Works by David J. Greenblatt

Results: 340

The Persistent Ambiguity of Adverse Drug Reactions.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 6, p. 1533, doi. 10.1002/cpt.3665

By:

Sellers, Edward M.;
Greenblatt, David J.

Publication type:

Article

Mechanism of dasabuvir inhibition of acetaminophen glucuronidation.

Published in:

Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 1, p. 131, doi. 10.1093/jpp/rgab144

By:

Zhang, Qingchen;
Duan, Su Xiang;
Harmatz, Jerold S;
Wei, Zixuan;
Singleton, Christopher A;
Greenblatt, David J

Publication type:

Article

Prolonged therapy with the anticonvulsant carbamazepine leads to increased plasma clearance of fentanyl.

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 6, p. 982, doi. 10.1111/jphp.13079

By:

Nozari, Ala;
Akeju, Oluwaseun;
Mirzakhani, Hooman;
Eskandar, Emad;
Ma, Zhijun;
Hossain, MD Amin;
Wang, Qingping;
Greenblatt, David J.;
Martyn, J. A. Jeevendra

Publication type:

Article

Resveratrol glucuronidation in vitro: potential implications of inhibition by probenecid.

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 3, p. 371, doi. 10.1111/jphp.13037

By:

Matin, Bahar;
Sherbini, Ahmad A.;
Alam, Novera;
Harmatz, Jerold S.;
Greenblatt, David J.

Publication type:

Article

Inhibition of human cytochromes P450 in vitro by ritonavir and cobicistat.

Published in:

Journal of Pharmacy & Pharmacology, 2017, v. 69, n. 12, p. 1786, doi. 10.1111/jphp.12820

By:

Hossain, Md Amin;
Tran, Timothy;
Chen, Tianmeng;
Mikus, Gerd;
Greenblatt, David J.

Publication type:

Article

Mechanism of in-vitro inhibition of UGT1A1 by paritaprevir.

Published in:

Journal of Pharmacy & Pharmacology, 2017, v. 69, n. 12, p. 1794, doi. 10.1111/jphp.12821

By:

Alam, Novera;
Angeli, Mia G.;
Greenblatt, David J.

Publication type:

Article

Metabolic interactions between acetaminophen (paracetamol) and two flavonoids, luteolin and quercetin, through in-vitro inhibition studies.

Published in:

Journal of Pharmacy & Pharmacology, 2017, v. 69, n. 12, p. 1762, doi. 10.1111/jphp.12812

By:

Cao, Lei;
Kwara, Awewura;
Greenblatt, David J.

Publication type:

Article

Pharmacokinetics cannot explain the increased effective dose requirement for morphine and midazolam in rats during their extended administration alone or in combination.

Published in:

Journal of Pharmacy & Pharmacology, 2017, v. 69, n. 1, p. 82, doi. 10.1111/jphp.12663

By:

Schaller, Stefan J.;
Alam, Saad M.;
Mao, Jianren;
Zhao, Yanli;
Blobner, Manfred;
Greenblatt, David J.;
Martyn, J.A. Jeevendra

Publication type:

Article

Inhibition of 2-methoxyestradiol glucuronidation by probenecid.

Published in:

Journal of Pharmacy & Pharmacology, 2015, v. 67, n. 11, p. 1585, doi. 10.1111/jphp.12462

By:

Qian, Yuli;
Sherbini, Ahmad;
Matin, Bahar;
Zhao, Yanli;
Castellot, John;
Greenblatt, David J.

Publication type:

Article

Evidence for regulation of UDP-glucuronosyltransferase ( UGT) 1 A1 protein expression and activity via DNA methylation in healthy human livers.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 6, p. 874, doi. 10.1111/jphp.12053

By:

Yasar, Umit;
Greenblatt, David J.;
Guillemette, Chantal;
Court, Michael H.

Publication type:

Article

Mechanism of cytochrome P450-3A inhibition by ketoconazole.

Published in:

Journal of Pharmacy & Pharmacology, 2011, v. 63, n. 2, p. 214, doi. 10.1111/j.2042-7158.2010.01202.x

By:

Greenblatt, David J.;
Zhao, Yanli;
Venkatakrishnan, Karthik;
Duan, Su X.;
Harmatz, Jerold S.;
Parent, Sarah J.;
Court, Michael H.;
von Moltke, Lisa L.

Publication type:

Article

Induction of P-glycoprotein expression and activity by ritonavir in bovine brain microvessel endothelial cells.

Published in:

Journal of Pharmacy & Pharmacology, 2007, v. 59, n. 7, p. 947, doi. 10.1211/jpp.59.7.0006

By:

Michael D. Perloff;
Lisa L. von Moltke;
Jeanne M. Fahey;
David J. Greenblatt

Publication type:

Article

Ethanol inhibits in-vitro metabolism of nifedipine, triazolam and testosterone in human liver microsomes.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 8, p. 963

By:

Kiran C. Patki;
David J. Greenblatt;
Lisa L. von Moltke

Publication type:

Article

Inhibition of human cytochromes P450 by components of Ginkgo biloba.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 8, p. 1039

By:

Lisa L. von Moltke;
James L. Weemhoff;
Erdal Bedir;
Ikhlas A. Khan;
Jerold S. Harmatz;
Peter Goldman;
David J. Greenblatt

Publication type:

Article

Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 6, p. 819

By:

Jill S. Warrington;
Michael H. Court;
David J. Greenblatt;
Lisa L. von Moltke

Publication type:

Article

Phenacetin and chlorzoxazone biotransformation in aging male Fischer 344 rats.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 6, p. 819

By:

Jill S. Warrington;
Michael H. Court;
David J. Greenblatt;
Lisa L. von Moltke

Publication type:

Article

Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin.

Published in:

Journal of Pharmacy & Pharmacology, 2003, v. 55, n. 9, p. 1229

By:

Leah M. Hesse;
Daesety Vishnuvardhan;
Lisa L. Von Moltke;
David J. Greenblatt;
Yumiko Sakai;
Albert P. Li

Publication type:

Article

Apparent mechanism-based inhibition of human CYP3A in-vitro by lopinavir.

Published in:

Journal of Pharmacy & Pharmacology, 2003, v. 55, n. 3, p. 381, doi. 10.1211/002235702739

By:

Weemhoff, James L.;
Moltke, Lisa L.;
Richert, Clemens;
Hesse, Leah M.;
Harmatz, Jerold S.;
Greenblatt, David J.

Publication type:

Article

Effect of 7-day exposure to midazolam on electroencephalogram pharmacodynamics in rats: a model to study multiple pharmacokinetic-pharmacodynamic relationships in individual animals.

Published in:

Journal of Pharmacy & Pharmacology, 2002, v. 54, n. 1, p. 77, doi. 10.1211/0022357021771959

By:

Laurijssens, Bart E.;
Greenblatt, David J.

Publication type:

Article

Lou Lasagna, 1923-2003.

Published in:

2004

By:

Greenblatt, David J.

Publication type:

Obituary

Interdose Elevation in Plasma Cortisol During Chronic Treatment with Alprazolam but not Lorazepam in the Elderly.

Published in:

Neuropsychopharmacology, 2004, v. 29, n. 3, p. 605, doi. 10.1038/sj.npp.1300365

By:

Pomara, Nunzio;
Willoughby, Lisa M.;
Ritchie, James C.;
Sidtis, John J.;
Greenblatt, David J.;
Nemeroff, Charles B.

Publication type:

Article

Chlorpromazine and Hyperpyrexia.

Published in:

Clinical Pediatrics, 1973, v. 12, n. 8, p. 504

By:

Greenblatt, David J.;
Greenblatt, Gertrude Rogers

Publication type:

Article

Impairment of Hepatic Drug Oxidation by Propoxyphene.

Published in:

1982

By:

Abernethy, Darrell R.;
Greenblatt, David J.;
Steel, Knight;
Shader, Richard I.

Publication type:

Case Study

Treatment of diazepam withdrawal syndrome with propranolol.

Published in:

1981

By:

Abernethy, Darrell R.;
Greenblatt, David J.;
Shader, Richard I.;
Abernethy, D R;
Greenblatt, D J;
Shader, R I

Publication type:

journal article

Vancomycin therapy in patients with impaired renal function: a nomogram for dosage.

Published in:

1981

By:

Moellering Jr., Robert C.;
Krogstad, Donald J.;
Greenblatt, David J.;
Moellering, R C Jr;
Krogstad, D J;
Greenblatt, D J

Publication type:

journal article

Acetaminophen.

Published in:

Annals of Internal Medicine, 1977, v. 87, n. 2, p. 202, doi. 10.7326/0003-4819-87-2-202

By:

Ameer, Barbara;
Greenblatt, David J.

Publication type:

Article

Flurazepam Hydrochloride, a Benzodiazepine Hypnotic.

Published in:

Annals of Internal Medicine, 1975, v. 83, n. 2, p. 237, doi. 10.7326/0003-4819-83-2-237

By:

Greenblatt, David J.;
Shader, Richard I.;
Koch-Weser, Jan

Publication type:

Article

Reduction of Digoxin Toxicity Associated with Measurement of Serum Levels.

Published in:

Annals of Internal Medicine, 1974, v. 80, n. 4, p. 516, doi. 10.7326/0003-4819-80-4-516

By:

Duhme, David W.;
Greenblatt, David J.;
Koch-Weser, Jan

Publication type:

Article

The clinical choice of sedative-hypnotics.

Published in:

1972

By:

Greenblatt, David J.;
Greenblatt, D J;
Shader, R I

Publication type:

journal article

The Acute and Chronic Performance Effects of Alprazolam and Lorazepam in the Elderly: Relationship to Duration of Treatment and Self-Rated Sedation

Published in:

Psychopharmacology Bulletin, 1998, v. 34, n. 2, p. 139

By:

Pomara, Nunzio;
Tun, Hla;
DaSilva, Dan;
Hernando, Raymundo;
Deptula, Dennis;
Greenblatt, David J.

Publication type:

Article

Sertraline Does Not Inhibit Cytochrome P450 3A-Mediated Drug Metabolism In Vivo

Published in:

Psychopharmacology Bulletin, 1997, v. 33, n. 4, p. 659

By:

Preskorn, Sheldon H.;
Alderman, Jeff;
Greenblatt, David J.;
Horst, W. Dale

Publication type:

Article

P3-204: Is the APOE-e4 allele associated with increased vulnerability of primacy words to retrograde interference in healthy elderly?

Published in:

2006

By:

Pomara, Nunzio;
Roth, Amy E.;
Willoughby, Lisa M.;
Wesnes, Keith A.;
Greenblatt, David J.;
Sidtis, John J.

Publication type:

Abstract

P3-204: Is the APOE-e4 allele associated with increased vulnerability of primacy words to retrograde interference in healthy elderly?

Published in:

2006

By:

Pomara, Nunzio;
Roth, Amy E.;
Willoughby, Lisa M.;
Wesnes, Keith A.;
Greenblatt, David J.;
Sidtis, John J.

Publication type:

Abstract

Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects.

Published in:

2012

By:

Smithline, Howard A;
Donnino, Michael;
Greenblatt, David J

Publication type:

Journal Article

Inhibition of Human Cytochrome P450 Isoforms by Nonnucleoside Reverse Transcriptase Inhibitors.

Published in:

Journal of Clinical Pharmacology, 2001, v. 41, n. 1, p. 85, doi. 10.1177/009127000104100i110

By:

von Moltke, Lisa L.;
Greenblatt, David J.;
Granda, Brian W.;
Giancarlo, Gina M.;
Duan, Su Xiang;
Daily, Johanna P.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Article

Academic Perspectives on the MTD: Pharmacodynamic End Points: Maximizing the Value of MTD Studies.

Published in:

Journal of Clinical Pharmacology, 2000, v. 40, n. 11, p. 1188, doi. 10.1177/009127000004001102

By:

Greenblatt, David J.

Publication type:

Article

The Influence of the Menstrual Cycle on Triazolam and Indocyanine Green Pharmacokinetics.

Published in:

Journal of Clinical Pharmacology, 2000, v. 40, n. 7, p. 739, doi. 10.1177/00912700022009495

By:

Kamimori, Gary H.;
Sirisuth, Nattee;
Greenblatt, David J.;
Eddington, Natalie D.

Publication type:

Article

Unusually Low Clearance of Two CYP3A Substrates, Alprazolam and Trazodone, in a Volunteer Subject with Wild-Type CYP3A4 Promoter Region.

Published in:

Journal of Clinical Pharmacology, 2000, v. 40, n. 2, p. 200, doi. 10.1177/009127000004000212

By:

von Moltke, Lisa L.;
Tran, Thanh Huu;
Cotreau, Monette M.;
Greenblatt, David J.

Publication type:

Article

Decreased EEG Sensitivity to Alprazolam in Subjects with a Parental History of Alcoholism.

Published in:

Journal of Clinical Pharmacology, 2000, v. 40, n. 1, p. 84, doi. 10.1177/009127000004000111

By:

Sarid-Segal, Ofra;
Knapp, Clifford M.;
Ciraulo, Ann Marie;
Greenblatt, David J.;
Shader, Richard I.;
Ciraulo, Domenic A.

Publication type:

Article

Population Pharmacokinetics of Methylphenidate in Children with Attention-Deficit Hyperactivity Disorder.

Published in:

Journal of Clinical Pharmacology, 1999, v. 39, n. 8, p. 775, doi. 10.1177/009127009903900802

By:

Shader, Richard I.;
Harmatz, Jerold S.;
Oesterheld, Jessica R.;
Parmelee, Dean X.;
Sallee, Floyd R.;
Greenblatt, David J.

Publication type:

Article

Nortriptyline E-10-Hydroxylation in Vitro Is Mediated by Human CYP2D6 (High Affinity) and CYP3A4 (Low Affinity): Implications for Interactions with Enzyme-Inducing Drugs.

Published in:

Journal of Clinical Pharmacology, 1999, v. 39, n. 6, p. 567, doi. 10.1177/009127009903900603

By:

Venkatakrishnan, Karthik;
von Moltke, Lisa L.;
Greenblatt, David J.

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Diphenhydramine 25 mg in Young and Elderly Volunteers.

Published in:

1998

By:

Scavone, Joseph M.;
Greenblatt, David J.;
Harmatz, Jerold S.;
Engelhardt, Nina;
Shader, Richard I.

Publication type:

Other

The Maturation of Clinical Pharmacology: Recognizing the Contributions of Dr. Louis Lasagna.

Published in:

1998

By:

Greenblatt, David J.

Publication type:

Other

Five Distinct Human Cytochromes Mediate Amitriptyline N-Demethylation In Vitro: Dominance of CYP 2C19 and 3A4.

Published in:

1998

By:

Venkatakrishnan, Karthik;
Greenblatt, David J.;
Moltke, Lisa L.;
Schmider, Jürgen;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Protease Inhibitors as Inhibitors of Human Cytochromes P450: High Risk Associated with Ritonavir.

Published in:

1998

By:

Moltke, Lisa L.;
Greenblatt, David J.;
Grassi, Jeffrey M.;
Granda, Brian W.;
Duan, Su Xiang;
Fogelman, Steven M.;
Daily, Johanna P.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Single-Dose Pharmacokinetics and Pharmacodynamics of Alprazolam in Elderly and Young Subjects.

Published in:

1998

By:

Kaplan, Gary B.;
Greenblatt, David J.;
Ehrenberg, Bruce L.;
Goddard, Jill E.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Defining the Maximum Tolerated Dose: Investigator, Academic, Industry and Regulatory Perspectives.

Published in:

1997

By:

Cutler, Neal R.;
Sramek, John J.;
Greenblatt, David J.;
Chaikin, Philip;
Ford, Neville;
Lesko, Lawrence J.;
Davis, Brian;
Williams, Roger L.

Publication type:

Other

Dose-Dependent Pharmacokinetics and Psychomotor Effects of Caffeine in Humans.

Published in:

1997

By:

Kaplan, Gary B.;
Greenblatt, David J.;
Ehrenberg, Bruce L.;
Goddard, Jill E.;
Cotreau, Monette M.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Influence of Oral Contraceptive Use and Cigarette Smoking, Alone and Together, on Antipyrine Pharmacokinetics.

Published in:

1997

By:

Scavone, Joseph M.;
Greenblatt, David J.;
Abernethy, Darrell R.;
Luna, Becki G.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Biotransformation of Mestranol to Ethinyl Estradiol In Vitro: The Role of Cytochrome P-450 2C9 and Metabolic Inhibitors.

Published in:

1997

By:

Schmider, Jürgen;
Greenblatt, David J.;
Moltke, Lisa L.;
Karsov, Dmitri;
Vena, Richard;
Friedman, Hylar L.;
Shader, Richard I.

Publication type:

Other