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P4‐112: 38 CSF METABOLITES ARE HIGHLY PREDICTIVE OF CSF TOTAL TAU AND PHOSPHORYLATED TAU.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1318, doi. 10.1016/j.jalz.2019.06.3773
By:
- Dong, Ruocheng;
- Darst, Burcu F.;
- Lu, Qiongshi;
- Carlsson, Cynthia;
- Johnson, Sterling C.;
- Asthana, Sanjay;
- Engelman, Corinne D.
Publication type:
Article
P1‐133: THE ATN FRAMEWORK AND POLYGENIC SCORES OF AD ENDOPHENOTYPES.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P288, doi. 10.1016/j.jalz.2019.06.688
By:
- Robles, Yuetiva;
- Hunt, Jack F.V.;
- Lu, Qiongshi;
- Hohman, Timothy J.;
- Darst, Burcu F.;
- Farias, Fabiana H.G.;
- Cruchaga, Carlos;
- Asthana, Sanjay;
- Johnson, Sterling C.;
- Bendlin, Barbara B.;
- Engelman, Corinne D.
Publication type:
Article
P4‐274: THE GUT MICROBIOTA‐DERIVED METABOLITE TRIMETHYLAMINE N‐OXIDE (TMAO) IS ELEVATED IN ALZHEIMER'S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1551, doi. 10.1016/j.jalz.2018.07.096
By:
- Vogt, Nicholas M.;
- Romano, Kymberleigh;
- Darst, Burcu F.;
- Dong, Ruocheng;
- Engelman, Corinne D.;
- Johnson, Sterling C.;
- Carlsson, Cynthia M.;
- Asthana, Sanjay;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Bendlin, Barbara B.;
- Rey, Federico E.
Publication type:
Article
O3‐06‐03: TISSUE‐SPECIFIC POLYGENIC RISK SCORES PREDICT AMYLOID BIOMARKERS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1026, doi. 10.1016/j.jalz.2018.06.2802
By:
- Panyard, Daniel J.;
- Darst, Burcu F.;
- Koscik, Rebecca L.;
- Clark, Lindsay R.;
- Johnson, Sterling C.;
- Engelman, Corinne D.;
- Lu, Qiongshi
Publication type:
Article
O3‐03‐05: INTEGRATIVE NETWORK ANALYSIS IDENTIFIES RELATIONSHIPS BETWEEN METABOLOMICS, GENOMICS, AND RISK FACTORS FOR AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1016, doi. 10.1016/j.jalz.2018.06.2786
By:
- Darst, Burcu F.;
- Lu, Qiongshi;
- Koscik, Rebecca L.;
- Jonaitis, Erin;
- Clark, Lindsay R.;
- Hogan, Kirk J.;
- Johnson, Sterling C.;
- Engelman, Corinne D.
Publication type:
Article
P1‐136: THE LONGITUDINAL METABOLOMICS OF SEX, AGING, AND COGNITION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P324, doi. 10.1016/j.jalz.2018.06.139
By:
- Darst, Burcu F.;
- Koscik, Rebecca L.;
- Jonaitis, Erin;
- Clark, Lindsay R.;
- Hogan, Kirk J.;
- Johnson, Sterling C.;
- Engelman, Corinne D.
Publication type:
Article
The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer's disease.
Published in:
Alzheimer's Research & Therapy, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13195-018-0451-2
By:
- Vogt, Nicholas M.;
- Romano, Kymberleigh A.;
- Darst, Burcu F.;
- Engelman, Corinne D.;
- Johnson, Sterling C.;
- Carlsson, Cynthia M.;
- Asthana, Sanjay;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Bendlin, Barbara B.;
- Rey, Federico E.
Publication type:
Article
PRELIMINARY FINDINGS FROM AN ONGOING LONGITUDINAL METABOLOME-WIDE ASSOCIATION STUDY OF COGNITIVE DECLINE IN HEALTHY ADULTS WITH INCREASED RISK FOR ALZHEIMER’S DISEASE.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P551, doi. 10.1016/j.jalz.2017.07.149
By:
- Darst, Burcu F.;
- Rush, Matthew J.P.;
- Hutchins, Paul D.;
- Reddy, Thiruchelvi Rajagobal;
- Russell, Jason D.;
- Gangnon, Ronald;
- Koscik, Rebecca L.;
- Asthana, Sanjay;
- Johnson, Sterling C.;
- Hogan, Kirk J.;
- Coon, Joshua J.;
- Engelman, Corinne D.
Publication type:
Article
LONGEVITY GENE KLOTHO ALTERS APOE4-RELATED CORTICAL THINNING: FINDINGS FROM THE WISCONSIN REGISTRY FOR ALZHEIMER’S PREVENTION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P377, doi. 10.1016/j.jalz.2016.06.708
By:
- Schultz, Stephanie A.;
- Boots, Elizabeth A.;
- Oh, Jennifer M.;
- Darst, Burcu F.;
- Koscik, Rebecca L.;
- Gallagher, Catherine L.;
- Carlsson, Cynthia M.;
- Rowley, Howard A.;
- Bendlin, Barbara B.;
- Asthana, Sanjay;
- Sager, Mark A.;
- Hogan, Kirk J.;
- Hermann, Bruce P.;
- Engelman, Corinne D.;
- Johnson, Sterling C.;
- Dubal, Dena B.;
- Okonkwo, Ozioma C.
Publication type:
Article
LONGEVITY GENE KLOTHO ALTERS APOE4-RELATED CORTICAL THINNING: FINDINGS FROM THE WISCONSIN REGISTRY FOR ALZHEIMER’S PREVENTION.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P56, doi. 10.1016/j.jalz.2016.06.101
By:
- Schultz, Stephanie A.;
- Boots, Elizabeth A.;
- Oh, Jennifer M.;
- Darst, Burcu F.;
- Koscik, Rebecca L.;
- Gallagher, Catherine L.;
- Carlsson, Cynthia M.;
- Rowley, Howard A.;
- Bendlin, Barbara B.;
- Asthana, Sanjay;
- Sager, Mark A.;
- Hogan, Kirk J.;
- Hermann, Bruce P.;
- Engelman, Corinne D.;
- Johnson, Sterling C.;
- Dubal, Dena B.;
- Okonkwo, Ozioma C.
Publication type:
Article
Effect of TREM2 and PLD3 in an Alzheimer’s disease family history cohort: The wisconsin registry for Alzheimer's prevention (WRAP).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P854, doi. 10.1016/j.jalz.2015.08.021
By:
- Engelman, Corinne D.;
- Darst, Burcu F.;
- Koscik, Rebecca L.;
- Johnson, Sterling C.
Publication type:
Article
Cardiorespiratory capacity modifies the association between a polygenic risk score and CSF biomarkers in preclinical Alzheimer’s disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P766, doi. 10.1016/j.jalz.2015.06.064
By:
- Schultz, Stephanie A.;
- Boots, Elizabeth A.;
- Dougherty, Ryan J.;
- Darst, Burcu F.;
- Yu, Sherman;
- Kirby, Taylor;
- Edwards, Dorothy Farrar;
- Einerson, Jean A.;
- Korcarz, Claudia E.;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Carlsson, Cynthia M.;
- Bendlin, Barbara B.;
- Asthana, Sanjay;
- Sager, Mark A.;
- Hermann, Bruce P.;
- Johnson, Sterling C.;
- Stein, James H.;
- Engelman, Corinne D.;
- Cook, Dane B.
Publication type:
Article
Cardiorespiratory capacity modifies the association between a polygenic risk score and CSF biomarkers in preclinical Alzheimer’s disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P37, doi. 10.1016/j.jalz.2015.06.064
By:
- Schultz, Stephanie A.;
- Boots, Elizabeth A.;
- Dougherty, Ryan J.;
- Darst, Burcu F.;
- Yu, Sherman;
- Kirby, Taylor;
- Edwards, Dorothy Farrar;
- Einerson, Jean A.;
- Korcarz, Claudia E.;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Carlsson, Cynthia M.;
- Bendlin, Barbara B.;
- Asthana, Sanjay;
- Sager, Mark A.;
- Hermann, Bruce P.;
- Johnson, Sterling C.;
- Stein, James H.;
- Engelman, Corinne D.;
- Cook, Dane B.
Publication type:
Article
Multi-ethnic GWAS and fine-mapping of glycaemic traits identify novel loci in the PAGE Study.
Published in:
Diabetologia, 2022, v. 65, n. 3, p. 477, doi. 10.1007/s00125-021-05635-9
By:
- Downie, Carolina G.;
- Dimos, Sofia F.;
- Bien, Stephanie A.;
- Hu, Yao;
- Darst, Burcu F.;
- Polfus, Linda M.;
- Wang, Yujie;
- Wojcik, Genevieve L.;
- Tao, Ran;
- Raffield, Laura M.;
- Armstrong, Nicole D.;
- Polikowsky, Hannah G.;
- Below, Jennifer E.;
- Correa, Adolfo;
- Irvin, Marguerite R.;
- Rasmussen-Torvik, Laura J. F.;
- Carlson, Christopher S.;
- Phillips, Lawrence S.;
- Liu, Simin;
- Pankow, James S.
Publication type:
Article
Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.78304
By:
- Fei Chen;
- Darst, Burcu F.;
- Madduri, Ravi K.;
- Rodriguez, Alex A.;
- Xin Sheng;
- Rentsch, Christopher T.;
- Andrews, Caroline;
- Wei Tang;
- Kibel, Adam S.;
- Plym, Anna;
- Cho, Kelly;
- Jalloh, Mohamed;
- Gueye, Serigne Magueye;
- Niang, Lamine;
- Ogunbiyi, Olufemi J.;
- Popoola, Olufemi;
- Adebiyi, Akindele O.;
- Aisuodionoe-Shadrach, Oseremen I.;
- Ajibola, Hafees O.;
- Jamda, Mustapha A.
Publication type:
Article
Validation of a multi-ancestry polygenic risk score and age-specific risks of prostate cancer: A meta-analysis within diverse populations.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.78304
By:
- Fei Chen;
- Darst, Burcu F.;
- Madduri, Ravi K.;
- Rodriguez, Alex A.;
- Xin Sheng;
- Rentsch, Christopher T.;
- Andrews, Caroline;
- Wei Tang;
- Kibel, Adam S.;
- Plym, Anna;
- Cho, Kelly;
- Jalloh, Mohamed;
- Gueye, Serigne Magueye;
- Niang, Lamine;
- Ogunbiyi, Olufemi J.;
- Popoola, Olufemi;
- Adebiyi, Akindele O.;
- Aisuodionoe-Shadrach, Oseremen I.;
- Ajibola, Hafees O.;
- Jamda, Mustapha A.
Publication type:
Article
Genome-wide association study of pancreatic fat: The Multiethnic Cohort Adiposity Phenotype Study.
Published in:
PLoS ONE, 2021, v. 16, n. 7, p. 1, doi. 10.1371/journal.pone.0249615
By:
- Streicher, Samantha A.;
- Lim, Unhee;
- Park, S. Lani;
- Li, Yuqing;
- Sheng, Xin;
- Hom, Victor;
- Xia, Lucy;
- Pooler, Loreall;
- Shepherd, John;
- Loo, Lenora W. M.;
- Darst, Burcu F.;
- Highland, Heather M.;
- Polfus, Linda M.;
- Bogumil, David;
- Ernst, Thomas;
- Buchthal, Steven;
- Franke, Adrian A.;
- Setiawan, Veronica Wendy;
- Tiirikainen, Maarit;
- Wilkens, Lynne R.
Publication type:
Article
Using recursive feature elimination in random forest to account for correlated variables in high dimensional data.
Published in:
BMC Genetics, 2018, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12863-018-0633-8
By:
- Darst, Burcu F.;
- Malecki, Kristen C.;
- Engelman, Corinne D.
Publication type:
Article
Cerebrospinal fluid metabolomics identifies 19 brain-related phenotype associations.
Published in:
Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-020-01583-z
By:
- Panyard, Daniel J.;
- Kim, Kyeong Mo;
- Darst, Burcu F.;
- Deming, Yuetiva K.;
- Zhong, Xiaoyuan;
- Wu, Yuchang;
- Kang, Hyunseung;
- Carlsson, Cynthia M.;
- Johnson, Sterling C.;
- Asthana, Sanjay;
- Engelman, Corinne D.;
- Lu, Qiongshi
Publication type:
Article
Biobank-wide association scan identifies risk factors for late-onset Alzheimer’s disease and endophenotypes.
Published in:
eLife, 2024, p. 1, doi. 10.7554/eLife.91360
By:
- Donghui Yan;
- Bowen Hu;
- Darst, Burcu F.;
- Mukherjee, Shubhabrata;
- Kunkle, Brian W.;
- Yuetiva Deming;
- Dumitrescu, Logan;
- Yunling Wang;
- Naj, Adam;
- Kuzma, Amanda;
- Yi Zhao;
- Hyunseung Kang;
- Johnson, Sterling C.;
- Carlos, Cruchaga;
- Hohman, Timothy J.;
- Crane, Paul K.;
- Engelman, Corinne D.;
- Qiongshi Lu
Publication type:
Article
Prioritization of family member sequencing for the detection of rare variants.
Published in:
BMC Proceedings, 2016, v. 10, p. 227, doi. 10.1186/s12919-016-0035-8
By:
- Sippy, Rachel;
- Kolesar, Jill M.;
- Darst, Burcu F.;
- Engelman, Corinne D.
Publication type:
Article
Transmission and decorrelation methods for detecting rare variants using sequencing data from related individuals.
Published in:
BMC Proceedings, 2016, v. 10, p. 203, doi. 10.1186/s12919-016-0031-z
By:
- Darst, Burcu F.;
- Engelman, Corinne D.
Publication type:
Article
Direct-to-consumer personalized genomic testing.
Published in:
Human Molecular Genetics, 2011, v. 20, n. R2, p. R132, doi. 10.1093/hmg/ddr349
By:
- Bloss, Cinnamon S.;
- Darst, Burcu F.;
- Topol, Eric J.;
- Schork, Nicholas J.
Publication type:
Article
CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status.
Published in:
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021, v. 13, n. 1, p. 1, doi. 10.1002/dad2.12167
By:
- Dong, Ruocheng;
- Darst, Burcu F.;
- Deming, Yuetiva;
- Ma, Yue;
- Lu, Qiongshi;
- Zetterberg, Henrik;
- Blennow, Kaj;
- Carlsson, Cynthia M.;
- Johnson, Sterling C.;
- Asthana, Sanjay;
- Engelman, Corinne D.
Publication type:
Article
Hierarchical joint analysis of marginal summary statistics—Part II: High‐dimensional instrumental analysis of omics data.
Published in:
Genetic Epidemiology, 2024, v. 48, n. 7, p. 291, doi. 10.1002/gepi.22577
By:
- Jiang, Lai;
- Shen, Jiayi;
- Darst, Burcu F.;
- Haiman, Christopher A.;
- Mancuso, Nicholas;
- Conti, David V.
Publication type:
Article
Including diverse and admixed populations in genetic epidemiology research.
Published in:
Genetic Epidemiology, 2022, v. 46, n. 7, p. 347, doi. 10.1002/gepi.22492
By:
- Caliebe, Amke;
- Tekola‐Ayele, Fasil;
- Darst, Burcu F.;
- Wang, Xuexia;
- Song, Yeunjoo E.;
- Gui, Jiang;
- Sebro, Ronnie A.;
- Balding, David J.;
- Saad, Mohamad;
- Dubé, Marie‐Pierre
Publication type:
Article
Cover Image.
Published in:
Genetic Epidemiology, 2019, v. 43, n. 6, p. i, doi. 10.1002/gepi.22253
By:
- Darst, Burcu F.;
- Lu, Qiongshi;
- Johnson, Sterling C.;
- Engelman, Corinne D.
Publication type:
Article
Integrated analysis of genomics, longitudinal metabolomics, and Alzheimer's risk factors among 1,111 cohort participants.
Published in:
Genetic Epidemiology, 2019, v. 43, n. 6, p. 657, doi. 10.1002/gepi.22211
By:
- Darst, Burcu F.;
- Lu, Qiongshi;
- Johnson, Sterling C.;
- Engelman, Corinne D.
Publication type:
Article
RE: Polygenic risk of any, metastatic, and fatal prostate cancer in the Million Veteran Program.
Published in:
JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 3, p. 341, doi. 10.1093/jnci/djad005
By:
- Haiman, Christopher A;
- Kote-Jarai, Zsofia;
- Darst, Burcu F;
- Conti, David V
Publication type:
Article
Germline Sequencing DNA Repair Genes in 5545 Men With Aggressive and Nonaggressive Prostate Cancer.
Published in:
2021
By:
- Darst, Burcu F;
- Dadaev, Tokhir;
- Saunders, Ed;
- Sheng, Xin;
- Wan, Peggy;
- Pooler, Loreall;
- Xia, Lucy Y;
- Chanock, Stephen;
- Berndt, Sonja I;
- Gapstur, Susan M;
- Stevens, Victoria;
- Albanes, Demetrius;
- Weinstein, Stephanie J;
- Gnanapragasam, Vincent;
- Giles, Graham G;
- Nguyen-Dumont, Tu;
- Milne, Roger L;
- Pomerantz, Mark;
- Schmidt, Julie A;
- Mucci, Lorelei
Publication type:
journal article
198-LB: Pleiotropy Analysis of Adiposity, Glycemic, and Renal Traits in the Population Architecture Using Genomics in Epidemiology (PAGE) Consortium.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-198-LB
By:
- HIGHLAND, HEATHER M.;
- DOWNIE, CAROLINA;
- DIMOS, SOFIA F.;
- GRAFF, MARIAELISA;
- POLFUS, LINDA M.;
- DARST, BURCU F.;
- BALDASSARI, ANTOINE R.M.;
- SITLANI, COLLEEN;
- HOWARD, ANNIE GREEN;
- KOOPERBERG, CHARLES L.;
- LOOS, RUTH;
- MATISE, TARA;
- MOTTL, AMY K.;
- NORTH, KARI E.;
- AVERY, CHRISTY L.
Publication type:
Article
Sign-based Shrinkage Based on an Asymmetric LASSO Penalty.
Published in:
Journal of Data Science, 2021, v. 19, n. 3, p. 429, doi. 10.6339/21-JDS1015
By:
- KAWAGUCHI, ERIC S.;
- DARST, BURCU F.;
- KAN WANG;
- CONTI, DAVID V.
Publication type:
Article

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