Works by Darszon, Alberto

Results: 63

Anion channels in the sea urchin sperm plasma membrane.

Published in:

Molecular Reproduction & Development, 1993, v. 36, n. 2, p. 174, doi. 10.1002/mrd.1080360208

By:

Morales, Ezequiel;
De La Torre, Lucia;
Moy, Gary W.;
Vacquier, Victor D.;
Darszon, Alberto

Publication type:

Article

Cdc42 localized in the CatSper signaling complex regulates cAMP-dependent pathways in mouse sperm.

Published in:

FASEB Journal, 2021, v. 35, n. 8, p. 1, doi. 10.1096/fj.202002773RR

By:

Luque, Guillermina M.;
Xinran Xu;
Romarowski, Ana;
Gervasi, María G.;
Orta, Gerardo;
De la Vega-Beltrán, José L.;
Stival, Cintia;
Gilio, Nicolás;
Dalotto-Moreno, Tomás;
Krapf, Dario;
Visconti, Pablo E.;
Krapf, Diego;
Darszon, Alberto;
Buffone, Mariano G.

Publication type:

Article

Membrane hyperpolarization abolishes calcium oscillations that prevent induced acrosomal exocytosis in human sperm.

Published in:

FASEB Journal, 2021, v. 35, n. 6, p. 1, doi. 10.1096/fj.202002333RR

By:

Balestrini, Paula A.;
Sanchez-Cardenas, Claudia;
Luque, Guillermina M.;
Graf, Carolina Baro;
Sierra, Jessica M.;
Hernández-Cruz, Arturo;
Visconti, Pablo E.;
Krapf, Dario;
Darszon, Alberto;
Buffone, Mariano G.

Publication type:

Article

Starvation induces an increase in intracellular calcium and potentiates the progesterone-induced mouse sperm acrosome reaction.

Published in:

FASEB Journal, 2021, v. 35, n. 4, p. 1, doi. 10.1096/fj.202100122R

By:

Sánchez-Cárdenas, Claudia;
Romarowski, Ana;
Orta, Gerardo;
De la Vega-Beltrán, José Luis;
Martín-Hidalgo, David;
Hernández-Cruz, Arturo;
Visconti, Pablo E.;
Darszon, Alberto

Publication type:

Article

Are TRP channels involved in sperm development and function?

Published in:

Cell & Tissue Research, 2012, v. 349, n. 3, p. 749, doi. 10.1007/s00441-012-1397-5

By:

Darszon, Alberto;
Sánchez-Cárdenas, Claudia;
Orta, Gerardo;
Sánchez-Tusie, Ana;
Beltrán, Carmen;
López-González, Ignacio;
Granados-González, Gisela;
Treviño, Claudia

Publication type:

Article

Epac activation induces an extracellular Ca2+‐independent Ca2+ wave that triggers acrosome reaction in human spermatozoa.

Published in:

Andrology, 2021, v. 9, n. 4, p. 1227, doi. 10.1111/andr.12989

By:

Mata‐Martínez, Esperanza;
Sánchez‐Tusie, Ana Alicia;
Darszon, Alberto;
Mayorga, Luis S.;
Treviño, Claudia L.;
De Blas, Gerardo A.

Publication type:

Article

Cytosolic and Acrosomal pH Regulation in Mammalian Sperm.

Published in:

Cells (2073-4409), 2024, v. 13, n. 10, p. 865, doi. 10.3390/cells13100865

By:

Chávez, Julio C.;
Carrasquel-Martínez, Gabriela;
Hernández-Garduño, Sandra;
Matamoros Volante, Arturo;
Treviño, Claudia L.;
Nishigaki, Takuya;
Darszon, Alberto

Publication type:

Article

Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24145-1

By:

Zhao, Ruiming;
Dai, Hui;
Arias, Rodolfo J.;
De Blas, Gerardo A.;
Orta, Gerardo;
Pavarotti, Martín A.;
Shen, Rong;
Perozo, Eduardo;
Mayorga, Luis S.;
Darszon, Alberto;
Goldstein, Steve A. N.

Publication type:

Article

Nonenzymatically oxidized arachidonic acid regulates T‐type Ca2+ currents in mouse spermatogenic cells.

Published in:

FEBS Letters, 2019, v. 593, n. 14, p. 1735, doi. 10.1002/1873-3468.13448

By:

Bondarenko, Olga;
Corzo, Gerardo;
Santana, Félix L.;
Río‐Portilla, Federico;
Darszon, Alberto;
López‐González, Ignacio

Publication type:

Article

Single cell imaging reveals that the motility regulator speract induces a flagellar alkalinization that precedes and is independent of Ca2+ influx in sea urchin spermatozoa.

Published in:

FEBS Letters, 2015, v. 589, n. 16, p. 2146, doi. 10.1016/j.febslet.2015.06.024

By:

González-Cota, Ana Laura;
Silva, Pedro Ângelo;
Carneiro, Jorge;
Darszon, Alberto

Publication type:

Article

Shal and Shaker Differential Contribution to the K+ Currents in the Drosophila Mushroom Body Neurons.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 9, p. 2348, doi. 10.1523/JNEUROSCI.4384-04.2005

By:

Gasque, Gabriel;
Labarca, Pedro;
Reynaud, Enrique;
Darszon, Alberto

Publication type:

Article

Heterologous calcium-dependent inactivation of Orai1 by neighboring TRPV1 channels modulates cell migration and wound healing.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0338-1

By:

Bastián-Eugenio, Carlos Ernesto;
Bohórquez-Hernández, Arlette;
Pacheco, Jonathan;
Sampieri, Alicia;
Asanov, Alexander;
Ocelotl-Oviedo, Jose Pablo;
Guerrero, Adán;
Darszon, Alberto;
Vaca, Luis

Publication type:

Article

3D+t Multifocal Imaging Dataset of Human Sperm.

Published in:

Scientific Data, 2025, v. 12, n. 1, p. 1, doi. 10.1038/s41597-025-05177-4

By:

Montoya, Fernando;
Bribiesca-Sánchez, Andrés;
Hernández-Herrera, Paul;
Díaz-Guerrero, Dan Sidney;
Gonzalez-Cota, Ana Laura;
Bloomfield-Gadelha, Hermes;
Darszon, Alberto;
Corkidi, Gabriel

Publication type:

Article

Differential role of bovine serum albumin and HCO3− in the regulation of GSK3 alpha during mouse sperm capacitation.

Published in:

Molecular Human Reproduction, 2024, v. 30, n. 3, p. 1, doi. 10.1093/molehr/gaae007

By:

Mohanty, Gayatri;
Sanchez-Cardenas, Claudia;
Paudel, Bidur;
Tourzani, Darya A;
Salicioni, Ana M;
Santi, Celia M;
Gervasi, María G;
Pilsner, J Richard;
Darszon, Alberto;
Visconti, Pablo E

Publication type:

Article

Acrosomal alkalinization occurs during human sperm capacitation.

Published in:

Molecular Human Reproduction, 2022, v. 28, n. 3, p. 1, doi. 10.1093/molehr/gaac005

By:

Martínez, Gabriela Carrasquel;
Aldana, Andrés;
Carneiro, Jorge;
Treviño, Claudia Lydia;
Darszon, Alberto

Publication type:

Article

Strategies for locating the female gamete: the importance of measuring sperm trajectories in three spatial dimensions.

Published in:

Molecular Human Reproduction, 2011, v. 17, n. 8, p. 511, doi. 10.1093/molehr/gar042

By:

Guerrero, Adán;
Carneiro, Jorge;
Pimentel, Arturo;
Wood, Christopher D.;
Corkidi, Gabriel;
Darszon, Alberto

Publication type:

Article

Speract induces calcium oscillations in the sperm tail.

Published in:

Journal of Cell Biology, 2003, v. 161, n. 1, p. 89, doi. 10.1083/jcb.200212053

By:

Wood, Chris D.;
Darszon, Alberto;
Whitaker, Michael

Publication type:

Article

Intracellular sodium changes during the speract response and the acrosome reaction in sea urchin sperm.

Published in:

Journal of Physiology, 2003, v. 546, n. 1, p. 89, doi. 10.1113/jphysiol.2002.030510

By:

Rodríguez, Esmeralda;
Darszon, Alberto

Publication type:

Article

Detection and functional characterization of ryanodine receptors from sea urchin eggs.

Published in:

Journal of Physiology, 1998, v. 510, n. 1, p. 155, doi. 10.1111/j.1469-7793.1998.155bz.x

By:

Lokuta, Andrew J.;
Darszon, Alberto;
Beltrán, Carmen;
Valdivia, Hector H.

Publication type:

Article

Extending resolution within a single imaging frame.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34693-9

By:

Torres-García, Esley;
Pinto-Cámara, Raúl;
Linares, Alejandro;
Martínez, Damián;
Abonza, Víctor;
Brito-Alarcón, Eduardo;
Calcines-Cruz, Carlos;
Valdés-Galindo, Gustavo;
Torres, David;
Jabloñski, Martina;
Torres-Martínez, Héctor H.;
Martínez, José L.;
Hernández, Haydee O.;
Ocelotl-Oviedo, José P.;
Garcés, Yasel;
Barchi, Marco;
D'Antuono, Rocco;
Bošković, Ana;
Dubrovsky, Joseph G.;
Darszon, Alberto

Publication type:

Article

Inner mitochondrial membranes bound to concanavalin A-sepharose display succinate dehydrogenase, ATPase, and cytochrome oxidase activity.

Published in:

Biotechnology & Bioengineering, 1992, v. 39, n. 11, p. 1080, doi. 10.1002/bit.260391103

By:

Strasser, Reto J.;
Millán, Lourdes;
Darszon, Alberto

Publication type:

Article

Reorganization of the flagellum scaffolding induces a sperm standstill during fertilization.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.93792

By:

Jabloñski, Martina;
Luque, Guillermina M.;
Elias, Matias Gomez;
Cardenas, Claudia Sanchez;
Xinran Xu;
de La Vega Beltran, Jose L.;
Corkidi, Gabriel;
Linares, Alejandro;
Abonza, Victor;
Arenas-Hernandez, Aquetzalli;
Ramos-Godinez, María D. P.;
López-Saavedra, Alejandro;
Krapf, Dario;
Krapf, Diego;
Darszon, Alberto;
Guerrero, Adán;
Buffone, Mariano G.

Publication type:

Article

Glucose and lactate regulate maitotoxin-activated Ca2+ entry in spermatogenic cells: The role of intracellular [Ca2+]

Published in:

FEBS Letters, 2010, v. 584, n. 14, p. 3111, doi. 10.1016/j.febslet.2010.05.051

By:

Reyes, Juan G.;
Osses, Nelson;
Knox, Marcela;
Darszon, Alberto;
Treviño, Claudia L.

Publication type:

Article

The SLO3 sperm-specific potassium channel plays a vital role in male fertility

Published in:

FEBS Letters, 2010, v. 584, n. 5, p. 1041, doi. 10.1016/j.febslet.2010.02.005

By:

Santi, Celia M.;
Martínez-López, Pablo;
de la Vega-Beltrán, José Luis;
Butler, Alice;
Alisio, Arturo;
Darszon, Alberto;
Salkoff, Lawrence

Publication type:

Article

Cholesterol-depleting compounds modulate K+-currents in Drosophila Kenyon cells

Published in:

FEBS Letters, 2005, v. 579, n. 23, p. 5129, doi. 10.1016/j.febslet.2005.08.022

By:

Gasque, Gabriel;
Labarca, Pedro;
Darszon, Alberto

Publication type:

Article

Expression and differential cell distribution of low-threshold Ca2+ channels in mammalian male germ cells and sperm

Published in:

FEBS Letters, 2004, v. 563, n. 1-3, p. 87, doi. 10.1016/S0014-5793(04)00257-1

By:

Treviño, Claudia L.;
Felix, Ricardo;
Castellano, Laura E.;
Gutiérrez, Carolina;
Rodríguez, Delany;
Pacheco, Judith;
López-González, Ignacio;
Gomora, Juan Carlos;
Tsutsumi, Victor;
Hernández-Cruz, Arturo;
Fiordelisio, Tatiana;
Scaling, Allison L.;
Darszon, Alberto

Publication type:

Article

Transient receptor potential (TRPC) channels in human sperm: expression, cellular localization and involvement in the regulation of flagellar motility

Published in:

FEBS Letters, 2003, v. 541, n. 1-3, p. 69, doi. 10.1016/S0014-5793(03)00305-3

By:

Castellano, Laura E.;
Treviño, Claudia L.;
Rodríguez, Delany;
Serrano, Carmen J.;
Pacheco, Judith;
Tsutsumi, Víctor;
Felix, Ricardo;
Darszon, Alberto

Publication type:

Article

T-type Ca channels in spermatogenic cells and sperm.

Published in:

Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 4, p. 819, doi. 10.1007/s00424-014-1478-2

By:

Darszon, Alberto;
Hernández-Cruz, Arturo

Publication type:

Article

CRISP1 as a novel CatSper regulator that modulates sperm motility and orientation during fertilization.

Published in:

Journal of Cell Biology, 2015, v. 210, n. 7, p. 1213, doi. 10.1083/jcb.201412041

By:

Ernesto, Juan I.;
Muñoz, Mariana Weigel;
Battistone, María A.;
Vasen, Gustavo;
Martínez-Lopez, Pablo;
Orta, Gerardo;
Figueiras-Fierro, Dulce;
De la Vega-Beltran, José L.;
Moreno, Ignacio A.;
Guidobaldi, Héctor A.;
Giojalas, Laura;
Darszon, Alberto;
Cohen, Débora J.;
Cuasnicú, Patricia S.

Publication type:

Article

Human spermatozoa possess a calcium-dependent chloride channel that may participate in the acrosomal reaction.

Published in:

Journal of Physiology, 2012, v. 590, n. 11, p. 2659, doi. 10.1113/jphysiol.2011.224485

By:

Orta, Gerardo;
Ferreira, Gonzalo;
José, Omar;
Treviño, Claudia L.;
Beltrán, Carmen;
Darszon, Alberto

Publication type:

Article

Ion channels, phosphorylation and mammalian sperm capacitation.

Published in:

Asian Journal of Andrology, 2011, v. 13, n. 3, p. 395, doi. 10.1038/aja.2010.69

By:

Visconti, Pablo E;
Krapf, Dario;
de la Vega-Beltrán, José Luis;
Acevedo, Juan José;
Darszon, Alberto

Publication type:

Article

The opening of maitotoxin-sensitive calcium channels induces the acrosome reaction in human spermatozoa: differences from the zona pellucida.

Published in:

Asian Journal of Andrology, 2011, v. 13, n. 1, p. 159, doi. 10.1038/aja.2010.80

By:

Chávez, Julio C;
de Blas, Gerardo A;
de la Vega-Beltrán, José L;
Nishigaki, Takuya;
Chirinos, Mayel;
González-González, María Elena;
Larrea, Fernando;
Solís, Alejandra;
Darszon, Alberto;
Treviño, Claudia L

Publication type:

Article

Reviewing mathematical models of sperm signaling networks.

Published in:

Molecular Reproduction & Development, 2024, v. 91, n. 8, p. 1, doi. 10.1002/mrd.23766

By:

Priego Espinosa, Daniel;
Espinal‐Enríquez, Jesús;
Aldana, Andrés;
Aldana, Maximino;
Martínez‐Mekler, Gustavo;
Carneiro, Jorge;
Darszon, Alberto

Publication type:

Article

Seeing is believing: Current methods to observe sperm acrosomal exocytosis in real time.

Published in:

Molecular Reproduction & Development, 2020, v. 87, n. 12, p. 1188, doi. 10.1002/mrd.23431

By:

Balestrini, Paula A.;
Jabloñski, Martina;
Schiavi‐Ehrenhaus, Liza J.;
Marín‐Briggiler, Clara I.;
Sánchez‐Cárdenas, Claudia;
Darszon, Alberto;
Krapf, Darío;
Buffone, Mariano G.

Publication type:

Article

Tyrosine phosphorylation signaling regulates Ca2+ entry by affecting intracellular pH during human sperm capacitation.

Published in:

Journal of Cellular Physiology, 2019, v. 234, n. 4, p. 5276, doi. 10.1002/jcp.27337

By:

Brukman, Nicolás Gastón;
Nuñez, Sol Yanel;
Puga Molina, Lis del Carmen;
Buffone, Mariano Gabriel;
Darszon, Alberto;
Cuasnicu, Patricia Sara;
Da Ros, Vanina Gabriela

Publication type:

Article

Acrosomal alkalization triggers Ca2+ release and acrosome reaction in mammalian spermatozoa.

Published in:

Journal of Cellular Physiology, 2018, v. 233, n. 6, p. 4735, doi. 10.1002/jcp.26262

By:

Chávez, Julio C.;
De la Vega‐Beltrán, José L.;
José, Omar;
Torres, Paulina;
Nishigaki, Takuya;
Treviño, Claudia L.;
Darszon, Alberto

Publication type:

Article

Essential Role of CFTR in PKA-Dependent Phosphorylation, Alkalinization, and Hyperpolarization During Human Sperm Capacitation.

Published in:

Journal of Cellular Physiology, 2017, v. 232, n. 6, p. 1404, doi. 10.1002/jcp.25634

By:

Puga Molina, Lis C.;
Pinto, Nicolás A.;
Torres Rodríguez, Paulina;
Romarowski, Ana;
Vicens Sanchez, Alberto;
Visconti, Pablo E.;
Darszon, Alberto;
Treviño, Claudia L.;
Buffone, Mariano G.

Publication type:

Article

Regulation of Spermatogenic Cell T-Type Ca2+ Currents by Zn2+: Implications in Male Reproductive Physiology.

Published in:

Journal of Cellular Physiology, 2016, v. 231, n. 3, p. 659, doi. 10.1002/jcp.25112

By:

López‐González, Ignacio;
Treviño, Claudia L.;
Darszon, Alberto

Publication type:

Article

Biphasic Role of Calcium in Mouse Sperm Capacitation Signaling Pathways.

Published in:

Journal of Cellular Physiology, 2015, v. 230, n. 8, p. 1758, doi. 10.1002/jcp.24873

By:

Navarrete, Felipe A.;
García‐Vázquez, Francisco A.;
Alvau, Antonio;
Escoffier, Jessica;
Krapf, Dario;
Sánchez‐Cárdenas, Claudia;
Salicioni, Ana M.;
Darszon, Alberto;
Visconti, Pablo E.

Publication type:

Article

Sodium influx induced by external calcium chelation decreases human sperm motility.

Published in:

2011

By:

Torres-Flores, Víctor;
Picazo-Juárez, Giovanni;
Hernández-Rueda, Yadira;
Darszon, Alberto;
González-Martínez, Marco T.

Publication type:

journal article

Bovine serum albumin‐induced calcium influx triggers soluble adenylyl cyclase activation and cyclic AMP signalling pathways in mouse sperm capacitation.

Published in:

Journal of Physiology, 2025, v. 603, n. 9, p. 2633, doi. 10.1113/JP288389

By:

Luque, Guillermina M.;
Jabloñski, Martina;
Schiavi‐Ehrenhaus, Liza J.;
del Prado, Rita C.;
Balbach, Melanie;
Romarowski, Ana;
Martin‐Hidalgo, David;
Visconti, Pablo E.;
Krapf, Dario;
Darszon, Alberto;
Krapf, Diego;
Buck, Jochen;
Levin, Lonny R.;
Buffone, Mariano G.

Publication type:

Article

Two‐pore channel 1 and Ca2+ release‐activated Ca2+ channels contribute to the acrosomal pH‐dependent intracellular Ca2+ increase in mouse sperm.

Published in:

Journal of Physiology, 2023, v. 601, n. 14, p. 2935, doi. 10.1113/JP284247

By:

Oliver, Enrique I.;
Jabloñski, Martina;
Buffone, Mariano G.;
Darszon, Alberto

Publication type:

Article

In Silico Determination of the Effect of Multi-Target Drugs on Calcium Dynamics Signaling Network Underlying Sea Urchin Spermatozoa Motility.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104451

By:

Espinal-Enríquez, Jesús;
Darszon, Alberto;
Guerrero, Adán;
Martínez-Mekler, Gustavo

Publication type:

Article

Ion Permeabilities in Mouse Sperm Reveal an External Trigger for SLO3-Dependent Hyperpolarization.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060578

By:

Chávez, Julio C.;
de la Vega-Beltrán, José L.;
Escoffier, Jessica;
Visconti, Pablo E.;
Treviño, Claudia L.;
Darszon, Alberto;
Salkoff, Lawrence;
Santi, Celia M.

Publication type:

Article

Discrete Dynamics Model for the Speract-Activated Ca2+ Signaling Network Relevant to Sperm Motility.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0022619

By:

Espinal, Jesús;
Aldana, Maximino;
Guerrero, Adán;
Wood, Christopher;
Darszon, Alberto;
Martínez-Mekler, Gustavo

Publication type:

Article

TRPM8, a Versatile Channel in Human Sperm.

Published in:

PLoS ONE, 2009, v. 4, n. 6, p. 1, doi. 10.1371/journal.pone.0006095

By:

De Blas, Gerardo A.;
Darszon, Alberto;
Ocampo, Ana Y.;
Serrano, Carmen J.;
Castellano, Laura E.;
Hernández-González, Enrique O.;
Chirinos, Mayel;
Larrea, Fernando;
Beltrán, Carmen;
Treviño, Claudia L.

Publication type:

Article

Modular analysis of the control of flagellar Ca2+-spike trains produced by CatSper and CaV channels in sea urchin sperm.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 3, p. 1, doi. 10.1371/journal.pcbi.1007605

By:

Priego-Espinosa, Daniel A.;
Darszon, Alberto;
Guerrero, Adán;
González-Cota, Ana Laura;
Nishigaki, Takuya;
Martínez-Mekler, Gustavo;
Carneiro, Jorge

Publication type:

Article

Multiple GTP-binding proteins in sea urchin sperm: Evidence for Gs and small G-proteins.

Published in:

Development, Growth & Differentiation, 1995, v. 37, n. 2, p. 173, doi. 10.1046/j.1440-169X.1995.t01-1-00006.x

By:

Cuéllar-Mata, Patricia;
Martínez-Cadena, Guadalupe;
Castellano, Laura E.;
Aldana-Veloz, Gustavo;
Vargas, Irma;
Darszon, Alberto;
García-Soto, Jesús

Publication type:

Article

Discrete Dynamic Model of the Mammalian Sperm Acrosome Reaction: The Influence of Acrosomal pH and Physiological Heterogeneity.

Published in:

Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.682790

By:

Aldana, Andrés;
Carneiro, Jorge;
Martínez-Mekler, Gustavo;
Darszon, Alberto

Publication type:

Article

Crosstalk between protein kinases A and C regulates sea urchin sperm motility.

Published in:

Zygote, 2022, v. 30, n. 3, p. 398, doi. 10.1017/S0967199421000915

By:

Loza-Huerta, Arlet;
Pacheco-Castillo, Hiram;
Darszon, Alberto;
Beltrán, Carmen

Publication type:

Article