Works matching AU Davidson, Beverly L.

Results: 107

Functional Repair of Human Donor Lungs by IL-10 Gene Therapy.

Published in:

Science Translational Medicine, 2009, v. 1, n. 4, p. 1, doi. 10.1126/scitranslmed.3000266

By:

Cypel, Marcelo;
Liu, Mingyao;
Rubacha, Matt;
Yeung, Jonathan C.;
Hirayama, Shin;
Anraku, Masaki;
Sato, Masaaki;
Medin, Jeffrey;
Davidson, Beverly L.;
Perrot, Marc de;
Waddell, Thomas K.;
Slutsky, Arthur S.;
Keshavjee, Shaf

Publication type:

Article

Huntington's disease phenotypes are improved via mTORC1 modulation by small molecule therapy.

Published in:

PLoS ONE, 2022, v. 17, n. 8, p. 1, doi. 10.1371/journal.pone.0273710

By:

St-Cyr, Sophie;
Child, Daniel D.;
Giaime, Emilie;
Smith, Alicia R.;
Pascua, Christine J.;
Hahm, Seung;
Saiah, Eddine;
Davidson, Beverly L.

Publication type:

Article

Corrigendum: All in the RNA family.

Published in:

2006

By:

Davidson, Beverly L.

Publication type:

Correction Notice

All in the RNA family.

Published in:

Nature Biotechnology, 2006, v. 24, n. 8, p. 951, doi. 10.1038/nbt0806-951

By:

Davidson, Beverly L.

Publication type:

Article

siRNA-mediated gene silencing in vitro and in vivo.

Published in:

Nature Biotechnology, 2002, v. 20, n. 10, p. 1006, doi. 10.1038/nbt739

By:

Xia, Haibin;
Mao, Qinwen;
Paulson, Henry L;
Davidson, Beverly L

Publication type:

Article

The HIV Tat protein transduction domain improves the biodistribution of β-glucuronidase expressed from recombinant viral vectors.

Published in:

Nature Biotechnology, 2001, v. 19, n. 7, p. 640, doi. 10.1038/90242

By:

Xia, Haibin;
Mao, Qinwen;
Davidson, Beverly L.

Publication type:

Article

Transvascular delivery of small interfering RNA to the central nervous system.

Published in:

Nature, 2007, v. 448, n. 7149, p. 39, doi. 10.1038/nature05901

By:

Kumar, Priti;
Wu, Haoquan;
McBride, Jodi L.;
Kyeong-Eun Jung;
Moon Hee Kim;
Davidson, Beverly L.;
Sang Kyung Lee;
Shankar, Premlata;
Manjunath, N.

Publication type:

Article

Viral-Mediated Gene Transfer to Mouse Primary Neural Progenitor Cells

Published in:

Molecular Therapy, 2002, v. 5, n. 1, p. 16, doi. 10.1006/mthe.2001.0512

By:

Hughes, Stephanie M.;
Moussavi-Harami, Farid;
Sauter, Sybille L.;
Davidson, Beverly L.

Publication type:

Article

siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 1, p. e9, doi. 10.1093/nar/gks797

By:

Boudreau, Ryan L.;
Spengler, Ryan M.;
Hylock, Ray H.;
Kusenda, Brandyn J.;
Davis, Heather A.;
Eichmann, David A.;
Davidson, Beverly L.

Publication type:

Article

Targeting Alzheimer’s disease genes with RNA interference: an efficient strategy for silencing mutant alleles.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 2, p. 661, doi. 10.1093/nar/gkh208

By:

Miller, Victor M.;
Gouvion, Cynthia M.;
Davidson, Beverly L.;
Paulson, Henry L.

Publication type:

Article

An orally available, brain penetrant, small molecule lowers huntingtin levels by enhancing pseudoexon inclusion.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28653-6

By:

Keller, Caroline Gubser;
Shin, Youngah;
Monteys, Alex Mas;
Renaud, Nicole;
Beibel, Martin;
Teider, Natalia;
Peters, Thomas;
Faller, Thomas;
St-Cyr, Sophie;
Knehr, Judith;
Roma, Guglielmo;
Reyes, Alejandro;
Hild, Marc;
Lukashev, Dmitriy;
Theil, Diethilde;
Dales, Natalie;
Cha, Jang-Ho;
Borowsky, Beth;
Dolmetsch, Ricardo;
Davidson, Beverly L.

Publication type:

Article

A Knock-In Reporter Model of Batten Disease.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 37, p. 9826, doi. 10.1523/JNEUROSCI.1710-07.2007

By:

Eliason, Steven L.;
Stein, Colleen S.;
Qinwen Mao;
Tecedor, Luis;
Song-Lin Ding;
Gaines, D. Meredith;
Davidson, Beverly L.

Publication type:

Article

Connecdenn, A Novel DENN Domain-Containing Protein of Neuronal Clathrin-Coated Vesicles Functioning in Synaptic Vesicle Endocytosis.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 51, p. 13202, doi. 10.1523/JNEUROSCI.4608-06.2006

By:

Allaire, Patrick D.;
Ritter, Brigitte;
Thomas, Sebastien;
Burman, Jonathon L.;
Denisov, Alexei Yu.;
Legendre-Guillemin, Valerie;
Harper, Scott Q.;
Davidson, Beverly L.;
Gehring, Kalle;
McPherson, Peter S.

Publication type:

Article

Intracranial Delivery of CLN2 Reduces Brain Pathology in a Mouse Model of Classical Late Infantile Neuronal Ceroid Lipofuscinosis.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 5, p. 1334, doi. 10.1523/JNEUROSCI.2676-05.2006

By:

Passini, Marco A.;
Dodge, James C.;
Bu, Jie;
Yang, Wendy;
Qi Zhao;
Sondhi, Dolan;
Hackett, Neil R.;
Kaminsky, Stephen M.;
Qinwen Mao;
Shihabuddin, Lamya S.;
Cheng, Seng H.;
Sleat, David E.;
Stewart, Gregory R.;
Davidson, Beverly L.;
Lobel, Peter;
Crystal, Ronald G.

Publication type:

Article

Silencing Primary Dystonia: Lentiviral-Mediated RNA Interference Therapy for DYT1 Dystonia.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 45, p. 10502, doi. 10.1523/JNEUROSCI.3016-05.2005

By:

Gonzalez-Alegre, Pedro;
Bode, Nicole;
Davidson, Beverly L.;
Paulson, Henry L.

Publication type:

Article

Functional Correction of CNS Phenotypes in a Lysosomal Storage Disease Model Using Adeno-Associated Virus Type 4 Vectors.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 41, p. 9321, doi. 10.1523/JNEUROSCI.2936-05.2005

By:

Gumei Liu;
Martins, Inês;
Wemmie, John A.;
Chiorini, John A.;
Davidson, Beverly L.

Publication type:

Article

CHIP Suppresses Polyglutamine Aggregation and Toxicity In Vitro and In Vivo.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 40, p. 9152, doi. 10.1523/JNEUROSCI.3001-05.2005

By:

Miller, Victor M.;
Nelson, Rick F.;
Gouvion, Cynthia M.;
Williams, Aislinn;
Rodriguez-Lebron, Edgardo;
Harper, Scott Q.;
Davidson, Beverly L.;
Rebagliati, Michael R.;
Paulson, Henry L.

Publication type:

Article

A Mouse Model of Classical Late-Infantile Neuronal Ceroid Lipofuscinosis Based on Targeted Disruption of the CLN2 Gene Results in a Loss of Tripeptidyl-Peptidase I Activity and Progressive Neurodegeneration.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 41, p. 9117, doi. 10.1523/JNEUROSCI.2729-04.2004

By:

Sleat, David E.;
Wiseman, Jennifer A.;
El-Banna, Mukarram;
Kwi-Hye Kim;
Qinwen Mao;
Price, Sandy;
Macauley, Shannon L.;
Sidman, Richard L.;
Shen, Michael M.;
Qi Zhao;
Passini, Marco A.;
Davidson, Beverly L.;
Stewart, Gregory R.;
Lobel, Peter

Publication type:

Article

Impact of Human Interleukin-10 on Vector-Induced Inflammation and Early Graft Function in Rat Lung Transplantation.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2003, v. 28, n. 5, p. 616, doi. 10.1165/rcmb.2002-0109OC

By:

de Perrot, Marc;
Fischer, Stefan;
Mingyao Liu;
Yumiko Imai;
Martins, Saulo;
Shoji Sakiyama;
Toshi Tabata;
Xiao-Hui Bai;
Waddell, Thomas K.;
Davidson, Beverly L.;
Keshavjee, Shaf

Publication type:

Article

Increasing Epithelial Junction Permeability Enhances Gene Transfer to Airway Epithelia In Vivo.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2000, v. 22, n. 2, p. 129, doi. 10.1165/ajrcmb.22.2.3938

By:

Wang, Guoshun;
Zabner, Joseph;
Deering, Camille;
Launspach, Jan;
Shao, Jianqiang;
Bodner, Mordechai;
Jolly, Doug J.;
Davidson, Beverly L.;
McCray Jr., Paul B.

Publication type:

Article

Diverse Splicing Patterns of Exonized Alu Elements in Human Tissues.

Published in:

PLoS Genetics, 2008, v. 4, n. 10, p. 1, doi. 10.1371/journal.pgen.1000225

By:

Lan Lin;
Shihao Shen;
Anne Tye;
Cai, James J.;
Peng Jiang;
Davidson, Beverly L.;
Yi Xing

Publication type:

Article

Immortalized striatal precursor neurons from Huntington’s disease patient-derived iPS cells as a platform for target identification and screening for experimental therapeutics.

Published in:

Human Molecular Genetics, 2021, v. 30, n. 24, p. 2469, doi. 10.1093/hmg/ddab200

By:

Akimov, Sergey S.;
Mali Jiang;
Kedaigle, Amanda J.;
Arbez, Nicolas;
Marque, Leonard O.;
Eddings, Chelsy R.;
Ranum, Paul T.;
Whelan, Emma;
Tang, Anthony;
Wang, Ronald;
DeVine, Lauren R.;
Talbot Jr., Conover C.;
Cole, Robert N.;
Ratovitski, Tamara;
Davidson, Beverly L.;
Fraenkel, Ernest;
Ross, Christopher A.

Publication type:

Article

RNA Interference of Human α-Synuclein in Mouse.

Published in:

Frontiers in Neurology, 2017, v. 8, p. 1, doi. 10.3389/fneur.2017.00013

By:

Young-Cho Kim;
Miller, Adam;
Lins, Livia C. R. F.;
Sang-Woo Han;
Keiser, Megan S.;
Boudreau, Ryan L.;
Davidson, Beverly L.;
Narayanan, Nandakumar S.

Publication type:

Article

The limitations of central nervous systemdirected gene transfer.

Published in:

Behavioral & Brain Sciences, 1995, v. 18, n. 1, p. 54, doi. 10.1017/S0140525X0003733X

By:

Davidson, Beverly L.

Publication type:

Article

An AAV variant selected through NHP screens robustly transduces the brain and drives secreted protein expression in NHPs and mice.

Published in:

Science Translational Medicine, 2025, v. 17, n. 798, p. 1, doi. 10.1126/scitranslmed.adr2531

By:

Tecedor, Luis;
Chen, Yong Hong;
Leib, David E.;
Ranum, Paul T.;
Keiser, Megan S.;
Lewandowski, Brian C.;
Carrell, Elli M.;
Lysenko, Elena;
Huerta-Ocampo, Icnelia;
Arora, Sakshi;
Cheng, Congsheng;
Liu, Xueyuan;
Davidson, Beverly L.

Publication type:

Article

Ultrasound-guided gene transfer to hepatocytes in utero.

Published in:

1998

By:

Wang, Guoshun;
Williamson, Roger;
Mueller, Glenda;
Thomas, Patricia;
Davidson, Beverly L.;
McCray, Jr, Paul B.;
Wang, G;
Williamson, R;
Mueller, G;
Thomas, P;
Davidson, B L;
McCray, P B Jr

Publication type:

journal article

Non-secretion of mutant proteins of the glaucoma gene myocilin in cultured trabecular meshwork cells and in aqueous humor.

Published in:

Human Molecular Genetics, 2001, v. 10, n. 2, p. 117, doi. 10.1093/hmg/10.2.117

By:

Jacobson, Nasreen;
Andrews, Michael;
Shepard, Allan R.;
Nishimura, Darryl;
Searby, Charles;
Fingert, John H.;
Hageman, Greg;
Mullins, Robert;
Davidson, Beverly L.;
Kwon, Young H.;
Alward, W. L. M.;
Stone, Edwin M.;
Clark, Abbot F.;
Sheffield, Val C.

Publication type:

Article

Batten disease: evaluation of CLN3 mutations on protein localization and function.

Published in:

Human Molecular Genetics, 2000, v. 9, n. 5, p. 735, doi. 10.1093/hmg/9.5.735

By:

Haskell, Ronald E.;
Carr, Carrie J.;
Pearce, David A.;
Bennett, Michael J.;
Davidson, Beverly L.

Publication type:

Article

Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching.

Published in:

Nature Communications, 2023, p. 1, doi. 10.1038/s41467-023-38273-3

By:

Dawicki-McKenna, Jennine M.;
Felix, Alex J.;
Waxman, Elisa A.;
Cheng, Congsheng;
Amado, Defne A.;
Ranum, Paul T.;
Bogush, Alexey;
Dungan, Lea V.;
Maguire, Jean Ann;
Gagne, Alyssa L.;
Heller, Elizabeth A.;
French, Deborah L.;
Davidson, Beverly L.;
Prosser, Benjamin L.

Publication type:

Article

AAV gene transfer delays disease onset in a TPP1-deficient canine model of the late infantile form of Batten disease.

Published in:

Science Translational Medicine, 2015, v. 7, n. 313, p. 1, doi. 10.1126/scitranslmed.aac6191

By:

Katz, Martin L.;
Tecedor, Luis;
Yonghong Chen;
Williamson, Baye G.;
Lysenko, Elena;
Wininger, Fred A.;
Young, Whitney M.;
Johnson, Gayle C.;
Whiting, Rebecca E. H.;
Coates, Joan R.;
Davidson, Beverly L.

Publication type:

Article

Gene Transfer of Human Apoe Isoforms Results in Differential Modulation of Amyloid Deposition and Neurotoxicity in Mouse Brain.

Published in:

Science Translational Medicine, 2013, v. 5, n. 212, p. 1, doi. 10.1126/scitranslmed.3007000

By:

Hudry, Eloise;
Dashkoff, Jonathan;
Roe, Alysson D.;
Takeda, Shuko;
Koffie, Robert M.;
Hashimoto, Tadafumi;
Scheel, Maria;
Spires-Jones, Tara;
Arbel-Ornath, Michal;
Betensky, Rebecca;
Davidson, Beverly L.;
Hyman, Bradley T.

Publication type:

Article

CLN3 Loss Disturbs Membrane Microdomain Properties and Protein Transport in Brain Endothelial Cells.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 46, p. 18065, doi. 10.1523/JNEUROSCI.0498-13.2013

By:

Tecedor, Luis;
Stein, Colleen S.;
Schultz, Mark L.;
Farwanah, Hany;
Sandhoff, Konrad;
Davidson, Beverly L.

Publication type:

Article

The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 53, p. 14341, doi. 10.1523/JNEUROSCI.2390-08.2008

By:

Packer, Amy N.;
Yi Xing;
Harper, Scott Q.;
Jones, Lesley;
Davidson, Beverly L.

Publication type:

Article

Restoring Acid-Sensing Ion Channel-1a in the Amygdala of Knock-Out Mice Rescues Fear Memory But Not Unconditioned Fear Responses.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 51, p. 13737, doi. 10.1523/JNEUROSCI.3907-08.2008

By:

Coryell, Matthew W.;
Wunsch, Amanda M.;
Haenfler, Jill M.;
Allen, Jason E.;
McBride, Jodi L.;
Davidson, Beverly L.;
Wemmie, John A.

Publication type:

Article

Toward therapy for DYT1 dystonia: Allele-specific silencing of mutant TorsinA.

Published in:

Annals of Neurology, 2003, v. 53, n. 6, p. 781

By:

Pedro Gonzalez-Alegre;
Victor M. Miller;
Beverly L. Davidson;
Henry L. Paulson

Publication type:

Article

Current prospects for RNA interference-based therapies.

Published in:

Nature Reviews Genetics, 2011, v. 12, n. 5, p. 329, doi. 10.1038/nrg2968

By:

Davidson, Beverly L.;
McCray, Paul B.

Publication type:

Article

DeepRepeat: direct quantification of short tandem repeats on signal data from nanopore sequencing.

Published in:

Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-022-02670-6

By:

Fang, Li;
Liu, Qian;
Monteys, Alex Mas;
Gonzalez-Alegre, Pedro;
Davidson, Beverly L.;
Wang, Kai

Publication type:

Article

Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease

Published in:

FEBS Letters, 2003, v. 555, n. 2, p. 351, doi. 10.1016/S0014-5793(03)01274-2

By:

Mao, Qinwen;
Xia, Haibin;
Davidson, Beverly L.

Publication type:

Article

Membrane topology of CLN3, the protein underlying Batten disease

Published in:

FEBS Letters, 2003, v. 541, n. 1-3, p. 40, doi. 10.1016/S0014-5793(03)00284-9

By:

Mao, Qinwen;
Foster, Brian J.;
Xia, Haibin;
Davidson, Beverly L.

Publication type:

Article

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

Published in:

Nature Medicine, 2004, v. 10, n. 8, p. 816, doi. 10.1038/nm1076

By:

Haibin Xia;
Qinwen Mao;
Eliason, Steven L.;
Harper, Scott Q.;
Martins, In&eacirc;s H.;
Orr, Harry T.;
Paulson, Henry L.;
Yang, Linda;
Kotin, Robert M.;
Davidson, Beverly L.

Publication type:

Article

Identification of PDGFR as a receptor for AAV-5 transduction.

Published in:

Nature Medicine, 2003, v. 9, n. 10, p. 1306, doi. 10.1038/nm929

By:

Di Pasquale, Giovanni;
Davidson, Beverly L.;
Stein, Colleen S.;
Martins, Inês;
Scudiero, Dominic;
Monks, Anne;
Chiorini, John A.

Publication type:

Article

Adenoviral Gene Transfer Restores Lysyl Hydroxylase Activity in Type VI Ehlers-Danlos Syndrome.

Published in:

Journal of Investigative Dermatology, 2001, v. 116, n. 4, p. 602, doi. 10.1046/j.1523-1747.2001.01300.x

By:

Rauma, Tanja;
Kumpumäki, Sanna;
Anderson, Richard;
Davidson, Beverly L.;
Ruotsalainen, Heli;
Myllylä, Raili;
Hautala, Timo

Publication type:

Article

Nonallele Specific Silencing of Ataxin-7 Improves Disease Phenotypes in a Mouse Model of SCA7.

Published in:

Molecular Therapy, 2014, v. 22, n. 9, p. 1635, doi. 10.1038/mt.2014.108

By:

Ramachandran, Pavitra S;
Boudreau, Ryan L;
Schaefer, Kellie A;
La Spada, Albert R;
Davidson, Beverly L

Publication type:

Article

Broad Therapeutic Benefit After RNAi Expression Vector Delivery to Deep Cerebellar Nuclei: Implications for Spinocerebellar Ataxia Type 1 Therapy.

Published in:

Molecular Therapy, 2014, v. 22, n. 3, p. 588, doi. 10.1038/mt.2013.279

By:

Keiser, Megan S;
Boudreau, Ryan L;
Davidson, Beverly L

Publication type:

Article

Toward RNAi Therapy for the Polyglutamine Disease Machado-Joseph Disease.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1898, doi. 10.1038/mt.2013.144

By:

do Carmo Costa, Maria;
Luna-Cancalon, Katiuska;
Fischer, Svetlana;
Ashraf, Naila S;
Ouyang, Michelle;
Dharia, Rahil M;
Martin-Fishman, Lucas;
Yang, Yemen;
Shakkottai, Vikram G;
Davidson, Beverly L;
Rodríguez-Lebrón, Edgardo;
Paulson, Henry L

Publication type:

Article

Silencing Mutant ATXN3 Expression Resolves Molecular Phenotypes in SCA3 Transgenic Mice.

Published in:

Molecular Therapy, 2013, v. 21, n. 10, p. 1909, doi. 10.1038/mt.2013.152

By:

Rodríguez-Lebrón, Edgardo;
Costa, Maria doCarmo;
Luna-Cancalon, Katiuska;
Peron, Therese M;
Fischer, Svetlana;
Boudreau, Ryan L;
Davidson, Beverly L;
Paulson, Henry L

Publication type:

Article

Taking a Break From Huntingtin.

Published in:

Molecular Therapy, 2012, v. 20, n. 10, p. 1838, doi. 10.1038/mt.2012.191

By:

Davidson, Beverly L

Publication type:

Article

Sialic Acid Deposition Impairs the Utility of AAV9, but Not Peptide-modified AAVs for Brain Gene Therapy in a Mouse Model of Lysosomal Storage Disease.

Published in:

Molecular Therapy, 2012, v. 20, n. 7, p. 1393, doi. 10.1038/mt.2012.100

By:

Chen, Yong Hong;
Claflin, Kristin;
Geoghegan, James C;
Davidson, Beverly L

Publication type:

Article

Rational Design of Therapeutic siRNAs: Minimizing Off-targeting Potential to Improve the Safety of RNAi Therapy for Huntington's Disease.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2169, doi. 10.1038/mt.2011.185

By:

Boudreau, Ryan L;
Spengler, Ryan M;
Davidson, Beverly L

Publication type:

Article

Preclinical Safety of RNAi-Mediated HTT Suppression in the Rhesus Macaque as a Potential Therapy for Huntington's Disease.

Published in:

Molecular Therapy, 2011, v. 19, n. 12, p. 2152, doi. 10.1038/mt.2011.219

By:

McBride, Jodi L;
Pitzer, Mark R;
Boudreau, Ryan L;
Dufour, Brett;
Hobbs, Theodore;
Ojeda, Sergio R;
Davidson, Beverly L

Publication type:

Article