Works matching AU Darton, Thomas C.


Results: 46
    1

    Plumbing the Depths of Ethical Payment for Research Participation.

    Published in:
    American Journal of Bioethics, 2021, v. 21, n. 5, p. W8, doi. 10.1080/15265161.2021.1895364
    By:
    • Fernandez Lynch, Holly;
    • Darton, Thomas C.;
    • Levy, Jae;
    • McCormick, Frank;
    • Ogbogu, Ubaka;
    • Payne, Ruth O.;
    • Roth, Alvin E.;
    • Shah, Akilah Jefferson;
    • Smiley, Thomas;
    • Largent, Emily A.
    Publication type:
    Article
    2

    Promoting Ethical Payment in Human Infection Challenge Studies.

    Published in:
    American Journal of Bioethics, 2021, v. 21, n. 3, p. 11, doi. 10.1080/15265161.2020.1854368
    By:
    • Lynch, Holly Fernandez;
    • Darton, Thomas C.;
    • Levy, Jae;
    • McCormick, Frank;
    • Ogbogu, Ubaka;
    • Payne, Ruth O.;
    • Roth, Alvin E.;
    • Shah, Akilah Jefferson;
    • Smiley, Thomas;
    • Largent, Emily A.
    Publication type:
    Article
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    Infectious diseases burden and antibiotic prescribing patterns among primary care patients in Harare, Zimbabwe – a cross-sectional analysis.

    Published in:
    PLoS Global Public Health, 2025, v. 5, n. 4, p. 1, doi. 10.1371/journal.pgph.0004442
    By:
    • Olaru, Ioana D.;
    • Chingono, Rudo M. S.;
    • Mhino, Fadzaishe;
    • Gregson, Celia;
    • Bottomley, Christian;
    • Bandason, Tsitsi;
    • Mpandaguta, Chipo E.;
    • Madziva, Karlos;
    • Ferrand, Rashida A.;
    • Vere, Michael;
    • Chonzi, Prosper;
    • Munyati, Shungu;
    • Dixon, Justin;
    • Darton, Thomas C.;
    • Kranzer, Katharina
    Publication type:
    Article
    11

    Salmonella Typhi Bactericidal Antibodies Reduce Disease Severity but Do Not Protect against Typhoid Fever in a Controlled Human Infection Model.

    Published in:
    Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2017.01916
    By:
    • Juel, Helene B.;
    • Thomaides-Brears, Helena B.;
    • Darton, Thomas C.;
    • Jones, Claire;
    • Jones, Elizabeth;
    • Shrestha, Sonu;
    • Sie, Rebecca;
    • Eustace, Andrew;
    • Galal, Ushma;
    • Kurupati, Prathiba;
    • Van, Tan T.;
    • Thieu, Nga T. V.;
    • Baker, Stephen;
    • Blohmke, Christoph J.;
    • Pollard, Andrew J.
    Publication type:
    Article
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    Assessment and Translation of the Antibody-in-Lymphocyte Supernatant (ALS) Assay to Improve the Diagnosis of Enteric Fever in Two Controlled Human Infection Models and an Endemic Area of Nepal.

    Published in:
    Frontiers in Microbiology, 2017, p. 1, doi. 10.3389/fmicb.2017.02031
    By:
    • Darton, Thomas C.;
    • Jones, Claire;
    • Dongol, Sabina;
    • Voysey, Merryn;
    • Blohmke, Christoph J.;
    • Shrestha, Rajendra;
    • Karkey, Abhilasha;
    • Shakya, Mila;
    • Arjyal, Amit;
    • Waddington, Claire S.;
    • Gibani, Malick;
    • Carter, Michael J.;
    • Basnyat, Buddha;
    • Baker, Stephen;
    • Pollard, Andrew J.
    Publication type:
    Article
    19

    Identification of Novel Serodiagnostic Signatures of Typhoid Fever Using a Salmonella Proteome Array.

    Published in:
    Frontiers in Microbiology, 2017, p. 1, doi. 10.3389/fmicb.2017.01794
    By:
    • Darton, Thomas C.;
    • Baker, Stephen;
    • Randall, Arlo;
    • Dongol, Sabina;
    • Karkey, Abhilasha;
    • Voysey, Merryn;
    • Carter, Michael J.;
    • Jones, Claire;
    • Trappl, Krista;
    • Pablo, Jozelyn;
    • Hung, Chris;
    • Teng, Andy;
    • Shandling, Adam;
    • Tim Le;
    • Walker, Cassidy;
    • Molina, Douglas;
    • Andrews, Jason;
    • Arjyal, Amit;
    • Basnyat, Buddha;
    • Pollard, Andrew J.
    Publication type:
    Article
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    Assessment of an Antibody-in-Lymphocyte Supernatant Assay for the Etiological Diagnosis of Pneumococcal Pneumonia in Children.

    Published in:
    Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. 1, doi. 10.3389/fcimb.2019.00459
    By:
    • Carter, Michael J.;
    • Gurung, Pallavi;
    • Jones, Claire;
    • Rajkarnikar, Shristy;
    • Kandasamy, Rama;
    • Gurung, Meeru;
    • Thorson, Stephen;
    • Gautam, Madhav C.;
    • Prajapati, Krishna G.;
    • Khadka, Bibek;
    • Maharjan, Anju;
    • Knight, Julian C.;
    • Murdoch, David R.;
    • Darton, Thomas C.;
    • Voysey, Merryn;
    • Wahl, Brian;
    • O'Brien, Katherine L.;
    • Kelly, Sarah;
    • Ansari, Imran;
    • Shah, Ganesh
    Publication type:
    Article
    23

    Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases.

    Published in:
    EMBO Molecular Medicine, 2019, v. 11, n. 10, p. N.PAG, doi. 10.15252/emmm.201910431
    By:
    • Blohmke, Christoph J;
    • Muller, Julius;
    • Gibani, Malick M;
    • Dobinson, Hazel;
    • Shrestha, Sonu;
    • Perinparajah, Soumya;
    • Jin, Celina;
    • Hughes, Harri;
    • Blackwell, Luke;
    • Dongol, Sabina;
    • Karkey, Abhilasha;
    • Schreiber, Fernanda;
    • Pickard, Derek;
    • Basnyat, Buddha;
    • Dougan, Gordon;
    • Baker, Stephen;
    • Pollard, Andrew J;
    • Darton, Thomas C
    Publication type:
    Article
    24

    The Impact of Vaccination and Prior Exposure on Stool Shedding of Salmonella Typhi and Salmonella Paratyphi in 6 Controlled Human Infection Studies.

    Published in:
    Clinical Infectious Diseases, 2019, v. 68, n. 8, p. 1265, doi. 10.1093/cid/ciy670
    By:
    • Gibani, Malick M;
    • Voysey, Merryn;
    • Jin, Celina;
    • Jones, Claire;
    • Thomaides-Brears, Helena;
    • Jones, Elizabeth;
    • Baker, Philip;
    • Morgan, Marcus;
    • Simmons, Alison;
    • Gordon, Melita A;
    • Cerundolo, Vincenzo;
    • Pitzer, Virginia E;
    • Angus, Brian;
    • Levine, Myron M;
    • Darton, Thomas C;
    • Pollard, Andrew J
    Publication type:
    Article
    25

    Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model.

    Published in:
    Clinical Infectious Diseases, 2017, v. 64, n. 8, p. 1066, doi. 10.1093/cid/cix042
    By:
    • Dobinson, Hazel C.;
    • Gibani, Malick M.;
    • Jones, Claire;
    • Thomaides-Brears, Helena B.;
    • Voysey, Merryn;
    • Darton, Thomas C.;
    • Waddington, Claire S.;
    • Campbell, Danielle;
    • Milligan, Iain;
    • Liqing Zhou;
    • Shrestha, Sonu;
    • Kerridge, Simon A.;
    • Peters, Anna;
    • Stevens, Zoe;
    • Podda, Audino;
    • Martin, Laura B.;
    • D'Alessio, Flavia;
    • Thanh, Duy Pham;
    • Basnyat, Buddha;
    • Baker, Stephen
    Publication type:
    Article
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    Reply to Farmakiotis et al.

    Published in:
    2014
    By:
    • Waddington, Claire S.;
    • Darton, Thomas C.;
    • Angus, Brian;
    • Pollard, Andrew J.
    Publication type:
    Letter to the Editor
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    An Outpatient, Ambulant-Design, Controlled Human Infection Model Using Escalating Doses of Salmonella Typhi Challenge Delivered in Sodium Bicarbonate Solution.

    Published in:
    Clinical Infectious Diseases, 2014, v. 58, n. 9, p. 1230, doi. 10.1093/cid/ciu078
    By:
    • Waddington, Claire S.;
    • Darton, Thomas C.;
    • Jones, Claire;
    • Haworth, Kathryn;
    • Peters, Anna;
    • John, Tessa;
    • Thompson, Ben A. V.;
    • Kerridge, Simon A.;
    • Kingsley, Robert A.;
    • Zhou, Liqing;
    • Holt, Kathryn E.;
    • Yu, Ly-Mee;
    • Lockhart, Stephen;
    • Farrar, Jeremy J.;
    • Sztein, Marcelo B.;
    • Dougan, Gordon;
    • Angus, Brian;
    • Levine, Myron M.;
    • Pollard, Andrew J.
    Publication type:
    Article
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    Challenge of Humans with Wild-type Salmonella enterica Serovar Typhi Elicits Changes in the Activation and Homing Characteristics of Mucosal-Associated Invariant T Cells.

    Published in:
    Frontiers in Immunology, 2017, v. 8, p. 1, doi. 10.3389/fimmu.2017.00398
    By:
    • Salerno-Goncalves, Rosângela;
    • Luo, David;
    • Fresnay, Stephanie;
    • Magder, Laurence;
    • Darton, Thomas C.;
    • Jones, Claire;
    • Waddington, Claire S.;
    • Blohmke, Christoph J.;
    • Angus, Brian;
    • Levine, Myron M.;
    • Pollard, Andrew J.;
    • Sztein, Marcelo B.
    Publication type:
    Article
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    Direct inference and control of genetic population structure from RNA sequencing data.

    Published in:
    Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-05171-9
    By:
    • Fachrul, Muhamad;
    • Karkey, Abhilasha;
    • Shakya, Mila;
    • Judd, Louise M.;
    • Harshegyi, Taylor;
    • Sim, Kar Seng;
    • Tonks, Susan;
    • Dongol, Sabina;
    • Shrestha, Rajendra;
    • Salim, Agus;
    • Adhikari, Anup;
    • Banda, Happy Chimphako;
    • Blohmke, Christoph;
    • Darton, Thomas C.;
    • Farooq, Yama;
    • Ghimire, Maheshwar;
    • Hill, Jennifer;
    • Hoang, Nhu Tran;
    • Jere, Tikhala Makhaza;
    • Kamzati, Moses
    Publication type:
    Article
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    Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a.

    Published in:
    PLoS Neglected Tropical Diseases, 2016, v. 10, n. 8, p. 1, doi. 10.1371/journal.pntd.0004926
    By:
    • Darton, Thomas C.;
    • Jones, Claire;
    • Blohmke, Christoph J.;
    • Waddington, Claire S.;
    • Zhou, Liqing;
    • Peters, Anna;
    • Haworth, Kathryn;
    • Sie, Rebecca;
    • Green, Christopher A.;
    • Jeppesen, Catherine A.;
    • Moore, Maria;
    • Thompson, Ben A. V.;
    • John, Tessa;
    • Kingsley, Robert A.;
    • Yu, Ly-Mee;
    • Voysey, Merryn;
    • Hindle, Zoe;
    • Lockhart, Stephen;
    • Sztein, Marcelo B.;
    • Dougan, Gordon
    Publication type:
    Article
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