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Early or late-life treatment with acarbose or rapamycin improves physical performance and affects cardiac structure in aging mice.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2023, v. 78, n. 3, p. 397, doi. 10.1093/gerona/glac221
By:
- Herrera, Jonathan J;
- Pifer, Kaitlyn;
- Louzon, Sean;
- Leander, Danielle;
- Fiehn, Oliver;
- Day, Sharlene M;
- Miller, Richard A;
- Garratt, Michael
Publication type:
Article
Sirtuin 5 levels are limiting in preserving cardiac function and suppressing fibrosis in response to pressure overload.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16506-7
By:
- Guo, Angela H.;
- Baliira, Rachael;
- Skinner, Mary E.;
- Kumar, Surinder;
- Andren, Anthony;
- Zhang, Li;
- Goldsmith, Robert S.;
- Michan, Shaday;
- Davis, Norma J.;
- Maccani, Merissa W.;
- Day, Sharlene M.;
- Sinclair, David A.;
- Brody, Matthew J.;
- Lyssiotis, Costas A.;
- Stein, Adam B.;
- Lombard, David B.
Publication type:
Article
Update on Cardiac Myosin Inhibitors and Potential Role in Treating Obstructive Hypertrophic Cardiomyopathy.
Published in:
2023
By:
- Litt, Michael J.;
- Day, Sharlene M.
Publication type:
Editorial
Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes.
Published in:
2011
By:
- Stein, Adam B.;
- Jones, Thomas A.;
- Herron, Todd J.;
- Patel, Sanjeevkumar R.;
- Day, Sharlene M.;
- Noujaim, Sami F.;
- Milstein, Michelle L.;
- Klos, Matthew;
- Furspan, Philip B.;
- Jalife, José;
- Dressler, Gregory R.;
- Jalife, José
Publication type:
journal article
High‐intensity exercise training using a rotarod instrument (RotaHIIT) significantly improves exercise capacity in mice.
Published in:
Physiological Reports, 2024, v. 12, n. 9, p. 1, doi. 10.14814/phy2.15997
By:
- Herrera, Jonathan J.;
- McAllister, Christopher M.;
- Szczesniak, Danielle;
- Goddard, Rose‐Carmel;
- Day, Sharlene M.
Publication type:
Article
Histidine button engineered into cardiac troponin I protects the ischemic and failing heart.
Published in:
Nature Medicine, 2006, v. 12, n. 2, p. 181, doi. 10.1038/nm1346
By:
- Day, Sharlene M.;
- Westfall, Margaret V.;
- Fomicheva, Ekaterina V.;
- Hoyer, Kirsten;
- Yasuda, Soichiro;
- Cross, Nathan C. La;
- D'Alecy, Louis G.;
- Ingwall, Joanne S.;
- Metzger, Joseph M.
Publication type:
Article
Genetic constraint at single amino acid resolution in protein domains improves missense variant prioritisation and gene discovery.
Published in:
Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01358-9
By:
- Zhang, Xiaolei;
- Theotokis, Pantazis I.;
- Li, Nicholas;
- Ashley, Euan;
- Colan, Steven D.;
- Day, Sharlene M.;
- Helms, Adam;
- Ho, Carolyn Y.;
- Ingles, Jodie;
- Jacoby, Daniel;
- Lakdawala, Neal K.;
- Michels, Michelle;
- Olivotto, Iacopo;
- Owens, Anjali;
- Parikh, Victoria N.;
- Pereira, Alexandre C.;
- Rossano, Joseph;
- Saberi, Sara;
- Semsarian, Chris;
- Wittekind, Samuel
Publication type:
Article
Clinical characteristics and outcomes in childhood-onset hypertrophic cardiomyopathy.
Published in:
European Heart Journal, 2021, v. 42, n. 20, p. 1988, doi. 10.1093/eurheartj/ehab148
By:
- Marston, Nicholas A;
- Han, Larry;
- Olivotto, Iacopo;
- Day, Sharlene M;
- Ashley, Euan A;
- Michels, Michelle;
- Pereira, Alexandre C;
- Ingles, Jodie;
- Semsarian, Christopher;
- Jacoby, Daniel;
- Colan, Steven D;
- Rossano, Joseph W;
- Wittekind, Samuel G;
- Ware, James S;
- Saberi, Sara;
- Helms, Adam S;
- Ho, Carolyn Y
Publication type:
Article
Tuning cardiac performance in ischemic heart disease and failure by modulating myofilament function.
Published in:
Journal of Molecular Medicine, 2007, v. 85, n. 9, p. 911, doi. 10.1007/s00109-007-0181-6
By:
- Day, Sharlene M.;
- Westfall, Margaret V.;
- Metzger, Joseph M.
Publication type:
Article
Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction.
Published in:
Cardiovascular Research, 2008, v. 80, n. 2, p. 209, doi. 10.1093/cvr/cvn198
By:
- Palpant, Nathan J.;
- Day, Sharlene M.;
- Herron, Todd J.;
- Converso, Kimber L.;
- Metzger, Joseph M.
Publication type:
Article
Allelic imbalance and haploinsufficiency in MYBPC3-linked hypertrophic cardiomyopathy.
Published in:
Pflügers Archiv: European Journal of Physiology, 2019, v. 471, n. 5, p. 781, doi. 10.1007/s00424-018-2226-9
By:
- Glazier, Amelia A.;
- Thompson, Andrea;
- Day, Sharlene M.
Publication type:
Article
External validation of the HCM Risk-Kids model for predicting sudden cardiac death in childhood hypertrophic cardiomyopathy.
Published in:
European Journal of Preventive Cardiology, 2022, v. 29, n. 4, p. 678, doi. 10.1093/eurjpc/zwab181
By:
- Norrish, Gabrielle;
- Qu, Chen;
- Field, Ella;
- Cervi, Elena;
- Khraiche, Diala;
- Klaassen, Sabine;
- Ojala, Tiina H;
- Sinagra, Gianfranco;
- Yamazawa, Hirokuni;
- Marrone, Chiara;
- Popoiu, Anca;
- Centeno, Fernando;
- Schouvey, Sylvie;
- Olivotto, Iacopo;
- Day, Sharlene M;
- Colan, Steve;
- Rossano, Joseph;
- Wittekind, Samuel G;
- Saberi, Sara;
- Russell, Mark
Publication type:
Article
Cardiac risks associated with marathon running.
Published in:
2010
By:
- Day, Sharlene M.;
- Thompson, Paul D.
Publication type:
journal article
Cardiovascular health, part 2: sports participation in athletes with cardiovascular conditions.
Published in:
2010
By:
- Baman, Timir S.;
- Gupta, Sanjaya;
- Day, Sharlene M.
Publication type:
journal article
Cardiovascular health, part 1: preparticipation cardiovascular screening.
Published in:
2009
By:
- Gupta, Sanjaya;
- Baman, Timir;
- Day, Sharlene M.
Publication type:
journal article
Dystrophic heart failure blocked by membrane sealant poloxamer.
Published in:
Nature, 2005, v. 436, n. 7053, p. 1025, doi. 10.1038/nature03844
By:
- Yasuda, Soichiro;
- Townsend, DeWayne;
- Michele, Daniel E.;
- Favre, Elizabeth G.;
- Day, Sharlene M.;
- Metzger, Joseph M.
Publication type:
Article
Impact of SARS‐Cov‐2 infection in patients with hypertrophic cardiomyopathy: results of an international multicentre registry.
Published in:
ESC Heart Failure, 2022, v. 9, n. 4, p. 2189, doi. 10.1002/ehf2.13964
By:
- Gimeno, Juan R.;
- Olivotto, Iacopo;
- Rodríguez, Ana Isabel;
- Ho, Carolyn Y.;
- Fernández, Adrián;
- Quiroga, Alejandro;
- Espinosa, Mari Angeles;
- Gómez‐González, Cristina;
- Robledo, María;
- Tojal‐Sierra, Lucas;
- Day, Sharlene M.;
- Owens, Anjali;
- Barriales‐Villa, Roberto;
- Larrañaga, Jose María;
- Rodríguez‐Palomares, Jose;
- González‐del‐Hoyo, Maribel;
- Piqueras‐Flores, Jesús;
- Reza, Nosheen;
- Chumakova, Olga;
- Ashley, Euan A.
Publication type:
Article
Rationale and Design of the ORCCA (Outcomes Registry for Cardiac Conditions in Athletes) Study.
Published in:
Journal of the American Heart Association, 2023, v. 12, n. 11, p. 1, doi. 10.1161/JAHA.122.029052
By:
- Moulson, Nathaniel;
- Petek, Bradley J.;
- Ackerman, Michael J.;
- Churchill, Timothy W.;
- Day, Sharlene M.;
- Kim, Jonathan H.;
- Kliethermes, Stephanie A.;
- Lampert, Rachel;
- Levine, Benjamin D.;
- Martinez, Matthew W.;
- Patel, Manesh R.;
- Phelan, Dermot;
- Harmon, Kimberly G.;
- Baggish, Aaron L.;
- Drezner, Jonathan A.
Publication type:
Article
Sex-Related Differences in Genetic Cardiomyopathies.
Published in:
2022
By:
- Argirò, Alessia;
- Ho, Carolyn;
- Day, Sharlene M.;
- van der Velden, Jolanda;
- Cerbai, Elisabetta;
- Saberi, Sara;
- Tardiff, Jil C.;
- Lakdawala, Neal K.;
- Olivotto, Iacopo
Publication type:
journal article
Genomic Context Differs Between Human Dilated Cardiomyopathy and Hypertrophic Cardiomyopathy.
Published in:
2021
By:
- Puckelwartz, Megan J.;
- Pesce, Lorenzo L.;
- Dellefave-Castillo, Lisa M.;
- Wheeler, Matthew T.;
- Pottinger, Tess D.;
- Robinson, Avery C.;
- Kearns, Samuel D.;
- Gacita, Anthony M.;
- Schoppen, Zachary J.;
- Wenyu Pan;
- Gene Kim;
- Wilcox, Jane E.;
- Anderson, Allen S.;
- Ashley, Euan A.;
- Day, Sharlene M.;
- Cappola, Thomas;
- Dorn II, Gerald W.;
- McNally, Elizabeth M.;
- Pan, Wenyu;
- Kim, Gene
Publication type:
journal article
genome-first approach to rare variants in hypertrophic cardiomyopathy genes MYBPC3 and MYH7 in a medical biobank.
Published in:
Human Molecular Genetics, 2022, v. 31, n. 5, p. 827, doi. 10.1093/hmg/ddab249
By:
- Park, Joseph;
- Packard, Elizabeth A;
- Levin, Michael G;
- Judy, Renae L;
- Center, Regeneron Genetics;
- Damrauer, Scott M;
- Day, Sharlene M;
- Ritchie, Marylyn D;
- Rader, Daniel J
Publication type:
Article
Exercise for Patients With Hypertrophic Cardiomyopathy-Reply.
Published in:
2017
By:
- Saberi, Sara;
- Wheeler, Matthew;
- Day, Sharlene M.
Publication type:
Letter
Effect of Moderate-Intensity Exercise Training on Peak Oxygen Consumption in Patients With Hypertrophic Cardiomyopathy: A Randomized Clinical Trial.
Published in:
2017
By:
- Saberi, Sara;
- Bragg-Gresham, Jennifer;
- Hornsby, Whitney;
- Agarwal, Prachi P.;
- Attili, Anil;
- Concannon, Maryann;
- Kumar, Suwen;
- Herrera, Jonathan;
- Hel, Adam S.;
- Day, Sharlene M.;
- Wheeler, Matthew;
- Dries, Annika M.;
- Shmargad, Yael;
- Salisbury, Heidi;
- Ashley, Euan A.;
- Myers, Jonathan;
- Helms, Adam S;
- Herrera, Jonathan J
Publication type:
journal article
Agonist Activated PKCβ<sub>II</sub> Translocation and Modulation of Cardiac Myocyte Contractile Function.
Published in:
Scientific Reports, 2013, p. 1, doi. 10.1038/srep01971
By:
- Hwang, Hyosook;
- Robinson, Dustin;
- Rogers, Julie B.;
- Stevenson, Tamara K.;
- Lang, Sarah E.;
- Sadayappan, Sakthivel;
- Day, Sharlene M.;
- Sivaramakrishnan, Sivaraj;
- Westfall, Margaret V.
Publication type:
Article
Other side of the coin: the missing heritability in hypertrophic cardiomyopathy.
Published in:
European Heart Journal, 2017, v. 38, n. 46, p. 3469, doi. 10.1093/eurheartj/ehx024
By:
- Helms, Adam S.;
- Day, Sharlene M.
Publication type:
Article
Hypertrophic cardiomyopathy: single gene disease or complex trait?
Published in:
European Heart Journal, 2016, v. 37, n. 23, p. 1823, doi. 10.1093/eurheartj/ehv562
By:
- Helms, Adam S.;
- Day, Sharlene M.
Publication type:
Article
Supercomputing for the parallelization of whole genome analysis.
Published in:
Bioinformatics, 2014, v. 30, n. 11, p. 1508, doi. 10.1093/bioinformatics/btu071
By:
- Puckelwartz, Megan J.;
- Pesce, Lorenzo L.;
- Nelakuditi, Viswateja;
- Dellefave-Castillo, Lisa;
- Golbus, Jessica R.;
- Day, Sharlene M.;
- Cappola, Thomas P.;
- Dorn, Gerald W.;
- Foster, Ian T.;
- McNally, Elizabeth M.
Publication type:
Article
17‐α estradiol ameliorates age‐associated sarcopenia and improves late‐life physical function in male mice but not in females or castrated males.
Published in:
Aging Cell, 2019, v. 18, n. 2, p. N.PAG, doi. 10.1111/acel.12920
By:
- Garratt, Michael;
- Leander, Danielle;
- Pifer, Kaitlyn;
- Bower, Brian;
- Herrera, Jonathan J.;
- Day, Sharlene M.;
- Fiehn, Oliver;
- Brooks, Susan V.;
- Miller, Richard A.
Publication type:
Article
Differential protein expression and basal lamina remodeling in human heart failure.
Published in:
Proteomics - Clinical Applications, 2016, v. 10, n. 5, p. 585, doi. 10.1002/prca.201500099
By:
- Kim, Evelyn H.;
- Galchev, Vladimir I.;
- Kim, Jin Young;
- Misek, Sean A.;
- Stevenson, Tamara K.;
- Campbell, Matthew D.;
- Pagani, Francis D.;
- Day, Sharlene M.;
- Johnson, T. Craig;
- Washburn, Joseph G.;
- Vikstrom, Karen L.;
- Michele, Daniel E.;
- Misek, David E.;
- Westfall, Margaret V.
Publication type:
Article
Quantitative approaches to variant classification increase the yield and precision of genetic testing in Mendelian diseases: the case of hypertrophic cardiomyopathy.
Published in:
Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0616-z
By:
- Walsh, Roddy;
- Mazzarotto, Francesco;
- Whiffin, Nicola;
- Buchan, Rachel;
- Midwinter, William;
- Wilk, Alicja;
- Li, Nicholas;
- Felkin, Leanne;
- Ingold, Nathan;
- Govind, Risha;
- Ahmad, Mian;
- Mazaika, Erica;
- Allouba, Mona;
- Zhang, Xiaolei;
- de Marvao, Antonio;
- Day, Sharlene M.;
- Ashley, Euan;
- Colan, Steven D.;
- Michels, Michelle;
- Pereira, Alexandre C.
Publication type:
Article

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