Works matching AU Das, Umashankar

Results: 30

Does Ortho-Substitution Enhance Cytotoxic Potencies in a Series of 3,5-Bis(benzylidene)-4-piperidones?

Published in:

Medicines, 2024, v. 11, n. 8, p. 19, doi. 10.3390/medicines11080019

By:

Karki, Subhas S.;
Das, Umashankar;
Balzarini, Jan;
De Clercq, Erik;
Sakagami, Hiroshi;
Uesawa, Yoshihiro;
Roayapalley, Praveen K.;
Dimmock, Jonathan R.

Publication type:

Article

Dimeric 3,5-Bis(benzylidene)-4-piperidones: Tumor-Selective Cytotoxicity and Structure-Activity Relationships.

Published in:

Medicines, 2024, v. 11, n. 1, p. 3, doi. 10.3390/medicines11010003

By:

Das, Swagatika;
Roayapalley, Praveen K.;
Sakagami, Hiroshi;
Umemura, Naoki;
Gorecki, Dennis K. J.;
Hossain, Mohammad;
Kawase, Masami;
Das, Umashankar;
Dimmock, Jonathan R.

Publication type:

Article

Anticonvulsant Properties of 1-Diethylamino-3-phenylprop-2-en-1-one.

Published in:

Medicines, 2023, v. 10, n. 9, p. 54, doi. 10.3390/medicines10090054

By:

Das, Swagatika;
Roayapalley, Praveen K.;
Vashishtha, Sarvesh C.;
Das, Umashankar;
Dimmock, Jonathan R.

Publication type:

Article

Dichloroacetyl Amides of 3,5-Bis(benzylidene)-4-piperidones Displaying Greater Toxicity to Neoplasms than to Non-Malignant Cells.

Published in:

Medicines, 2022, v. 9, n. 6, p. 1, doi. 10.3390/medicines9060035

By:

Hossain, Mohammad;
Roayapalley, Praveen K.;
Hiroshi Sakagami;
Keitaro Satoh;
Kenjiro Bandow;
Das, Umashankar;
Dimmock, Jonathan R.

Publication type:

Article

Niacin esters of chalcones with tumor-selective properties.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1451, doi. 10.3109/14756366.2016.1144595

By:

Panda, Atulya K.;
Das, Umashankar;
Roayapalley, Praveen K.;
Sakagami, Hiroshi;
Kawase, Masami;
Balzarini, Jan;
De Clercq, Erik;
Dimmock, Jonathan R.

Publication type:

Article

3-Benzylidene-4-chromanones: a novel cluster of anti-tubercular agents.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 2, p. 259, doi. 10.3109/14756366.2014.913036

By:

Das, Umashankar;
Lorand, Tamas;
Dimmock, Stephen G.;
Perjesi, Pal;
Dimmock, Jonathan R.

Publication type:

Article

1-(3-Aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones: A novel group of tumour-selective cytotoxins.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 5, p. 974, doi. 10.3109/14756366.2012.700927

By:

Bilginer, Sinan;
Gul, Halise Inci;
Mete, Ebru;
Das, Umashankar;
Sakagami, Hiroshi;
Umemura, Naoki;
Dimmock, Jonathan Richard

Publication type:

Article

Investigations on Binding Pattern of Kinase Inhibitors with PPARγ: Molecular Docking, Molecular Dynamic Simulations, and Free Energy Calculation Studies.

Published in:

PPAR Research, 2017, p. 1, doi. 10.1155/2017/6397836

By:

Mazumder, Mohit;
Ponnan, Prija;
Das, Umashankar;
Gourinath, Samudrala;
Khan, Haseeb Ahmad;
Yang, Jian;
Sakharkar, Meena Kishore

Publication type:

Article

The Gender of Cell Lines Matters When Screening for Novel Anti-Cancer Drugs.

Published in:

AAPS Journal, 2014, v. 16, n. 4, p. 872, doi. 10.1208/s12248-014-9617-4

By:

Nunes, Larissa;
Robles-Escajeda, Elisa;
Santiago-Vazquez, Yahaira;
Ortega, Nora;
Lema, Carolina;
Muro, Almendra;
Almodovar, Gladys;
Das, Umashankar;
Das, Swagatika;
Dimmock, Johnatan;
Aguilera, Renato;
Varela-Ramirez, Armando

Publication type:

Article

Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones.

Published in:

Cellular Oncology (2211-3428), 2018, v. 41, n. 6, p. 623, doi. 10.1007/s13402-018-0397-1

By:

Contreras, Lisett;
Calderon, Ruben I.;
Varela-Ramirez, Armando;
Zhang, Hong-Yu;
Quan, Yuan;
Das, Umashankar;
Dimmock, Jonathan R.;
Skouta, Rachid;
Aguilera, Renato J.

Publication type:

Article

A novel curcumin-like dienone induces apoptosis in triple-negative breast cancer cells.

Published in:

Cellular Oncology (2211-3428), 2016, v. 39, n. 3, p. 265, doi. 10.1007/s13402-016-0272-x

By:

Robles-Escajeda, Elisa;
Das, Umashankar;
Ortega, Nora;
Parra, Karla;
Francia, Giulio;
Dimmock, Jonathan;
Varela-Ramirez, Armando;
Aguilera, Renato

Publication type:

Article

Roles of Histone Deacetylases and Inhibitors in Anticancer Therapy.

Published in:

Cancers, 2020, v. 12, n. 6, p. 1664, doi. 10.3390/cancers12061664

By:

Verza, Flávia Alves;
Das, Umashankar;
Fachin, Ana Lúcia;
Dimmock, Jonathan R.;
Marins, Mozart

Publication type:

Article

Comparative QSAR Analysis of 3,5-bis (Arylidene)-4-Piperidone Derivatives: the Development of Predictive Cytotoxicity Models.

Published in:

Iranian Journal of Pharmaceutical Research, 2016, v. 15, n. 2, p. 425

By:

Edraki, Najmeh;
Das, Umashankar;
Hemateenejad, Bahram;
Dimmock, Jonathan R.;
Miri, Ramin

Publication type:

Article

Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines.

Published in:

Investigational New Drugs, 2022, v. 40, n. 5, p. 905, doi. 10.1007/s10637-022-01266-y

By:

Swain, Risa Mia;
Contreras, Lisett;
Varela-Ramirez, Armando;
Hossain, Mohammad;
Das, Umashankar;
Valenzuela, Carlos A.;
Penichet, Manuel L.;
Dimmock, Jonathan R.;
Aguilera, Renato J

Publication type:

Article

Bis[3,5-bis(benzylidene)-4-oxo-1-piperidinyl]amides: A Novel Class of Potent Cytotoxins.

Published in:

ChemMedChem, 2011, v. 6, n. 10, p. 1892, doi. 10.1002/cmdc.201100199

By:

Das, Swagatika;
Das, Umashankar;
Varela-Ramírez, Armando;
Lema, Carolina;
Aguilera, Renato J.;
Balzarini, Jan;
De Clercq, Erik;
Dimmock, Stephen G.;
Gorecki, Dennis K. J.;
Dimmock, Jonathan R.

Publication type:

Article

3,5-Bis(benzylidene)-4-oxo-1-phosphonopiperidines and Related Diethyl Esters: Potent Cytotoxins with Multi-Drug-Resistance Reverting Properties.

Published in:

ChemMedChem, 2009, v. 4, n. 11, p. 1831, doi. 10.1002/cmdc.200900288

By:

Das, Swagatika;
Das, Umashankar;
Selvakumar, Ponniah;
Sharma, Rajendra K.;
Balzarini, Jan;
De Clercq, Erik;
Molnár, Joseph;
Serly, Julianna;
Baráth, Zoltán;
Schatte, Gabriele;
Bandy, Brian;
Gorecki, Dennis K. J.;
Dimmock, Jonathan R.

Publication type:

Article

Biological Evaluation and Structure-Activity Relationships of Bis-(3-aryl-3-oxo-propyl)-methylamine Hydrochlorides and 4-Aryl-3- arylcarbonyl-1-methyl-4-piperidinol Hy-drochlorides as Potential Cytotoxic Agents and their Alkylating Ability towards...

Published in:

Drug Research / Arzneimittel-Forschung (Editio Cantor Verlag fur Medizin und Naturwissenschaften), 2005, v. 55, n. 6, p. 332

By:

Gul, Mustafa;
Gul, Halise Inci;
Das, Umashankar;
Hanninena, Osmo

Publication type:

Article

A novel class of piperidones exhibit potent, selective and pro-apoptotic anti-leukemia properties.

Published in:

Oncology Letters, 2016, v. 11, n. 6, p. 3842, doi. 10.3892/ol.2016.4480

By:

NUNES, LARISSA M.;
HOSSAIN, MOHAMMAD;
VARELA-RAMIREZ, ARMANDO;
DAS, UMASHANKAR;
AYALA-MARIN, YOSHIRA M.;
DIMMOCK, JONATHAN R.;
AGUILERA, RENATO J.

Publication type:

Article

Cytotoxic derivatives of dichloroacetic acid and some metal complexes.

Published in:

Archiv der Pharmazie, 2022, v. 355, n. 11, p. 1, doi. 10.1002/ardp.202200236

By:

Hossain, Mohammad;
Roth, Shayne;
Dimmock, Jonathan R.;
Das, Umashankar

Publication type:

Article

1-Arylmethyl-2,3-dioxo-2,3-dihydroindole thiosemicarbazones as leads for developing cytotoxins and anticonvulsants.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 2, p. 537, doi. 10.1080/14756360802234885

By:

Karki, Subhas S.;
Bahaduria, Vivek Singh;
Rana, Vivek;
Kumar, Sujeet;
Subbaro, Prasanna G.;
Das, Umashankar;
Balzarini, Jan;
De Clercq, Erik;
Dimmock, Jonathan R.

Publication type:

Article

N-Acyl-3,5-bis(arylidene)-4-piperidones and related compounds which stimulate fyn kinase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 4, p. 451, doi. 10.1080/14756360701192515

By:

Das, Umashankar;
Selvakumar, Ponniah;
Sharma, Rajendra K.;
Haas, Thomas A.;
Dimmock, Jonathan R.

Publication type:

Article

Molecular modifications of 2-arylidene-1-indanones leading to increased cytotoxic potencies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 1, p. 37, doi. 10.1080/14756360600958057

By:

Pati, Hari N.;
Das, Umashankar;
Clercq, Erik De;
Balzarini, Jan;
Dimmock, Jonathan R.

Publication type:

Article

Clinical Symptoms and Types of Samples Are Critical Factors for the Molecular Diagnosis of Symptomatic COVID-19 Patients: A Systematic Literature Review.

Published in:

International Journal of Microbiology, 2021, p. 1, doi. 10.1155/2021/5528786

By:

Zandi, Milad;
Farahani, Abbas;
Zakeri, Armin;
Akhavan Rezayat, Sara;
Mohammadi, Ramin;
Das, Umashankar;
Dimmock, Jonathan R.;
Afzali, Shervin;
Nakhaei, Mohammadvala Ashtar;
Doroudi, Alireza;
Erfani, Yousef;
Soltani, Saber

Publication type:

Article

Retracted: Hydrogen production using catalytic and noncatalytic supercritical water gasification of bagasse.

Published in:

International Journal of Energy Research, 2014, v. 38, n. 10, p. 1366, doi. 10.1002/er.3134

By:

Barati, Mohammad;
Babatabar, Mokhtar;
Tavasoli, Ahmad;
Dalai, Ajay K.;
Das, Umashankar

Publication type:

Article

2-(3-ARYLACRYLOYL)-3-METHYLQUINOXALINE 1,4-DIOXIDES AS POTENTIAL HYPOXIC SELECTIVE CYTOTOXINS.

Published in:

Heterocyclic Communications, 2008, v. 14, n. 5, p. 385

By:

Dittenhafer, Kristin;
Das, Umashankar;
Younglove, Brent L.;
Mackay, Hilary;
Brown, Toni;
Dimmock, Jonathan R.;
Lee, Moses;
Pati, Hari

Publication type:

Article

The Design and Cytotoxic Evaluation of Some 1-Aryl-3-isopropylamino-1-propanone Hydrochlorides towards Human Huh-7 Hepatoma Cells.

Published in:

Archiv der Pharmazie, 2011, v. 344, n. 5, p. 333, doi. 10.1002/ardp.201000194

By:

Mete, Ebru;
Gul, H. Inci;
Cetin-Atalay, Rengul;
Das, Umashankar;
Sahin, Ertan;
Gul, Mustafa;
Kazaz, Cavit;
Dimmock, Jonathan R.

Publication type:

Article

1,3-Diaryl-2-propenones and 2-Benzylidene-1,3-indandiones: A Quest for Compounds Displaying Greater Toxicity to Neoplasms than Normal Cells.

Published in:

Archiv der Pharmazie, 2010, v. 343, n. 9, p. 535, doi. 10.1002/ardp.200900308

By:

Pati, Hari N.;
Das, Umashankar;
Sakagami, Hiroshi;
Kawase, Masame;
Chu, Qing;
Wang, Qintao;
Stables, James P.;
Dimmock, Jonathan R.

Publication type:

Article

Novel Unsymmetric 3,5-Bis(benzylidene)-4-piperidones That Display Tumor-Selective Toxicity.

Published in:

Molecules, 2022, v. 27, n. 19, p. 6718, doi. 10.3390/molecules27196718

By:

Chhikara, Aruna;
Roayapalley, Praveen K.;
Sakagami, Hiroshi;
Amano, Shigeru;
Satoh, Keitaro;
Uesawa, Yoshihiro;
Das, Umashankar;
Das, Swagatika;
Borrego, Edgar A.;
Guerena, Cristina D.;
Hernandez, Clare R.;
Aguilera, Renato J.;
Dimmock, Jonathan R.

Publication type:

Article

Design, Synthesis and Tumour-Selective Toxicity of Novel 1-[3-{3,5-Bis(benzylidene)-4-oxo-1-piperidino}-3-oxopropyl]-4-piperidone Oximes and Related Quaternary Ammonium Salts.

Published in:

Molecules, 2021, v. 26, n. 23, p. 7132, doi. 10.3390/molecules26237132

By:

Roayapalley, Praveen K.;
Dimmock, Jonathan R.;
Contreras, Lisett;
Balderrama, Karol S.;
Aguilera, Renato J.;
Sakagami, Hiroshi;
Amano, Shigeru;
Sharma, Rajendra K.;
Das, Umashankar

Publication type:

Article

Characterization of the host-guest complex of a curcumin analog with ß-cyclodextrin and ß-cyclodextrin-gemini surfactant and evaluation of its anticancer activity.

Published in:

International Journal of Nanomedicine, 2015, v. 10, p. 503, doi. 10.2147/IJN.S70828

By:

Poorghorban, Masoomeh;
Das, Umashankar;
Alaidi, Osama;
Chitanda, Jackson M.;
Michel, Deborah;
Dimmock, Jonathan;
Verrall, Ronald;
Grochulski, Pawel;
Badea, Ildiko

Publication type:

Article