Works matching AU Dawson, Ted M.

Results: 184
    1

    Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson's Disease: The International Linked Clinical Trials Initiative.

    Published in:
    Journal of Parkinson's Disease, 2024, v. 14, n. 4, p. 657, doi. 10.3233/JPD-230363
    By:
    • Wyse, Richard K.;
    • Isaacs, Tom;
    • Barker, Roger A.;
    • Cookson, Mark R.;
    • Dawson, Ted M.;
    • Devos, David;
    • Dexter, David T.;
    • Duffen, Joy;
    • Federoff, Howard;
    • Fiske, Brian;
    • Foltynie, Thomas;
    • Fox, Susan;
    • Greenamyre, J. Timothy;
    • Kieburtz, Karl;
    • Kordower, Jeffrey H.;
    • Krainc, Dimitri;
    • Matthews, Helen;
    • Moore, Darren J.;
    • Mursaleen, Leah;
    • Schwarzschild, Michael A.
    Publication type:
    Article
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    Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial.

    Published in:
    JAMA Neurology, 2021, v. 78, n. 3, p. 312, doi. 10.1001/jamaneurol.2020.4725
    By:
    • Simuni, Tanya;
    • Fiske, Brian;
    • Merchant, Kalpana;
    • Coffey, Christopher S.;
    • Klingner, Elizabeth;
    • Caspell-Garcia, Chelsea;
    • Lafontant, David-Erick;
    • Matthews, Helen;
    • Wyse, Richard K.;
    • Brundin, Patrik;
    • Simon, David K.;
    • Schwarzschild, Michael;
    • Weiner, David;
    • Adams, Jamie;
    • Venuto, Charles;
    • Dawson, Ted M.;
    • Baker, Liana;
    • Kostrzebski, Melissa;
    • Ward, Tina;
    • Rafaloff, Gary
    Publication type:
    Article
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    Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease.

    Published in:
    JAMA Neurology, 2016, v. 73, n. 10, p. 1217, doi. 10.1001/jamaneurol.2016.2245
    By:
    • Davis, Marie Y.;
    • Johnson, Catherine O.;
    • Leverenz, James B.;
    • Weintraub, Daniel;
    • Trojanowski, John Q.;
    • Chen-Plotkin, Alice;
    • Van Deerlin, Vivianna M.;
    • Quinn, Joseph F.;
    • Chung, Kathryn A.;
    • Peterson-Hiller, Amie L.;
    • Rosenthal, Liana S.;
    • Dawson, Ted M.;
    • Albert, Marilyn S.;
    • Goldman, Jennifer G.;
    • Stebbins, Glenn T.;
    • Bernard, Bryan;
    • Wszolek, Zbigniew K.;
    • Ross, Owen A.;
    • Dickson, Dennis W.;
    • Eidelberg, David
    Publication type:
    Article
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    Ironing out tau's role in parkinsonism.

    Published in:
    Nature Medicine, 2012, v. 18, n. 2, p. 197, doi. 10.1038/nm.2668
    By:
    • Stankowski, Jeannette N;
    • Dawson, Valina L;
    • Dawson, Ted M
    Publication type:
    Article
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    Taming the clot-buster tPA.

    Published in:
    Nature Medicine, 2006, v. 12, n. 9, p. 993, doi. 10.1038/nm0906-993
    By:
    • Dawson, Ted M.;
    • Dawson, Valina L.
    Publication type:
    Article
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    New insights into Parkinson’s disease.

    Published in:
    Journal of Neurology, 2003, v. 250, p. iii15, doi. 10.1007/s00415-003-1304-9
    By:
    • Chung, Kenny K. K.;
    • Dawson, Valina L.;
    • Dawson, Ted M.
    Publication type:
    Article
    18

    The NINDS Parkinson's disease biomarkers program.

    Published in:
    2016
    By:
    • Rosenthal, Liana S.;
    • Drake, Daniel;
    • Alcalay, Roy N.;
    • Babcock, Debra;
    • Bowman, F. DuBois;
    • Chen‐Plotkin, Alice;
    • Dawson, Ted M.;
    • Dewey, Richard B.;
    • German, Dwight C.;
    • Huang, Xuemei;
    • Landin, Barry;
    • McAuliffe, Matthew;
    • Petyuk, Vladislav A.;
    • Scherzer, Clemens R.;
    • Hillaire‐Clarke, Coryse St.;
    • Sieber, Beth‐Anne;
    • Sutherland, Margaret;
    • Tarn, Chi;
    • West, Andrew;
    • Vaillancourt, David
    Publication type:
    journal article
    19

    Absence of C9ORF72 expanded or intermediate repeats in autopsy-confirmed Parkinson's disease.

    Published in:
    Movement Disorders, 2014, v. 29, n. 6, p. 827, doi. 10.1002/mds.25838
    By:
    • Nuytemans, Karen;
    • Inchausti, Vanessa;
    • Beecham, Gary W.;
    • Wang, Liyong;
    • Dickson, Dennis W.;
    • Trojanowski, John Q.;
    • Lee, Virginia M.‐Y.;
    • Mash, Deborah C.;
    • Frosch, Matthew P.;
    • Foroud, Tatiana M.;
    • Honig, Lawrence S.;
    • Montine, Thomas J.;
    • Dawson, Ted M.;
    • Martin, Eden R.;
    • Scott, William K.;
    • Vance, Jeffery M.
    Publication type:
    Article
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    Alpha-synuclein and Parkinson's disease: Implications from the screening of more than 1,900 patients.

    Published in:
    Movement Disorders, 2005, v. 20, n. 9, p. 1191, doi. 10.1002/mds.20504
    By:
    • Berg, Daniela;
    • Niwar, Marc;
    • Maass, Sylvia;
    • Zimprich, Alexander;
    • Möller, J. Carsten;
    • Wuellner, Ullrich;
    • Schmitz-Hübsch, Tanja;
    • Klein, Christine;
    • Tan, Eng-King;
    • Schöls, Ludger;
    • Marsh, Laura;
    • Dawson, Ted M.;
    • Janetzky, Bernd;
    • Müller, Thomas;
    • Woitalla, Dirk;
    • Kostic, Vladimir;
    • Pramstaller, Peter P.;
    • Oertel, Wolfgang H.;
    • Bauer, Peter;
    • Krueger, Rejko
    Publication type:
    Article
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    Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease.

    Published in:
    Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01180-z
    By:
    • Park, Jong-Sung;
    • Kam, Tae-In;
    • Lee, Saebom;
    • Park, Hyejin;
    • Oh, Yumin;
    • Kwon, Seung-Hwan;
    • Song, Jae-Jin;
    • Kim, Donghoon;
    • Kim, Hyunhee;
    • Jhaldiyal, Aanishaa;
    • Na, Dong Hee;
    • Lee, Kang Choon;
    • Park, Eun Ji;
    • Pomper, Martin G.;
    • Pletnikova, Olga;
    • Troncoso, Juan C.;
    • Ko, Han Seok;
    • Dawson, Valina L.;
    • Dawson, Ted M.;
    • Lee, Seulki
    Publication type:
    Article
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    AAA + ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 1.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32365-2
    By:
    • Umanah, George K. E.;
    • Abalde-Atristain, Leire;
    • Khan, Mohammed Repon;
    • Mitra, Jaba;
    • Dar, Mohamad Aasif;
    • Chang, Melissa;
    • Tangella, Kavya;
    • McNamara, Amy;
    • Bennett, Samuel;
    • Chen, Rong;
    • Aggarwal, Vasudha;
    • Cortes, Marisol;
    • Worley, Paul F.;
    • Ha, Taekjip;
    • Dawson, Ted M.;
    • Dawson, Valina L.
    Publication type:
    Article
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    Accumulation of the Authentic Parkin Substrate Aminoacyl-tRNA Synthetase Cofactor, p38/JTV-1, Leads to Catecholaminergic Cell Death.

    Published in:
    Journal of Neuroscience, 2005, v. 25, n. 35, p. 7968, doi. 10.1523/JNEUROSCI.2172-05.2005
    By:
    • Han Seok Ko;
    • Von Coelln, Rainer;
    • Sriram, Sathya R.;
    • Seong Who Kim;
    • Chung, Kenny K. K.;
    • Pletnikova, Olga;
    • Troncoso, Juan;
    • Johnson, Brett;
    • Saffary, Roya;
    • Goh, Eyleen L.;
    • Hongjun Song;
    • Bum-Joon Park;
    • Min Jung Kim;
    • Sunghoon Kim;
    • Dawson, Valina L.;
    • Dawson, Ted M.
    Publication type:
    Article
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    Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.

    Published in:
    2018
    By:
    • Berger, Nathan A.;
    • Besson, Valerie C.;
    • Boulares, A. Hamid;
    • Bürkle, Alexander;
    • Chiarugi, Alberto;
    • Clark, Robert S.;
    • Curtin, Nicola J.;
    • Cuzzocrea, Salvatore;
    • Dawson, Ted M.;
    • Dawson, Valina L.;
    • Haskó, György;
    • Liaudet, Lucas;
    • Moroni, Flavio;
    • Pacher, Pál;
    • Radermacher, Peter;
    • Salzman, Andrew L.;
    • Snyder, Solomon H.;
    • Soriano, Francisco Garcia;
    • Strosznajder, Robert P.;
    • Sümegi, Balázs
    Publication type:
    journal article
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    Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson's disease.

    Published in:
    Science Translational Medicine, 2023, v. 15, n. 724, p. 1, doi. 10.1126/scitranslmed.add0499
    By:
    • Khan, Mohammed Repon;
    • Yin, Xiling;
    • Kang, Sung-Ung;
    • Mitra, Jaba;
    • Wang, Hu;
    • Ryu, Taekyung;
    • Brahmachari, Saurav;
    • Karuppagounder, Senthilkumar S.;
    • Kimura, Yasuyoshi;
    • Jhaldiyal, Aanishaa;
    • Kim, Hyun Hee;
    • Gu, Hao;
    • Chen, Rong;
    • Redding-Ochoa, Javier;
    • Troncoso, Juan;
    • Na, Chan Hyun;
    • Ha, Taekjip;
    • Dawson, Valina L.;
    • Dawson, Ted M.
    Publication type:
    Article
    49

    The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease.

    Published in:
    Science Translational Medicine, 2023, v. 15, n. 679, p. 1, doi. 10.1126/scitranslmed.abp9352
    By:
    • Karuppagounder, Senthilkumar S.;
    • Wang, Hu;
    • Kelly, Terence;
    • Rush, Roger;
    • Nguyen, Richard;
    • Bisen, Shivani;
    • Yamashita, Yoko;
    • Sloan, Nicholas;
    • Dang, Brianna;
    • Sigmon, Alexander;
    • Lee, Hyeun Woo;
    • Marino Lee, Shirley;
    • Watkins, Leslie;
    • Kim, Erica;
    • Brahmachari, Saurav;
    • Kumar, Manoj;
    • Werner, Milton H.;
    • Dawson, Ted M.;
    • Dawson, Valina L.
    Publication type:
    Article
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