium (PROTECT) project.
Published in:
Pharmacoepidemiology & Drug Safety, 2016, v. 25, p. 47, doi. 10.1002/pds.3841
By:
- Udo, Renate;
- Tcherny ‐ Lessenot, Stéphanie;
- Brauer, Ruth;
- Dolin, Paul;
- Irvine, David;
- Wang, Yunxun;
- Auclert, Laurent;
- Juhaeri, Juhaeri;
- Kurz, Xavier;
- Abenhaim, Lucien;
- Grimaldi, Lamiae;
- De Bruin, Marie L.
Publication type:
Article
Validity of diagnostic codes and laboratory measurements to identify patients with idiopathic acute liver injury in a hospital database.
Published in:
Pharmacoepidemiology & Drug Safety, 2016, v. 25, p. 21, doi. 10.1002/pds.3824
By:
- Udo, Renate;
- Maitland ‐ van der Zee, Anke H.;
- Egberts, Toine C. G.;
- den Breeijen, Johanna H.;
- Leufkens, Hubert G. M.;
- Solinge, Wouter W.;
- De Bruin, Marie L.
Publication type:
Article
Exposure to benzodiazepines (anxiolytics, hypnotics and related drugs) in seven European electronic healthcare databases: a cross-national descriptive study from the PROTECT-EU Project.
Published in:
Pharmacoepidemiology & Drug Safety, 2016, v. 25, p. 56, doi. 10.1002/pds.3825
By:
- Huerta, Consuelo;
- Abbing ‐ Karahagopian, Victoria;
- Requena, Gema;
- Oliva, Belén;
- Alvarez, Yolanda;
- Gardarsdottir, Helga;
- Miret, Montserrat;
- Schneider, Cornelia;
- Gil, Miguel;
- Souverein, Patrick C.;
- De Bruin, Marie L.;
- Slattery, Jim;
- De Groot, Mark C. H.;
- Hesse, Ulrik;
- Rottenkolber, Marietta;
- Schmiedl, Sven;
- Montero, Dolores;
- Bate, Andrew;
- Ruigomez, Ana;
- García ‐ Rodríguez, Luis Alberto
Publication type:
Article
The effect of exposure misclassification in spontaneous ADR reports on the time to detection of product-specific risks for biologicals: a simulation study.
Published in:
Pharmacoepidemiology & Drug Safety, 2016, v. 25, n. 3, p. 297, doi. 10.1002/pds.3929
By:
- Vermeer, Niels S.;
- Ebbers, Hans C.;
- Straus, Sabine M. J. M.;
- Leufkens, Hubert G. M.;
- Egberts, Toine C. G.;
- De Bruin, Marie L.
Publication type:
Article
Data management and data analysis techniques in pharmacoepidemiological studies using a pre-planned multi-database approach: a systematic literature review.
Published in:
Pharmacoepidemiology & Drug Safety, 2015, v. 24, n. 9, p. 897, doi. 10.1002/pds.3828
By:
- Bazelier, Marloes T.;
- Eriksson, Irene;
- Vries, Frank;
- Schmidt, Marjanka K.;
- Raitanen, Jani;
- Haukka, Jari;
- Starup ‐ Linde, Jakob;
- De Bruin, Marie L.;
- Andersen, Morten
Publication type:
Article
Pharmacogenetics of drug-induced arrhythmias: a feasibility study using spontaneous adverse drug reactions reporting data.
Published in:
Pharmacoepidemiology & Drug Safety, 2006, v. 15, n. 2, p. 99, doi. 10.1002/pds.1194
By:
- De Bruin, Marie L.;
- van Puijenbroek, Eugene P.;
- Bracke, Madelon;
- Hoes, Arno W.;
- Leufkens, Hubert G. M.
Publication type:
Article
Insulin glargine use and breast cancer risk: Associations with cumulative exposure.
Published in:
Acta Oncologica, 2016, v. 55, n. 7, p. 851, doi. 10.3109/0284186X.2016.1155736
By:
- Peeters, Paul J. H. L.;
- Bazelier, Marloes T.;
- Leufkens, Hubert G. M.;
- Auvinen, Anssi;
- van Staa, Tjeerd P.;
- de Vries, Frank;
- De Bruin, Marie L.
Publication type:
Article
Guidance for pediatric use in prescription information for novel medicinal products in the EU and the US.
Published in:
PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0266353
By:
- Christiansen, Helle;
- De Bruin, Marie L.;
- Frokjaer, Sven;
- Hallgreen, Christine E.
Publication type:
Article
Exercise echocardiography in asymptomatic survivors of childhood cancer treated with anthracyclines: A prospective follow-up study.
Published in:
Pediatric Blood & Cancer, 2010, v. 54, n. 4, p. 579, doi. 10.1002/pbc.22371
By:
- Sieswerda, Elske;
- Kremer, Leontien C.M.;
- Vidmar, Suzanna;
- De Bruin, Marie L.;
- Smibert, Elizabeth;
- Sjöberg, Gunnar;
- Cheung, Michael M.H.;
- Weintraub, Robert G.
Publication type:
Article
Adjusting for unmeasured confounding using validation data: Simplified two-stage calibration for survival and dichotomous outcomes.
Published in:
2019
By:
- Hjellvik, Vidar;
- De Bruin, Marie L.;
- Samuelsen, Sven O.;
- Karlstad, Øystein;
- Andersen, Morten;
- Haukka, Jari;
- Vestergaard, Peter;
- Vries, Frank;
- Furu, Kari;
- de Vries, Frank
Publication type:
journal article
The Risk of Colorectal Cancer in Patients With Type 2 Diabetes: Associations With Treatment Stage and Obesity.
Published in:
Diabetes Care, 2015, v. 38, n. 3, p. 495, doi. 10.2337/dc14-1175
By:
- Peeters, Paul J. H. L.;
- Bazelier, Marloes T.;
- Leufkens, Hubert G. M.;
- de Vries, Frank;
- De Bruin, Marie L.
Publication type:
Article
Number of Patients Studied Prior to Approval of New Medicines: A Database Analysis.
Published in:
PLoS Medicine, 2013, v. 10, n. 3, p. 1, doi. 10.1371/journal.pmed.1001407
By:
- Duijnhoven, Ruben G.;
- Straus, Sabine M. J. M.;
- Raine, June M.;
- de Boer, Anthonius;
- Hoes, Arno W.;
- De Bruin, Marie L.
Publication type:
Article
Re: Nonsteroidal Anti-inflammatory Drug Use, Chronic Liver Disease, and Hepatocellular Carcinoma.
Published in:
2013
By:
- Duijnhoven, Ruben G;
- De Bruin, Marie L
Publication type:
Journal Article
Re: Nonsteroidal Anti-inflammatory Drug Use, Chronic Liver Disease, and Hepatocellular Carcinoma.
Published in:
2013
By:
- Duijnhoven, Ruben G;
- De Bruin, Marie L
Publication type:
Letter
Re: Late Effects From Radiation Therapy: The Hits Just Keep on Coming.
Published in:
JNCI: Journal of the National Cancer Institute, 2010, v. 102, n. 8, p. 576, doi. 10.1093/jnci/djq069
By:
- ALEMAN, BERTHE M. P.;
- De BRUIN, MARIE L.;
- DORRESTEIJN, LUCILLE D. A.;
- KROL, AUGUSTINUS D. G.;
- VEER, MARS B. van't;
- BOOGERD, WILLEM;
- VAN LEEUWEN, FLORA E.
Publication type:
Article
Increased Risk of Stroke and Transient Ischemic Attack in 5-Year Survivors of Hodgkin Lymphoma.
Published in:
JNCI: Journal of the National Cancer Institute, 2009, v. 101, n. 13, p. 928, doi. 10.1093/jnci/djp147
By:
- De Bruin, Marie L.;
- Dorresteijn, Lucille D. A.;
- van't Veer, Mars B.;
- Krol, Augustinus D. G.;
- Van der Pal, Helena J.;
- Kappelle, Arnoud C.;
- Boogerd, Willem;
- Aleman, Berthe M. P.;
- Van Leeuwen, Flora E.
Publication type:
Article
Duration of Effectiveness Evaluation of Additional Risk Minimisation Measures for Centrally Authorised Medicinal Products in the EU Between 2012 and 2021.
Published in:
Drug Safety, 2023, v. 46, n. 10, p. 1007, doi. 10.1007/s40264-023-01341-0
By:
- Essink, Sharon C. M.;
- Zomerdijk, Inge M.;
- Straus, Sabine M. J. M.;
- Gardarsdottir, Helga;
- De Bruin, Marie L.
Publication type:
Article
Hydroxyzine Initiation Following Drug Safety Advisories on Cardiac Arrhythmias in the UK and Canada: A Longitudinal Cohort Study.
Published in:
Drug Safety, 2022, v. 45, n. 6, p. 623, doi. 10.1007/s40264-022-01175-2
By:
- Morrow, Richard L.;
- Mintzes, Barbara;
- Souverein, Patrick C.;
- Hallgreen, Christine E.;
- Ahmed, Bilal;
- Roughead, Elizabeth E.;
- De Bruin, Marie L.;
- Kristiansen, Sarah Brøgger;
- Lexchin, Joel;
- Kemp-Casey, Anna;
- Sketris, Ingrid;
- Mangin, Dee;
- Pearson, Sallie-Anne;
- Puil, Lorri;
- Lopert, Ruth;
- Bero, Lisa;
- Gnjidic, Danijela;
- Sarpatwari, Ameet;
- Dormuth, Colin R.
Publication type:
Article
Traceability of Biologics in The Netherlands: An Analysis of Information-Recording Systems in Clinical Practice and Spontaneous ADR Reports.
Published in:
2016
By:
- Klein, Kevin;
- Scholl, Joep;
- Vermeer, Niels;
- Broekmans, André;
- Puijenbroek, Eugène;
- Bruin, Marie;
- Stolk, Pieter;
- Scholl, Joep H G;
- Vermeer, Niels S;
- Broekmans, André W;
- Van Puijenbroek, Eugène P;
- De Bruin, Marie L
Publication type:
journal article
Epidemiology of adverse drug reactions in Europe: a review of recent observational studies.
Published in:
2015
By:
- Bouvy, Jacoline C;
- De Bruin, Marie L;
- Koopmanschap, Marc A
Publication type:
journal article
Incidence of adverse events among healthcare workers following H1N1 Mass immunization in Ghana: a prospective study.
Published in:
2013
By:
- Ankrah, Daniel N A;
- Mantel-Teeuwisse, Aukje K;
- De Bruin, Marie L;
- Amoo, Philip K;
- Ofei-Palm, Charles N;
- Agyepong, Irene;
- Leufkens, Hubert G M
Publication type:
journal article

Found: 44