Works matching AU Darwin, K. Heran

Results: 28

Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium tuberculosis Pup Proteasome System**.

Published in:

ChemBioChem, 2021, v. 22, n. 21, p. 3082, doi. 10.1002/cbic.202100333

By:

Janssen, Guido V.;
Zhang, Susan;
Merkx, Remco;
Schiesswohl, Christa;
Chatterjee, Champak;
Darwin, K. Heran;
Geurink, Paul P.;
van der Heden van Noort, Gerbrand J.;
Ovaa, Huib

Publication type:

Article

Copper homeostasis in Mycobacterium tuberculosis.

Published in:

Metallomics, 2015, v. 7, n. 6, p. 929, doi. 10.1039/c4mt00305e

By:

Shi, Xiaoshan;
Darwin, K. Heran

Publication type:

Article

Type III secretion chaperone-dependent regulation: activation of virulence genes by SicA and InvF in Salmonella typhimurium.

Published in:

EMBO Journal, 2001, v. 20, n. 8, p. 1850, doi. 10.1093/emboj/20.8.1850

By:

Darwin, K. Heran;
Miller, Virginia L.

Publication type:

Article

Prokaryotic ubiquitin-like protein (Pup), proteasomes and pathogenesis.

Published in:

Nature Reviews Microbiology, 2009, v. 7, n. 7, p. 485, doi. 10.1038/nrmicro2148

By:

Darwin, K. Heran

Publication type:

Article

Self-compartmentalized bacterial proteases and pathogenesis.

Published in:

Molecular Microbiology, 2006, v. 60, n. 3, p. 553, doi. 10.1111/j.1365-2958.2006.05128.x

By:

Butler, Susan M.;
Festa, Richard A.;
Pearce, Michael J.;
Darwin, K. Heran

Publication type:

Article

A glutamate-alanine-leucine (EAL) domain protein ofSalmonellacontrols bacterial survival in mice, antioxidant defence and killing of macrophages: role of cyclic diGMP.

Published in:

Molecular Microbiology, 2005, v. 56, n. 5, p. 1234, doi. 10.1111/j.1365-2958.2005.04632.x

By:

Hisert, Katherine B.;
MacCoss, Michael;
Shiloh, Michael U.;
Darwin, K. Heran;
Singh, Shaneen;
Jones, Roger A.;
Ehrt, Sabine;
Zhang, Zhaoying;
Gaffney, Barbara L.;
Gandotra, Sheetal;
Holden, David W.;
Murray, Diana;
Nathan, Carl

Publication type:

Article

Characterization of aMycobacterium tuberculosisproteasomal ATPase homologue.

Published in:

Molecular Microbiology, 2005, v. 55, n. 2, p. 561, doi. 10.1111/j.1365-2958.2004.04403.x

By:

Darwin, K. Heran;
Lin, Gang;
Chen, Zhiqiang;
Li, Huilin;
Nathan, Carl F.

Publication type:

Article

The putative invasion protein chaperone SicA acts together with InvF to activate the expression of Salmonella typhimurium virulence genes.

Published in:

Molecular Microbiology, 2000, v. 35, n. 4, p. 949, doi. 10.1046/j.1365-2958.2000.01772.x

By:

Darwin, K. Heran;
Miller, Virginia L

Publication type:

Article

Role of the transcriptional regulator SP140 in resistance to bacterial infections via repression of type I interferons.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.67290

By:

Ji, Daisy X.;
Witt, Kristen C.;
Kotov, Dmitri I.;
Margolis, Shally R.;
Louie, Alexander;
Chevée, Victoria;
Chen, Katherine J.;
Gaidt, Moritz M.;
Dhaliwal, Harmandeep S.;
Lee, Angus Y.;
Nishimura, Stephen L.;
Zamboni, Dario S.;
Kramnik, Igor;
Portnoy, Daniel A.;
Darwin, K. Heran;
Vance, Russell E.

Publication type:

Article

Mycobacterium tuberculosis copper-regulated protein SocB is an intrinsically disordered protein that folds upon interaction with a synthetic phospholipid bilayer.

Published in:

Proteins, 2016, v. 84, n. 2, p. 193, doi. 10.1002/prot.24970

By:

Nowicka, Urszula;
Hoffman, Morgan;
Randles, Leah;
Shi, Xiaoshan;
Khavrutskii, Lyuba;
Stefanisko, Karen;
Tarasova, Nadya I.;
Darwin, K. Heran;
Walters, Kylie J.

Publication type:

Article

Synthesis and Evaluation of a Selective Fluorogenic Pup Derived Assay Reagent for Dop, a Potential Drug Target in Mycobacterium tuberculosis.

Published in:

ChemBioChem, 2012, v. 13, n. 14, p. 2056, doi. 10.1002/cbic.201200460

By:

Merkx, Remco;
Burns, Kristin E.;
Slobbe, Paul;
El Oualid, Farid;
El Atmioui, Dris;
Darwin, K. Heran;
Ovaa, Huib

Publication type:

Article

Mycobacterium tuberculosis proteasomal ATPase Mpa has a β-grasp domain that hinders docking with the proteasome core protease.

Published in:

Molecular Microbiology, 2017, v. 105, n. 2, p. 227, doi. 10.1111/mmi.13695

By:

Wu, Yujie;
Hu, Kuan;
Li, Defeng;
Bai, Lin;
Yang, Shaoqing;
Jastrab, Jordan B.;
Xiao, Shuhao;
Hu, Yonglin;
Zhang, Susan;
Darwin, K. Heran;
Wang, Tao;
Li, Huilin

Publication type:

Article

A novel copper-responsive regulon in Mycobacterium tuberculosis.

Published in:

Molecular Microbiology, 2011, v. 79, n. 1, p. 133, doi. 10.1111/j.1365-2958.2010.07431.x

By:

Festa, Richard A.;
Jones, Marcus B.;
Butler-Wu, Susan;
Sinsimer, Daniel;
Gerads, Russell;
Bishai, William R.;
Peterson, Scott N.;
Darwin, K. Heran

Publication type:

Article

Molecular analysis of the prokaryotic ubiquitin-like protein (Pup) conjugation pathway in Mycobacterium tuberculosis F. A. Cerda-Maira et al. Pup conjugation pathway.

Published in:

Molecular Microbiology, 2010, v. 77, n. 5, p. 1123, doi. 10.1111/j.1365-2958.2010.07276.x

By:

Cerda-Maira, Francisca A.;
Pearce, Michael J.;
Fuortes, Michele;
Bishai, William R.;
Hubbard, Stevan R.;
Darwin, K. Heran

Publication type:

Article

Pupylation versus ubiquitylation: tagging for proteasome-dependent degradation.

Published in:

Cellular Microbiology, 2010, v. 12, n. 4, p. 424, doi. 10.1111/j.1462-5822.2010.01447.x

By:

Burns, Kristin E.;
Darwin, K. Heran

Publication type:

Article

Identification of substrates of the Mycobacterium tuberculosis proteasome.

Published in:

EMBO Journal, 2006, v. 25, n. 22, p. 5423, doi. 10.1038/sj.emboj.7601405

By:

Pearce, Michael J.;
Arora, Pooja;
Festa, Richard A.;
Butler-Wu, Susan M.;
Gokhale, Rajesh S.;
Darwin, K. Heran

Publication type:

Article

Binding-induced folding of prokaryotic ubiquitin-like protein on the Mycobacterium proteasomal ATPase targets substrates for degradation.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 11, p. 1352, doi. 10.1038/nsmb.1918

By:

Tao Wang;
Darwin, K. Heran;
Huilin Li

Publication type:

Article

Prokayrotic Ubiquitin-Like Protein (Pup) Proteome of Mycobacterium tuberculosis.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008589

By:

Festa, Richard A.;
McAllister, Fiona;
Pearce, Michael J.;
Mintseris, Julian;
Burns, Kristin E.;
Gygi, Steven P.;
Darwin, K. Heran

Publication type:

Article

Goliath, meet David.

Published in:

EMBO Reports, 2024, v. 25, n. 10, p. 4091, doi. 10.1038/s44319-024-00257-9

By:

Darwin, K Heran

Publication type:

Article

The life-changing magic of doing a sabbatical.

Published in:

EMBO Reports, 2024, v. 25, n. 2, p. 459, doi. 10.1038/s44319-023-00042-0

By:

Darwin, K Heran

Publication type:

Article

Intervention.

Published in:

EMBO Reports, 2023, v. 24, n. 10, p. 1, doi. 10.15252/embr.202358022

By:

Darwin, K Heran

Publication type:

Article

Confusion.

Published in:

EMBO Reports, 2023, v. 24, n. 4, p. 1, doi. 10.15252/embr.202357041

By:

Darwin, K Heran;
Aldridge, Bree;
Seeliger, Jessica;
Shen, Aimee;
Stanley, Sarah

Publication type:

Article

Sci-Con.

Published in:

EMBO Reports, 2022, v. 23, n. 5, p. 1, doi. 10.15252/embr.202254958

By:

Darwin, K. Heran

Publication type:

Article

Work life balance?

Published in:

EMBO Reports, 2021, v. 22, n. 6, p. 1, doi. 10.15252/embr.202152874

By:

Darwin, K Heran

Publication type:

Article

After the year of the dumpster fire.

Published in:

EMBO Reports, 2021, v. 22, n. 3, p. 1, doi. 10.15252/embr.202152556

By:

Darwin, K Heran

Publication type:

Article

Dr. Manners.

Published in:

EMBO Reports, 2021, v. 22, n. 1, p. 1, doi. 10.15252/embr.202052066

By:

Darwin, K Heran

Publication type:

Article

Bandwagoning.

Published in:

EMBO Reports, 2020, v. 21, n. 11, p. 1, doi. 10.15252/embr.202051765

By:

Darwin, K. Heran

Publication type:

Article

Reconstitution of the Mycobacterium tuberculosis pupylation pathway in Escherichia coli.

Published in:

EMBO Reports, 2011, v. 12, n. 8, p. 863, doi. 10.1038/embor.2011.109

By:

Cerda-Maira, Francisca A;
McAllister, Fiona;
Bode, Nadine J;
Burns, Kristin E;
Gygi, Steven P;
Darwin, K Heran

Publication type:

Article